Guide RNAs of the recently isolated LEM125 strain of Leishmania tarentolae: An unexpected complexity

RNA

Volumn 7, Issue 9, 2001, Pages 1335-1347

  Gao, Guanghan ^a   Kapushoc, Stephen T ^a   Simpson, Agda M ^a   Thiemann, Otavio H ^b   Simpson, Larry ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Leishmania tarentolae; Minicircle classes; Redundant guide RNAs; RNA editing

Indexed keywords

GUIDE RNA; MITOCHONDRIAL DNA;

ARTICLE; DNA SEQUENCE; LEISHMANIA TARENTOLAE; MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA EDITING; RNA SEQUENCE; STRAIN DIFFERENCE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DNA, KINETOPLAST; LEISHMANIA; MOLECULAR SEQUENCE DATA; RNA, GUIDE; RNA, PROTOZOAN; SEQUENCE ALIGNMENT;

LEISHMANIA TARENTOLAE; PROTOZOA; TRYPANOSOMATIDAE;

EID: 0034853642     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1355838201018076     Document Type: Article

References (32)

1. Isolation and characterization of a U-specific 3′-5′ exonuclease from mitochondria of Leishmania tarentolae
2. A model for RNA editing in kinetoplastid mitochondria: "Guide" RNA molecules transcribed from maxicircle DNA provide the edited information
3. Guide RNAs in kinetoplastid mitochondria have a nonencoded 3′ oligo-(U) tail involved in recognition of the pre-edited region
4. Isolation of kinetoplast-mitochondrial complexes from Leishmania tarentolae
5. Trypanosoma brucei minicircles encode multiple guide RNAs which can direct editing of extensively overlapping sequences
6. Trypanosoma brucei mitochondrial CR4 gene encodes an extensively edited mRNA with completely edited sequence only in bloodstream forms
7. Trypanosome U-deletional RNA editing involves guide RNA-directed endonuclease cleavage, terminal U exonuclease, and RNA ligase activities
8. Uridine insertion/deletion RNA editing in trypanosome mitochondria - A review
9. Translation of the edited mRNA for cytochrome b in trypanosome mitochondria
10. RNA editing: A mechanism for gRNA-specified uridylate insertion into precursor mRNA
11. Sequence heterogeneity and anomalous electrophoretic mobility of kinetoplast minicircle DNA in Leishmania tarentolae
12. A bent helix in kinetoplast DNA
13. The polarity of editing within a multiple gRNA-mediated domain is due to formation of anchors for upstream gRNAs by downstream editing
14. Identification of candidate mitochondrial RNA editing ligases from Trypanosoma brucei
15. Disruption of a gene encoding a novel mitochondrial DEAD-box protein in Trypanosoma brucei affects edited mRNAs
16. A gap at a unique location in newly replicated kinetoplast DNA minicircles from Trypanosoma equiperdum
17. Conserved sequence blocks in kinetoplast DNA minicircles from diverse species of trypanosomes
18. Extensive editing of both processed and preprocessed maxicircle CR6 transcripts in Trypanosoma brucei
19. Editing of Trypanosoma brucei maxicircle CR5 mRNA generates variable carboxy terminal predicted protein sequences
20. The two RNA ligases of the Trypanosoma brucei RNA editing complex: Cloning the essential band IV gene and identifying the band V gene
21. A theoretical study of random segregation of minicircles in trypanosomatids
22. Redundant and non-functional guide RNA genes in Trypanosoma brucei are a consequence of multiple genes per minicircle
23. An RNA ligase essential for RNA editing and survival of the bloodstream form of Trypanosoma brucei
24. Direct visualization of uridylate deletion in vitro suggests a mechanism for kinetoplastid RNA editing
25. Isolation of maxicircle component of kinetoplast DNA from hemoflagellate protozoa
26. The mitochondrial genome of kinetoplastid protozoa: Genomic organization, transcription, replication and evolution
27. Kinetoplast RNA from Leishmania tarentolae
28. Evolution of RNA editing in trypanosome mitochondria
29. Maxicircle CR1 transcripts of Trypanosoma brucei are edited, developmentally regulated, and encode a putative iron-sulfur protein homologous to an NADH dehydrogenase subunit
30. Extensive editing of CR2 maxicircle transcripts of Trypanosoma brucei predicts a protein with homology to a subunit of NADH dehydrogenase
31. Leishmania tarentolae minicircles of different sequence classes encode single guide RNAs located in the variable region approximately 150 bp from the conserved region
32. Disruption of RNA editing in Leishmania tarentolae by the loss of minicircle-encoded guide RNA genes