Unanticipated differences between α- and γ-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates

Nucleic Acids Research

Volumn 35, Issue 1, 2007, Pages 307-316

  Tsai, Sherry M ^b   Farkas, Michelle E ^b   Chou, C James ^a   Gottesfeld, Joel M ^a   Dervan, Peter B ^b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b California Institute of Technology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CHLORAMBUCIL; CHLORAMBUCIL DERIVATIVE; CHLORAMBUCIL DERIVATIVES; CHLORAMBUCIL POLYAMIDE CONJUGATE; DNA BINDING PROTEIN; POLYAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; COLON CANCER; CONTROLLED STUDY; DNA CLEAVAGE; DRUG DNA BINDING; DRUG STRUCTURE; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; LETHALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ALKYLATING AGENTS; ALKYLATION; AMINOBUTYRIC ACIDS; ANIMALS; BASE SEQUENCE; CELL CYCLE; CELL PROLIFERATION; CHLORAMBUCIL; DNA; FEMALE; HUMANS; MICE; MICE, INBRED BALB C; NYLONS; PLASMIDS; STEREOISOMERISM; TIME FACTORS;

ANIMALIA; MUS;

EID: 33846701129     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkl1025     Document Type: Article

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