MEN 11270, a novel selective constrained peptide antagonist with high affinity at the human B2 kinin receptor

Journal of Pharmacology and Experimental Therapeutics

Volumn 289, Issue 3, 1999, Pages 1250-1256

  Meini, Stefania ^a   Quartara, Laura ^a   Rizzi, Anna ^b   Patacchini, Riccardo ^a   Cucchi, Paola ^a   Giolitti, Alessandro ^a   Calò, Girolamo ^b   Regoli, Domenico ^b   Criscuoli, Marco ^a   Maggi, Carlo A ^a  

^a Menarini Ricerche SpA   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

3 (6 ACETAMIDO 3 PYRIDYL) N [N [2,4 DICHLORO 3 [(2 METHYL 8 QUINOLINYL)OXYMETHYL]PHENYL] N METHYLAMINOCARBONYLMETHYL]ACRYLAMIDE; [[4 [2 [[BIS(CYCLOHEXYLAMINO)METHYLENE]AMINO] 3 (2 NAPHTHYL)PROPIONAMIDO]PHENYL]METHYL]TRIBUTYLPHOSPHONIUM CHLORIDE; B 9430; BRADYKININ; BRADYKININ B2 RECEPTOR ANTAGONIST; ICATIBANT; LYSYLLYSYLARGINYLPROLYL(4 HYDROXYPROLYL)GLYCYL 2 (2,3 DIHYDRO 1H INDEN 2 YL)GLYCYLSERYL 2 (2,3 DIHYDRO 1H INDEN 2 YL)GLYCYLOCTAHYDRO 1H INDOLE 2 CARBOXYLIC ACID; MEN 11270; NORADRENALIN; SEROTONIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; DRUG CONFORMATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BINDING, COMPETITIVE; BIOLOGICAL ASSAY; BRADYKININ; CELL LINE; CELL MEMBRANE; FEMALE; HUMANS; KINETICS; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; NOREPINEPHRINE; OLIGOPEPTIDES; PEPTIDES, CYCLIC; PREGNANCY; QUINOLINES; RECEPTOR, BRADYKININ B2; RECEPTORS, BRADYKININ; SEROTONIN; STRUCTURE-ACTIVITY RELATIONSHIP; UMBILICAL VEINS;

EID: 0032992586     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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