Epidemiological dynamics of antimonial resistance in Leishmania donovani: Genotyping reveals a polyclonal population structure among naturally-resistant clinical isolates from Nepal

Infection, Genetics and Evolution

Volumn 7, Issue 2, 2007, Pages 206-212

  Laurent, Thierry ^a   Rijal, Suman ^b   Yardley, Vanessa ^c   Croft, Simon ^c   De Doncker, Simonne ^a   Decuypere, Saskia ^a,f   Khanal, Basudha ^b   Singh, Rupa ^b   Schönian, Gabriele ^d   Kuhls, Katrin ^d   Chappuis, François ^e   Dujardin, Jean Claude ^a  

^a INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^b B P KOIRALA INSTITUTE OF HEALTH SCIENCES   (Nepal)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^e GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^f UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Antimony resistance; Kala Azar; kDNA; Leishmania donovani; Microsatellite; Population structure

Indexed keywords

AMPHOTERICIN B DEOXYCHOLATE; ANTIMONY GLUCONATE; MINICIRCLE DNA;

ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; DRUG SENSITIVITY; EPIDEMIOLOGICAL DATA; GENOTYPE; HUMAN; IN VITRO STUDY; INFECTION RESISTANCE; LEISHMANIA DONOVANI; MICROSATELLITE MARKER; NEPAL; NONHUMAN; PARASITE ISOLATION; POLYCLONAL ACTIVATION; POLYMERASE CHAIN REACTION; POPULATION STRUCTURE; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; VISCERAL LEISHMANIASIS;

AMPHOTERICIN B; ANIMALS; ANTIPROTOZOAL AGENTS; BONE MARROW; DNA, KINETOPLAST; DRUG RESISTANCE; GENOTYPE; HUMANS; LEISHMANIA DONOVANI; LEISHMANIASIS, VISCERAL; NEPAL; PHYLOGENY; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH;

LEISHMANIA DONOVANI; NASO HEXACANTHUS;

EID: 33846567493     PISSN: 15671348     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.meegid.2006.08.005     Document Type: Article

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