Structure-function Analysis of a Bacterial Deoxyadenosine Kinase Reveals the Basis for Substrate Specificity

Journal of Molecular Biology

Volumn 366, Issue 5, 2007, Pages 1615-1623

  Welin, Martin ^a   Wang, Liya ^a   Eriksson, Staffan ^a   Eklund, Hans ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

crystal structure; deoxyadenosine kinase; drug design; mycoplasma; substrate specificity

Indexed keywords

BACTERIAL ENZYME; DEOXYADENOSINE KINASE; DEOXYADENOSINE TRIPHOSPHATE; DEOXYCYTIDINE PHOSPHATE DEAMINASE; DEOXYCYTIDINE TRIPHOSPHATE; DEOXYRIBONUCLEOSIDE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIUM COLONY; BINDING SITE; COMPLEX FORMATION; CRYSTALLIZATION; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME STRUCTURE; MYCOPLASMA MYCOIDES; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

BACTERIA (MICROORGANISMS); MYCOPLASMA; MYCOPLASMA MYCOIDES SUBSP. MYCOIDES;

EID: 33846847771     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2006.12.010     Document Type: Article

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