메뉴 건너뛰기




Volumn 8, Issue 2, 2007, Pages 169-175

Genetic susceptibility to obstructive sleep apnea in the obese child

Author keywords

Apolipoprotein E; Central adiposity; Childhood obesity; Childhood OSA; Gene environment interaction; Intermediate phenotypes of OSA

Indexed keywords

CASE CONTROL STUDY; CHILD; CHILDHOOD DISEASE; DISEASE ASSOCIATION; GENE INTERACTION; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; HAPLOTYPE; HUMAN; MORBIDITY; OBESITY; PATHOGENESIS; PHENOTYPE; PREDICTION; PRIORITY JOURNAL; PUBLIC HEALTH; REVIEW; SLEEP APNEA SYNDROME;

EID: 33846828395     PISSN: 13899457     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.sleep.2006.09.003     Document Type: Review
Times cited : (19)

References (63)
  • 1
    • 0037142964 scopus 로고    scopus 로고
    • Obstructive sleep apnoea
    • Malhotra A., and White D.P. Obstructive sleep apnoea. Lancet 360 9328 (2002) 237-245
    • (2002) Lancet , vol.360 , Issue.9328 , pp. 237-245
    • Malhotra, A.1    White, D.P.2
  • 2
    • 0024369391 scopus 로고
    • Sleep-associated breathing disorders in morbidly obese children and adolescents
    • Mallory Jr. G.B., Fiser D.H., and Jackson R. Sleep-associated breathing disorders in morbidly obese children and adolescents. J Pediatr 115 6 (1989) 892-897
    • (1989) J Pediatr , vol.115 , Issue.6 , pp. 892-897
    • Mallory Jr., G.B.1    Fiser, D.H.2    Jackson, R.3
  • 3
    • 33644674754 scopus 로고    scopus 로고
    • Obstructive sleep apnea in extremely overweight adolescents undergoing bariatric surgery
    • Kalra M., Inge T., Garcia V., Daniels S., Lawson L., Curti R., et al. Obstructive sleep apnea in extremely overweight adolescents undergoing bariatric surgery. Obes Res 13 7 (2005) 1175-1179
    • (2005) Obes Res , vol.13 , Issue.7 , pp. 1175-1179
    • Kalra, M.1    Inge, T.2    Garcia, V.3    Daniels, S.4    Lawson, L.5    Curti, R.6
  • 5
    • 0037092561 scopus 로고    scopus 로고
    • Left ventricular hypertrophy and abnormal ventricular geometry in children and adolescents with obstructive sleep apnea
    • Amin R.S., Kimball T.R., Bean J.A., Jeffries J.L., Willging J.P., Cotton R.T., et al. Left ventricular hypertrophy and abnormal ventricular geometry in children and adolescents with obstructive sleep apnea. Am J Respir Crit Care Med 165 10 (2002) 1395-1399
    • (2002) Am J Respir Crit Care Med , vol.165 , Issue.10 , pp. 1395-1399
    • Amin, R.S.1    Kimball, T.R.2    Bean, J.A.3    Jeffries, J.L.4    Willging, J.P.5    Cotton, R.T.6
  • 6
    • 0035751208 scopus 로고    scopus 로고
    • Morbidity of obstructive sleep apnea in children: facts and theory
    • Gozal D. Morbidity of obstructive sleep apnea in children: facts and theory. Sleep Breath 5 1 (2001) 35-42
    • (2001) Sleep Breath , vol.5 , Issue.1 , pp. 35-42
    • Gozal, D.1
  • 7
    • 0036082409 scopus 로고    scopus 로고
    • Metabolic correlates with obstructive sleep apnea in obese subjects
    • de la Eva R.C., Baur L.A., Donaghue K.C., and Waters K.A. Metabolic correlates with obstructive sleep apnea in obese subjects. J Pediatr 140 6 (2002) 654-659
    • (2002) J Pediatr , vol.140 , Issue.6 , pp. 654-659
    • de la Eva, R.C.1    Baur, L.A.2    Donaghue, K.C.3    Waters, K.A.4
  • 8
    • 0037214371 scopus 로고    scopus 로고
    • Upper airway size analysis by magnetic resonance imaging of children with obstructive sleep apnea syndrome
    • Arens R., McDonough J.M., Corbin A.M., Rubin N.K., Carroll M.E., Pack A.I., et al. Upper airway size analysis by magnetic resonance imaging of children with obstructive sleep apnea syndrome. Am J Respir Crit Care Med 167 1 (2003) 65-70
    • (2003) Am J Respir Crit Care Med , vol.167 , Issue.1 , pp. 65-70
    • Arens, R.1    McDonough, J.M.2    Corbin, A.M.3    Rubin, N.K.4    Carroll, M.E.5    Pack, A.I.6
  • 9
    • 0042376069 scopus 로고    scopus 로고
    • Identification of upper airway anatomic risk factors for obstructive sleep apnea with volumetric magnetic resonance imaging
    • Schwab R.J., Pasirstein M., Pierson R., Mackley A., Hachadoorian R., Arens R., et al. Identification of upper airway anatomic risk factors for obstructive sleep apnea with volumetric magnetic resonance imaging. Am J Respir Crit Care Med 168 5 (2003) 522-530
    • (2003) Am J Respir Crit Care Med , vol.168 , Issue.5 , pp. 522-530
    • Schwab, R.J.1    Pasirstein, M.2    Pierson, R.3    Mackley, A.4    Hachadoorian, R.5    Arens, R.6
  • 10
    • 1842475952 scopus 로고    scopus 로고
    • Computed tomographic evaluation of the role of craniofacial and upper airway morphology in obstructive sleep apnea in Chinese
    • Lam B., Ooi C.G., Peh W.C., Lauder I., Tsang K.W., Lam W.K., et al. Computed tomographic evaluation of the role of craniofacial and upper airway morphology in obstructive sleep apnea in Chinese. Respir Med 98 4 (2004) 301-307
    • (2004) Respir Med , vol.98 , Issue.4 , pp. 301-307
    • Lam, B.1    Ooi, C.G.2    Peh, W.C.3    Lauder, I.4    Tsang, K.W.5    Lam, W.K.6
  • 11
    • 0035057557 scopus 로고    scopus 로고
    • The relationship between craniofacial morphology and obstructive sleep apnea in whites and in African-Americans
    • Cakirer B., Hans M.G., Graham G., Aylor J., Tishler P.V., and Redline S. The relationship between craniofacial morphology and obstructive sleep apnea in whites and in African-Americans. Am J Respir Crit Care Med 163 4 (2001) 947-950
    • (2001) Am J Respir Crit Care Med , vol.163 , Issue.4 , pp. 947-950
    • Cakirer, B.1    Hans, M.G.2    Graham, G.3    Aylor, J.4    Tishler, P.V.5    Redline, S.6
  • 13
    • 0030076637 scopus 로고    scopus 로고
    • Craniofacial structure and obstructive sleep apnea syndrome-a qualitative analysis and meta-analysis of the literature
    • Miles P.G., Vig P.S., Weyant R.J., Forrest T.D., and Rockette Jr. H.E. Craniofacial structure and obstructive sleep apnea syndrome-a qualitative analysis and meta-analysis of the literature. Am J Orthod Dentofacial Orthop 109 2 (1996) 163-172
    • (1996) Am J Orthod Dentofacial Orthop , vol.109 , Issue.2 , pp. 163-172
    • Miles, P.G.1    Vig, P.S.2    Weyant, R.J.3    Forrest, T.D.4    Rockette Jr., H.E.5
  • 14
  • 15
    • 0024365525 scopus 로고
    • Sites and sizes of fat deposits around the pharynx in obese patients with obstructive sleep apnoea and weight matched controls
    • Horner R.L., Mohiaddin R.H., Lowell D.G., Shea S.A., Burman E.D., Longmore D.B., et al. Sites and sizes of fat deposits around the pharynx in obese patients with obstructive sleep apnoea and weight matched controls. Eur Respir J 2 7 (1989) 613-622
    • (1989) Eur Respir J , vol.2 , Issue.7 , pp. 613-622
    • Horner, R.L.1    Mohiaddin, R.H.2    Lowell, D.G.3    Shea, S.A.4    Burman, E.D.5    Longmore, D.B.6
  • 16
    • 0036384408 scopus 로고    scopus 로고
    • Body fat distribution, serum leptin, and cardiovascular risk factors in men with obstructive sleep apnea
    • Schafer H., Pauleit D., Sudhop T., Gouni-Berthold I., Ewig S., and Berthold H.K. Body fat distribution, serum leptin, and cardiovascular risk factors in men with obstructive sleep apnea. Chest 122 3 (2002) 829-839
    • (2002) Chest , vol.122 , Issue.3 , pp. 829-839
    • Schafer, H.1    Pauleit, D.2    Sudhop, T.3    Gouni-Berthold, I.4    Ewig, S.5    Berthold, H.K.6
  • 17
    • 0025998959 scopus 로고
    • Effect of weight loss on upper airway collapsibility in obstructive sleep apnea
    • Schwartz A.R., Gold A.R., Schubert N., Stryzak A., Wise R.A., Permutt S., et al. Effect of weight loss on upper airway collapsibility in obstructive sleep apnea. Am Rev Respir Dis 144 3 Pt 1 (1991) 494-498
    • (1991) Am Rev Respir Dis , vol.144 , Issue.3 PART 1 , pp. 494-498
    • Schwartz, A.R.1    Gold, A.R.2    Schubert, N.3    Stryzak, A.4    Wise, R.A.5    Permutt, S.6
  • 18
    • 0141617563 scopus 로고    scopus 로고
    • Genioglossus activity in children with obstructive sleep apnea during wakefulness and sleep onset
    • Katz E.S., and White D.P. Genioglossus activity in children with obstructive sleep apnea during wakefulness and sleep onset. Am J Respir Crit Care Med 168 6 (2003) 664-670
    • (2003) Am J Respir Crit Care Med , vol.168 , Issue.6 , pp. 664-670
    • Katz, E.S.1    White, D.P.2
  • 19
    • 0026750217 scopus 로고
    • Waking genioglossal electromyogram in sleep apnea patients versus normal controls (a neuromuscular compensatory mechanism)
    • Mezzanotte W.S., Tangel D.J., and White D.P. Waking genioglossal electromyogram in sleep apnea patients versus normal controls (a neuromuscular compensatory mechanism). J Clin Invest 89 5 (1992) 1571-1579
    • (1992) J Clin Invest , vol.89 , Issue.5 , pp. 1571-1579
    • Mezzanotte, W.S.1    Tangel, D.J.2    White, D.P.3
  • 20
    • 0029994094 scopus 로고    scopus 로고
    • Influence of sleep onset on upper-airway muscle activity in apnea patients versus normal controls
    • Mezzanotte W.S., Tangel D.J., and White D.P. Influence of sleep onset on upper-airway muscle activity in apnea patients versus normal controls. Am J Respir Crit Care Med 153 6 Pt 1 (1996) 1880-1887
    • (1996) Am J Respir Crit Care Med , vol.153 , Issue.6 PART 1 , pp. 1880-1887
    • Mezzanotte, W.S.1    Tangel, D.J.2    White, D.P.3
  • 21
    • 19644380907 scopus 로고    scopus 로고
    • Changes in upper airway size during tidal breathing in children with obstructive sleep apnea syndrome
    • Arens R., Sin S., McDonough J.M., Palmer J.M., Dominguez T., Meyer H., et al. Changes in upper airway size during tidal breathing in children with obstructive sleep apnea syndrome. Am J Respir Crit Care Med 171 11 (2005) 1298-1304
    • (2005) Am J Respir Crit Care Med , vol.171 , Issue.11 , pp. 1298-1304
    • Arens, R.1    Sin, S.2    McDonough, J.M.3    Palmer, J.M.4    Dominguez, T.5    Meyer, H.6
  • 22
    • 0027068207 scopus 로고
    • Epidemiology of snoring and obstructive sleep apnoea in a Danish population, age 30-60
    • Jennum P., and Sjol A. Epidemiology of snoring and obstructive sleep apnoea in a Danish population, age 30-60. J Sleep Res 1 4 (1992) 240-244
    • (1992) J Sleep Res , vol.1 , Issue.4 , pp. 240-244
    • Jennum, P.1    Sjol, A.2
  • 23
    • 33646016002 scopus 로고    scopus 로고
    • Atopy as a risk factor for habitual snoring at age 1 year
    • Kalra M., Lemasters G., Bernstein D., Wilson K., Levin L., Cohen A., et al. Atopy as a risk factor for habitual snoring at age 1 year. Chest 129 4 (2006) 942-946
    • (2006) Chest , vol.129 , Issue.4 , pp. 942-946
    • Kalra, M.1    Lemasters, G.2    Bernstein, D.3    Wilson, K.4    Levin, L.5    Cohen, A.6
  • 25
    • 32444432176 scopus 로고    scopus 로고
    • Family aggregation of upper airway soft tissue structures in normal subjects and patients with sleep apnea
    • Schwab R.J., Pasirstein M., Kaplan L., Pierson R., Mackley A., Hachadoorian R., et al. Family aggregation of upper airway soft tissue structures in normal subjects and patients with sleep apnea. Am J Respir Crit Care Med 173 4 (2006) 453-463
    • (2006) Am J Respir Crit Care Med , vol.173 , Issue.4 , pp. 453-463
    • Schwab, R.J.1    Pasirstein, M.2    Kaplan, L.3    Pierson, R.4    Mackley, A.5    Hachadoorian, R.6
  • 26
    • 0029023346 scopus 로고
    • Familial aggregates in obstructive sleep apnea syndrome
    • Guilleminault C., Partinen M., Hollman K., Powell N., and Stoohs R. Familial aggregates in obstructive sleep apnea syndrome. Chest 107 6 (1995) 1545-1551
    • (1995) Chest , vol.107 , Issue.6 , pp. 1545-1551
    • Guilleminault, C.1    Partinen, M.2    Hollman, K.3    Powell, N.4    Stoohs, R.5
  • 27
    • 0028894197 scopus 로고
    • Family studies in patients with the sleep apnea-hypopnea syndrome
    • Mathur R., and Douglas N.J. Family studies in patients with the sleep apnea-hypopnea syndrome. Ann Intern Med 122 3 (1995) 174-178
    • (1995) Ann Intern Med , vol.122 , Issue.3 , pp. 174-178
    • Mathur, R.1    Douglas, N.J.2
  • 30
    • 4143049097 scopus 로고    scopus 로고
    • APOE epsilon4 is associated with obstructive sleep apnea/hypopnea: the sleep heart health study
    • Gottlieb D.J., DeStefano A.L., Foley D.J., Mignot E., Redline S., Givelber R.J., et al. APOE epsilon4 is associated with obstructive sleep apnea/hypopnea: the sleep heart health study. Neurology 63 4 (2004) 664-668
    • (2004) Neurology , vol.63 , Issue.4 , pp. 664-668
    • Gottlieb, D.J.1    DeStefano, A.L.2    Foley, D.J.3    Mignot, E.4    Redline, S.5    Givelber, R.J.6
  • 31
    • 32044474687 scopus 로고    scopus 로고
    • Apolipoprotein E and obstructive sleep apnea: evaluating whether a candidate gene explains a linkage peak
    • Larkin E.K., Patel S.R., Redline S., Mignot E., Elston R.C., and Hallmayer J. Apolipoprotein E and obstructive sleep apnea: evaluating whether a candidate gene explains a linkage peak. Genet Epidemiol 30 2 (2006) 101-110
    • (2006) Genet Epidemiol , vol.30 , Issue.2 , pp. 101-110
    • Larkin, E.K.1    Patel, S.R.2    Redline, S.3    Mignot, E.4    Elston, R.C.5    Hallmayer, J.6
  • 32
    • 0029075560 scopus 로고
    • The transmission/disequilibrium test: history, subdivision, and admixture
    • Ewens W.J., and Spielman R.S. The transmission/disequilibrium test: history, subdivision, and admixture. Am J Hum Genet 57 2 (1995) 455-464
    • (1995) Am J Hum Genet , vol.57 , Issue.2 , pp. 455-464
    • Ewens, W.J.1    Spielman, R.S.2
  • 33
    • 0038240595 scopus 로고    scopus 로고
    • Genomic approaches to understanding obstructive sleep apnea
    • Palmer L.J., and Redline S. Genomic approaches to understanding obstructive sleep apnea. Respir Physiol Neurobiol 135 2-3 (2003) 187-205
    • (2003) Respir Physiol Neurobiol , vol.135 , Issue.2-3 , pp. 187-205
    • Palmer, L.J.1    Redline, S.2
  • 34
    • 4744372082 scopus 로고    scopus 로고
    • Evolution of the Fgf and Fgfr gene families
    • Itoh N., and Ornitz D.M. Evolution of the Fgf and Fgfr gene families. Trends Genet 20 11 (2004) 563-569
    • (2004) Trends Genet , vol.20 , Issue.11 , pp. 563-569
    • Itoh, N.1    Ornitz, D.M.2
  • 35
    • 0842279779 scopus 로고    scopus 로고
    • Skeletal development is regulated by fibroblast growth factor receptor 1 signalling dynamics
    • Hajihosseini M.K., Lalioti M.D., Arthaud S., Burgar H.R., Brown J.M., Twigg S.R., et al. Skeletal development is regulated by fibroblast growth factor receptor 1 signalling dynamics. Development 131 2 (2004) 325-335
    • (2004) Development , vol.131 , Issue.2 , pp. 325-335
    • Hajihosseini, M.K.1    Lalioti, M.D.2    Arthaud, S.3    Burgar, H.R.4    Brown, J.M.5    Twigg, S.R.6
  • 36
    • 28444453646 scopus 로고    scopus 로고
    • Growth of the normal skull vault and its alteration in craniosynostosis: insights from human genetics and experimental studies
    • Morriss-Kay G.M., and Wilkie A.O. Growth of the normal skull vault and its alteration in craniosynostosis: insights from human genetics and experimental studies. J Anat 207 5 (2005) 637-653
    • (2005) J Anat , vol.207 , Issue.5 , pp. 637-653
    • Morriss-Kay, G.M.1    Wilkie, A.O.2
  • 37
    • 23444441294 scopus 로고    scopus 로고
    • Genetic determinants of upper airway structures that predispose to obstructive sleep apnea
    • Schwab R.J. Genetic determinants of upper airway structures that predispose to obstructive sleep apnea. Respir Physiol Neurobiol 147 2-3 (2005) 289-298
    • (2005) Respir Physiol Neurobiol , vol.147 , Issue.2-3 , pp. 289-298
    • Schwab, R.J.1
  • 38
    • 2342644820 scopus 로고    scopus 로고
    • Genome-wide linkage to chromosome 6 for waist circumference in the Framingham heart study
    • Fox C.S., Heard-Costa N.L., Wilson P.W., Levy D., D'Agostino Sr. R.B., and Atwood L.D. Genome-wide linkage to chromosome 6 for waist circumference in the Framingham heart study. Diabetes 53 5 (2004) 1399-1402
    • (2004) Diabetes , vol.53 , Issue.5 , pp. 1399-1402
    • Fox, C.S.1    Heard-Costa, N.L.2    Wilson, P.W.3    Levy, D.4    D'Agostino Sr., R.B.5    Atwood, L.D.6
  • 39
    • 0037422843 scopus 로고    scopus 로고
    • Genetic variation in the renin-angiotensin system and abdominal adiposity in men: the olivetti prospective heart study
    • Strazzullo P., Iacone R., Iacoviello L., Russo O., Barba G., Russo P., et al. Genetic variation in the renin-angiotensin system and abdominal adiposity in men: the olivetti prospective heart study. Ann Intern Med 138 1 (2003) 17-23
    • (2003) Ann Intern Med , vol.138 , Issue.1 , pp. 17-23
    • Strazzullo, P.1    Iacone, R.2    Iacoviello, L.3    Russo, O.4    Barba, G.5    Russo, P.6
  • 40
    • 0035516048 scopus 로고    scopus 로고
    • Gly40Ser polymorphism of the glucagon receptor gene is associated with central adiposity in men
    • Siani A., Iacone R., Russo O., Barba G., Russo P., Cappuccio F.P., et al. Gly40Ser polymorphism of the glucagon receptor gene is associated with central adiposity in men. Obes Res 9 11 (2001) 722-726
    • (2001) Obes Res , vol.9 , Issue.11 , pp. 722-726
    • Siani, A.1    Iacone, R.2    Russo, O.3    Barba, G.4    Russo, P.5    Cappuccio, F.P.6
  • 41
    • 0035120211 scopus 로고    scopus 로고
    • A genome-wide scan for abdominal fat assessed by computed tomography in the Quebec family study
    • Perusse L., Rice T., Chagnon Y.C., Despres J.P., Lemieux S., Roy S., et al. A genome-wide scan for abdominal fat assessed by computed tomography in the Quebec family study. Diabetes 50 3 (2001) 614-621
    • (2001) Diabetes , vol.50 , Issue.3 , pp. 614-621
    • Perusse, L.1    Rice, T.2    Chagnon, Y.C.3    Despres, J.P.4    Lemieux, S.5    Roy, S.6
  • 42
    • 33646271627 scopus 로고    scopus 로고
    • Evidence for a role of developmental genes in the origin of obesity and body fat distribution
    • Gesta S., Bluher M., Yamamoto Y., Norris A.W., Berndt J., Kralisch S., et al. Evidence for a role of developmental genes in the origin of obesity and body fat distribution. Proc Natl Acad Sci USA 103 17 (2006) 6676-6681
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.17 , pp. 6676-6681
    • Gesta, S.1    Bluher, M.2    Yamamoto, Y.3    Norris, A.W.4    Berndt, J.5    Kralisch, S.6
  • 45
    • 0036146384 scopus 로고    scopus 로고
    • A novel heterozygous mutation in peroxisome proliferator-activated receptor-gamma gene in a patient with familial partial lipodystrophy
    • Agarwal A.K., and Garg A. A novel heterozygous mutation in peroxisome proliferator-activated receptor-gamma gene in a patient with familial partial lipodystrophy. J Clin Endocrinol Metab 87 1 (2002) 408-411
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.1 , pp. 408-411
    • Agarwal, A.K.1    Garg, A.2
  • 46
    • 28944446431 scopus 로고    scopus 로고
    • The many faces of PPAR gamma
    • Lehrke M., and Lazar M.A. The many faces of PPAR gamma. Cell 123 6 (2005) 993-999
    • (2005) Cell , vol.123 , Issue.6 , pp. 993-999
    • Lehrke, M.1    Lazar, M.A.2
  • 47
    • 0036894397 scopus 로고    scopus 로고
    • PPARG F388L, a transactivation-deficient mutant, in familial partial lipodystrophy
    • Hegele R.A., Cao H., Frankowski C., Mathews S.T., and Leff T. PPARG F388L, a transactivation-deficient mutant, in familial partial lipodystrophy. Diabetes 51 12 (2002) 3586-3590
    • (2002) Diabetes , vol.51 , Issue.12 , pp. 3586-3590
    • Hegele, R.A.1    Cao, H.2    Frankowski, C.3    Mathews, S.T.4    Leff, T.5
  • 48
    • 8744247436 scopus 로고    scopus 로고
    • A single-base mutation in the peroxisome proliferator-activated receptor gamma4 promoter associated with altered in vitro expression and partial lipodystrophy
    • Al-Shali K., Cao H., Knoers N., Hermus A.R., Tack C.J., and Hegele R.A. A single-base mutation in the peroxisome proliferator-activated receptor gamma4 promoter associated with altered in vitro expression and partial lipodystrophy. J Clin Endocrinol Metab 89 11 (2004) 5655-5660
    • (2004) J Clin Endocrinol Metab , vol.89 , Issue.11 , pp. 5655-5660
    • Al-Shali, K.1    Cao, H.2    Knoers, N.3    Hermus, A.R.4    Tack, C.J.5    Hegele, R.A.6
  • 49
  • 50
    • 33745291825 scopus 로고    scopus 로고
    • The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over 6 years and combines with the effect of the APM1 G-11391A single nucleotide polymorphism: the data from an epidemiological study on the insulin resistance syndrome (DESIR) study
    • Jaziri R., Lobbens S., Aubert R., Pean F., Lahmidi S., Vaxillaire M., et al. The PPARG Pro12Ala polymorphism is associated with a decreased risk of developing hyperglycemia over 6 years and combines with the effect of the APM1 G-11391A single nucleotide polymorphism: the data from an epidemiological study on the insulin resistance syndrome (DESIR) study. Diabetes 55 4 (2006) 1157-1162
    • (2006) Diabetes , vol.55 , Issue.4 , pp. 1157-1162
    • Jaziri, R.1    Lobbens, S.2    Aubert, R.3    Pean, F.4    Lahmidi, S.5    Vaxillaire, M.6
  • 53
    • 0023020183 scopus 로고
    • The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations
    • Baron R.M., and Kenny D.A. The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Pers Soc Psychol 51 6 (1986) 1173-1182
    • (1986) J Pers Soc Psychol , vol.51 , Issue.6 , pp. 1173-1182
    • Baron, R.M.1    Kenny, D.A.2
  • 54
    • 0037387365 scopus 로고    scopus 로고
    • Does accounting for gene-environment (G × E) interaction increase the power to detect the effect of a gene in a multifactorial disease?
    • Selinger-Leneman H., Genin E., Norris J.M., and Khlat M. Does accounting for gene-environment (G × E) interaction increase the power to detect the effect of a gene in a multifactorial disease?. Genet Epidemiol 24 3 (2003) 200-207
    • (2003) Genet Epidemiol , vol.24 , Issue.3 , pp. 200-207
    • Selinger-Leneman, H.1    Genin, E.2    Norris, J.M.3    Khlat, M.4
  • 55
    • 0031442493 scopus 로고    scopus 로고
    • Effects of genotype-by-sex interaction on quantitative trait linkage analysis
    • Towne B., Siervogel R.M., and Blangero J. Effects of genotype-by-sex interaction on quantitative trait linkage analysis. Genet Epidemiol 14 6 (1997) 1053-1058
    • (1997) Genet Epidemiol , vol.14 , Issue.6 , pp. 1053-1058
    • Towne, B.1    Siervogel, R.M.2    Blangero, J.3
  • 56
    • 0030056295 scopus 로고    scopus 로고
    • Genetic and environmental correlations among hormone levels and measures of body fat accumulation and topography
    • Comuzzie A.G., Blangero J., Mahaney M.C., Haffner S.M., Mitchell B.D., Stern M.P., et al. Genetic and environmental correlations among hormone levels and measures of body fat accumulation and topography. J Clin Endocrinol Metab 81 2 (1996) 597-600
    • (1996) J Clin Endocrinol Metab , vol.81 , Issue.2 , pp. 597-600
    • Comuzzie, A.G.1    Blangero, J.2    Mahaney, M.C.3    Haffner, S.M.4    Mitchell, B.D.5    Stern, M.P.6
  • 58
    • 79959503826 scopus 로고    scopus 로고
    • The international HapMap project. Nature 2003; 426 (6968): 789-96.
  • 59
    • 0034799051 scopus 로고    scopus 로고
    • Candidate genes and single nucleotide polymorphisms (SNPs) in the study of human disease
    • Chanock S. Candidate genes and single nucleotide polymorphisms (SNPs) in the study of human disease. Dis Markers 17 2 (2001) 89-98
    • (2001) Dis Markers , vol.17 , Issue.2 , pp. 89-98
    • Chanock, S.1
  • 60
    • 33744813831 scopus 로고    scopus 로고
    • Analysing the effect of candidate genes on complex traits: an application in multiple sclerosis
    • Hooper-van Veen T., Berkhof J., Polman C.H., and Uitdehaag B.M. Analysing the effect of candidate genes on complex traits: an application in multiple sclerosis. Immunogenetics (2006)
    • (2006) Immunogenetics
    • Hooper-van Veen, T.1    Berkhof, J.2    Polman, C.H.3    Uitdehaag, B.M.4
  • 61
    • 0034660559 scopus 로고    scopus 로고
    • Searching for genetic determinants in the new millennium
    • Risch N.J. Searching for genetic determinants in the new millennium. Nature 405 6788 (2000) 847-856
    • (2000) Nature , vol.405 , Issue.6788 , pp. 847-856
    • Risch, N.J.1
  • 62
    • 24644518521 scopus 로고    scopus 로고
    • Association of apolipoprotein E4 and haplotypes of the apolipoprotein E gene with lobar intracerebral hemorrhage
    • Woo D., Kaushal R., Chakraborty R., Woo J., Haverbusch M., Sekar P., et al. Association of apolipoprotein E4 and haplotypes of the apolipoprotein E gene with lobar intracerebral hemorrhage. Stroke 36 9 (2005) 1874-1879
    • (2005) Stroke , vol.36 , Issue.9 , pp. 1874-1879
    • Woo, D.1    Kaushal, R.2    Chakraborty, R.3    Woo, J.4    Haverbusch, M.5    Sekar, P.6
  • 63
    • 0032957882 scopus 로고    scopus 로고
    • Risk factors for sleep-disordered breathing in children. Associations with obesity, race, and respiratory problems
    • Redline S., Tishler P.V., Schluchter M., Aylor J., Clark K., and Graham G. Risk factors for sleep-disordered breathing in children. Associations with obesity, race, and respiratory problems. Am J Respir Crit Care Med 159 5 Pt 1 (1999) 1527-1532
    • (1999) Am J Respir Crit Care Med , vol.159 , Issue.5 PART 1 , pp. 1527-1532
    • Redline, S.1    Tishler, P.V.2    Schluchter, M.3    Aylor, J.4    Clark, K.5    Graham, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.