Antinociceptive profile of the pseudopeptide B2 bradykinin receptor antagonist NPC 18688 in mice

British Journal of Pharmacology

Volumn 117, Issue 3, 1996, Pages 552-558

  Corrêa, Clovis R ^a   Kyle, Donald J ^b   Chakraverty, Sarvajit ^b   Calixto, João B ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

^b Scios Nova Inc   (United States)

Author keywords

Anti hyperalgesic action; B1 and B2 receptor; Bradykinin; Formalin and capsaicin induced pain; Mouse and rat paw oedema; NPC 18688; Pseudopeptide; Writhing test

Indexed keywords

ACETYLCHOLINE; BRADYKININ; BRADYKININ B1 RECEPTOR; BRADYKININ B2 RECEPTOR; BRADYKININ B2 RECEPTOR ANTAGONIST; BRADYKININ DERIVATIVE; ICATIBANT; NPC 18688; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DRUG INHIBITION; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; GUINEA PIG; HOT PLATE TEST; HYPOTENSION; ILEUM CONTRACTION; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MEAN ARTERIAL PRESSURE; MOUSE; NOCICEPTION; NONHUMAN; PAIN; PAW EDEMA; PRIORITY JOURNAL; RAT; RECTUS ABDOMINIS MUSCLE; SUBCUTANEOUS DRUG ADMINISTRATION; TAIL FLICK TEST; TOAD;

EID: 0030021844     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1476-5381.1996.tb15226.x     Document Type: Article

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