Site-directed mutagenesis identifies active-site residues of the light chain of botulinum neurotoxin type A

Biochemical and Biophysical Research Communications

Volumn 288, Issue 5, 2001, Pages 1231-1237

  Rigoni, Michela ^a   Caccin, Paola ^a   Johnson, Eric A ^b   Montecucco, Cesare ^a   Rossetto, Ornella ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF WISCONSIN   (United States)

Author keywords

Active site; Botulinum neurotoxin type A; Recombinant protein; Site directed mutagenesis

Indexed keywords

BOTULINUM TOXIN A; BOTULINUM TOXIN B; GLUTAMINE; PHENYLALANINE; SNARE PROTEIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; TYROSINE; ZINC;

ARTICLE; CATALYSIS; EXOCYTOSIS; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; TOXIN ANALYSIS;

EID: 0035900618     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5911     Document Type: Article

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