-
1
-
-
0018800089
-
A rapid alkaline extraction procedure for screening recombinant plasmid DNA
-
Birnboim HC, Doly J. 1979. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res 7:1513-1523.
-
(1979)
Nucleic Acids Res
, vol.7
, pp. 1513-1523
-
-
Birnboim, H.C.1
Doly, J.2
-
3
-
-
33846936490
-
-
Chamsart S. 2001. A cell lysis reactor for the production of plasmid DNA from recombinant E. coli for gene therapy. Ph.D. Thesis, School of Chemical Engineering, The University of Birmingham, U.K.
-
Chamsart S. 2001. A cell lysis reactor for the production of plasmid DNA from recombinant E. coli for gene therapy. Ph.D. Thesis, School of Chemical Engineering, The University of Birmingham, U.K.
-
-
-
-
4
-
-
0035923311
-
The impact of fluid-dynamic-generated stress on chDNA and pDNA stability during alkaline cell lysis for gene therapy products
-
Chamsart S, Patel H, Hanak JAJ, Hitchcock AG, Nienow AW. 2001. The impact of fluid-dynamic-generated stress on chDNA and pDNA stability during alkaline cell lysis for gene therapy products. Biotechnol Bioeng 75:387-392.
-
(2001)
Biotechnol Bioeng
, vol.75
, pp. 387-392
-
-
Chamsart, S.1
Patel, H.2
Hanak, J.A.J.3
Hitchcock, A.G.4
Nienow, A.W.5
-
5
-
-
0032311833
-
Time course of SDS alkaline lysis of recombinant bacterial cells for plasmid release
-
Ciccolini LAS, Ayazi Shamlou P, Titchener-Hooker NJ, Ward JM, Dunnill P. 1998. Time course of SDS alkaline lysis of recombinant bacterial cells for plasmid release. Biotechnol Bioeng 60:768-770.
-
(1998)
Biotechnol Bioeng
, vol.60
, pp. 768-770
-
-
Ciccolini, L.A.S.1
Ayazi Shamlou, P.2
Titchener-Hooker, N.J.3
Ward, J.M.4
Dunnill, P.5
-
6
-
-
0032841890
-
Rheological properties of chromosomal and plasmid DNA during alkaline lysis reaction
-
Ciccolini LAS, Ayazi Shamlou P, Titchener-Hooker NJ, Ward JM, Dunnill P. 1999. Rheological properties of chromosomal and plasmid DNA during alkaline lysis reaction. Bioprocess Eng 21:231-237.
-
(1999)
Bioprocess Eng
, vol.21
, pp. 231-237
-
-
Ciccolini, L.A.S.1
Ayazi Shamlou, P.2
Titchener-Hooker, N.J.3
Ward, J.M.4
Dunnill, P.5
-
7
-
-
33846915954
-
-
Cole-Parmer. 2003, Cole-Parmer Catalogue, Cole-Parmer Instrument Co.625 East Bunker Court Vernon Hills, IL USA.
-
Cole-Parmer. 2003, Cole-Parmer Catalogue, Cole-Parmer Instrument Co.625 East Bunker Court Vernon Hills, IL USA.
-
-
-
-
8
-
-
0027248058
-
A modified alkaline lysis method for the precipitation of high purified plasmid DNA from E. coli
-
Feliciello I, Chinali G. 1993. A modified alkaline lysis method for the precipitation of high purified plasmid DNA from E. coli. Analytical Biochem 212:394-401.
-
(1993)
Analytical Biochem
, vol.212
, pp. 394-401
-
-
Feliciello, I.1
Chinali, G.2
-
9
-
-
0033167256
-
Development of process flow sheets for the purification of supercoiled plasmids for gene therapy applications
-
Ferreira GNM, Cabral JMS, Prazeres DMF. 1999. Development of process flow sheets for the purification of supercoiled plasmids for gene therapy applications. Biotechnol Progr 15:725-731.
-
(1999)
Biotechnol Progr
, vol.15
, pp. 725-731
-
-
Ferreira, G.N.M.1
Cabral, J.M.S.2
Prazeres, D.M.F.3
-
10
-
-
0343786501
-
-
a Practical Approach. Oxford: IRL Press
-
Glover DM. 1985. DNA Cloning Vol. II a Practical Approach. Oxford: IRL Press.
-
(1985)
DNA Cloning
, vol.2
-
-
Glover, D.M.1
-
11
-
-
33846909486
-
-
Private communication. Cobra Therapeutics Ltd
-
Hitchcock AG. 1997. Private communication. Cobra Therapeutics Ltd.
-
(1997)
-
-
Hitchcock, A.G.1
-
12
-
-
0028978028
-
Cancer gene therapy using plasmid DNA: Purification of DNA for human clinical trials
-
Horn NA, Meek JA, Budahazi G, Marquet M. 1995. Cancer gene therapy using plasmid DNA: Purification of DNA for human clinical trials. Human Gene Therapy 6:565-573.
-
(1995)
Human Gene Therapy
, vol.6
, pp. 565-573
-
-
Horn, N.A.1
Meek, J.A.2
Budahazi, G.3
Marquet, M.4
-
13
-
-
0034609044
-
Purification of plasmid DNA by tangential flow filtration
-
Kahn DW, Butler MD, Cohen DL, Gordon M, Kahn JW, Winkler ME. 2000. Purification of plasmid DNA by tangential flow filtration. Biotechnol Bioeng 69:101-106.
-
(2000)
Biotechnol Bioeng
, vol.69
, pp. 101-106
-
-
Kahn, D.W.1
Butler, M.D.2
Cohen, D.L.3
Gordon, M.4
Kahn, J.W.5
Winkler, M.E.6
-
14
-
-
33846910807
-
A method for large scale plasmid purification
-
International Patent Application No. WO 96/36706
-
Lee AL, Sagar S. 1999. A method for large scale plasmid purification. International Patent Application No. WO 96/36706.
-
(1999)
-
-
Lee, A.L.1
Sagar, S.2
-
15
-
-
0033067995
-
Effect of shear on plasmid DNA in solution
-
Levy MS, Collins IJ, Yim SS, Ward JM, Titchener-Hooker N, Shamlou PA, Dunnill P. 1999. Effect of shear on plasmid DNA in solution. Bioprocess Eng 20:7-13.
-
(1999)
Bioprocess Eng
, vol.20
, pp. 7-13
-
-
Levy, M.S.1
Collins, I.J.2
Yim, S.S.3
Ward, J.M.4
Titchener-Hooker, N.5
Shamlou, P.A.6
Dunnill, P.7
-
16
-
-
0034237305
-
Biochemical engineering approaches to the challenges of producing pure plasmid DNA
-
Levy MS, O'Kennedy RD, Ayazi P, Dunnill P. 2000. Biochemical engineering approaches to the challenges of producing pure plasmid DNA. Trends Biotechnol 8:296-304.
-
(2000)
Trends Biotechnol
, vol.8
, pp. 296-304
-
-
Levy, M.S.1
O'Kennedy, R.D.2
Ayazi, P.3
Dunnill, P.4
-
17
-
-
0020121736
-
A procedure for the large-scale isolation of high purified plasmid DNA using alkaline extraction and binding to glass powder
-
Marko MA, Chipperfield R, Birnboim HC. 1982. A procedure for the large-scale isolation of high purified plasmid DNA using alkaline extraction and binding to glass powder. Analytical Biochem 121:382-387.
-
(1982)
Analytical Biochem
, vol.121
, pp. 382-387
-
-
Marko, M.A.1
Chipperfield, R.2
Birnboim, H.C.3
-
18
-
-
85010439719
-
A procedure for the isolation of deoxyribonucleic acid from micro-organisms
-
Marmur J. 1961. A procedure for the isolation of deoxyribonucleic acid from micro-organisms. J Mol Biol 3:208-218.
-
(1961)
J Mol Biol
, vol.3
, pp. 208-218
-
-
Marmur, J.1
-
19
-
-
0001875768
-
Process development of the manufacture of plasmid DNA vector for use in gene therapy
-
Marquet M, Horn NA, Meek JA. 1995. Process development of the manufacture of plasmid DNA vector for use in gene therapy. BioPharm 8:26-37.
-
(1995)
BioPharm
, vol.8
, pp. 26-37
-
-
Marquet, M.1
Horn, N.A.2
Meek, J.A.3
-
20
-
-
33846922771
-
-
1996. Production of plasmid DNA for non-viral gene therapy. Cobra Therapeutics Ltd, Private Communication, The Science Park, Keele Staffordshire
-
Matthew GB, Hitchcock AG, Varley DL, Hanak JAJ, Thatcher DR. 1996. Production of plasmid DNA for non-viral gene therapy. Cobra Therapeutics Ltd., Private Communication, The Science Park, Keele Staffordshire.
-
-
-
Matthew, G.B.1
Hitchcock, A.G.2
Varley, D.L.3
Hanak, J.A.J.4
Thatcher, D.R.5
-
21
-
-
24044441888
-
Proposal for a better integration of bacterial lysis into the production of plasmid DNA at large scale
-
O'Mahony K, Freitag R, Hilbrig F, Müller P, Schumacher I. 2005. Proposal for a better integration of bacterial lysis into the production of plasmid DNA at large scale. J Biotechnol 119:118-132.
-
(2005)
J Biotechnol
, vol.119
, pp. 118-132
-
-
O'Mahony, K.1
Freitag, R.2
Hilbrig, F.3
Müller, P.4
Schumacher, I.5
-
22
-
-
0032496250
-
Preparative purification of supercoiled plasmid DNA using anion exchange chromatography
-
Prazeres DMF, Schluep T, Cooney C. 1998. Preparative purification of supercoiled plasmid DNA using anion exchange chromatography. J Chromatogr 806:31-45.
-
(1998)
J Chromatogr
, vol.806
, pp. 31-45
-
-
Prazeres, D.M.F.1
Schluep, T.2
Cooney, C.3
-
23
-
-
0033120652
-
Large-scale production of pharmaceutical-grade plasmid DNA for gene therapy: Problems and bottlenecks
-
Prazeres DMF, Ferreira GNM, Monterio GA, Cooney CL, Cabral JMS. 1999. Large-scale production of pharmaceutical-grade plasmid DNA for gene therapy: Problems and bottlenecks. Trends Biotechnol 17:169-174.
-
(1999)
Trends Biotechnol
, vol.17
, pp. 169-174
-
-
Prazeres, D.M.F.1
Ferreira, G.N.M.2
Monterio, G.A.3
Cooney, C.L.4
Cabral, J.M.S.5
-
26
-
-
0023710261
-
Large-scale isolation of covalently closed circular DNA using gel filtration chromatography
-
Raymond GJ, Kruger BP, Nelson A, Johnson JD. 1988. Large-scale isolation of covalently closed circular DNA using gel filtration chromatography. Analytical Biochem 173:125-133.
-
(1988)
Analytical Biochem
, vol.173
, pp. 125-133
-
-
Raymond, G.J.1
Kruger, B.P.2
Nelson, A.3
Johnson, J.D.4
-
27
-
-
0033377045
-
Production of plasmid DNA for human gene therapy using modified alkaline cell lysis and expanded bed anion exchange chromatography
-
Sharpe GS, Thatcher DR, Hanak JAJ. 1999. Production of plasmid DNA for human gene therapy using modified alkaline cell lysis and expanded bed anion exchange chromatography. Bioseparation 8:209-217.
-
(1999)
Bioseparation
, vol.8
, pp. 209-217
-
-
Sharpe, G.S.1
Thatcher, D.R.2
Hanak, J.A.J.3
-
28
-
-
0030560909
-
The effect of impeller types of floc size and structure during shear-induced flocculation
-
Spicer PT, Keller W, Pratsinis SE. 1996. The effect of impeller types of floc size and structure during shear-induced flocculation. J Colloid Interface Sci 184:112-122.
-
(1996)
J Colloid Interface Sci
, vol.184
, pp. 112-122
-
-
Spicer, P.T.1
Keller, W.2
Pratsinis, S.E.3
-
29
-
-
0141750575
-
Static mixers in the process industries - A Review. Trans IChemE
-
Thakur RK, Vial Ch, Nigam KDP, Nauman EB, Djelveh G. 2003. Static mixers in the process industries - A Review. Trans IChemE, Institution of Chemical Engineers 81:787-826.
-
(2003)
Institution of Chemical Engineers
, vol.81
, pp. 787-826
-
-
Thakur, R.K.1
Vial, C.2
Nigam, K.D.P.3
Nauman, E.B.4
Djelveh, G.5
-
30
-
-
0031043783
-
The processing of a plasmid-based gene from E. coli: Primary recovery by filtration
-
Theodossiou I, Collins IJ, Ward JM, Thomas ORT, Dunnill P. 1997. The processing of a plasmid-based gene from E. coli: Primary recovery by filtration. Bioprocess Eng 16:175-183.
-
(1997)
Bioprocess Eng
, vol.16
, pp. 175-183
-
-
Theodossiou, I.1
Collins, I.J.2
Ward, J.M.3
Thomas, O.R.T.4
Dunnill, P.5
-
31
-
-
0033003354
-
Methods for enhancing the recovery of plasmid genes from neutralised cell lysate
-
Theodossiou I, Thomas ORT, Dunnill P. 1999. Methods for enhancing the recovery of plasmid genes from neutralised cell lysate. Bioprocess Eng 20:147-156.
-
(1999)
Bioprocess Eng
, vol.20
, pp. 147-156
-
-
Theodossiou, I.1
Thomas, O.R.T.2
Dunnill, P.3
-
32
-
-
0033377045
-
Production of plasmid DNA for human gene therapy using modified alkaline cell lysis and expanded bed anion exchange chromatography
-
Varley DL, Hitchcock AG, Weiss AME, Horler WA, Cowell R, Peddie L, Sharpe GS, Thatcher DR, Hanak JAJ. 1999. Production of plasmid DNA for human gene therapy using modified alkaline cell lysis and expanded bed anion exchange chromatography. Bioseparation 8:209-217.
-
(1999)
Bioseparation
, vol.8
, pp. 209-217
-
-
Varley, D.L.1
Hitchcock, A.G.2
Weiss, A.M.E.3
Horler, W.A.4
Cowell, R.5
Peddie, L.6
Sharpe, G.S.7
Thatcher, D.R.8
Hanak, J.A.J.9
-
33
-
-
0036808007
-
Studies on recovery plasmid DNA from Escherichia coli by heat treatment
-
Wang Z, Le G, Shi Y, Wegrzyn G. 2002. Studies on recovery plasmid DNA from Escherichia coli by heat treatment. Process Biochem 38:199-206.
-
(2002)
Process Biochem
, vol.38
, pp. 199-206
-
-
Wang, Z.1
Le, G.2
Shi, Y.3
Wegrzyn, G.4
-
34
-
-
0030979103
-
Efficient purification of plasmid DNA for gene transfer using triple-helix affinity chromatography
-
Wills P, Warnery V, Lacroix F, Langneaux D, Ollivier M, Crouzet J, Mayaux JF, Scherma D. 1997. Efficient purification of plasmid DNA for gene transfer using triple-helix affinity chromatography. Gene Therapy 4:323-330.
-
(1997)
Gene Therapy
, vol.4
, pp. 323-330
-
-
Wills, P.1
Warnery, V.2
Lacroix, F.3
Langneaux, D.4
Ollivier, M.5
Crouzet, J.6
Mayaux, J.F.7
Scherma, D.8
-
35
-
-
0035686470
-
Extraction of plasmid DNA using reactor scale alkaline lysis and selective precipitation for scaleable transient transfection
-
Wright JL, Jordan M, Wurm FM. 2001. Extraction of plasmid DNA using reactor scale alkaline lysis and selective precipitation for scaleable transient transfection. Cytotechnology 35:165-173.
-
(2001)
Cytotechnology
, vol.35
, pp. 165-173
-
-
Wright, J.L.1
Jordan, M.2
Wurm, F.M.3
-
36
-
-
0025898641
-
A simple and economical procedure for large-scale plasmid isolation
-
Yang WK, Henley DC. 1991. A simple and economical procedure for large-scale plasmid isolation. Nucleic Acids Res 19:25-32.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 25-32
-
-
Yang, W.K.1
Henley, D.C.2
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