DNA crosslinking and biological activity of a hairpin polyamide-chlorambucil conjugate

Nucleic Acids Research

Volumn 31, Issue 4, 2003, Pages 1208-1215

  Wang, Yong Dong ^b   Dziegielewski, Jaroslaw ^b   Wurtz, Nicholas R ^a   Dziegielewska, Barbara ^b   Dervan, Peter B ^b   Beerman, Terry A ^b  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; ALKYLATING AGENT; CHLORAMBUCIL; CYTOSINE; DNA; GUANINE; IMIDAZOLE DERIVATIVE; POLYAMIDE; PYRROLE DERIVATIVE; TYROSINE;

ANIMAL CELL; BINDING SITE; CELL ACTIVITY; CELL CYCLE G2 PHASE; CELL FREE SYSTEM; CELL GROWTH; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA ALKYLATION; DNA CROSS LINKING; DNA DAMAGE; DNA REPLICATION; DNA TEMPLATE; DRUG ACTIVITY; DRUG CONJUGATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; INHIBITION KINETICS; MAMMAL CELL; MITOSIS INHIBITION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVIEW; SIMIAN VIRUS 40; VIRUS REPLICATION;

ALKYLATION; ANIMALS; BASE SEQUENCE; BINDING SITES; CELL CYCLE; CELL DIVISION; CHLORAMBUCIL; CROSS-LINKING REAGENTS; DNA; DNA REPLICATION; DNA, VIRAL; HELA CELLS; HUMANS; JURKAT CELLS; MOLECULAR STRUCTURE; NYLONS; PROTEIN BIOSYNTHESIS; PROTEINS; RNA; SIMIAN VIRUS 40; TUMOR CELLS, CULTURED;

ANIMALIA; MAMMALIA; SIMIAE; SIMIAN VIRUS 40;

EID: 0037440726     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkg215     Document Type: Review

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