메뉴 건너뛰기




Volumn 28, Issue 3, 2007, Pages 636-642

Central infusion of the melanocortin receptor antagonist agouti-related peptide (AgRP(83-132)) prevents cachexia-related symptoms induced by radiation and colon-26 tumors in mice

Author keywords

AgRP; Anorexia; Cytokine; Feeding; Melanocortin; Tumor

Indexed keywords

AGOUTI RELATED PROTEIN; MELANOCORTIN RECEPTOR;

EID: 33846807457     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2006.11.021     Document Type: Article
Times cited : (52)

References (43)
  • 1
    • 0032583131 scopus 로고    scopus 로고
    • Central injection in rats of alpha-melanocyte-stimulating hormone analog: effects on food intake and brain Fos
    • Brown K.S., Gentry R.M., and Rowland N.E. Central injection in rats of alpha-melanocyte-stimulating hormone analog: effects on food intake and brain Fos. Regul Pept 78 (1998) 89-94
    • (1998) Regul Pept , vol.78 , pp. 89-94
    • Brown, K.S.1    Gentry, R.M.2    Rowland, N.E.3
  • 2
    • 17844401704 scopus 로고    scopus 로고
    • Anatomy and regulation of the central melanocortin system
    • Cone R.D. Anatomy and regulation of the central melanocortin system. Nat Neurosci 8 (2005) 571-578
    • (2005) Nat Neurosci , vol.8 , pp. 571-578
    • Cone, R.D.1
  • 4
    • 0018949428 scopus 로고
    • Prognostic effect of weight loss prior to chemotherapy in cancer patients. Eastern Cooperative Oncology Group
    • Dewys W.D., Begg C., Lavin P.T., Band P.R., Bennett J.M., Bertino J.R., et al. Prognostic effect of weight loss prior to chemotherapy in cancer patients. Eastern Cooperative Oncology Group. Am J Med 69 (1980) 491-497
    • (1980) Am J Med , vol.69 , pp. 491-497
    • Dewys, W.D.1    Begg, C.2    Lavin, P.T.3    Band, P.R.4    Bennett, J.M.5    Bertino, J.R.6
  • 5
  • 7
    • 0642364431 scopus 로고    scopus 로고
    • Acute intracerebroventricular administration of either carboxyl-terminal or amino-terminal fragments of agouti-related peptide produces a long-term decrease in energy expenditure in rats
    • Goto K., Inui A., Takimoto Y., Yuzuriha H., Asakawa A., Kawamura Y., et al. Acute intracerebroventricular administration of either carboxyl-terminal or amino-terminal fragments of agouti-related peptide produces a long-term decrease in energy expenditure in rats. Int J Mol Med 12 (2003) 379-383
    • (2003) Int J Mol Med , vol.12 , pp. 379-383
    • Goto, K.1    Inui, A.2    Takimoto, Y.3    Yuzuriha, H.4    Asakawa, A.5    Kawamura, Y.6
  • 8
    • 0032400808 scopus 로고    scopus 로고
    • Brainstem application of melanocortin receptor ligands produces long-lasting effects on feeding and body weight
    • Grill H.J., Ginsberg A.B., Seeley R.J., and Kaplan J.M. Brainstem application of melanocortin receptor ligands produces long-lasting effects on feeding and body weight. J Neurosci 18 (1998) 10128-10135
    • (1998) J Neurosci , vol.18 , pp. 10128-10135
    • Grill, H.J.1    Ginsberg, A.B.2    Seeley, R.J.3    Kaplan, J.M.4
  • 11
    • 0032949410 scopus 로고    scopus 로고
    • Role of central melanocortins in endotoxin-induced anorexia
    • Huang Q.H., Hruby V.J., and Tatro J.B. Role of central melanocortins in endotoxin-induced anorexia. Am J Physiol 276 (1999) R864-R871
    • (1999) Am J Physiol , vol.276
    • Huang, Q.H.1    Hruby, V.J.2    Tatro, J.B.3
  • 12
    • 27144453045 scopus 로고    scopus 로고
    • Central administration of peptide and small molecule MC4 receptor antagonists induce hyperphagia in mice and attenuate cytokine-induced anorexia
    • Joppa M.A., Ling N., Chen C., Gogas K.R., Foster A.C., and Markison S. Central administration of peptide and small molecule MC4 receptor antagonists induce hyperphagia in mice and attenuate cytokine-induced anorexia. Peptides 26 (2005) 2294-2301
    • (2005) Peptides , vol.26 , pp. 2294-2301
    • Joppa, M.A.1    Ling, N.2    Chen, C.3    Gogas, K.R.4    Foster, A.C.5    Markison, S.6
  • 13
  • 14
    • 0242320429 scopus 로고    scopus 로고
    • Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10
    • Krude H., Biebermann H., Schnabel D., Tansek M.Z., Theunissen P., Mullis P.E., et al. Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10. J Clin Endocrinol Metab 88 (2003) 4633-4640
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4633-4640
    • Krude, H.1    Biebermann, H.2    Schnabel, D.3    Tansek, M.Z.4    Theunissen, P.5    Mullis, P.E.6
  • 15
    • 0034985788 scopus 로고    scopus 로고
    • Anorexic but not pyrogenic actions of interleukin-1 are modulated by central melanocortin-3/4 receptors in the rat
    • Lawrence C.B., and Rothwell N.J. Anorexic but not pyrogenic actions of interleukin-1 are modulated by central melanocortin-3/4 receptors in the rat. J Neuroendocrinol 13 (2001) 490-495
    • (2001) J Neuroendocrinol , vol.13 , pp. 490-495
    • Lawrence, C.B.1    Rothwell, N.J.2
  • 17
    • 18844432794 scopus 로고    scopus 로고
    • The regulation of feeding and metabolic rate and the prevention of murine cancer cachexia with a small-molecule melanocortin-4 receptor antagonist
    • Markison S., Foster A.C., Chen C., Brookhart G.B., Hesse A., Hoare S.R., et al. The regulation of feeding and metabolic rate and the prevention of murine cancer cachexia with a small-molecule melanocortin-4 receptor antagonist. Endocrinology 146 (2005) 2766-2773
    • (2005) Endocrinology , vol.146 , pp. 2766-2773
    • Markison, S.1    Foster, A.C.2    Chen, C.3    Brookhart, G.B.4    Hesse, A.5    Hoare, S.R.6
  • 18
    • 0035866377 scopus 로고    scopus 로고
    • Role of the central melanocortin system in cachexia
    • Marks D.L., Ling N., and Cone R.D. Role of the central melanocortin system in cachexia. Cancer Res 61 (2001) 1432-1438
    • (2001) Cancer Res , vol.61 , pp. 1432-1438
    • Marks, D.L.1    Ling, N.2    Cone, R.D.3
  • 21
    • 10744228966 scopus 로고    scopus 로고
    • Increased serum levels of interleukin-6 in malnourished patients with colorectal cancer
    • Nakagoe T., Tsuji T., Sawai T., Tanaka K., Hidaka S., Shibasaki S., et al. Increased serum levels of interleukin-6 in malnourished patients with colorectal cancer. Cancer Lett 202 (2003) 109-115
    • (2003) Cancer Lett , vol.202 , pp. 109-115
    • Nakagoe, T.1    Tsuji, T.2    Sawai, T.3    Tanaka, K.4    Hidaka, S.5    Shibasaki, S.6
  • 22
    • 0034753891 scopus 로고    scopus 로고
    • Hypothalamic appetite-regulating neuropeptide mRNA levels in cachectic nude mice bearing human tumor cells
    • Nara-Ashizawa N., Tsukada T., Maruyama K., Akiyama Y., Kajimura N., Nagasaki K., et al. Hypothalamic appetite-regulating neuropeptide mRNA levels in cachectic nude mice bearing human tumor cells. Metabolism 50 (2001) 1213-1219
    • (2001) Metabolism , vol.50 , pp. 1213-1219
    • Nara-Ashizawa, N.1    Tsukada, T.2    Maruyama, K.3    Akiyama, Y.4    Kajimura, N.5    Nagasaki, K.6
  • 23
    • 0035822275 scopus 로고    scopus 로고
    • Role of cytokines in cancer cachexia in a murine model of intracerebral injection of human tumours
    • Negri D.R., Mezzanzanica D., Sacco S., Gadina M., Benigni F., Cajola L., et al. Role of cytokines in cancer cachexia in a murine model of intracerebral injection of human tumours. Cytokine 15 (2001) 27-38
    • (2001) Cytokine , vol.15 , pp. 27-38
    • Negri, D.R.1    Mezzanzanica, D.2    Sacco, S.3    Gadina, M.4    Benigni, F.5    Cajola, L.6
  • 24
    • 33645889660 scopus 로고    scopus 로고
    • Peripheral administration of a melanocortin 4-receptor inverse agonist prevents loss of lean body mass in tumor-bearing mice
    • Nicholson J.R., Kohler G., Schaerer F., Senn C., Weyermann P., and Hofbauer K.G. Peripheral administration of a melanocortin 4-receptor inverse agonist prevents loss of lean body mass in tumor-bearing mice. J Pharmacol Exp Ther 317 (2006) 771-777
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 771-777
    • Nicholson, J.R.1    Kohler, G.2    Schaerer, F.3    Senn, C.4    Weyermann, P.5    Hofbauer, K.G.6
  • 26
    • 0030764741 scopus 로고    scopus 로고
    • Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
    • Ollmann M.M., Wilson B.D., Yang Y.K., Kerns J.A., Chen Y., Gantz I., et al. Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science 278 (1997) 135-138
    • (1997) Science , vol.278 , pp. 135-138
    • Ollmann, M.M.1    Wilson, B.D.2    Yang, Y.K.3    Kerns, J.A.4    Chen, Y.5    Gantz, I.6
  • 28
    • 0033771667 scopus 로고    scopus 로고
    • Central nervous system mechanisms contributing to the cachexia-anorexia syndrome
    • Plata-Salaman C.R. Central nervous system mechanisms contributing to the cachexia-anorexia syndrome. Nutrition 16 (2000) 1009-1012
    • (2000) Nutrition , vol.16 , pp. 1009-1012
    • Plata-Salaman, C.R.1
  • 29
    • 0031844188 scopus 로고    scopus 로고
    • Brain cytokine mRNAs in anorectic rats bearing prostate adenocarcinoma tumor cells
    • Plata-Salaman C.R., Ilyin S.E., and Gayle D. Brain cytokine mRNAs in anorectic rats bearing prostate adenocarcinoma tumor cells. Am J Physiol 275 (1998) R566-R573
    • (1998) Am J Physiol , vol.275
    • Plata-Salaman, C.R.1    Ilyin, S.E.2    Gayle, D.3
  • 30
    • 15144357684 scopus 로고    scopus 로고
    • A C-terminal fragment of Agouti-related protein increases feeding and antagonizes the effect of alpha-melanocyte stimulating hormone in vivo
    • Rossi M., Kim M.S., Morgan D.G., Small C.J., Edwards C.M., Sunter D., et al. A C-terminal fragment of Agouti-related protein increases feeding and antagonizes the effect of alpha-melanocyte stimulating hormone in vivo. Endocrinology 139 (1998) 4428-4431
    • (1998) Endocrinology , vol.139 , pp. 4428-4431
    • Rossi, M.1    Kim, M.S.2    Morgan, D.G.3    Small, C.J.4    Edwards, C.M.5    Sunter, D.6
  • 31
    • 0035142129 scopus 로고    scopus 로고
    • Effects of chronic central nervous system administration of agouti-related protein in pair-fed animals
    • Small C.J., Kim M.S., Stanley S.A., Mitchell J.R., Murphy K., Morgan D.G., et al. Effects of chronic central nervous system administration of agouti-related protein in pair-fed animals. Diabetes 50 (2001) 248-254
    • (2001) Diabetes , vol.50 , pp. 248-254
    • Small, C.J.1    Kim, M.S.2    Stanley, S.A.3    Mitchell, J.R.4    Murphy, K.5    Morgan, D.G.6
  • 33
    • 0026689535 scopus 로고
    • Evidence for the involvement of interleukin 6 in experimental cancer cachexia
    • Strassmann G., Fong M., Kenney J.S., and Jacob C.O. Evidence for the involvement of interleukin 6 in experimental cancer cachexia. J Clin Invest 89 (1992) 1681-1684
    • (1992) J Clin Invest , vol.89 , pp. 1681-1684
    • Strassmann, G.1    Fong, M.2    Kenney, J.S.3    Jacob, C.O.4
  • 34
    • 0025263860 scopus 로고
    • Experimental cancer cachexia induced by transplantable colon 26 adenocarcinoma in mice
    • Tanaka Y., Eda H., Tanaka T., Udagawa T., Ishikawa T., Horii I., et al. Experimental cancer cachexia induced by transplantable colon 26 adenocarcinoma in mice. Cancer Res 50 (1990) 2290-2295
    • (1990) Cancer Res , vol.50 , pp. 2290-2295
    • Tanaka, Y.1    Eda, H.2    Tanaka, T.3    Udagawa, T.4    Ishikawa, T.5    Horii, I.6
  • 35
    • 0036830917 scopus 로고    scopus 로고
    • Cachexia in cancer patients
    • Tisdale M.J. Cachexia in cancer patients. Nat Rev Cancer 2 (2002) 862-871
    • (2002) Nat Rev Cancer , vol.2 , pp. 862-871
    • Tisdale, M.J.1
  • 36
    • 0031662163 scopus 로고    scopus 로고
    • A frameshift mutation in human MC4R is associated with a dominant form of obesity
    • Vaisse C., Clement K., Guy-Grand B., and Froguel P. A frameshift mutation in human MC4R is associated with a dominant form of obesity. Nat Genet 20 (1998) 113-114
    • (1998) Nat Genet , vol.20 , pp. 113-114
    • Vaisse, C.1    Clement, K.2    Guy-Grand, B.3    Froguel, P.4
  • 37
    • 27144519937 scopus 로고    scopus 로고
    • The causes and consequences of cancer-associated malnutrition
    • Van Cutsem E., and Arends J. The causes and consequences of cancer-associated malnutrition. Eur J Oncol Nurs 9 Suppl 2 (2005) S51-S63
    • (2005) Eur J Oncol Nurs , vol.9 , Issue.SUPPL. 2
    • Van Cutsem, E.1    Arends, J.2
  • 38
    • 12144285830 scopus 로고    scopus 로고
    • Identification of 2-[2-[2-(5-bromo-2-methoxyphenyl)-ethyl]-3-fluorophenyl]-4,5-dihydro-1H-imidazole (ML00253764), a small molecule melanocortin 4 receptor antagonist that effectively reduces tumor-induced weight loss in a mouse model
    • Vos T.J., Caracoti A., Che J.L., Dai M., Farrer C.A., Forsyth N.E., et al. Identification of 2-[2-[2-(5-bromo-2-methoxyphenyl)-ethyl]-3-fluorophenyl]-4,5-dihydro-1H-imidazole (ML00253764), a small molecule melanocortin 4 receptor antagonist that effectively reduces tumor-induced weight loss in a mouse model. J Med Chem 47 (2004) 1602-1604
    • (2004) J Med Chem , vol.47 , pp. 1602-1604
    • Vos, T.J.1    Caracoti, A.2    Che, J.L.3    Dai, M.4    Farrer, C.A.5    Forsyth, N.E.6
  • 39
    • 0037457669 scopus 로고    scopus 로고
    • Expression of the human cachexia-associated protein (HCAP) in prostate cancer and in a prostate cancer animal model of cachexia
    • Wang Z., Corey E., Hass G.M., Higano C.S., True L.D., Wallace Jr. D., et al. Expression of the human cachexia-associated protein (HCAP) in prostate cancer and in a prostate cancer animal model of cachexia. Int J Cancer 105 (2003) 123-129
    • (2003) Int J Cancer , vol.105 , pp. 123-129
    • Wang, Z.1    Corey, E.2    Hass, G.M.3    Higano, C.S.4    True, L.D.5    Wallace Jr., D.6
  • 40
    • 0033790824 scopus 로고    scopus 로고
    • Agouti-related protein in the hypothalamic paraventricular nucleus: effect on feeding
    • Wirth M.M., and Giraudo S.Q. Agouti-related protein in the hypothalamic paraventricular nucleus: effect on feeding. Peptides 21 (2000) 1369-1375
    • (2000) Peptides , vol.21 , pp. 1369-1375
    • Wirth, M.M.1    Giraudo, S.Q.2
  • 42
    • 1442324342 scopus 로고    scopus 로고
    • Hypothalamic melanocortin system regulates sympathetic nerve activity in brown adipose tissue
    • Yasuda T., Masaki T., Kakuma T., and Yoshimatsu H. Hypothalamic melanocortin system regulates sympathetic nerve activity in brown adipose tissue. Exp Biol Med (Maywood) 229 (2004) 235-239
    • (2004) Exp Biol Med (Maywood) , vol.229 , pp. 235-239
    • Yasuda, T.1    Masaki, T.2    Kakuma, T.3    Yoshimatsu, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.