A double-blind, placebo-controlled, crossover study of osmotic release oral system methylphenidate in adults with ADHD with assessment of oppositional and emotional dimensions of the disorder

Journal of Clinical Psychiatry

Volumn 68, Issue 1, 2007, Pages 93-101

  Reimherr, Frederick W ^a   Williams, Erika D ^a   Strong, Robert E ^a   Mestas, Ruth ^a   Soni, Poonam ^a   Marchant, Barrie K ^a  

^a UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

METHYLPHENIDATE; PLACEBO;

ADULT; AGITATION; ANXIETY; ARTICLE; ATTENTION DEFICIT DISORDER; BEHAVIOR DISORDER; CLINICAL ARTICLE; CLINICAL FEATURE; CLINICAL TRIAL; COLD CLAMMY SKIN; COMORBIDITY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DECREASED APPETITE; DISEASE CLASSIFICATION; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG DELIVERY SYSTEM; DRUG DOSE COMPARISON; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG HALF LIFE; DRUG RELEASE; DRY EYE; DRY NOSE; EMOTIONALITY; FEMALE; HEADACHE; HUMAN; INSOMNIA; MALE; NAUSEA; OSMOSIS; OUTCOME ASSESSMENT; PAIN; PRIORITY JOURNAL; RATING SCALE; SIDE EFFECT; SYMPTOMATOLOGY; TENSION; URINARY DYSFUNCTION; XEROSTOMIA;

EID: 33846874096     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: 10.4088/JCP.v68n0113     Document Type: Article

References (26)

1. Weiss G, Hechtman L, Milroy T, et al. Psychiatric status of hyperactives as adults: a controlled prospective 15-year follow-up of 63 hyperactive children. J Am Acad Child Psychiatry 1985;24:211-220
2. Barkley RA, Fischer M, Smallish L, et al. The persistence of attention-deficit/hyperactivity disorder into young adulthood as a function of reporting source and definition of disorder. J Abnorm Psychol 2002;111:279-289
3. Wood DR, Reimherr FW, Wender PH, et al. Diagnosis and treatment of minimal brain dysfunction in adults: a preliminary report. Arch Gen Psychiatry 1976;33:1453-1460
4. Swanson J, Gupta S, Guinta D, et al. Acute tolerance to methylphenidate in the treatment of attention deficit hyperactivity disorder in children. Clin Pharmacol Ther 1999;66:295-305
5. Acosta MT, Arcos-Burgos M, Muenke M. Attention deficit/hyperactivity disorder (ADHD): complex phenotype, simple genotype? Genet Med 2004;6:1-15
6. Milberger S, Biederman J, Faraone SV, et al. Associations between ADHD and psychoactive substance use disorders: findings from a longitudinal study of high-risk siblings of ADHD children. Am J Addict 1997;6:318-329
7. Biederman J, Mick E, Faraone SV, et al. Influence of gender on attention deficit hyperactivity disorder in children referred to a psychiatric clinic. Am J Psychiatry 2002;159:36-42
8. Biederman J, Faraone SV, Monuteaux MC, et al. Gender effects on attention-deficit/hyperactivity disorder in adults, revisited. Biol Psychiatry 2004;55:692-700
9. Jensen PS, Hinshaw SP, Kraemer HC, et al. ADHD comorbidity findings from the MTA study: comparing comorbid subgroups. J Am Acad Child Adolesc Psychiatry 2001;40:147-158
10. Pelham WE, Gnagy EM, Burrows-Maclean L, et al. Once-a-day Concerta methylphenidate versus 3-times-daily methylphenidate in laboratory and natural settings. Pediatrics 2001;107:E105
11. Wender PH. Attention-Deficit Hyperactivity Disorder in Adults. New York, NY: Oxford University Press; 1995
12. Reimherr FW, Marchant BK, Strong RE, et al. Emotional dysregulation in adult ADHD and response to atomoxetine. Biol Psychiatry 2005;58:125-131
13. Adler LA, Spencer T, Faraone SV. Validity of pilot adult ADHD Self-Report Scale (ASRS) to rate adult ADHD symptoms. Ann Clin Psychiatry 2006;18:145-148
14. Guy W. ECDEU Assessment Manual for Psychopharmacology. US Dept Health, Education, and Welfare publication (ADM) 76-338. Rockville, Md: National Institute of Mental Health; 1976:218-222
15. Conners CK, Erhardt D, Sparrow EP. Conner's Adult ADHD Rating Scales (CAARS): Technical Manual. North Tonawanda, NY: Multi-Health Systems Inc; 1999
16. Weissman MM, Bothwell S. Assessment of social adjustment by patient self-report. Arch Gen Psychiatry 1976;33:1111-1115
17. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960;23:56-62
18. Reimherr FW, Wender PH, Marchant BK, et al. The Wender-Reimherr Adult Attention Deficit Disorder Scale as a research tool [poster]. Presented at the 42nd annual meeting of the American College of Neuropsychopharmacology; Dec 7-11, 2003; San Juan. Puerto Rico
19. Faraone SV, Spencer T, Aleardi M, et al. Meta-analysis of the efficacy of methylphenidate for treating adult attention-deficit/hyperactivity disorder. J Clin Psychopharmacol 2004;24:24-29
20. Biederman J, Mick E, Surman C, et al. A randomized, placebo-controlled trial of OROS methylphenidate in adults with attention-deficit/hyperactivity disorder. Biol Psychiatry 2005;59:829-835
21. Spencer T, Biederman J, Wilens TE, et al. Is attention-deficit hyperactivity disorder in adults a valid disorder? Harv Rev Psychiatry 1994;1:326-335
22. Spencer T, Biederman J, Wilens TE, et al. Adults with attention-deficit/hyperactivity disorder: a controversial diagnosis. J Clin Psychiatry 1998;59(suppl 7):59-68
23. Faraone SV, Biederman J, Spencer T, et al. Attention-deficit/ hyperactivity disorder in adults: an overview. Biol Psychiatry 2000;48:9-20
24. Barkley RA. Attention Deficit Hyperactivity Disorder. New York, NY: The Guilford Press; 1998
25. Murphy KR, Barkley RA, Bush T. Young adults with attention deficit hyperactivity disorder: subtype differences in comorbidity, educational, and clinical history. J Nerv Ment Dis 2002;190:147-157
26. Newcorn JH, Spencer TJ, Biederman J, et al. Atomoxetine treatment in children and adolescents with attention-deficit/hyperactivity disorder and comorbid oppositional defiant disorder. J Am Acad Child Adolesc Psychiatry 2005;44:240-248