Asymmetric suppression of components in binary aldehyde mixtures: Behavioral studies in the laboratory rat

Chemical Senses

Volumn 32, Issue 2, 2007, Pages 191-199

  Sokolic, Ljiljana ^a   Laing, David G ^b   McGregor, Iain S ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Aliphatic aldehydes; Discrimination; Odor mixtures; Odor suppression; Olfactometer; Rats

Indexed keywords

ALDEHYDE; BUTYRALDEHYDE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DISCRIMINATION LEARNING; MALE; NONHUMAN; OLFACTOMETER; OLFACTORY DISCRIMINATION; PRIORITY JOURNAL; RAT; REWARD; SCORING SYSTEM; STIMULUS RESPONSE;

ALDEHYDES; ANIMALS; BEHAVIOR, ANIMAL; BINDING, COMPETITIVE; DISCRIMINATION (PSYCHOLOGY); DRUG COMBINATIONS; ODORS; RATS; RECEPTORS, CELL SURFACE; SENSORY THRESHOLDS; SMELL;

RATTUS; RATTUS NORVEGICUS; RODENTIA;

EID: 33846897173     PISSN: 0379864X     EISSN: 14643553     Source Type: Journal    
DOI: 10.1093/chemse/bjl049     Document Type: Article

References (30)

1. Ache BW. 1989. Central and peripheral basis for mixture suppression in olfaction: A crustacean model. In: Laing DG, McBride RL, Ache BW, editors. Perception of complex smells and tastes. Sydney (Australia): Academic Press. p. 101-114.
2. Araneda RC, Kini AD, Firestein S. 2000. The molecular receptive range of an odorant receptor. Nat Neurosci. 3:1248-1255.
3. Araneda RC, Peterlin Z, Zhang X, Chesler A, Firestein S. 2004. A pharmacological profile of the aldehyde receptor repertoire in rat olfactory epithelium. J Physiol (Lond). 555:743-756.
4. Bell GA, Laing DG, Panhuber H. 1987. Odour mixture suppression: Evidence for a peripheral mechanism in human and rat. Brain Res. 426:8-18.
5. Deisig N, Giurfa M, Lachnit H, Sandoz JC. 2006. Neural representation of olfactory mixtures in the honeybee antennal lobe. Eur J Neurosci. 24:1161-1174.
6. Derby CD. 2000. Learning from spiny lobsters about chemosensory coding of mixtures. Physiol Behav. 69:203-209.
7. Duchamp-Viret P, Duchamp A, Chaput MA. 2003. Single olfactory sensory neurons simultaneously integrate the components of an odour mixture. Eur J Neurosci. 18:2690-2696.
8. Eayrs JT, Moulton DG. 1960. Studies in olfactory acuity. I. Measurements of olfactory thresholds in the rat. Q J Exp Psychol. 12:90-98.
9. Joerges J, Küttner A, Galizia CG. 1997. Representations of odours and odours mixtures visualized in the honeybee brain. Nature. 387:285-288.
10. Kay LM, Crk T, Thorngate J. 2005. A redefinition of odor mixture quality. Behav Neurosci. 119:726-733.
11. Kay LM, Krysiak M, Barlas L, Edgerton GB. 2006. Grading odor similarities in a go/no-go task. Physiol Behav. 88:339-346.
12. Kay LM, Lowry CA, Jacobs HA. 2003. Receptor contributions to configural and elemental odor mixture perception. Behav Neurosci. 117:1108-1114.
13. Laing DG, Francis GW. 1989. The capacity of humans to identify odors in mixtures. Physiol Behav. 46:809-814.
14. Laing DG, Jinks AL, Segovia C, Hutchinson I. 2002. Systematic changes in the types of odor interactions are related to the molecular structure of the components. 24th Annual Meeting Association for Chemoreception Sciences; 2002 Apr 24-28; Sarasota, FL.
15. Laing DG, Panhuber H, Slotnick BM. 1989. Odor masking in the rat. Physiol Behav. 45:689-694.
16. Laing DG, Panhuber H,Willcox ME, Pittman EA. 1984. Quality and intensity of binary odor mixtures. Physiol Behav. 33:309-319.
17. Laska M, Joshi D, Shepherd GM. 2006. Olfactory sensitivity for aliphatic aldehydes in CD-1 mice. Behav Brain Res. 167:349-354.
18. Laska M, Trolp S, Teubner P. 1999. Odor structure-activity relationships compared inhumanand nonhuman primates. Behav Neurosci. 113:998-1007.
19. Linster C, Cleland TA. 2004. Configurational and elemental odor mixture perception can arise from local inhibition. J Comput Neurosci. 16: 39-47.
20. Linster C, Hasselmo ME. 1999. Behavioral responses to aliphatic aldehydes can be predicted from known electrophysiological responses of mitral cells in the olfactory bulb. Physiol Behav. 66: 497-502.
21. Linster C, Smith BH. 1999. Generalization between binary odor mixtures and their components in the rat. Physiol Behav. 66:701-707.
22. McGregor I. 1996. Using Strawberry Tree Workbench Mac and Workbench PC software for data acquisition and control in the animal learning laboratory. Behav Res Methods Instrum Comput. 28: 38-48.
23. Moulton DG, Eayrs JT. 1960. Studies in olfactory acuity. II. Relative detectability of n-aliphatic alcohols. Q J Exp Psychol. 12:99-109.
24. Slotnick BM, Bodyak N. 2002. Odor discrimination and odor quality perception in rats with disruption of connections between the olfactory epithelium and olfactory bulbs. J Neurosci. 22:4205-4216.
25. Slotnick BM, Schellinck H. 2001. Methods in olfactory research with rodents. In: Simon SA, Nicolelis M. editors. Frontiers and methods in chemosenses. Washington (DC): CRC Press. p. 21-61.
26. Slotnick BM, Schoonover FW. 1984. Olfactory thresholds in unilaterally bulbectomized rats. Chemical Senses. 9:325-340.
27. Tabor R, Yaksi E, Weislogel JM, Friedrich RW. 2004. Processing of odor mixtures in the zebrafish olfactory bulb. J Neurosci. 24:6611-6620.
28. Wilson DA. 2003. Rapid, experience-induced enhancement in odorant discrimination by anterior piriform cortex neurons. J Neurophysiol. 90:65-72.
29. Wiltrout C, Dogra S, Linster C. 2003. Configurational and nonconfigurational interactions between odorants in binary mixtures. Behav Neurosci. 117:236-245.
30. Zou Z, Buck LB. 2006. Combinatorial effects of odorant mixes in olfactory cortex. Science. 311:1477-1481.