Evidence that the mechanism of antibody-catalysed hydrolysis of arylcarbamates can be determined by the structure of the immunogen used to elicit the catalytic antibody

Biochemical Journal

Volumn 401, Issue 3, 2007, Pages 721-726

  Boucher, Guillaume ^a   Said, Bilal ^a   Ostler, Elizabeth L ^a   Resmini, Marina ^b   Brocklehurst, Keith ^b   Gallacher, Gerard ^a  

^a UNIVERSITY OF BRIGHTON   (United Kingdom)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Antibody; Catalytic antibody; Hydrolysis; Mechanism

Indexed keywords

ANTIBODIES; CATALYSIS; HYDROLYSIS; IMMUNOLOGY; REACTION KINETICS; SUBSTITUTION REACTIONS; SUBSTRATES;

CARBAMATE SUBSTRATES; CATALYTIC ANTIBODIES; MICHAELIS-MENTEN EQUATIONS; PHOSPHONAMIDATE HAPTEN;

AROMATIC COMPOUNDS;

ANION; CARBAMIC ACID DERIVATIVE; CATALYTIC ANTIBODY; HAPTEN; PHENYL GROUP; PHOSPHATE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE;

ARTICLE; CATALYSIS; HYDROLYSIS; MICHAELIS MENTEN KINETICS; MOLECULAR RECOGNITION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTIBODIES, CATALYTIC; ANTIBODY SPECIFICITY; ANTIGENS; CARBAMATES; CATALYSIS; HAPTENS; HYDROLYSIS; KINETICS; SHEEP;

EID: 33846876098     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20060551     Document Type: Article

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