메뉴 건너뛰기




Volumn 5, Issue 1, 2007, Pages 119-124

β-adrenergic pathways in human heart failure

Author keywords

adrenergic; CaMKII; cAMP; Fetal gene program; PDE3; Phospholamban; PKA PP1; Receptors

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA 3 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CYCLIC AMP; ENOXIMONE; PHOSPHODIESTERASE III; PHOSPHODIESTERASE III INHIBITOR; PHOSPHOLAMBAN; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR; PROTEIN KINASE (CALCIUM,CALMODULIN) II; PROTEIN KINASE INHIBITOR;

EID: 33846554749     PISSN: 14779072     EISSN: 17448344     Source Type: Journal    
DOI: 10.1586/14779072.5.1.119     Document Type: Review
Times cited : (18)

References (53)
  • 1
    • 0032938219 scopus 로고    scopus 로고
    • Left ventricular hypertrophy in hypertension: Stimuli, patterns, and consequences
    • Devereux RB, Roman MJ. Left ventricular hypertrophy in hypertension: stimuli, patterns, and consequences. Hypertens Res. 22(1), 1-9 (1999).
    • (1999) Hypertens Res. , vol.22 , Issue.1 , pp. 1-9
    • Devereux, R.B.1    Roman, M.J.2
  • 2
    • 0035979382 scopus 로고    scopus 로고
    • Differential effects of angiotensin II versus endothelin-1 inhibitions in hypertrophic left ventricular myocardium during transition to heart failure
    • Iwanaga Y, Kihara Y, Inagaki K et al. Differential effects of angiotensin II versus endothelin-1 inhibitions in hypertrophic left ventricular myocardium during transition to heart failure. Circulation 104(5), 606-612 (2001).
    • (2001) Circulation , vol.104 , Issue.5 , pp. 606-612
    • Iwanaga, Y.1    Kihara, Y.2    Inagaki, K.3
  • 3
    • 0027043314 scopus 로고
    • Left ventricular shape is the primary determinant of functional mitral regurgitation in heart failure
    • Kono T, Sabbah HN, Rosman H, Alam M, Jafri S, Goldstein S. Left ventricular shape is the primary determinant of functional mitral regurgitation in heart failure. J. Am. Coll. Cardiol. 20(7), 1594-1598 (1992).
    • (1992) J. Am. Coll. Cardiol. , vol.20 , Issue.7 , pp. 1594-1598
    • Kono, T.1    Sabbah, H.N.2    Rosman, H.3    Alam, M.4    Jafri, S.5    Goldstein, S.6
  • 5
    • 0030660245 scopus 로고    scopus 로고
    • Mechanism of action of β-blocking agents in heart failure
    • Bristow MR. Mechanism of action of β-blocking agents in heart failure. Am. J. Cardiol. 80(11A), 26L-40L (1997).
    • (1997) Am. J. Cardiol. , vol.80 , Issue.11 A
    • Bristow, M.R.1
  • 7
    • 0037007679 scopus 로고    scopus 로고
    • Myocardial gene expression in dilated cardiomyopathy treated with β-blocking agents
    • Lowes BD, Gilbert EM, Abraham WT et al. Myocardial gene expression in dilated cardiomyopathy treated with β-blocking agents. N. Engl. J. Med. 346(18), 1357-1365 (2002).
    • (2002) N. Engl. J. Med. , vol.346 , Issue.18 , pp. 1357-1365
    • Lowes, B.D.1    Gilbert, E.M.2    Abraham, W.T.3
  • 8
    • 24044495268 scopus 로고    scopus 로고
    • Mechanisms of disease: β-adrenergic receptors - Alterations in signal transduction and pharmacogenomics in heart failure
    • Feldman DS, Carnes CA, Abraham WT, Bristow MR. Mechanisms of disease: β-adrenergic receptors - alterations in signal transduction and pharmacogenomics in heart failure. Nat. Clin. Pract. Cardiovasc. Med. 2(9), 475-483 (2005).
    • (2005) Nat. Clin. Pract. Cardiovasc. Med. , vol.2 , Issue.9 , pp. 475-483
    • Feldman, D.S.1    Carnes, C.A.2    Abraham, W.T.3    Bristow, M.R.4
  • 9
    • 33644865929 scopus 로고    scopus 로고
    • Compartmentalized phosphodiesterase-2 activity blunts β-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway
    • Mongillo M, Tocchetti CG, Terrin A et al. Compartmentalized phosphodiesterase-2 activity blunts β-adrenergic cardiac inotropy via an NO/cGMP-dependent pathway. Circ. Res. 98(2), 226-234 (2006).
    • (2006) Circ. Res. , vol.98 , Issue.2 , pp. 226-234
    • Mongillo, M.1    Tocchetti, C.G.2    Terrin, A.3
  • 10
    • 0034978329 scopus 로고    scopus 로고
    • β-adrenergic cardiac hypertrophy is mediated primarily by the β(1)-subtype in the rat heart
    • Morisco C, Zebrowski DC, Vatner DE, Vatner SF, Sadoshima J. β-adrenergic cardiac hypertrophy is mediated primarily by the β(1)-subtype in the rat heart. J. Mol. Cell. Cardiol. 33(3), 561-573 (2001).
    • (2001) J. Mol. Cell. Cardiol. , vol.33 , Issue.3 , pp. 561-573
    • Morisco, C.1    Zebrowski, D.C.2    Vatner, D.E.3    Vatner, S.F.4    Sadoshima, J.5
  • 11
    • 0036859163 scopus 로고    scopus 로고
    • The β-adrenergic receptors
    • Wallukat G. The β-adrenergic receptors. Herz 27(7), 683-690 (2002).
    • (2002) Herz , vol.27 , Issue.7 , pp. 683-690
    • Wallukat, G.1
  • 12
    • 0042316928 scopus 로고    scopus 로고
    • Protein kinase A and G protein-coupled receptor kinase phosphorylation mediates β-1 adrenergic receptor endocytosis through different pathways
    • Rapacciuolo A, Suvarna S, Barki-Harrington L et al. Protein kinase A and G protein-coupled receptor kinase phosphorylation mediates β-1 adrenergic receptor endocytosis through different pathways. J. Biol. Chem. 278(37), 35403-35411 (2003).
    • (2003) J. Biol. Chem. , vol.278 , Issue.37 , pp. 35403-35411
    • Rapacciuolo, A.1    Suvarna, S.2    Barki-Harrington, L.3
  • 13
    • 33846473544 scopus 로고    scopus 로고
    • Adrenergic Receptor Coupling and uncoupling in heart failure
    • In: Richard A. Walsh (Ed.)
    • Port JD BM. Adrenergic Receptor Coupling and uncoupling in heart failure. In: Richard A. Walsh (Ed.). Molecular Mechanism for Cardiac Hypertrophy and Failure, 323-340.
    • Molecular Mechanism for Cardiac Hypertrophy and Failure , pp. 323-340
    • Port, J.D.B.M.1
  • 14
    • 0347357650 scopus 로고    scopus 로고
    • Decreased protein and phosphorylation level of the protein phosphatase inhibitor-1 in failing human hearts
    • El-Armouche A, Pamminger T, Ditz D, Zolk O, Eschenhagen T. Decreased protein and phosphorylation level of the protein phosphatase inhibitor-1 in failing human hearts. Cardiovasc. Res. 61(1), 87-93 (2004).
    • (2004) Cardiovasc. Res. , vol.61 , Issue.1 , pp. 87-93
    • El-Armouche, A.1    Pamminger, T.2    Ditz, D.3    Zolk, O.4    Eschenhagen, T.5
  • 15
    • 25144446880 scopus 로고    scopus 로고
    • Alterations in cAMP-mediated signaling and their role in the pathophysiology of dilated cardiomyopathy
    • Movsesian MA, Bristow MR. Alterations in cAMP-mediated signaling and their role in the pathophysiology of dilated cardiomyopathy. Curr. Top. Dev. Biol. 68, 25-48 (2005).
    • (2005) Curr. Top. Dev. Biol. , vol.68 , pp. 25-48
    • Movsesian, M.A.1    Bristow, M.R.2
  • 16
    • 0242637601 scopus 로고    scopus 로고
    • What is the role of β-adrenergic signaling in heart failure?
    • Lohse MJ, Engelhardt S, Eschenhagen T. What is the role of β-adrenergic signaling in heart failure? Circ. Res. 93(10), 896-906 (2003).
    • (2003) Circ. Res. , vol.93 , Issue.10 , pp. 896-906
    • Lohse, M.J.1    Engelhardt, S.2    Eschenhagen, T.3
  • 17
    • 0032698819 scopus 로고    scopus 로고
    • β-adrenergic receptor agonists and cyclic nucleotide phosphodiesterase inhibitors: Shifting the focus from inotropy to cyclic adenosine monophosphate
    • Movsesian MA. β-adrenergic receptor agonists and cyclic nucleotide phosphodiesterase inhibitors: Shifting the focus from inotropy to cyclic adenosine monophosphate. J. Am. Coll. Cardiol. 34(2), 318-324 (1999).
    • (1999) J. Am. Coll. Cardiol. , vol.2 , Issue.34 , pp. 318-324
    • Movsesian, M.A.1
  • 18
    • 26644467896 scopus 로고    scopus 로고
    • Clinical trials update from the European Society of Cardiology meeting 2005: CARE-HF extension study, ESSENTIAL, CIBIS-III, S-ICD, ISSUE-2, STRIDE-2, SOFA, IMAGINE, PREAMI, SIRIUS-II and ACTIVE
    • Cleland JG, Coletta AP, Lammiman M et al. Clinical trials update from the European Society of Cardiology meeting 2005: CARE-HF extension study, ESSENTIAL, CIBIS-III, S-ICD, ISSUE-2, STRIDE-2, SOFA, IMAGINE, PREAMI, SIRIUS-II and ACTIVE. Eur. J. Heart Fail. 7(6), 1070-1075 (2005).
    • (2005) Eur. J. Heart Fail. , vol.7 , Issue.6 , pp. 1070-1075
    • Cleland, J.G.1    Coletta, A.P.2    Lammiman, M.3
  • 20
    • 21044453725 scopus 로고    scopus 로고
    • Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: Implication in heart failure
    • Ding B, Abe J, Wei H et al. Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: Implication in heart failure. Circulation 111(19), 2469-2476 (2005).
    • (2005) Circulation , vol.111 , Issue.19 , pp. 2469-2476
    • Ding, B.1    Abe, J.2    Wei, H.3
  • 21
    • 26844504704 scopus 로고    scopus 로고
    • A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis
    • Ding B, Abe J, Wei H et al. A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis. Proc. Natl Acad. Sci. USA 102(41), 14771-14776 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , Issue.41 , pp. 14771-14776
    • Ding, B.1    Abe, J.2    Wei, H.3
  • 22
    • 9344234405 scopus 로고    scopus 로고
    • Adrenergic regulation of ICER (inducible cyclic AMP early repressor) and β1-adrenergic receptor gene expression in C6 glioma cells
    • Fitzgerald LR, Li Z, Machida CA, Fishman PH, Duman RS. Adrenergic regulation of ICER (inducible cyclic AMP early repressor) and β1-adrenergic receptor gene expression in C6 glioma cells. J. Neurochem. 67(2), 490-497 (1996).
    • (1996) J. Neurochem. , vol.67 , Issue.2 , pp. 490-497
    • Fitzgerald, L.R.1    Li, Z.2    Machida, C.A.3    Fishman, P.H.4    Duman, R.S.5
  • 23
    • 0031722958 scopus 로고    scopus 로고
    • Phospholamban: Protein structure, mechanism of action, and role in cardiac function
    • Simmerman HK, Jones LR. Phospholamban: Protein structure, mechanism of action, and role in cardiac function. Physiol. Rev. 78(4), 921-947 (1998).
    • (1998) Physiol. Rev. , vol.78 , Issue.4 , pp. 921-947
    • Simmerman, H.K.1    Jones, L.R.2
  • 24
    • 6344258936 scopus 로고    scopus 로고
    • 2+/calmodulin kinase signaling pathway
    • 2+/calmodulin kinase signaling pathway. Circ. Res. 95(8), 798-806 (2004).
    • (2004) Circ. Res. , vol.95 , Issue.8 , pp. 798-806
    • Wang, W.1    Zhu, W.2    Wang, S.3
  • 25
    • 0032897465 scopus 로고    scopus 로고
    • 2+/calmodulin- dependent protein kinase in failing and nonfailing human hearts
    • 2+/calmodulin-dependent protein kinase in failing and nonfailing human hearts. Cardiovasc. Res. 42(1), 254-261 (1999).
    • (1999) Cardiovasc. Res. , vol.42 , Issue.1 , pp. 254-261
    • Kirchhefer, U.1    Schmitz, W.2    Scholz, H.3    Neumann, J.4
  • 27
    • 0030888810 scopus 로고    scopus 로고
    • Increased expression of cardiac phosphatases in patients with end-stage heart failure
    • Neumann J, Eschenhagen T, Jones LR et al. Increased expression of cardiac phosphatases in patients with end-stage heart failure. J. Mol. Cell. Cardiol. 29(1), 265-272 (1997).
    • (1997) J. Mol. Cell. Cardiol. , vol.29 , Issue.1 , pp. 265-272
    • Neumann, J.1    Eschenhagen, T.2    Jones, L.R.3
  • 28
    • 0344009618 scopus 로고    scopus 로고
    • Cardiac SR-coupled PP1 activity and expression are increased and inhibitor 1 protein expression is decreased in failing hearts
    • Gupta RC, Mishra S, Rastogi S, Imai M, Habib O, Sabbah HN. Cardiac SR-coupled PP1 activity and expression are increased and inhibitor 1 protein expression is decreased in failing hearts. Am J. Physiol. Heart Circ. Physiol. 285(6), H2373-H2381 (2003).
    • (2003) Am J. Physiol. Heart Circ. Physiol. , vol.285 , Issue.6
    • Gupta, R.C.1    Mishra, S.2    Rastogi, S.3    Imai, M.4    Habib, O.5    Sabbah, H.N.6
  • 29
    • 24344499138 scopus 로고    scopus 로고
    • Enhanced cardiac function in mice overexpressing protein phosphatase Inhibitor-2
    • Kirchhefer U, Baba HA, Boknik P et al. Enhanced cardiac function in mice overexpressing protein phosphatase Inhibitor-2. Cardiovasc. Res. 68(1), 98-108 (2005).
    • (2005) Cardiovasc. Res. , vol.68 , Issue.1 , pp. 98-108
    • Kirchhefer, U.1    Baba, H.A.2    Boknik, P.3
  • 30
    • 33845611066 scopus 로고    scopus 로고
    • Inhibition of protein phosphatase 1 by inhibitor-2 gene delivery ameliorates heart failure progression in genetic cardiomyopathy
    • Yamada M, Ikeda Y, Yano M et al. Inhibition of protein phosphatase 1 by inhibitor-2 gene delivery ameliorates heart failure progression in genetic cardiomyopathy. Faseb J. 20(8), 1197-1199 (2006).
    • (2006) Faseb J. , vol.20 , Issue.8 , pp. 1197-1199
    • Yamada, M.1    Ikeda, Y.2    Yano, M.3
  • 31
    • 33846543640 scopus 로고    scopus 로고
    • Long-term β1-adrenergic modulation of cardiac contractility via calmodulin kinase II signaling pathway
    • Wang W, Wang S, Zhu W, Xiao R, Cheng H. Long-term β1-adrenergic modulation of cardiac contractility via calmodulin kinase II signaling pathway. Supplement to Circulation 108(17), 1 (2003).
    • (2003) Supplement to Circulation , vol.108 , Issue.17 , pp. 1
    • Wang, W.1    Wang, S.2    Zhu, W.3    Xiao, R.4    Cheng, H.5
  • 33
    • 20244362095 scopus 로고    scopus 로고
    • Calmodulin kinase II inhibition protects against structural heart disease
    • Zhang R, Khoo MS, Wu Y et al. Calmodulin kinase II inhibition protects against structural heart disease. Nat. Med. 11(4), 409-417 (2005).
    • (2005) Nat. Med. , vol.11 , Issue.4 , pp. 409-417
    • Zhang, R.1    Khoo, M.S.2    Wu, Y.3
  • 34
    • 0028917370 scopus 로고
    • The multifunctional calcium/calmodulin-dependent protein kinase: From form to a function
    • Braun AP, Schulman H. The multifunctional calcium/calmodulin-dependent protein kinase: From form to a function. Annu. Rev. Physiol. 57, 417-445 (1995).
    • (1995) Annu. Rev. Physiol. , vol.57 , pp. 417-445
    • Braun, A.P.1    Schulman, H.2
  • 35
    • 4744343507 scopus 로고    scopus 로고
    • Regulation of calcium/calmodulin-dependent protein kinase II activation by intramolecular and intermolecular interactions
    • Griffith LC. Regulation of calcium/calmodulin-dependent protein kinase II activation by intramolecular and intermolecular interactions. J. Neurosci. 24(39), 8394-8398 (2004).
    • (2004) J. Neurosci. , vol.24 , Issue.39 , pp. 8394-8398
    • Griffith, L.C.1
  • 36
    • 0038643573 scopus 로고    scopus 로고
    • The δC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure
    • Zhang T, Maier LS, Dalton ND et al. The δC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure. Circ. Res. 92(8), 912-9 (2003).
    • (2003) Circ. Res. , vol.92 , Issue.8 , pp. 912-919
    • Zhang, T.1    Maier, L.S.2    Dalton, N.D.3
  • 37
    • 0037059791 scopus 로고    scopus 로고
    • 2+/ calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity
    • 2+/calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity. J. Biol. Chem. 277(2), 1261-7 (2002).
    • (2002) J. Biol. Chem. , vol.277 , Issue.2 , pp. 1261-1267
    • Zhang, T.1    Johnson, E.N.2    Gu, Y.3
  • 38
    • 0033515617 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent protein kinase in failing and nonfailing human myocardium
    • 2+/ calmodulin-dependent protein kinase in failing and nonfailing human myocardium. Circ. Res. 84(6), 713-721 (1999).
    • (1999) Circ. Res. , vol.84 , Issue.6 , pp. 713-721
    • Hoch, B.1    Meyer, R.2    Hetzer, R.3    Krause, E.G.4    Karczewski, P.5
  • 39
    • 0025772161 scopus 로고
    • Unique phosphorylation site on the cardiac ryanodine receptor regulates calcium channel activity
    • Witcher DR, Kovacs RJ, Schulman H, Cefali DC, Jones LR. Unique phosphorylation site on the cardiac ryanodine receptor regulates calcium channel activity. J. Biol. Chem. 266(17), 11144-11152 (1991).
    • (1991) J. Biol. Chem. , vol.266 , Issue.17 , pp. 11144-11152
    • Witcher, D.R.1    Kovacs, R.J.2    Schulman, H.3    Cefali, D.C.4    Jones, L.R.5
  • 40
    • 0028918056 scopus 로고
    • Phosphorylation modulates the function of the calcium release channel of sarcoplasmic reticulum from cardiac muscle
    • Hain J, Onoue H, Mayrleitner M, Fleischer S, Schindler H. Phosphorylation modulates the function of the calcium release channel of sarcoplasmic reticulum from cardiac muscle. J. Biol. Chem. 270(5), 2074-2081 (1995).
    • (1995) J. Biol. Chem. , vol.270 , Issue.5 , pp. 2074-2081
    • Hain, J.1    Onoue, H.2    Mayrleitner, M.3    Fleischer, S.4    Schindler, H.5
  • 41
    • 0033781028 scopus 로고    scopus 로고
    • Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels
    • Dzhura I, Wu Y, Colbran RJ, Balser JR, Anderson ME. Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels. Nat. Cell Biol. 2(3), 173-177 (2000).
    • (2000) Nat. Cell Biol. , vol.2 , Issue.3 , pp. 173-177
    • Dzhura, I.1    Wu, Y.2    Colbran, R.J.3    Balser, J.R.4    Anderson, M.E.5
  • 42
    • 0022921924 scopus 로고
    • Sequence analysis of phospholamban. Identification of phosphorylation sites and two major structural domains
    • Simmerman HK, Collins JH, Theibert JL, Wegener AD, Jones LR. Sequence analysis of phospholamban. Identification of phosphorylation sites and two major structural domains. J. Biol. Chem. 261(28), 13333-13341 (1986).
    • (1986) J. Biol. Chem. , vol.261 , Issue.28 , pp. 13333-13341
    • Simmerman, H.K.1    Collins, J.H.2    Theibert, J.L.3    Wegener, A.D.4    Jones, L.R.5
  • 43
    • 0018674267 scopus 로고
    • Concerted regulation of cardiac sarcoplasmic reticulum calcium transport by cyclic adenosine monophosphate dependent and calcium-calmodulin-dependent phosphorylations
    • Le Peuch CJ, Haiech J, Demaille JG. Concerted regulation of cardiac sarcoplasmic reticulum calcium transport by cyclic adenosine monophosphate dependent and calcium-calmodulin-dependent phosphorylations. Biochemistry 18 (23), 5150-5157 (1979).
    • (1979) Biochemistry , vol.18 , Issue.231 , pp. 5150-5157
    • Le Peuch, C.J.1    Haiech, J.2    Demaille, J.G.3
  • 44
    • 0036702526 scopus 로고    scopus 로고
    • Calcium, calmodulin, and calcium-calmodulin kinase II: Heartbeat to heartbeat and beyond
    • Maier LS, Bers DM. Calcium, calmodulin, and calcium-calmodulin kinase II: Heartbeat to heartbeat and beyond. J. Mol. Cell. Cardiol. 34(8), 919-939 (2002).
    • (2002) J. Mol. Cell. Cardiol. , vol.34 , Issue.8 , pp. 919-939
    • Maier, L.S.1    Bers, D.M.2
  • 45
    • 2342436686 scopus 로고    scopus 로고
    • Cardiomyocyte calcium and calcium/calmodulin-dependent protein kinase II: Friends or foes?
    • Zhang T, Miyamoto S, Brown JH. Cardiomyocyte calcium and calcium/ calmodulin-dependent protein kinase II: Friends or foes? Recent Prog. Horm. Res. 59, 141-168 (2004).
    • (2004) Recent Prog. Horm. Res. , vol.59 , pp. 141-168
    • Zhang, T.1    Miyamoto, S.2    Brown, J.H.3
  • 46
  • 47
    • 0029666260 scopus 로고    scopus 로고
    • 2+/calmodulin-dependent phosphorylation or by interaction with phospholamban
    • 2+/calmodulin-dependent phosphorylation or by interaction with phospholamban. J. Biol. Chem. 271(24), 14206-14213 (1996).
    • (1996) J. Biol. Chem. , vol.271 , Issue.24 , pp. 14206-14213
    • Odermatt, A.1    Kurzydlowski, K.2    MacLennan, D.H.3
  • 50
    • 0029149020 scopus 로고
    • Isoproterenol infusion induces alterations in expression of hypertrophy-associated genes in rat heart
    • Boluyt MO, Long X, Eschenhagen T et al. Isoproterenol infusion induces alterations in expression of hypertrophy-associated genes in rat heart. Am. J. Physiol. 269(2 Pt 2), H638-H647 (1995).
    • (1995) Am. J. Physiol. , vol.269 , Issue.2 PART 2
    • Boluyt, M.O.1    Long, X.2    Eschenhagen, T.3
  • 51
    • 0035853110 scopus 로고    scopus 로고
    • Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo
    • Rothermel BA, McKinsey TA, Vega RB et al. Myocyte-enriched calcineurin-interacting protein, MCIP1, inhibits cardiac hypertrophy in vivo. Proc. Natl Acad. Sci. USA 98(6), 3328-3333 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , Issue.6 , pp. 3328-3333
    • Rothermel, B.A.1    McKinsey, T.A.2    Vega, R.B.3
  • 52
    • 0029845123 scopus 로고    scopus 로고
    • Medical therapy can improve the biological properties of the chronically failing heart. A new era in the treatment of heart failure
    • Eichhorn EJ, Bristow MR. Medical therapy can improve the biological properties of the chronically failing heart. A new era in the treatment of heart failure. Circulation 94(9), 2285-2296 (1996).
    • (1996) Circulation , vol.94 , Issue.9 , pp. 2285-2296
    • Eichhorn, E.J.1    Bristow, M.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.