Vaccine-based, long-term, stable control of simian/human immunodeficiency virus 89.6PD replication in rhesus macaques

Journal of General Virology

Volumn 88, Issue 2, 2007, Pages 652-659

  Yamamoto, Hiroyuki ^a,b   Kawada, Miki ^a,b   Tsukamoto, Tetsuo ^a,b   Takeda, Akiko ^a,b   Igarashi, Hiroko ^b   Miyazawa, Masaaki ^c   Naruse, Taeko ^d   Yasunami, Michio ^d   Kimura, Akinori ^d   Matano, Tetsuro ^a,b,e,f  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^e NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^f NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; GAG PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; NEUTRALIZING ANTIBODY; PLASMID DNA; VIRUS VECTOR;

ANIMAL EXPERIMENT; ARTICLE; CYTOTOXIC T LYMPHOCYTE; DRUG SYNTHESIS; FOLLOW UP; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNE RESPONSE; INFECTION CONTROL; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RHESUS MONKEY; SIMIAN IMMUNODEFICIENCY VIRUS; VIRAL GENE THERAPY; VIRUS INHIBITION; VIRUS REPLICATION;

AIDS VACCINES; ANIMALS; ANTIBODIES, VIRAL; HIV ANTIBODIES; HIV INFECTIONS; HIV-1; HUMANS; MACACA MULATTA; NEUTRALIZATION TESTS; SAIDS VACCINES; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; T-LYMPHOCYTES; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA; MACACA MULATTA; SIMIAN IMMUNODEFICIENCY VIRUS; SIMIAN-HUMAN IMMUNODEFICIENCY VIRUS;

EID: 33846840778     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.82469-0     Document Type: Article

References (45)

1. Albritton, L. M., Tseng, L., Scadden, D. & Cunningham, J. M. (1989). A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection. Cell 57, 659-666.
2. Amara, R. R., Villinger, F., Altman, J. D., Lydy, S. L., O'Neil, S. P., Staprans, S. I., Montefiori, D. C., Xu, Y., Herndon, J. G. & other authors (2001). Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine. Science 292, 69-74.
3. Amara, R. R., Smith, J. M., Staprans, S. I., Montefiori, D. C., Villinger, F., Altman, J. D., O'Neil, S. P., Kozyr, N. L., Xu, Y. & other authors (2002). Critical role for Env as well as Gag-Pol in control of a simian-human immunodeficiency virus 89.6P challenge by a DNA prime/recombinant modified vaccinia virus Ankara vaccine. J Virol 76, 6138-6146.
4. Arguello, J. R., Little, A. M., Pay, A. L., Gailardo, D., Rojas, I., Marsh, S. G., Goldman, J. M. & Madrigal, J. A. (1998). Mutation detection and typing of polymorphic loci through double-strand conformation analysis. Nat Genet 18, 192-194.
5. Barouch, D. H., Santra, S., Schmitz, J. E., Kuroda, M. J., Fu, T. M., Wagner, W., Bliska, M., Craiu, A., Zheng, X. X. & other authors (2000). Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination. Science 290, 486-492.
6. + cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. J Virol 68, 6103-61101
7. Borrow, P., Lewicki, H., Wei, X., Horwitz, M. S., Peffer, N., Meyers, H., Nelson, J. A., Gairin, J. E., Hahn, B. H. & other authors (1997). Antiviral pressure exerted by HIV-1-specific cytotoxic T lymphocytes (CTL) during primary, infection demonstrated by rapid selection of CTL escape virus. Nat Med 3, 205-211.
8. Casimiro, D. R., Wang, F., Schleif, W. A., Liang, X., Zhang, Z. Q., Tobery, T. W., Davies, M. E., McDermott, A. B., O'Connor, D. H. & other authors (2005). Attenuation of simian immunodeficiency virus SIVmac239 infection by prophylactic immunization with DNA and recombinant adenoviral vaccine vectors expressing Gag. J Virol 79, 15547-15555.
9. Feinberg, M. B. & Moore, J. P. (2002). AIDS vaccine models: challenging challenge viruses. Nat Med 8, 207-210.
10. Goulder, P. J. & Watkins, D. I. (2004). HIV and SIV CTL escape: implications for vaccine design. Nat Rev Immunol 4, 630-640.
11. Goulder, P. J., Phillips, R. E., Colbert, R. A., McAdam, S., Ogg, G., Nowak M. A., Giangrande, P., Luzzi, G., Morgan, B. & other authors (1997). Late escape from an immunodominant cy-totoxic T-lymphocyte response associated with progression to AIDS. Nat Med 3, 212-217.
12. Horton, H., Vogel, T. U., Carter, D. K., Vielhuber, K., Fuller, D. H., Shipley, T., Fuller, J. T., Kunstman, K. J., Sutter, G. & other authors (2002). Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression following challenge with pathogenic SIVmac239. J Virol 76, 7187-7202.
13. + T cell depletion in simian immunodeficiency virus-infected macaques. J Exp Med 189, 991-998.
14. Kano, M., Matano, T., Kato, A., Nakamura, H., Takeda, A., Suzaki, Y., Ami, Y., Terao, K. & Nagai, Y. (2002). Primary replication of a recombinant Sendai virus vector in macaques. J Gen Virol 83, 1377-1386.
15. Kato, A., Sakai, Y., Shioda, T., Kondo, T., Nakanishi, M. & Nagai, Y. (1996). Initiation of Sendai virus multiplication from transfected cDNA or RNA with negative or positive sense. Genes Cells 1, 569-579.
16. Kawada, M., Igarashi, H., Takeda, A., Tsukamoto, T., Yamamoto, H., Dohki, S., Takiguchi, M. & Matano, T. (2006). Involvement of multiple epitope-specific cytotoxic T-lymphocyte responses in vaccine-based control of simian immunodeficiency virus replication in rhesus macaques. J Virol 80, 1949-1958.
17. Koup, R. A., Safrit, J. T., Cao, Y., Andrews, C. A., McLeod, G., Borkowsky, W., Farthing, C. & Ho, D. D. (1994). Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J Virol 68, 4650-4655.
18. + central memory T cells and survival in vaccinated SIV-challenged monkeys. Science 312, 1530-1533.
19. Li, H. O., Zhu, Y. F., Asakawa, M., Kuma, H., Hirata, T., Ueda, Y., Lee, Y. S., Fukumura, M., Iida, A. & other authors (2000). A cytoplasmic RNA vector derived from nontransmissible Sendai virus with efficient gene transfer and expression. J Virol 74, 6564-6569.
20. + T cells. Nature 434, 1148-1152.
21. Lu, Y., Pauza, C. D., Lu, X., Montefiori, D. C. & Miller, C. J. (1998). Rhesus macaques that become systemically infected with pathogenic SHIV 89.6-PD after intravenous, rectal, or vaginal inoculation and fail to make an antiviral antibody response rapidly develop AIDS. J Acquir Immune Defic Syndr Hum Retrovirol 19, 6-18.
22. Matano, T., Shibata, R., Siemon, C., Connors, M., Lane, H. C. & Martin, M. A. (1998). Administration of an anti-CD8 monoclonal antibody interferes with the clearance of chimeric simian/human immunodeficiency virus during primary infections of rhesus macaques. J Virol 72, 164-169.
23. Matano, T., Kano, M., Odawara, T., Nakamura, H., Takeda, A., Mori, K., Sato, T. & Nagai, Y. (2000). Induction of protective immunity against pathogenic simian immunodeficiency virus by a foreign receptor-dependent replication of an engineered avirulent virus. Vaccine 18, 3310-3318.
24. Matano, T., Kano, M., Nakamura, H., Takeda, A., & Nagai, Y. (2001). Rapid appearance of secondary immune responses and protection from acute CD4 depletion after a highly pathogenic immunodeficiency virus challenge in macaques vaccinated with a DNA prime/Sendai virus vector boost regimen. J Virol 75, 11891-11896.
25. Matano, T., Kobayashi, M., Igarashi, H., Takeda, A., Nakamura, H., Kano, M., Sugimoto, C., Mori, K., Iida, A. & other authors (2004). Cytotoxic T lymphocyte-based control of simian immunodeficiency virus replication in a preclinical AIDS vaccine trial. J Exp Med 199, 1709-1718.
26. + T cells in multiple tissues during acute SIV infection. Nature 434, 1093-1097.
27. Mattapallil, J. J., Douek, D. C., Buckler-White, A., Monteflori, D. C., Letvin, N. L., Nabel, G. J. & Roederer, M. (2006). Vaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challenge. J Exp Med 203, 1533-1541.
28. McMichael, A. J. & Hanke, T. (2003). HIV vaccines 1983-2003. Nat Med 9, 874-880.
29. + T cell subsets in rhesus monkeys, explaining their divergent clinical courses. Proc Natl Acad Sci U S A 101, 12324-12329.
30. + T cells are massively infected and eliminated by X4-tropic simian-human immunodeficiency viruses in macaques. Proc Natl Acad Sci U S A 102, 8000-8005.
31. Ogg, G. S., Jin, X., Bonhoeffer, S., Dunbar, P. R., Nowak, M. A., Monard, S, Segal, J. P., Cao, Y., Rowland-Jones, S. L. & other authors (1998). Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA. Science 279, 2103-2106.
32. Picker, L. J. & Watkins, D. I. (2005). HIV pathogenesis: the first cut is the deepest. Nat Immunol 6, 430-432.
33. + memory T cells in rapidly progressive simian immunodeficiency virus infection. J Exp Med 200, 1299-1314.
34. Price, D. A., Goulder, P. J., Klenerman, P., Sewell, A. K., Easterbrook P. J., Troop, M, Bangham, C. R. & Phillips, R. E. (1997). Positive selection of HIV-1 cytotoxic T lymphocyte escape variants during primary infection. Proc Natl Acad Sci U S A 94, 1890-1895.
35. + T-cell-depleted macaques. AIDS 16, 829-838.
36. Reimann, K A., Li, J. T., Veazey, R., Halloran, M., Park, I. W., Karlsson, G. B., Sodroski, J. & Letvin, N. L. (1996). A chimeric simian/ human immunodeficiency virus expressing a primary patient human immuno-deficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys. J Virol 70, 6922-6928.
37. Rose, N. F., Marx, P. A., Luckay, A., Nixon, D. F., Moretto, W. J., Donahoe, S. M., Mantefiori, D., Roberts, A., Buonocore, L. & Rose, J. K. (2001). An effective AIDS vaccine based on live attenuated vesicular stomatitis virus recombinants. Cell 106, 539-549.
38. Sadagopal, S., Amara, R. R., Monteflori, D. C., Wyatt, L. S., Staprans, S. I., Kozyr, N. L., McClure, H. M., Moss, B. & Robinson, H. L. (2005). Signature for long-term vaccine- mediated control of a simian and human immunodeficiency virus 89.6P challenge: stable low-breadth and tow-frequency T-cell response capable of coproducing gamma interferon and interleukin-2. J Virol 79, 3243-3253.
39. + lymphocytes. Science 283, 857-860.
40. Shibata, R., Maldarelli, F., Siemon, C., Matano, T., Parta, M., Miller, G., Fredrickson, T. & Martin, M. A. (1997a). Infection and pathogenicity of chimeric simian-human immunodeficiency viruses in macaques: determinants of high virus loads and CD4 cell killing. J Infect Dis 176, 362-373.
41. Shibata, R., Siemon, C., Czajak, S. C., Desrosiers, R. C. & Martin, M. A. (1997b). Live, attenuated simian immunodeficiency virus vaccines elicit potent resistance against a challenge with a human immuno-deficiency virus type 1 chimeric virus. J Virol 71, 8141-8148.
42. Shiver, J. W., Fu, T. M., Chen, L., Casimiro, D. R., Davies, M. E., Evans, R. K, Zhang, Z. O., Simon, A. J., Trigona, W. L. & other authors (2002). Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunity. Nature 415, 331-335.
43. Takeda, A., Igarashi, H., Nakamura, H., Kano, M., Iida, A., Hirata, T., Hasegawa, M., Nagai, Y. & Matano, T. (2003). Protective efficacy of an AIDS vaccine, a single DNA-priming followed by a single booster with a recombinant replication-defective Sendai virus vector, in a macaque AIDS model. J Virol 77, 9710-9715.
44. Willey, R. L., Byrum, R., Piatak, M., Kim, Y. B., Cho, M. W., Rossio, J. L., Jr, Bess, J., Jr, Igarashi, T., Endo, Y. & other authors (2003). Control of viremia and prevention of simian-human immunodeficiency virus-induced disease in rhesus macaques immunized with recombinant vaccinia viruses plus inactivated simian immunodeficiency virus and human immunodeficiency virus type 1 particles. J Virol 77, 1163-1174.
45. Wilson, N. A., Reed, J., Napoe, G. S., Piaskowski, S., Szymanski, A., Furlott, J., Gonzalez, E. J., Yant, L. J., Maness, N. J. & other authors (2006). Vaccine-induced cellular immune responses reduce plasma viral concentrations after repeated low-dose challenge with pathogenic simian immunodeficiency virus SIVmac239. J Virol 80, 5875-5885.