Pharmacological and computational analysis of alpha-subunit preferential GABAA positive allosteric modulators on the rat septo-hippocampal activity

Neuropharmacology

Volumn 52, Issue 3, 2007, Pages 733-743

  Ujfalussy, Balázs ^a,b   Kiss, Tamás ^a   Orbán, Gergo ^a   Hoffmann, William E ^c   Érdi, Péter ^a,b   Hajós, Mihály ^c  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^b KALAMAZOO COLLEGE   (United States)

^c PFIZER INC   (United States)

Author keywords

Allosteric modulators; Anxiety; EEG; Hippocampus; Medial septum; Theta

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 7 TERT BUTYL 3 (2,5 DIFLUOROPHENYL) 6 (2 METHYL 2H 1,2,4 TRIAZOL 3 YLMETHOXY) 1,2,4 TRIAZOLO[4,3 B]PYRIDAZINE; ANXIOLYTIC AGENT; BENZODIAZEPINE DERIVATIVE; FLUMAZENIL; RECEPTOR SUBTYPE; RECEPTOR SUBUNIT; ZOLPIDEM;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ELECTROENCEPHALOGRAM; HIPPOCAMPUS; IN VIVO STUDY; MALE; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; NERVE CELL NETWORK; NEUROPHARMACOLOGY; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; RAT; SEPTUM PELLUCIDUM; THETA RHYTHM; TRANQUILIZING ACTIVITY;

ACTION POTENTIALS; ANIMALS; ELECTROENCEPHALOGRAPHY; FLUOROBENZENES; GABA AGONISTS; GABA ANTAGONISTS; HIPPOCAMPUS; MALE; MODELS, NEUROLOGICAL; NEURAL NETWORKS (COMPUTER); NEURAL PATHWAYS; NEURONS; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SEPTUM OF BRAIN; TRIAZOLES;

EID: 33846881808     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2006.09.022     Document Type: Article

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