-
2
-
-
0141757460
-
MAPK pathways in radiation responses
-
Dent P, Yacoub A, Fisher PB, Hagan MP, Grant S: MAPK pathways in radiation responses. Oncogene 22: 5885-96, 2003
-
(2003)
Oncogene
, vol.22
, pp. 5885-5896
-
-
Dent, P.1
Yacoub, A.2
Fisher, P.B.3
Hagan, M.P.4
Grant, S.5
-
3
-
-
0027813823
-
MAP kinase kinase: A node connecting multiple pathways
-
Mordret G: MAA kinase kinase: a node connecting multiple pathways. Biol Cell 79: 193-207, 1993
-
(1993)
Biol Cell
, vol.79
, pp. 193-207
-
-
Mordret, G.1
-
4
-
-
0028926263
-
Parallel signal processing among mammalian MAPKs
-
Cano E, Mahadevan LC: Parallel signal processing among mammalian MAPKs. Trends Biochem Sci 20: 117-122, 1995
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 117-122
-
-
Cano, E.1
Mahadevan, L.C.2
-
6
-
-
0034045949
-
Inhibition of p38 MAP kinase as a therapeutic strategy
-
Lee JC, Kumar S, Griswold DE, Underwood DC, Votta BJ, Adams JL: Inhibition of p38 MAP kinase as a therapeutic strategy. Immunopharmacology 47: 185-201, 2000
-
(2000)
Immunopharmacology
, vol.47
, pp. 185-201
-
-
Lee, J.C.1
Kumar, S.2
Griswold, D.E.3
Underwood, D.C.4
Votta, B.J.5
Adams, J.L.6
-
7
-
-
0035787526
-
Ras activation of the Raf kinase: Tyrosine kinase recruitment of the MAP kinase cascade
-
Avruch J, Khokhlatchev A, Kyriakis JM, Luo Z, Tzivion G, Vavvas D, Zhang XF: Ras activation of the RaT kinase: tyrosine kinase recruitment of the MAP kinase cascade. Recent Prog Horm Res 56: 127-155, 2001
-
(2001)
Recent Prog Horm Res
, vol.56
, pp. 127-155
-
-
Avruch, J.1
Khokhlatchev, A.2
Kyriakis, J.M.3
Luo, Z.4
Tzivion, G.5
Vavvas, D.6
Zhang, X.F.7
-
8
-
-
0035072954
-
G-protein-mediated signaling and its control in macrophages and mammalian cells
-
Chakraborty P: G-protein-mediated signaling and its control in macrophages and mammalian cells. Crit Rev Microbiol 27: 1-8, 2001
-
(2001)
Crit Rev Microbiol
, vol.27
, pp. 1-8
-
-
Chakraborty, P.1
-
9
-
-
0035952645
-
New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades
-
Pierce KL, Luttrell LM, Lefkowitz RJ: New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades. Oncogene 20: 1532-1539, 2001
-
(2001)
Oncogene
, vol.20
, pp. 1532-1539
-
-
Pierce, K.L.1
Luttrell, L.M.2
Lefkowitz, R.J.3
-
10
-
-
0037340102
-
Interleukin-10 and the regulation of mitogen-activated protein kinases: Are these signalling modules targets for the anti-inflammatory action of this cytokine?
-
Haddad JJ, Saade NE, Safieh-Garabedian B: Interleukin-10 and the regulation of mitogen-activated protein kinases: Are these signalling modules targets for the anti-inflammatory action of this cytokine? Cell Signal 15: 255-267, 2003
-
(2003)
Cell Signal
, vol.15
, pp. 255-267
-
-
Haddad, J.J.1
Saade, N.E.2
Safieh-Garabedian, B.3
-
11
-
-
0242361581
-
Transcriptional regulation by the MAP kinase signaling cascades
-
Yang SH, Sharrocks AD, Whitmarsh AJ: Transcriptional regulation by the MAP kinase signaling cascades. Gene 320: 3-21, 2003
-
(2003)
Gene
, vol.320
, pp. 3-21
-
-
Yang, S.H.1
Sharrocks, A.D.2
Whitmarsh, A.J.3
-
12
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis JM, Avruch J: Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 81: 807-869, 2001
-
(2001)
Physiol Rev
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
13
-
-
0036709020
-
Fidelity and spatio-temporal control in MAP kinase (ERKs) signaling
-
Pouyssegur J, Volmat V, Lenormand P: Fidelity and spatio-temporal control in MAP kinase (ERKs) signaling. Biochem Pharmacol 64: 755-763, 2002
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 755-763
-
-
Pouyssegur, J.1
Volmat, V.2
Lenormand, P.3
-
14
-
-
0029257329
-
Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines
-
Alessi DR, Gomez N, Moorhead G, Lewis T, Keyse SM, Cohen P: Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines. Current Biol 5: 283-295, 1995
-
(1995)
Current Biol
, vol.5
, pp. 283-295
-
-
Alessi, D.R.1
Gomez, N.2
Moorhead, G.3
Lewis, T.4
Keyse, S.M.5
Cohen, P.6
-
15
-
-
0033970533
-
Dual specificity phosphatases: A gene family for control of MAP kinase function
-
Camps M, Nichols A, ArkinAtall S: Dual specificity phosphatases: a gene family for control of MAP kinase function. FASEB J 14: 6-16, 2000
-
(2000)
FASEB J
, vol.14
, pp. 6-16
-
-
Camps, M.1
Nichols, A.2
Arkinstall, S.3
-
16
-
-
0034096201
-
Protein phosphatases and the regulation of mitogen-activated protein kinase signaling
-
Keyse SM: Protein phosphatases and the regulation of mitogen-activated protein kinase signaling. Current Opinion in Cell Biology 12: 186-192, 2000
-
(2000)
Current Opinion in Cell Biology
, vol.12
, pp. 186-192
-
-
Keyse, S.M.1
-
17
-
-
0036165251
-
Pharmacological inhibitors of MAPK pathways
-
English JM, Cobb MH: Pharmacological inhibitors of MAPK pathways. Trends Pharmacol Sci 23: 40-45, 2002
-
(2002)
Trends Pharmacol Sci
, vol.23
, pp. 40-45
-
-
English, J.M.1
Cobb, M.H.2
-
18
-
-
0034059884
-
Signal transduction and cellular radiation responses
-
Schmidt-Ullrich RK, Dent P, Grant S, Mikkelsen RB, Valerie K: Signal transduction and cellular radiation responses. Radiat Res 153: 245-257, 2000
-
(2000)
Radiat Res
, vol.153
, pp. 245-257
-
-
Schmidt-Ullrich, R.K.1
Dent, P.2
Grant, S.3
Mikkelsen, R.B.4
Valerie, K.5
-
19
-
-
0036718590
-
MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells
-
Shonai T, Adachi M, Sakata K, Takekawa M, Endo T, Imai K, Hareyama M: MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells. Cell Death Differ 9: 963-971, 2002
-
(2002)
Cell Death Differ
, vol.9
, pp. 963-971
-
-
Shonai, T.1
Adachi, M.2
Sakata, K.3
Takekawa, M.4
Endo, T.5
Imai, K.6
Hareyama, M.7
-
20
-
-
0033568419
-
Coordinated regulation of radioadaptive response by protein kinase C and p38 mitogen-activated protein kinase
-
Shimizu T, Kato Jr T, Tachibana A, Sasaki MS: Coordinated regulation of radioadaptive response by protein kinase C and p38 mitogen-activated protein kinase. Exp Cell Res 251: 424-432, 1999
-
(1999)
Exp Cell Res
, vol.251
, pp. 424-432
-
-
Shimizu, T.1
Kato Jr., T.2
Tachibana, A.3
Sasaki, M.S.4
-
21
-
-
0035887492
-
Indomethacin-induced radiosensitization and inhibition of ionizing radiation-induced NF-kappaB activation in HeLa cells occur via a mechanism involving p38 MAP kinase
-
Bradbury CM, Markovina S, Wei SJ, Rene LM, Zoberi I, Horikoshi N, Gius D: Indomethacin-induced radiosensitization and inhibition of ionizing radiation-induced NF-kappaB activation in HeLa cells occur via a mechanism involving p38 MAP kinase. Cancer Res 61: 7689-7696, 2001
-
(2001)
Cancer Res
, vol.61
, pp. 7689-7696
-
-
Bradbury, C.M.1
Markovina, S.2
Wei, S.J.3
Rene, L.M.4
Zoberi, I.5
Horikoshi, N.6
Gius, D.7
-
22
-
-
0038485982
-
PKC epsilon-mediated ERK1/2 activation involved in radiation-induced cell death in NIH3T3 cells
-
Lee YJ, Soh JW, Jeoung DI, Cho CK, Jhon GJ, Lee SJ, Lee YS: PKC epsilon-mediated ERK1/2 activation involved in radiation-induced cell death in NIH3T3 cells. Biochim Biophys Acta 1593: 219-229, 2003
-
(2003)
Biochim Biophys Acta
, vol.1593
, pp. 219-229
-
-
Lee, Y.J.1
Soh, J.W.2
Jeoung, D.I.3
Cho, C.K.4
Jhon, G.J.5
Lee, S.J.6
Lee, Y.S.7
-
23
-
-
1642383850
-
mda-7 (IL-24) Inhibits growth and enhances radiosensitivity of glioma cells in vitro via JNK signaling
-
Yacoub A, Mitchell C, Lebedeva IV, Sarkar D, Su ZZ, McKinstry R, Gopalkrishnan RV, Grant S, Fisher PB, Dent P: Mda-7 (IL-24) Inhibits growth and enhances radiosensitivity of glioma cells in vitro via JNK signaling. Cancer Biol Ther 2: 347-353, 2003
-
(2003)
Cancer Biol Ther
, vol.2
, pp. 347-353
-
-
Yacoub, A.1
Mitchell, C.2
Lebedeva, I.V.3
Sarkar, D.4
Su, Z.Z.5
McKinstry, R.6
Gopalkrishnan, R.V.7
Grant, S.8
Fisher, P.B.9
Dent, P.10
-
24
-
-
7344237348
-
Ex vivo evidence for asymmetric tyrosine phosphorylation of ZAP-70 on double-positive thymocytes in the positive selection process
-
Kametani Y, Goto H, Kobori A, Sato T, Ando K, Hozumi K, Nishimura T, Saito T, Yamamoto T, Habu S: Ex vivo evidence for asymmetric tyrosine phosphorylation of ZAP-70 on double-positive thymocytes in the positive selection process. Int Immunol 10: 1203-1210, 1998
-
(1998)
Int Immunol
, vol.10
, pp. 1203-1210
-
-
Kametani, Y.1
Goto, H.2
Kobori, A.3
Sato, T.4
Ando, K.5
Hozumi, K.6
Nishimura, T.7
Saito, T.8
Yamamoto, T.9
Habu, S.10
-
25
-
-
1842732175
-
Inositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activity
-
Wen BG, Pletcher MT, Warashina M, Choe SH, Ziaee N, Wiltshire T, Sauer K, Cooke MP: Inositol (1,4,5) trisphosphate 3 kinase B controls positive selection of T cells and modulates Erk activity. Proc Natl Acad Sci USA 101: 5604-5609, 2004
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 5604-5609
-
-
Wen, B.G.1
Pletcher, M.T.2
Warashina, M.3
Choe, S.H.4
Ziaee, N.5
Wiltshire, T.6
Sauer, K.7
Cooke, M.P.8
-
26
-
-
0034698112
-
Ultraviolet light-induced stimulation of the JNK mitogen-activated protein kinase in the absence of src family tyrosine kinase activation
-
Amdjadi K, Sefton BM: Ultraviolet light-induced stimulation of the JNK mitogen-activated protein kinase in the absence of src family tyrosine kinase activation. J Biol Chem 275: 22520-22525, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 22520-22525
-
-
Amdjadi, K.1
Sefton, B.M.2
-
27
-
-
0035895980
-
Inhibitory role for dual specificity phosphatase VHR in T cell antigen receptor and CD28-induced Erk and Jnk activation
-
Alonso A, Saxena M, Williams S, Mustelin T: Inhibitory role for dual specificity phosphatase VHR in T cell antigen receptor and CD28-induced Erk and Jnk activation. J Biol Chem 276: 4766-4771, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 4766-4771
-
-
Alonso, A.1
Saxena, M.2
Williams, S.3
Mustelin, T.4
-
28
-
-
0033563010
-
Alkyl-lysophospholipids activate the SAPK/JNK pathway and enhance radiation-induced apoptosis
-
Ruiter GA, Zerp SF, Bartelink H, van Blitterswijk WJ, Verheij M: Alkyl-lysophospholipids activate the SAPK/JNK pathway and enhance radiation-induced apoptosis. Cancer Res 59: 2457-2463, 1999
-
(1999)
Cancer Res
, vol.59
, pp. 2457-2463
-
-
Ruiter, G.A.1
Zerp, S.F.2
Bartelink, H.3
van Blitterswijk, W.J.4
Verheij, M.5
-
29
-
-
0034909113
-
2-induced ERK1/2 phosphorylation without the requirement for MEK1/2 phosphorylation
-
2-induced ERK1/2 phosphorylation without the requirement for MEK1/2 phosphorylation. Cell Signal 13: 645-652, 2001
-
(2001)
Cell Signal
, vol.13
, pp. 645-652
-
-
Lee, K.1
Esselman, W.J.2
-
30
-
-
0032013322
-
Lipopolysaccharide-induced NF-kappaB activation and cytokine release in human alveolar macrophages is PKC-independent and TK- and PC-PLC-dependent
-
Carter AB, Monick MM, Hunninghake GW: Lipopolysaccharide-induced NF-kappaB activation and cytokine release in human alveolar macrophages is PKC-independent and TK- and PC-PLC-dependent. Am J Respir Cell Mol Biol 18: 384-391, 1998
-
(1998)
Am J Respir Cell Mol Biol
, vol.18
, pp. 384-391
-
-
Carter, A.B.1
Monick, M.M.2
Hunninghake, G.W.3
-
31
-
-
0028141973
-
Radiation induction of immediate early genes: Effectors of the radiation-stress response
-
Weichselbaum RR, Hallahan D, Fuks Z, Kufe D: Radiation induction of immediate early genes: Effectors of the radiation-stress response. Int J Radiat Oncol Biol Phys 30: 229-234, 1994
-
(1994)
Int J Radiat Oncol Biol Phys
, vol.30
, pp. 229-234
-
-
Weichselbaum, R.R.1
Hallahan, D.2
Fuks, Z.3
Kufe, D.4
-
32
-
-
0037382977
-
Dose-dependent differential expression of protein kinase C isozymes in mouse lymphocytes after gamma irradiation in vivo and ex vivo
-
Varadkar PA, Krishna M, Verma NC: Dose-dependent differential expression of protein kinase C isozymes in mouse lymphocytes after gamma irradiation in vivo and ex vivo. Radiat Res 159: 453-457, 2003
-
(2003)
Radiat Res
, vol.159
, pp. 453-457
-
-
Varadkar, P.A.1
Krishna, M.2
Verma, N.C.3
-
33
-
-
0037146797
-
Ex vivo isolation protocols differentially affect the phenotype of human CD4+ T cells
-
Bernard F, Jaleco S, Dardalhon V, Steinberg M, Yssel H, Noraz N, Taylor N, Kinet S: Ex vivo isolation protocols differentially affect the phenotype of human CD4+ T cells. J Immunol Methods 271: 99-106, 2002
-
(2002)
J Immunol Methods
, vol.271
, pp. 99-106
-
-
Bernard, F.1
Jaleco, S.2
Dardalhon, V.3
Steinberg, M.4
Yssel, H.5
Noraz, N.6
Taylor, N.7
Kinet, S.8
-
34
-
-
0032575135
-
Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose ionizing radiation in A431 human squamous carcinoma cells
-
Carter S, Auer KL, Reardon DB, Birrer M, Fisher PB, Valerie K, Schmidt-Ullrich R, Mikkelsen R, Dent P: Inhibition of the mitogen activated protein (MAP) kinase cascade potentiates cell killing by low dose ionizing radiation in A431 human squamous carcinoma cells. Oncogene 16: 2787-2796, 1998
-
(1998)
Oncogene
, vol.16
, pp. 2787-2796
-
-
Carter, S.1
Auer, K.L.2
Reardon, D.B.3
Birrer, M.4
Fisher, P.B.5
Valerie, K.6
Schmidt-Ullrich, R.7
Mikkelsen, R.8
Dent, P.9
-
35
-
-
0032780627
-
Inhibition of the MAPK pathway abrogates BCL2-mediated survival of leukemia cells after exposure to low-dose ionizing radiation
-
Vrana JA, Grant S, Dent P: Inhibition of the MAPK pathway abrogates BCL2-mediated survival of leukemia cells after exposure to low-dose ionizing radiation. Radiat Res 151: 559-569, 1999
-
(1999)
Radiat Res
, vol.151
, pp. 559-569
-
-
Vrana, J.A.1
Grant, S.2
Dent, P.3
-
36
-
-
0034997845
-
Mitogen-activated protein (MAP) kinase pathways: Regulation and physiological functions
-
Pearson G, Robinson F, Beers Gibson T, Xu BE, Karandikar M, Berman K, Cobb MH: Mitogen-activated protein (MAP) kiRase pathways: regulation and physiological functions. Endocrine Rev 22: 153-183, 2001
-
(2001)
Endocrine Rev
, vol.22
, pp. 153-183
-
-
Pearson, G.1
Robinson, F.2
Beers Gibson, T.3
Xu, B.E.4
Karandikar, M.5
Berman, K.6
Cobb, M.H.7
-
38
-
-
0035820526
-
Phenoxypyrimidine inhibitors of p38alpha kinase: Synthesis and statistical evaluation of the p38 inhibitory potencies of a series of 1-(piperidin-4-yl)-4-(4-fluorophenyl)-5-(2-phenoxypyrimidin-4-yl) imidazoles
-
Boehm JC, Bower MJ, Gallagher TF, Kassis S, Johnson SR, Adams JL: Phenoxypyrimidine inhibitors of p38alpha kinase: Synthesis and statistical evaluation of the p38 inhibitory potencies of a series of 1-(piperidin-4-yl)-4-(4-fluorophenyl)-5-(2-phenoxypyrimidin-4-yl) imidazoles. Bioorg Med Chem Lett 11: 1123-1126, 2001
-
(2001)
Bioorg Med Chem Lett
, vol.11
, pp. 1123-1126
-
-
Boehm, J.C.1
Bower, M.J.2
Gallagher, T.F.3
Kassis, S.4
Johnson, S.R.5
Adams, J.L.6
-
39
-
-
14444279192
-
Identification of a novel inhibitor of mitogen-activated protein kinase kinase
-
Favata MF, Horiuchi KY, Manos EJ, Daulerio AJ, Stradley DA, Feeser WS, Van Dyk DE, Pitts WJ, Earl RA, Hobbs F, Copeland RA, Magolda RL, Scherle PA, Trzaskos JM: Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chemi 273: 18623-18632, 1998
-
(1998)
J Biol Chemi
, vol.273
, pp. 18623-18632
-
-
Favata, M.F.1
Horiuchi, K.Y.2
Manos, E.J.3
Daulerio, A.J.4
Stradley, D.A.5
Feeser, W.S.6
Van Dyk, D.E.7
Pitts, W.J.8
Earl, R.A.9
Hobbs, F.10
Copeland, R.A.11
Magolda, R.L.12
Scherle, P.A.13
Trzaskos, J.M.14
-
40
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies SP, Reddy H, Caivano M, Cohen P: Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem J 351: 95-105, 2000
-
(2000)
Biochem J
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
41
-
-
0034931503
-
c-Jun N- terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis
-
Han Z, Boyle DL, Chang L, Bennett B, Karin M, Yang L, Manning AM, Firestein GS: C-Jun N- terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis. J Clin Invest 108: 73-81, 2001
-
(2001)
J Clin Invest
, vol.108
, pp. 73-81
-
-
Han, Z.1
Boyle, D.L.2
Chang, L.3
Bennett, B.4
Karin, M.5
Yang, L.6
Manning, A.M.7
Firestein, G.S.8
|