-
1
-
-
14944385553
-
Global cancer statistics, 2002
-
Parkin DM, Bray F, Ferlay J, et al. Global cancer statistics, 2002. CA Cancer J Clin 2005; 55: 74-108
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 74-108
-
-
Parkin, D.M.1
Bray, F.2
Ferlay, J.3
-
2
-
-
33846894160
-
-
Parker D, Whelan SL, Ferlay J, et al. Cancer incidence in five continents. 143. Cancer IAfRo (editor). Lyon: IARC scientific publications, 1997
-
Parker D, Whelan SL, Ferlay J, et al. Cancer incidence in five continents. Vol. 143. Cancer IAfRo (editor). Lyon: IARC scientific publications, 1997
-
-
-
-
3
-
-
0036157392
-
Cancer statistics, 2002
-
Jemal A, Thomas A, Murray T, et al. Cancer statistics, 2002. CA Cancer J Clin 2002; 52: 23-47
-
(2002)
CA Cancer J Clin
, vol.52
, pp. 23-47
-
-
Jemal, A.1
Thomas, A.2
Murray, T.3
-
4
-
-
0038166882
-
-
Jablons DM, Cheng SJ, Carolyn Clary-Macy RN, et al. 1st International Lung Cancer Conference in Beijing, October 27-30, 2002. Lung Cancer 2003; 41: 237-44
-
Jablons DM, Cheng SJ, Carolyn Clary-Macy RN, et al. 1st International Lung Cancer Conference in Beijing, October 27-30, 2002. Lung Cancer 2003; 41: 237-44
-
-
-
-
6
-
-
33644530674
-
Taxanes as first-line therapy for advanced non-small cell lung cancer: A systematic review and practice guideline
-
Chu Q, Vincent M, Logan D, et al. Taxanes as first-line therapy for advanced non-small cell lung cancer: a systematic review and practice guideline. Lung Cancer 2005; 50: 355-74
-
(2005)
Lung Cancer
, vol.50
, pp. 355-374
-
-
Chu, Q.1
Vincent, M.2
Logan, D.3
-
7
-
-
5444235920
-
Meta-analysis of randomized clinical trials comparing cisplatin to carboplatin in patients with advanced non-small-cell lung cancer
-
Hotta K, Matsuo K, Ueoka H, et al. Meta-analysis of randomized clinical trials comparing cisplatin to carboplatin in patients with advanced non-small-cell lung cancer. J Clin Oncol 2004; 22: 3852-9
-
(2004)
J Clin Oncol
, vol.22
, pp. 3852-3859
-
-
Hotta, K.1
Matsuo, K.2
Ueoka, H.3
-
8
-
-
0028847005
-
Gemcitabine in the treatment of non-small-cell lung cancer
-
Burkes RL, Shepherd FA. Gemcitabine in the treatment of non-small-cell lung cancer. Ann Oncol 1995; 6 Suppl. 3: S57-60
-
(1995)
Ann Oncol
, vol.6
, Issue.SUPPL. 3
-
-
Burkes, R.L.1
Shepherd, F.A.2
-
9
-
-
0025978216
-
A phase I clinical, plasma, and cellular pharmacology study of gemcitabine
-
Abbruzzese JL, Grunewald R, Weeks EA, et al. A phase I clinical, plasma, and cellular pharmacology study of gemcitabine. J Clin Oncol 1991; 9: 491-8
-
(1991)
J Clin Oncol
, vol.9
, pp. 491-498
-
-
Abbruzzese, J.L.1
Grunewald, R.2
Weeks, E.A.3
-
10
-
-
0027946936
-
Weekly gemcitabine in advanced or metastatic solid tumors: A clinical phase I study
-
Pollera CF, Ceribelli A, Crecco M, et al. Weekly gemcitabine in advanced or metastatic solid tumors: a clinical phase I study. Invest New Drugs 1994; 12: 111-9
-
(1994)
Invest New Drugs
, vol.12
, pp. 111-119
-
-
Pollera, C.F.1
Ceribelli, A.2
Crecco, M.3
-
11
-
-
0033386066
-
Results of an independent oncology review board of pivotal clinical trials of gemcitabine in non-small cell lung cancer
-
Gwyther SJ, Aapro MS, Hatty SR, et al. Results of an independent oncology review board of pivotal clinical trials of gemcitabine in non-small cell lung cancer. Anticancer Drugs 1999; 10: 693-8
-
(1999)
Anticancer Drugs
, vol.10
, pp. 693-698
-
-
Gwyther, S.J.1
Aapro, M.S.2
Hatty, S.R.3
-
12
-
-
0033913982
-
Gemcitabine plus best supportive care (BSC) vs BSC in inoperable non-small cell lung cancer: A randomized trial with quality of life as the primary outcome. UK NSCLC Gemcitabine Group. Non-Small Cell Lung Cancer
-
Anderson H, Hopwood P, Stephens RJ, et al. Gemcitabine plus best supportive care (BSC) vs BSC in inoperable non-small cell lung cancer: a randomized trial with quality of life as the primary outcome. UK NSCLC Gemcitabine Group. Non-Small Cell Lung Cancer. Br J Cancer 2000; 83: 447-53
-
(2000)
Br J Cancer
, vol.83
, pp. 447-453
-
-
Anderson, H.1
Hopwood, P.2
Stephens, R.J.3
-
13
-
-
0037420202
-
Chemotherapy for elderly patients with advanced non-small-cell lung cancer: The Multicenter Italian Lung Cancer in the Elderly Study (MILES) phase III randomized trial
-
Gridelli C, Perrone F, Gallo C, et al. Chemotherapy for elderly patients with advanced non-small-cell lung cancer: the Multicenter Italian Lung Cancer in the Elderly Study (MILES) phase III randomized trial. J Natl Cancer Inst 2003; 95: 362-72
-
(2003)
J Natl Cancer Inst
, vol.95
, pp. 362-372
-
-
Gridelli, C.1
Perrone, F.2
Gallo, C.3
-
14
-
-
33644684204
-
Phase III trial of gemcitabine plus carboplatin versus single-agent gemcitabine in the treatment of locally advanced or metastatic non-small-cell lung cancer: The Swedish Lung Cancer Study Group
-
Sederholm C, Hillerdal G, Lamberg K, et al. Phase III trial of gemcitabine plus carboplatin versus single-agent gemcitabine in the treatment of locally advanced or metastatic non-small-cell lung cancer: the Swedish Lung Cancer Study Group. J Clin Oncol 2005; 23: 8380-8
-
(2005)
J Clin Oncol
, vol.23
, pp. 8380-8388
-
-
Sederholm, C.1
Hillerdal, G.2
Lamberg, K.3
-
15
-
-
0034772091
-
Clinical-benefit response in advanced non-small-cell lung cancer: A multicentre prospective randomized phase III study of single agent gemcitabine versus cisplatin-vindesine
-
Vansteenkiste JF, Vandebroek JE, Nackaerts KL, et al. Clinical-benefit response in advanced non-small-cell lung cancer: a multicentre prospective randomized phase III study of single agent gemcitabine versus cisplatin-vindesine. Ann Oncol 2001; 12: 1221-30
-
(2001)
Ann Oncol
, vol.12
, pp. 1221-1230
-
-
Vansteenkiste, J.F.1
Vandebroek, J.E.2
Nackaerts, K.L.3
-
16
-
-
0141799986
-
Cisplatin plus gemcitabine versus a cisplatin-based triplet versus nonplatinum sequential doublets in advanced non-small-cell lung cancer: A Spanish Lung Cancer Group phase III randomized trial
-
Alberola V, Camps C, Provencio M, et al. Cisplatin plus gemcitabine versus a cisplatin-based triplet versus nonplatinum sequential doublets in advanced non-small-cell lung cancer: a Spanish Lung Cancer Group phase III randomized trial. J Clin Oncol 2003; 21: 3207-13
-
(2003)
J Clin Oncol
, vol.21
, pp. 3207-3213
-
-
Alberola, V.1
Camps, C.2
Provencio, M.3
-
17
-
-
0345148774
-
Randomized phase III study of gemcitabine-cisplatin versus etoposide-cisplatin in the treatment of locally advanced or metastatic non-small-cell lung cancer
-
Cardenal F, Lopez-Cabrerizo MP, Anton A, et al. Randomized phase III study of gemcitabine-cisplatin versus etoposide-cisplatin in the treatment of locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol 1999; 17: 12-8
-
(1999)
J Clin Oncol
, vol.17
, pp. 12-18
-
-
Cardenal, F.1
Lopez-Cabrerizo, M.P.2
Anton, A.3
-
18
-
-
0034076846
-
Randomized trial comparing cisplatin, gemcitabine, and vinorelbine with either cisplatin and gemcitabine or cisplatin and vinorelbine in advanced non-small-cell lung cancer: Interim analysis of a phase III trial of the Southern Italy Cooperative Oncology Group
-
Comella P, Frasci G, Panza N, et al. Randomized trial comparing cisplatin, gemcitabine, and vinorelbine with either cisplatin and gemcitabine or cisplatin and vinorelbine in advanced non-small-cell lung cancer: interim analysis of a phase III trial of the Southern Italy Cooperative Oncology Group. J Clin Oncol 2000; 18: 1451-7
-
(2000)
J Clin Oncol
, vol.18
, pp. 1451-1457
-
-
Comella, P.1
Frasci, G.2
Panza, N.3
-
19
-
-
0032701095
-
Gemcitabine and cisplatin versus mitomycin, ifosfamide, and cisplatin in advanced non-small-cell lung cancer: A randomized phase III study of the Italian Lung Cancer Project
-
Crino L, Scagliotti GV, Ricci S, et al. Gemcitabine and cisplatin versus mitomycin, ifosfamide, and cisplatin in advanced non-small-cell lung cancer: a randomized phase III study of the Italian Lung Cancer Project. J Clin Oncol 1999; 17: 3522-30
-
(1999)
J Clin Oncol
, vol.17
, pp. 3522-3530
-
-
Crino, L.1
Scagliotti, G.V.2
Ricci, S.3
-
20
-
-
0037312019
-
Gemcitabine and cisplatin versus vinorelbine and cisplatin versus ifosfamide+gemcitabine followed by vinorelbine and cisplatin versus vinorelbine and cisplatin followed by ifosfamide and gemcitabine in stage IIIB-IV non small cell lung carcinoma: A prospective randomized phase III trial of the Gruppo Oncologico Italia Meridionale
-
Gebbia V, Galetta D, Caruso M, et al. Gemcitabine and cisplatin versus vinorelbine and cisplatin versus ifosfamide+gemcitabine followed by vinorelbine and cisplatin versus vinorelbine and cisplatin followed by ifosfamide and gemcitabine in stage IIIB-IV non small cell lung carcinoma: a prospective randomized phase III trial of the Gruppo Oncologico Italia Meridionale. Lung Cancer 2003; 39: 179-89
-
(2003)
Lung Cancer
, vol.39
, pp. 179-189
-
-
Gebbia, V.1
Galetta, D.2
Caruso, M.3
-
21
-
-
19944413630
-
Multicentre randomized phase III study comparing the same dose and schedule of cisplatin plus the same schedule of vinorelbine or gemcitabine in advanced non-small cell lung cancer
-
Martoni A, Marino A, Sperandi F, et al. Multicentre randomized phase III study comparing the same dose and schedule of cisplatin plus the same schedule of vinorelbine or gemcitabine in advanced non-small cell lung cancer. Eur J Cancer 2005; 41: 81-92
-
(2005)
Eur J Cancer
, vol.41
, pp. 81-92
-
-
Martoni, A.1
Marino, A.2
Sperandi, F.3
-
22
-
-
17344384668
-
Phase III trial of gemcitabine plus cisplatin versus cisplatin alone in patients with locally advanced or metastatic non-small-cell lung cancer
-
Sandler AB, Nemunaitis J, Denham C, et al. Phase III trial of gemcitabine plus cisplatin versus cisplatin alone in patients with locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol 2000; 18: 122-30
-
(2000)
J Clin Oncol
, vol.18
, pp. 122-130
-
-
Sandler, A.B.1
Nemunaitis, J.2
Denham, C.3
-
23
-
-
0036843105
-
Phase III randomized trial comparing three platinum-based doublets in advanced non-small-cell lung cancer
-
Scagliotti GV, De Marinis F, Rinaldi M, et al. Phase III randomized trial comparing three platinum-based doublets in advanced non-small-cell lung cancer. J Clin Oncol 2002; 20: 4285-91
-
(2002)
J Clin Oncol
, vol.20
, pp. 4285-4291
-
-
Scagliotti, G.V.1
De Marinis, F.2
Rinaldi, M.3
-
24
-
-
0037050352
-
Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
-
Schiller JH, Harrington D, Belani CP, et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med 2002; 346: 92-8
-
(2002)
N Engl J Med
, vol.346
, pp. 92-98
-
-
Schiller, J.H.1
Harrington, D.2
Belani, C.P.3
-
25
-
-
0346560025
-
Three-arm randomized study of two cisplatin-based regimens and paclitaxel plus gemcitabine in advanced non-small-cell lung cancer: A phase III trial of the European Organization for Research and Treatment of Cancer Lung Cancer Group: EORTC 08975
-
Smit EF, van Meerbeeck JP, Lianes P, et al. Three-arm randomized study of two cisplatin-based regimens and paclitaxel plus gemcitabine in advanced non-small-cell lung cancer: a phase III trial of the European Organization for Research and Treatment of Cancer Lung Cancer Group: EORTC 08975. J Clin Oncol 2003; 21: 3909-17
-
(2003)
J Clin Oncol
, vol.21
, pp. 3909-3917
-
-
Smit, E.F.1
van Meerbeeck, J.P.2
Lianes, P.3
-
26
-
-
0242361194
-
First-line gemcitabine with cisplatin or epirubicin in advanced non-small-cell lung cancer: A phase III trial
-
Wachters FM, Van Putten JW, Kramer H, et al. First-line gemcitabine with cisplatin or epirubicin in advanced non-small-cell lung cancer: a phase III trial. Br J Cancer 2003; 89: 1192-9
-
(2003)
Br J Cancer
, vol.89
, pp. 1192-1199
-
-
Wachters, F.M.1
Van Putten, J.W.2
Kramer, H.3
-
27
-
-
0042661285
-
Gemcitabine plus cisplatin vs gemcitabine plus carboplatin in stage IIIb and IV non-small cell lung cancer: A phase III randomized trial
-
Zatloukal P, Petruzelka L, Zemanova M, et al. Gemcitabine plus cisplatin vs gemcitabine plus carboplatin in stage IIIb and IV non-small cell lung cancer: a phase III randomized trial. Lung Cancer 2003; 41: 321-31
-
(2003)
Lung Cancer
, vol.41
, pp. 321-331
-
-
Zatloukal, P.1
Petruzelka, L.2
Zemanova, M.3
-
28
-
-
0037623677
-
Phase III trial of gemcitabine and carboplatin versus mitomycin, ifosfamide, and cisplatin or mitomycin, vinblastine, and cisplatin in patients with advanced nonsmall cell lung carcinoma
-
Danson S, Middleton MR, O'Byrne KJ, et al. Phase III trial of gemcitabine and carboplatin versus mitomycin, ifosfamide, and cisplatin or mitomycin, vinblastine, and cisplatin in patients with advanced nonsmall cell lung carcinoma. Cancer 2003; 98: 542-53
-
(2003)
Cancer
, vol.98
, pp. 542-553
-
-
Danson, S.1
Middleton, M.R.2
O'Byrne, K.J.3
-
29
-
-
0035985180
-
Gemcitabine (GEM) and carboplatin (CBDCA) versus cisplatin (CDDP) and vinblastine (VLB) in advanced non-small-cell lung cancer (NSCLC) stages III and IV: A phase III randomized trial
-
Grigorescu AC, Draghici IN, Nitipir C, et al. Gemcitabine (GEM) and carboplatin (CBDCA) versus cisplatin (CDDP) and vinblastine (VLB) in advanced non-small-cell lung cancer (NSCLC) stages III and IV: a phase III randomized trial. Lung Cancer 2002; 37: 9-14
-
(2002)
Lung Cancer
, vol.37
, pp. 9-14
-
-
Grigorescu, A.C.1
Draghici, I.N.2
Nitipir, C.3
-
30
-
-
16644398719
-
Gemcitabine plus carboplatin versus mitomycin, ifosfamide, and cisplatin in patients with stage IIIB or IV non-small-cell lung cancer: A phase III randomized study of the London Lung Cancer Group
-
Rudd RM, Gower NH, Spiro SG, et al. Gemcitabine plus carboplatin versus mitomycin, ifosfamide, and cisplatin in patients with stage IIIB or IV non-small-cell lung cancer: a phase III randomized study of the London Lung Cancer Group. J Clin Oncol 2005; 23: 142-53
-
(2005)
J Clin Oncol
, vol.23
, pp. 142-153
-
-
Rudd, R.M.1
Gower, N.H.2
Spiro, S.G.3
-
31
-
-
0035195433
-
Gemcitabine plus vinorelbine yields better survival outcome than vinorelbine alone in elderly patients with advanced non-small cell lung cancer: A Southern Italy Cooperative Oncology Group (SICOG) phase III trial
-
Frasci G, Lorusso V, Panza N, et al. Gemcitabine plus vinorelbine yields better survival outcome than vinorelbine alone in elderly patients with advanced non-small cell lung cancer: a Southern Italy Cooperative Oncology Group (SICOG) phase III trial. Lung Cancer 2001; 34 Suppl. 4: S65-9
-
(2001)
Lung Cancer
, vol.34
, Issue.SUPPL. 4
-
-
Frasci, G.1
Lorusso, V.2
Panza, N.3
-
32
-
-
21144437547
-
Vinorelbine plus cisplatin versus docetaxel plus gemcitabine in advanced non-small-cell lung cancer: A phase III randomized trial
-
Georgoulias V, Ardavanis A, Tsiafaki X, et al. Vinorelbine plus cisplatin versus docetaxel plus gemcitabine in advanced non-small-cell lung cancer: a phase III randomized trial. J Clin Oncol 2005; 23: 2937-45
-
(2005)
J Clin Oncol
, vol.23
, pp. 2937-2945
-
-
Georgoulias, V.1
Ardavanis, A.2
Tsiafaki, X.3
-
33
-
-
0041912766
-
Gemcitabine plus vinorelbine compared with cisplatin plus vinorelbine or cisplatin plus gemcitabine for advanced non-small-cell lung cancer: A phase III trial of the Italian GEMVIN Investigators and the National Cancer Institute of Canada Clinical Trials Group
-
Gridelli C, Gallo C, Shepherd FA, et al. Gemcitabine plus vinorelbine compared with cisplatin plus vinorelbine or cisplatin plus gemcitabine for advanced non-small-cell lung cancer: a phase III trial of the Italian GEMVIN Investigators and the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol 2003; 21: 3025-34
-
(2003)
J Clin Oncol
, vol.21
, pp. 3025-3034
-
-
Gridelli, C.1
Gallo, C.2
Shepherd, F.A.3
-
34
-
-
0036729263
-
Paclitaxel plus carboplatin versus gemcitabine plus paclitaxel in advanced non-small-cell lung cancer: A phase III randomized trial
-
Kosmidis P, Mylonakis N, Nicolaides C, et al. Paclitaxel plus carboplatin versus gemcitabine plus paclitaxel in advanced non-small-cell lung cancer: a phase III randomized trial. J Clin Oncol 2002; 20: 3578-85
-
(2002)
J Clin Oncol
, vol.20
, pp. 3578-3585
-
-
Kosmidis, P.1
Mylonakis, N.2
Nicolaides, C.3
-
35
-
-
2942731677
-
Randomized phase III study of gemcitabine and vinorelbine versus gemcitabine, vinorelbine, and cisplatin in the treatment of advanced non-small-cell lung cancer: From the German and Swiss Lung Cancer Study Group
-
Laack E, Dickgreber N, Muller T, et al. Randomized phase III study of gemcitabine and vinorelbine versus gemcitabine, vinorelbine, and cisplatin in the treatment of advanced non-small-cell lung cancer: from the German and Swiss Lung Cancer Study Group. J Clin Oncol 2004; 22: 2348-56
-
(2004)
J Clin Oncol
, vol.22
, pp. 2348-2356
-
-
Laack, E.1
Dickgreber, N.2
Muller, T.3
-
36
-
-
20944436114
-
Gemcitabine-docetaxel versus cisplatin-vinorelbine in advanced or metastatic non-small-cell lung cancer: A phase III study addressing the case for cisplatin
-
Pujol JL, Breton JL, Gervais R, et al. Gemcitabine-docetaxel versus cisplatin-vinorelbine in advanced or metastatic non-small-cell lung cancer: a phase III study addressing the case for cisplatin. Ann Oncol 2005; 16: 602-10
-
(2005)
Ann Oncol
, vol.16
, pp. 602-610
-
-
Pujol, J.L.1
Breton, J.L.2
Gervais, R.3
-
37
-
-
0035990063
-
A three-arm phase III randomized trial comparing combinations of platinum derivatives, ifosfamide and/or gemcitabine in stage IV non-small-cell lung cancer
-
Sculier JP, Lafitte JJ, Lecomte J, et al. A three-arm phase III randomized trial comparing combinations of platinum derivatives, ifosfamide and/or gemcitabine in stage IV non-small-cell lung cancer. Ann Oncol 2002; 13: 874-82
-
(2002)
Ann Oncol
, vol.13
, pp. 874-882
-
-
Sculier, J.P.1
Lafitte, J.J.2
Lecomte, J.3
-
38
-
-
10444237218
-
Efficacy of gemcitabine plus platinum chemotherapy compared with other platinum containing regimens in advanced non-small-cell lung cancer: A meta-analysis of survival outcomes
-
Le Chevalier T, Scagliotti G, Natale R, et al. Efficacy of gemcitabine plus platinum chemotherapy compared with other platinum containing regimens in advanced non-small-cell lung cancer: a meta-analysis of survival outcomes. Lung Cancer 2005; 47: 69-80
-
(2005)
Lung Cancer
, vol.47
, pp. 69-80
-
-
Le Chevalier, T.1
Scagliotti, G.2
Natale, R.3
-
39
-
-
0042967714
-
Targeted therapy in combination with gemcitabine in non-small cell lung cancer
-
Aug;
-
Rosell R, Crino L, Danenberg K, et al. Targeted therapy in combination with gemcitabine in non-small cell lung cancer. Semin Oncol 2003 Aug; 30 (4 Suppl. 10): 19-25
-
(2003)
Semin Oncol
, vol.30
, Issue.4 SUPPL. 10
, pp. 19-25
-
-
Rosell, R.1
Crino, L.2
Danenberg, K.3
-
40
-
-
13744265601
-
Modified weekly regimen with vinorelbine as a single agent in unresectable non-small cell lung cancer
-
Carrato A, Rosell R, Camps C, et al. Modified weekly regimen with vinorelbine as a single agent in unresectable non-small cell lung cancer. Lung Cancer 1997; 17: 261-9
-
(1997)
Lung Cancer
, vol.17
, pp. 261-269
-
-
Carrato, A.1
Rosell, R.2
Camps, C.3
-
41
-
-
0028595915
-
A phase II study of vinorelbine, a new derivative of vinca alkaloid, for previously untreated advanced non-small cell lung cancer
-
Furuse K, Kubota K, Kawahara M, et al. A phase II study of vinorelbine, a new derivative of vinca alkaloid, for previously untreated advanced non-small cell lung cancer. Japan Vinorelbine Lung Cancer Study Group. Lung Cancer 1994; 11: 385-91
-
(1994)
Japan Vinorelbine Lung Cancer Study Group. Lung Cancer
, vol.11
, pp. 385-391
-
-
Furuse, K.1
Kubota, K.2
Kawahara, M.3
-
42
-
-
0031105526
-
Vinorelbine is well tolerated and active in the treatment of elderly patients with advanced non-small cell lung cancer: A two-stage phase II study
-
Gridelli C, Perrone F, Gallo C, et al. Vinorelbine is well tolerated and active in the treatment of elderly patients with advanced non-small cell lung cancer: a two-stage phase II study. Eur J Cancer 1997; 33: 392-7
-
(1997)
Eur J Cancer
, vol.33
, pp. 392-397
-
-
Gridelli, C.1
Perrone, F.2
Gallo, C.3
-
43
-
-
0001179973
-
Vinorelbine treatment of advanced non-small cell lung cancer with special emphasis on elderly patients
-
Veronesi A, Crivellari D, Magri MD, et al. Vinorelbine treatment of advanced non-small cell lung cancer with special emphasis on elderly patients. Eur J Cancer 1996; 32A: 1809-11
-
(1996)
Eur J Cancer
, vol.32 A
, pp. 1809-1811
-
-
Veronesi, A.1
Crivellari, D.2
Magri, M.D.3
-
44
-
-
0035130402
-
The ELVIS trial: A phase III study of single-agent vinorelbine as first-line treatment in elderly patients with advanced non-small cell lung cancer. Elderly Lung Cancer Vinorelbine Italian Study
-
Gridelli C. The ELVIS trial: a phase III study of single-agent vinorelbine as first-line treatment in elderly patients with advanced non-small cell lung cancer. Elderly Lung Cancer Vinorelbine Italian Study. Oncologist 2001; 6 Suppl. 1: 4-7
-
(2001)
Oncologist
, vol.6
, Issue.SUPPL. 1
, pp. 4-7
-
-
Gridelli, C.1
-
45
-
-
10144246570
-
Randomized trial of vinorelbine compared with fluorouracil plus leucovorin in patients with stage IV non-small-cell lung cancer
-
Crawford J, O'Rourke M, Schiller JH, et al. Randomized trial of vinorelbine compared with fluorouracil plus leucovorin in patients with stage IV non-small-cell lung cancer. J Clin Oncol 1996; 14: 2774-84
-
(1996)
J Clin Oncol
, vol.14
, pp. 2774-2784
-
-
Crawford, J.1
O'Rourke, M.2
Schiller, J.H.3
-
46
-
-
0035686492
-
Oral vinorelbine pharmacokinetics and absolute bioavailability study in patients with solid tumors
-
Marty M, Fumoleau P, Adenis A, et al. Oral vinorelbine pharmacokinetics and absolute bioavailability study in patients with solid tumors. Ann Oncol 2001; 12: 1643-9
-
(2001)
Ann Oncol
, vol.12
, pp. 1643-1649
-
-
Marty, M.1
Fumoleau, P.2
Adenis, A.3
-
47
-
-
24344436463
-
Oral versus intravenous vinorelbine: Clinical safety profile
-
Gebbia V, Puozzo C. Oral versus intravenous vinorelbine: clinical safety profile. Expert Opin Drug Saf 2005; 4: 915-28
-
(2005)
Expert Opin Drug Saf
, vol.4
, pp. 915-928
-
-
Gebbia, V.1
Puozzo, C.2
-
48
-
-
0035191943
-
A multicenter randomized phase II study of oral vs intravenous vinorelbine in advanced non-small-cell lung cancer patients
-
Jassem J, Ramlau R, Karnicka-Mlodkowska H, et al. A multicenter randomized phase II study of oral vs intravenous vinorelbine in advanced non-small-cell lung cancer patients. Ann Oncol 2001; 12: 1375-81
-
(2001)
Ann Oncol
, vol.12
, pp. 1375-1381
-
-
Jassem, J.1
Ramlau, R.2
Karnicka-Mlodkowska, H.3
-
49
-
-
10744231401
-
Oral vinorelbine for the treatment of metastatic non-small cell lung cancer in elderly patients: A phase II trial of efficacy and toxicity
-
Kanard A, Jatoi A, Castillo R, et al. Oral vinorelbine for the treatment of metastatic non-small cell lung cancer in elderly patients: a phase II trial of efficacy and toxicity. Lung Cancer 2004; 43: 345-53
-
(2004)
Lung Cancer
, vol.43
, pp. 345-353
-
-
Kanard, A.1
Jatoi, A.2
Castillo, R.3
-
50
-
-
7044240643
-
Oral vinorelbine given as monotherapy to advanced, elderly NSCLC patients: A multicentre phase II trial
-
Gridelli C, Manegold C, Mali P, et al. Oral vinorelbine given as monotherapy to advanced, elderly NSCLC patients: a multicentre phase II trial. Eur J Cancer 2004; 40: 2424-31
-
(2004)
Eur J Cancer
, vol.40
, pp. 2424-2431
-
-
Gridelli, C.1
Manegold, C.2
Mali, P.3
-
51
-
-
20144379661
-
Phase II trial of oral vinorelbine in combination with cisplatin followed by consolidation therapy with oral vinorelbine in advanced NSCLC
-
Lena MD, Ramlau R, Hansen O, et al. Phase II trial of oral vinorelbine in combination with cisplatin followed by consolidation therapy with oral vinorelbine in advanced NSCLC. Lung Cancer 2005; 48: 129-35
-
(2005)
Lung Cancer
, vol.48
, pp. 129-135
-
-
Lena, M.D.1
Ramlau, R.2
Hansen, O.3
-
52
-
-
0027952504
-
Vinorelbine versus vinorelbine plus cisplatin in advanced non-small cell lung cancer: A randomized trial
-
Depierre A, Chastang C, Quoix E, et al. Vinorelbine versus vinorelbine plus cisplatin in advanced non-small cell lung cancer: a randomized trial. Ann Oncol 1994; 5: 37-42
-
(1994)
Ann Oncol
, vol.5
, pp. 37-42
-
-
Depierre, A.1
Chastang, C.2
Quoix, E.3
-
53
-
-
0028154069
-
Randomized study of vinorelbine and cisplatin versus vindesine and cisplatin versus vinorelbine alone in advanced non-small-cell lung cancer: Results of a European multicenter trial including 612 patients
-
Le Chevalier T, Brisgand D, Douillard JY, et al. Randomized study of vinorelbine and cisplatin versus vindesine and cisplatin versus vinorelbine alone in advanced non-small-cell lung cancer: results of a European multicenter trial including 612 patients. J Clin Oncol 1994; 12: 360-7
-
(1994)
J Clin Oncol
, vol.12
, pp. 360-367
-
-
Le Chevalier, T.1
Brisgand, D.2
Douillard, J.Y.3
-
54
-
-
0031861215
-
Randomized trial comparing cisplatin with cisplatin plus vinorelbine in the treatment of advanced non-small-cell lung cancer: A Southwest Oncology Group study
-
Wozniak AJ, Crowley JJ, Balcerzak SP, et al. Randomized trial comparing cisplatin with cisplatin plus vinorelbine in the treatment of advanced non-small-cell lung cancer: a Southwest Oncology Group study. J Clin Oncol 1998; 16: 2459-65
-
(1998)
J Clin Oncol
, vol.16
, pp. 2459-2465
-
-
Wozniak, A.J.1
Crowley, J.J.2
Balcerzak, S.P.3
-
55
-
-
0035126551
-
Long term analysis of survival in the European randomized trial comparing vinorelbine/cisplatin to vindesine/cisplatin and vinorelbine alone in advanced non-small cell lung cancer
-
Le Chevalier T, Brisgand D, Soria JC, et al. Long term analysis of survival in the European randomized trial comparing vinorelbine/cisplatin to vindesine/cisplatin and vinorelbine alone in advanced non-small cell lung cancer. Oncologist 2001; 6 Suppl. 1: 8-11
-
(2001)
Oncologist
, vol.6
, Issue.SUPPL. 1
, pp. 8-11
-
-
Le Chevalier, T.1
Brisgand, D.2
Soria, J.C.3
-
56
-
-
9844229899
-
Cisplatin and vinorelbine followed by ifosfamide plus epirubicin vs the opposite sequence in advanced unresectable stage III and metastatic stage IV non-small-cell lung cancer: A prospective randomized study of the Southern Italy Oncology Group (GOIM)
-
Colucci G, Gebbia V, Galetta D, et al. Cisplatin and vinorelbine followed by ifosfamide plus epirubicin vs the opposite sequence in advanced unresectable stage III and metastatic stage IV non-small-cell lung cancer: a prospective randomized study of the Southern Italy Oncology Group (GOIM). Br J Cancer 1997; 76: 1509-17
-
(1997)
Br J Cancer
, vol.76
, pp. 1509-1517
-
-
Colucci, G.1
Gebbia, V.2
Galetta, D.3
-
57
-
-
0042413836
-
Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small-cell lung cancer: The TAX 326 study group
-
Fossella F, Pereira JR, von Pawel J, et al. Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small-cell lung cancer: the TAX 326 study group. J Clin Oncol 2003; 21: 3016-24
-
(2003)
J Clin Oncol
, vol.21
, pp. 3016-3024
-
-
Fossella, F.1
Pereira, J.R.2
von Pawel, J.3
-
58
-
-
0036021714
-
Vinorelbine plus cisplatin versus cisplatin plus vindesine and mitomycin C in stage IIIB-IV non-small cell lung carcinoma: A prospective randomized study
-
Gebbia V, Galetta D, Riccardi F, et al. Vinorelbine plus cisplatin versus cisplatin plus vindesine and mitomycin C in stage IIIB-IV non-small cell lung carcinoma: a prospective randomized study. Lung Cancer 2002; 37: 179-87
-
(2002)
Lung Cancer
, vol.37
, pp. 179-187
-
-
Gebbia, V.1
Galetta, D.2
Riccardi, F.3
-
59
-
-
0035397994
-
Randomized phase III trial of paclitaxel plus carboplatin versus vinorelbine plus cisplatin in the treatment of patients with advanced non-small-cell lung cancer: A Southwest Oncology Group trial
-
Kelly K, Crowley J, Bunn Jr PA, et al. Randomized phase III trial of paclitaxel plus carboplatin versus vinorelbine plus cisplatin in the treatment of patients with advanced non-small-cell lung cancer: a Southwest Oncology Group trial. J Clin Oncol 2001; 19: 3210-8
-
(2001)
J Clin Oncol
, vol.19
, pp. 3210-3218
-
-
Kelly, K.1
Crowley, J.2
Bunn Jr, P.A.3
-
60
-
-
0032191525
-
Multicenter randomized clinical trial on high-dose epirubicin plus cis-platinum versus vinorelbine plus cis-platinum in advanced non small cell lung cancer
-
Martoni A, Guaraldi M, Piana E, et al. Multicenter randomized clinical trial on high-dose epirubicin plus cis-platinum versus vinorelbine plus cis-platinum in advanced non small cell lung cancer. Lung Cancer 1998; 22: 31-8
-
(1998)
Lung Cancer
, vol.22
, pp. 31-38
-
-
Martoni, A.1
Guaraldi, M.2
Piana, E.3
-
61
-
-
0036929352
-
GLOB-1: A prospective randomized clinical phase III trial comparing vinorelbine-cisplatin with vinorelbine-ifosfamide-cisplatin in metastatic non-small-cell lung cancer patients
-
Souquet PJ, Tan EH, Rodrigues Pereira J, et al. GLOB-1: a prospective randomized clinical phase III trial comparing vinorelbine-cisplatin with vinorelbine-ifosfamide-cisplatin in metastatic non-small-cell lung cancer patients. Ann Oncol 2002; 13: 1853-61
-
(2002)
Ann Oncol
, vol.13
, pp. 1853-1861
-
-
Souquet, P.J.1
Tan, E.H.2
Rodrigues Pereira, J.3
-
62
-
-
0035020048
-
Phase III trial of cisplatin/gemcitabine with or without vinorelbine or paclitaxel in advanced non-small cell lung cancer
-
Comella P. Phase III trial of cisplatin/gemcitabine with or without vinorelbine or paclitaxel in advanced non-small cell lung cancer. Semin Oncol 2001; 28: 7-10
-
(2001)
Semin Oncol
, vol.28
, pp. 7-10
-
-
Comella, P.1
-
63
-
-
2542510542
-
Multicenter randomized trial comparing cisplatin-mitomycin-vinorelbine versus cisplatin-mitomycin-vindesine in advanced non-small cell lung cancer. Groupe Francais de Pneumo-Cancerologie
-
Pérol M, Guerin JC, Thomas P, et al. Multicenter randomized trial comparing cisplatin-mitomycin-vinorelbine versus cisplatin-mitomycin-vindesine in advanced non-small cell lung cancer. Groupe Francais de Pneumo-Cancerologie. Lung Cancer 1996; 14: 119-34
-
(1996)
Lung Cancer
, vol.14
, pp. 119-134
-
-
Pérol, M.1
Guerin, J.C.2
Thomas, P.3
-
64
-
-
22044445819
-
Randomized study of vinorelbine: Gemcitabine versus vinorelbine: carboplatin in patients with advanced non-small cell lung cancer
-
Tan EH, Szczesna A, Krzakowski M, et al. Randomized study of vinorelbine: gemcitabine versus vinorelbine: carboplatin in patients with advanced non-small cell lung cancer. Lung Cancer 2005; 49: 233-40
-
(2005)
Lung Cancer
, vol.49
, pp. 233-240
-
-
Tan, E.H.1
Szczesna, A.2
Krzakowski, M.3
-
65
-
-
33846857018
-
A randomized comparison of carboplatin/vinorelbine versus carboplatin/gemcitabine in advanced non-small cell lung cancer (NSCLC) [abstract no. 7033]
-
Helbekkmo N, Sundstroem SH, Aaseboe U, et al. A randomized comparison of carboplatin/vinorelbine versus carboplatin/gemcitabine in advanced non-small cell lung cancer (NSCLC) [abstract no. 7033]. J Clin Oncol (Meeting Abstracts) 2006; 24: 7033
-
(2006)
J Clin Oncol (Meeting Abstracts)
, vol.24
, pp. 7033
-
-
Helbekkmo, N.1
Sundstroem, S.H.2
Aaseboe, U.3
-
66
-
-
4143145523
-
Gemcitabine with either paclitaxel or vinorelbine vs paclitaxel or gemcitabine alone for elderly or unfit advanced non-small-cell lung cancer patients
-
Comella P, Frasci G, Carnicelli P, et al. Gemcitabine with either paclitaxel or vinorelbine vs paclitaxel or gemcitabine alone for elderly or unfit advanced non-small-cell lung cancer patients. Br J Cancer 2004; 91: 489-97
-
(2004)
Br J Cancer
, vol.91
, pp. 489-497
-
-
Comella, P.1
Frasci, G.2
Carnicelli, P.3
-
67
-
-
0033932224
-
Gemcitabine plus vinorelbine versus vinorelbine alone in elderly patients with advanced non-small-cell lung cancer
-
Frasci G, Lorusso V, Panza N, et al. Gemcitabine plus vinorelbine versus vinorelbine alone in elderly patients with advanced non-small-cell lung cancer. J Clin Oncol 2000; 18: 2529-36
-
(2000)
J Clin Oncol
, vol.18
, pp. 2529-2536
-
-
Frasci, G.1
Lorusso, V.2
Panza, N.3
-
68
-
-
4143146439
-
Front-line paclitaxel-vinorelbine versus paclitaxel-carboplatin in patients with advanced non-small-cell lung cancer: A randomized phase III trial
-
Stathopoulos GP, Veslemes M, Georgatou N, et al. Front-line paclitaxel-vinorelbine versus paclitaxel-carboplatin in patients with advanced non-small-cell lung cancer: a randomized phase III trial. Ann Oncol 2004; 15: 1048-55
-
(2004)
Ann Oncol
, vol.15
, pp. 1048-1055
-
-
Stathopoulos, G.P.1
Veslemes, M.2
Georgatou, N.3
-
69
-
-
0034095853
-
Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens
-
Fossella FV, DeVore R, Kerr RN, et al. Randomized phase III trial of docetaxel versus vinorelbine or ifosfamide in patients with advanced non-small-cell lung cancer previously treated with platinum-containing chemotherapy regimens. J Clin Oncol 2000; 18: 2354-62
-
(2000)
J Clin Oncol
, vol.18
, pp. 2354-2362
-
-
Fossella, F.V.1
DeVore, R.2
Kerr, R.N.3
-
70
-
-
0028843552
-
Chemotherapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomized clinical trials
-
Non-Small Cell Lung Cancer Collaborative Group
-
Non-Small Cell Lung Cancer Collaborative Group. Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomized clinical trials. BMJ 1995; 311: 899-909
-
(1995)
BMJ
, vol.311
, pp. 899-909
-
-
-
71
-
-
0020062191
-
VP16-213 and podophyllotoxin: A study on the relationship between chemical structure and biological activity
-
Loike JD. VP16-213 and podophyllotoxin: a study on the relationship between chemical structure and biological activity. Cancer Chemother Pharmacol 1982; 7: 103-11
-
(1982)
Cancer Chemother Pharmacol
, vol.7
, pp. 103-111
-
-
Loike, J.D.1
-
72
-
-
0025313120
-
Etoposide versus etoposide plus high-dose cisplatin in the management of advanced non-small cell lung cancer: Results of a prospective randomized FONICAP trial. Italian Lung Cancer Task Force
-
Rosso R, Salvati F, Ardizzoni A, et al. Etoposide versus etoposide plus high-dose cisplatin in the management of advanced non-small cell lung cancer: results of a prospective randomized FONICAP trial. Italian Lung Cancer Task Force. Cancer 1990; 66: 130-4
-
(1990)
Cancer
, vol.66
, pp. 130-134
-
-
Rosso, R.1
Salvati, F.2
Ardizzoni, A.3
-
74
-
-
0026500785
-
Randomized study of cyclophosphamide, doxorubicin, and vincristine versus etoposide and cisplatin versus alternation of these two regimens in extensive small-cell lung cancer: A phase III trial of the Southeastern Cancer Study Group
-
Roth BJ, Johnson DH, Einhorn LH, et al. Randomized study of cyclophosphamide, doxorubicin, and vincristine versus etoposide and cisplatin versus alternation of these two regimens in extensive small-cell lung cancer: a phase III trial of the Southeastern Cancer Study Group. J Clin Oncol 1992; 10: 282-91
-
(1992)
J Clin Oncol
, vol.10
, pp. 282-291
-
-
Roth, B.J.1
Johnson, D.H.2
Einhorn, L.H.3
-
75
-
-
0025898914
-
Randomized trial of cyclophosphamide, doxorubicin, and vincristine versus cisplatin and etoposide versus alternation of these regimens in small-cell lung cancer
-
Fukuoka M, Furuse K, Saijo N, et al. Randomized trial of cyclophosphamide, doxorubicin, and vincristine versus cisplatin and etoposide versus alternation of these regimens in small-cell lung cancer. J Natl Cancer Inst 1991; 83: 855-61
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 855-861
-
-
Fukuoka, M.1
Furuse, K.2
Saijo, N.3
-
76
-
-
0020419172
-
Combination chemotherapy with cisplatin and etoposide in bronchogenic squamous cell carcinoma and adenocarcinoma: A study by the EORTC lung cancer working party (Belgium)
-
Longeval E, Klastersky J. Combination chemotherapy with cisplatin and etoposide in bronchogenic squamous cell carcinoma and adenocarcinoma: a study by the EORTC lung cancer working party (Belgium). Cancer 1982; 50: 2751-6
-
(1982)
Cancer
, vol.50
, pp. 2751-2756
-
-
Longeval, E.1
Klastersky, J.2
-
77
-
-
0030900495
-
Gemcitabine versus the combination of cisplatin and etoposide in patients with inoperable non-small-cell lung cancer in a phase II randomized study
-
Perng RP, Chen YM, Ming-Liu J, et al. Gemcitabine versus the combination of cisplatin and etoposide in patients with inoperable non-small-cell lung cancer in a phase II randomized study. J Clin Oncol 1997; 15: 2097-102
-
(1997)
J Clin Oncol
, vol.15
, pp. 2097-2102
-
-
Perng, R.P.1
Chen, Y.M.2
Ming-Liu, J.3
-
78
-
-
0033950286
-
Comparison of survival and quality of life in advanced non-small-cell lung cancer patients treated with two dose levels of paclitaxel combined with cisplatin versus etoposide with cisplatin: Results of an Eastern Cooperative Oncology Group trial
-
Bonomi P, Kim K, Fairclough D, et al. Comparison of survival and quality of life in advanced non-small-cell lung cancer patients treated with two dose levels of paclitaxel combined with cisplatin versus etoposide with cisplatin: results of an Eastern Cooperative Oncology Group trial. J Clin Oncol 2000; 18: 623-31
-
(2000)
J Clin Oncol
, vol.18
, pp. 623-631
-
-
Bonomi, P.1
Kim, K.2
Fairclough, D.3
-
79
-
-
25444511051
-
Randomized phase III trial comparing cisplatin-etoposide to carboplatin-paclitaxel in advanced or metastatic non-small cell lung cancer
-
Belani CP, Lee JS, Socinski MA, et al. Randomized phase III trial comparing cisplatin-etoposide to carboplatin-paclitaxel in advanced or metastatic non-small cell lung cancer. Ann Oncol 2005; 16: 1069-75
-
(2005)
Ann Oncol
, vol.16
, pp. 1069-1075
-
-
Belani, C.P.1
Lee, J.S.2
Socinski, M.A.3
-
80
-
-
0034255537
-
A phase II study of gemcitabine plus oral etoposide in the treatment of patients with advanced nonsmall cell lung carcinoma
-
Mok TS, Zee B, Chan AT, et al. A phase II study of gemcitabine plus oral etoposide in the treatment of patients with advanced nonsmall cell lung carcinoma. Cancer 2000; 89: 543-50
-
(2000)
Cancer
, vol.89
, pp. 543-550
-
-
Mok, T.S.1
Zee, B.2
Chan, A.T.3
-
81
-
-
23844548571
-
Phase II randomized study comparing the toxicity profile of gemcitabine plus cisplatin with gemcitabine plus oral etoposide in the treatment of advanced non-small cell lung cancer
-
Mok TS, Lam KC, Lee C, et al. Phase II randomized study comparing the toxicity profile of gemcitabine plus cisplatin with gemcitabine plus oral etoposide in the treatment of advanced non-small cell lung cancer. Oncology 2005; 68: 485-92
-
(2005)
Oncology
, vol.68
, pp. 485-492
-
-
Mok, T.S.1
Lam, K.C.2
Lee, C.3
-
82
-
-
0031782882
-
Superiority of sequential versus concurrent administration of paclitaxel with etoposide in advanced non-small cell lung cancer: Comparison of two phase II trials
-
Felip E, Massuti B, Camps C, et al. Superiority of sequential versus concurrent administration of paclitaxel with etoposide in advanced non-small cell lung cancer: comparison of two phase II trials. Clin Cancer Res 1998; 4: 2723-8
-
(1998)
Clin Cancer Res
, vol.4
, pp. 2723-2728
-
-
Felip, E.1
Massuti, B.2
Camps, C.3
-
83
-
-
9844220291
-
Phase I study of sequentially administered topoisomerase I inhibitor (irinotecan) and topoisomerase II inhibitor (etoposide) for metastatic non-small-cell lung cancer
-
Ando M, Eguchi K, Shinkai T, et al. Phase I study of sequentially administered topoisomerase I inhibitor (irinotecan) and topoisomerase II inhibitor (etoposide) for metastatic non-small-cell lung cancer. Br J Cancer 1997; 76: 1494-9
-
(1997)
Br J Cancer
, vol.76
, pp. 1494-1499
-
-
Ando, M.1
Eguchi, K.2
Shinkai, T.3
-
84
-
-
0037428773
-
Randomized phase III trial of irinotecan combined with cisplatin for advanced non-small-cell lung cancer
-
Negoro S, Masuda N, Takada Y, et al. Randomized phase III trial of irinotecan combined with cisplatin for advanced non-small-cell lung cancer. Br J Cancer 2003; 88: 335-41
-
(2003)
Br J Cancer
, vol.88
, pp. 335-341
-
-
Negoro, S.1
Masuda, N.2
Takada, Y.3
-
85
-
-
0032893109
-
Overview of MTA in the treatment of non-small cell lung cancer
-
Postmus P, Green MR. Overview of MTA in the treatment of non-small cell lung cancer. Semin Oncol 1999; 26: 31-6
-
(1999)
Semin Oncol
, vol.26
, pp. 31-36
-
-
Postmus, P.1
Green, M.R.2
-
86
-
-
15644372742
-
A phase I and pharmacokinetic study of LY231514, the multitargeted antifolate
-
McDonald A, Vasey PA, Adams L, et al. A phase I and pharmacokinetic study of LY231514, the multitargeted antifolate. Clin Cancer Res 1998; 4: 605-10
-
(1998)
Clin Cancer Res
, vol.4
, pp. 605-610
-
-
McDonald, A.1
Vasey, P.A.2
Adams, L.3
-
87
-
-
0028849683
-
Initial phase I evaluation of the novel thymidylate synthase inhibitor LY231514, using the modified continual reassessment method for dose escalation
-
Rinaldi D, Burris H, Dorr F, et al. Initial phase I evaluation of the novel thymidylate synthase inhibitor LY231514, using the modified continual reassessment method for dose escalation. J Clin Oncol 1995; 17: 2842-50
-
(1995)
J Clin Oncol
, vol.17
, pp. 2842-2850
-
-
Rinaldi, D.1
Burris, H.2
Dorr, F.3
-
88
-
-
0035423962
-
Phase II study of pemetrexed disodium, a multitargeted antifolate, and cisplatin as first-line therapy in patients with advanced nonsmall cell lung carcinoma: A study of the National Cancer Institute of Canada Clinical Trials Group
-
Shepherd FA, Dancey J, Arnold A, et al. Phase II study of pemetrexed disodium, a multitargeted antifolate, and cisplatin as first-line therapy in patients with advanced nonsmall cell lung carcinoma: a study of the National Cancer Institute of Canada Clinical Trials Group. Cancer 2001; 92: 595-600
-
(2001)
Cancer
, vol.92
, pp. 595-600
-
-
Shepherd, F.A.1
Dancey, J.2
Arnold, A.3
-
89
-
-
28044463139
-
Phase II study of pemetrexed in combination with carboplatin in the first-line treatment of advanced nonsmall cell lung cancer
-
Zinner RG, Fossella FV, Gladish GW, et al. Phase II study of pemetrexed in combination with carboplatin in the first-line treatment of advanced nonsmall cell lung cancer. Cancer 2005; 104: 2449-56
-
(2005)
Cancer
, vol.104
, pp. 2449-2456
-
-
Zinner, R.G.1
Fossella, F.V.2
Gladish, G.W.3
-
90
-
-
19944426696
-
Pemetrexed combined with oxaliplatin or carboplatin as first-line treatment in advanced non-small cell lung cancer: A multicenter, randomized, phase II trial
-
Scagliotti GV, Kortsik C, Dark GG, et al. Pemetrexed combined with oxaliplatin or carboplatin as first-line treatment in advanced non-small cell lung cancer: a multicenter, randomized, phase II trial. Clin Cancer Res 2005; 11: 690-6
-
(2005)
Clin Cancer Res
, vol.11
, pp. 690-696
-
-
Scagliotti, G.V.1
Kortsik, C.2
Dark, G.G.3
-
91
-
-
23744482948
-
A phase I/II study of pemetrexed and vinorelbine in patients with non-small cell lung cancer
-
Clarke SJ, Boyer MJ, Millward M, et al. A phase I/II study of pemetrexed and vinorelbine in patients with non-small cell lung cancer. Lung Cancer 2005; 49: 401-12
-
(2005)
Lung Cancer
, vol.49
, pp. 401-412
-
-
Clarke, S.J.1
Boyer, M.J.2
Millward, M.3
-
92
-
-
0036317531
-
Gemcitabine and pemetrexed (Alimta) in thoracic cancers: Present and future perspectives: introduction and current controversies
-
Le Chevalier T. Gemcitabine and pemetrexed (Alimta) in thoracic cancers: present and future perspectives: introduction and current controversies. Semin Oncol 2002; 29: 43-6
-
(2002)
Semin Oncol
, vol.29
, pp. 43-46
-
-
Le Chevalier, T.1
-
93
-
-
2442661845
-
Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy
-
Hanna N, Shepherd FA, Fossella FV, et al. Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy. J Clin Oncol 2004; 22: 1589-97
-
(2004)
J Clin Oncol
, vol.22
, pp. 1589-1597
-
-
Hanna, N.1
Shepherd, F.A.2
Fossella, F.V.3
-
94
-
-
4043181214
-
Cancer genes and the pathways they control
-
Vogelstein B, Kinzler KW. Cancer genes and the pathways they control. Nat Med 2004; 10: 789-99
-
(2004)
Nat Med
, vol.10
, pp. 789-799
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
95
-
-
0022468532
-
Expression of epidermal growth factor receptor (EGF-R) in human lung tumors
-
Cerny T, Barnes DM, Hasleton P, et al. Expression of epidermal growth factor receptor (EGF-R) in human lung tumors. Br J Cancer 1986; 54: 265-9
-
(1986)
Br J Cancer
, vol.54
, pp. 265-269
-
-
Cerny, T.1
Barnes, D.M.2
Hasleton, P.3
-
96
-
-
0030980781
-
Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor alpha is frequent in resectable non-small cell lung cancer but does not predict tumor progression
-
Rusch V, Klimstra D, Venkatraman E, et al. Overexpression of the epidermal growth factor receptor and its ligand transforming growth factor alpha is frequent in resectable non-small cell lung cancer but does not predict tumor progression. Clin Cancer Res 1997; 3: 515-22
-
(1997)
Clin Cancer Res
, vol.3
, pp. 515-522
-
-
Rusch, V.1
Klimstra, D.2
Venkatraman, E.3
-
97
-
-
0035170259
-
Anticancer therapy targeting the erbB family of receptor tyrosine kinases
-
Slichenmyer WJ, Fry DW. Anticancer therapy targeting the erbB family of receptor tyrosine kinases. Semin Oncol 2001; 28: 67-79
-
(2001)
Semin Oncol
, vol.28
, pp. 67-79
-
-
Slichenmyer, W.J.1
Fry, D.W.2
-
98
-
-
0031963988
-
Prognostic value of ERBB-1, VEGF, cyclin A, FOS, JUN and MYC in patients with squamous cell lung carcinomas
-
Volm M, Rittgen W, Drings P. Prognostic value of ERBB-1, VEGF, cyclin A, FOS, JUN and MYC in patients with squamous cell lung carcinomas. Br J Cancer 1998; 77: 663-9
-
(1998)
Br J Cancer
, vol.77
, pp. 663-669
-
-
Volm, M.1
Rittgen, W.2
Drings, P.3
-
99
-
-
33846783520
-
Randomized phase II study of cetuximab in combination with cisplatin (C) and vinorelbine (V) vs. CV alone in the first line treatment of patients with epidermal growth factor receptor (EGFR)-expressing advanced non small cell lung cancer (NSCLC) [abstract]
-
Rosell R, Daniel C, Ramlau R, et al. Randomized phase II study of cetuximab in combination with cisplatin (C) and vinorelbine (V) vs. CV alone in the first line treatment of patients with epidermal growth factor receptor (EGFR)-expressing advanced non small cell lung cancer (NSCLC) [abstract]. J Clin Oncol (Meeting Abstracts) 2004; 22: 7012
-
(2004)
J Clin Oncol (Meeting Abstracts)
, vol.22
, pp. 7012
-
-
Rosell, R.1
Daniel, C.2
Ramlau, R.3
-
100
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W, Miller V, Zakowski M, et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A 2004; 101: 13306-11
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
-
101
-
-
27244443759
-
Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: A Southwest Oncology Group Study
-
Hirsch FR, Varella-Garcia M, McCoy J, et al. Increased epidermal growth factor receptor gene copy number detected by fluorescence in situ hybridization associates with increased sensitivity to gefitinib in patients with bronchioloalveolar carcinoma subtypes: a Southwest Oncology Group Study. J Clin Oncol 2005; 23: 6838-45
-
(2005)
J Clin Oncol
, vol.23
, pp. 6838-6845
-
-
Hirsch, F.R.1
Varella-Garcia, M.2
McCoy, J.3
-
102
-
-
1542503746
-
Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: A phase III trial: INTACT 1
-
Giaccone G, Herbst RS, Manegold C, et al. Gefitinib in combination with gemcitabine and cisplatin in advanced non-small-cell lung cancer: a phase III trial: INTACT 1. J Clin Oncol 2004; 22: 777-84
-
(2004)
J Clin Oncol
, vol.22
, pp. 777-784
-
-
Giaccone, G.1
Herbst, R.S.2
Manegold, C.3
-
103
-
-
19844375720
-
Epidermal growth factor receptor mutations in non-small-cell lung cancer: Implications for treatment and tumor biology
-
Janne PA, Engelman JA, Johnson BE. Epidermal growth factor receptor mutations in non-small-cell lung cancer: implications for treatment and tumor biology. J Clin Oncol 2005; 23: 3227-34
-
(2005)
J Clin Oncol
, vol.23
, pp. 3227-3234
-
-
Janne, P.A.1
Engelman, J.A.2
Johnson, B.E.3
-
104
-
-
30344446398
-
Targeted therapy for the treatment of advanced non-small cell lung cancer: A review of the epidermal growth factor receptor antagonists
-
Silvestri GA, Rivera MP. Targeted therapy for the treatment of advanced non-small cell lung cancer: a review of the epidermal growth factor receptor antagonists. Chest 2005; 128: 3975-84
-
(2005)
Chest
, vol.128
, pp. 3975-3984
-
-
Silvestri, G.A.1
Rivera, M.P.2
-
105
-
-
1542713370
-
Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: A phase III trial: INTACT 2
-
Herbst RS, Giaccone G, Schiller JH, et al. Gefitinib in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: a phase III trial: INTACT 2. J Clin Oncol 2004; 22: 785-94
-
(2004)
J Clin Oncol
, vol.22
, pp. 785-794
-
-
Herbst, R.S.1
Giaccone, G.2
Schiller, J.H.3
-
106
-
-
24944440830
-
TRIBUTE: A phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer
-
Herbst RS, Prager D, Hermann R, et al. TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer. J Clin Oncol 2005; 23: 5892-9
-
(2005)
J Clin Oncol
, vol.23
, pp. 5892-5899
-
-
Herbst, R.S.1
Prager, D.2
Hermann, R.3
-
107
-
-
4444238981
-
Results of a phase III trial of erlotinib (OSI-774) combined with cisplatin and gemcitabine (GC) chemotherapy in advanced non-small cell lung cancer (NSCLC) [abstract no. 7010]
-
Gatzemeier U, Pluzanska A, Szczesna A, et al. Results of a phase III trial of erlotinib (OSI-774) combined with cisplatin and gemcitabine (GC) chemotherapy in advanced non-small cell lung cancer (NSCLC) [abstract no. 7010]. J Clin Oncol 2004; 22 (14 Suppl.): 617
-
(2004)
J Clin Oncol
, vol.22
, Issue.14 SUPPL.
, pp. 617
-
-
Gatzemeier, U.1
Pluzanska, A.2
Szczesna, A.3
-
108
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
Shepherd FA, Rodrigues Pereira J, Ciuleanu T, et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005; 353: 123-32
-
(2005)
N Engl J Med
, vol.353
, pp. 123-132
-
-
Shepherd, F.A.1
Rodrigues Pereira, J.2
Ciuleanu, T.3
-
109
-
-
19844362355
-
Epidermal growth factor receptor inhibitors in the treatment of non-small-cell lung cancer
-
Giaccone G. Epidermal growth factor receptor inhibitors in the treatment of non-small-cell lung cancer. J Clin Oncol 2005; 23: 3235-42
-
(2005)
J Clin Oncol
, vol.23
, pp. 3235-3242
-
-
Giaccone, G.1
-
110
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004; 304: 1497-500
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
111
-
-
2942657615
-
Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
-
Johnson DH, Fehrenbacher L, Novotny WF, et al. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol 2004; 22: 2184-91
-
(2004)
J Clin Oncol
, vol.22
, pp. 2184-2191
-
-
Johnson, D.H.1
Fehrenbacher, L.2
Novotny, W.F.3
-
112
-
-
33846887895
-
-
Sandler A, Gray R, Brahmer J, et al. Randomized phase II/III trial of paclitaxel (P) plus carboplatin (C) with or without bevacizumab (NSC#704865) in patients with advanced non squamous non small cell lung cancer [abstract]. An Eastern Cooperative Oncology Group (ECOG) trial-E4599. J Clin Oncol (Meeting Abstracts) 2005; 23: LBA4
-
Sandler A, Gray R, Brahmer J, et al. Randomized phase II/III trial of paclitaxel (P) plus carboplatin (C) with or without bevacizumab (NSC#704865) in patients with advanced non squamous non small cell lung cancer [abstract]. An Eastern Cooperative Oncology Group (ECOG) trial-E4599. J Clin Oncol (Meeting Abstracts) 2005; 23: LBA4
-
-
-
-
113
-
-
20244381389
-
Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small-cell lung cancer
-
Herbst RS, Johnson DH, Mininberg E, et al. Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small-cell lung cancer. J Clin Oncol 2005; 23: 2544-55
-
(2005)
J Clin Oncol
, vol.23
, pp. 2544-2555
-
-
Herbst, R.S.1
Johnson, D.H.2
Mininberg, E.3
-
114
-
-
30944446883
-
Lessons from phase III clinical trials on anti-VEGF therapy for cancer
-
Jain RK, Duda DG, Clark JW, et al. Lessons from phase III clinical trials on anti-VEGF therapy for cancer. Nat Clin Pract Oncol 2006; 3: 24-40
-
(2006)
Nat Clin Pract Oncol
, vol.3
, pp. 24-40
-
-
Jain, R.K.1
Duda, D.G.2
Clark, J.W.3
-
115
-
-
1342268525
-
American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: Update 2003
-
Pfister DG, Johnson DH, Azzoli CG, et al. American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update 2003. J Clin Oncol 2004; 22: 330-53
-
(2004)
J Clin Oncol
, vol.22
, pp. 330-353
-
-
Pfister, D.G.1
Johnson, D.H.2
Azzoli, C.G.3
|