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Volumn 25, Issue 4, 2006, Pages 585-592

Effects of silencing of mutant p53 gene in human lung adenocarcinoma cell line Anip973

Author keywords

'Gain of function' effects; Cell cycle; Mutant p53 gene; RNAi; TGF BMP pathway

Indexed keywords

BONE MORPHOGENETIC PROTEIN; COMPLEMENTARY DNA; GROWTH DIFFERENTIATION FACTOR 9; INHIBIN B; INVOLUCRIN; MUTANT PROTEIN; PROTEIN P27; PROTEIN P53; SOMATOMEDIN BINDING PROTEIN 3; TRANSFORMING GROWTH FACTOR BETA;

EID: 33846539661     PISSN: 03929078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (17)

References (30)
  • 1
    • 2342461756 scopus 로고    scopus 로고
    • To die or not to die: How does p53 decide?
    • Slee E.A., O'Connor D.J., Lu X.: To die or not to die: how does p53 decide? Oncogene. 23: 2809-2818, 2004.
    • (2004) Oncogene , vol.23 , pp. 2809-2818
    • Slee, E.A.1    O'Connor, D.J.2    Lu, X.3
  • 2
    • 0036467391 scopus 로고    scopus 로고
    • The p53 and Mdm2 families in cancer
    • Michael D., Oren M.: The p53 and Mdm2 families in cancer. Curr. Opin. Genet. Dev. 12: 53-59, 2002.
    • (2002) Curr. Opin. Genet. Dev , vol.12 , pp. 53-59
    • Michael, D.1    Oren, M.2
  • 3
    • 0034209908 scopus 로고    scopus 로고
    • Loss-of-function genetics in mammalian cells: The p53 tumor suppressor model
    • Carnero A., Hudson J.D., Hannon G.J., Beach D.H. Loss-of-function genetics in mammalian cells: the p53 tumor suppressor model. Nucleic Acids Res. 28: 2234-2241, 2000.
    • (2000) Nucleic Acids Res , vol.28 , pp. 2234-2241
    • Carnero, A.1    Hudson, J.D.2    Hannon, G.J.3    Beach, D.H.4
  • 4
    • 10944236962 scopus 로고    scopus 로고
    • Olive K.P., Tuveson D.A., Ruhe Z.C., Yin B., Willis N.A., Bronson R.T., Crowley D., Jacks T.: Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome. Cell 119: 847-60, 2004.
    • Olive K.P., Tuveson D.A., Ruhe Z.C., Yin B., Willis N.A., Bronson R.T., Crowley D., Jacks T.: Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome. Cell 119: 847-60, 2004.
  • 6
    • 0033747336 scopus 로고    scopus 로고
    • A gain of function p53 mutant promotes both genomic instability and cell survival in a novel p53-null mammary epithelial cell model
    • Murphy K.L., Dennis A.P., Rosen J.M.: A gain of function p53 mutant promotes both genomic instability and cell survival in a novel p53-null mammary epithelial cell model. Faseb. J. 14: 2291-2302, 2000.
    • (2000) Faseb. J , vol.14 , pp. 2291-2302
    • Murphy, K.L.1    Dennis, A.P.2    Rosen, J.M.3
  • 7
    • 0035421961 scopus 로고    scopus 로고
    • Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis
    • Matas D., Sigal A., Stambolsky P., Milyavsky M., Weisz L., Schwartz D., Goldfinger N., Rotter V.: Integrity of the N-terminal transcription domain of p53 is required for mutant p53 interference with drug-induced apoptosis. Embo J. 20: 4163-4172, 2001.
    • (2001) Embo J , vol.20 , pp. 4163-4172
    • Matas, D.1    Sigal, A.2    Stambolsky, P.3    Milyavsky, M.4    Weisz, L.5    Schwartz, D.6    Goldfinger, N.7    Rotter, V.8
  • 8
    • 0034910622 scopus 로고    scopus 로고
    • Molecular genetics of small cell lung carcinoma
    • Wistuba I.I., Gazdar A.F., Minna J.D.: Molecular genetics of small cell lung carcinoma. Semin. Oncol. 28: 3-13, 2001.
    • (2001) Semin. Oncol , vol.28 , pp. 3-13
    • Wistuba, I.I.1    Gazdar, A.F.2    Minna, J.D.3
  • 9
    • 0026572475 scopus 로고
    • Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor beta 1
    • Gerwin B.I., Spillare E., Forrester K., Lehman T.A., Kispert J., Welsh J.A., et al.: Mutant p53 can induce tumorigenic conversion of human bronchial epithelial cells and reduce their responsiveness to a negative growth factor, transforming growth factor beta 1. Proc. Natl. Acad. Sci. U.S.A. 89(7): 2759-2763, 1992.
    • (1992) Proc. Natl. Acad. Sci. U.S.A , vol.89 , Issue.7 , pp. 2759-2763
    • Gerwin, B.I.1    Spillare, E.2    Forrester, K.3    Lehman, T.A.4    Kispert, J.5    Welsh, J.A.6
  • 10
    • 14444269227 scopus 로고    scopus 로고
    • Effects of p53 mutants derived from lung carcinomas on the p53-responsive element (p53KE) of the MDM2 gene
    • Gorgoulis V.G., Zacharatos P.V., Manolis E., Ikonomopoulos J.A., Damalas A., Lamprinopoulos C., et al.: Effects of p53 mutants derived from lung carcinomas on the p53-responsive element (p53KE) of the MDM2 gene. Br. J. Cancer 77(3): 374-384, 1998.
    • (1998) Br. J. Cancer , vol.77 , Issue.3 , pp. 374-384
    • Gorgoulis, V.G.1    Zacharatos, P.V.2    Manolis, E.3    Ikonomopoulos, J.A.4    Damalas, A.5    Lamprinopoulos, C.6
  • 11
    • 0033552948 scopus 로고    scopus 로고
    • Mutant p53 gain of function: Differential effects of different p53 mutants on resistance of cultured cells to chemotherapy
    • Blandino G., Levine A.J., and Oren M.: Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy. Oncogene 18(2): 477-485, 1999.
    • (1999) Oncogene , vol.18 , Issue.2 , pp. 477-485
    • Blandino, G.1    Levine, A.J.2    Oren, M.3
  • 16
    • 0034671945 scopus 로고    scopus 로고
    • Oncogenic mutations of the p53 tumor suppressor: The demons of the guardian of the genome
    • Sigal A., Rotter V.: Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome. Cancer Res. 60: 6788-6793, 2000.
    • (2000) Cancer Res , vol.60 , pp. 6788-6793
    • Sigal, A.1    Rotter, V.2
  • 17
    • 0042337367 scopus 로고    scopus 로고
    • Zalcenstein A., Stambolsky P., Weisz L., Muller M., Wallach D., Goncharov T.M., Krammer P.H., Rotter V., Oren M.: Mutant p53 gain of function: repression of CD95 (Fas/APO-1) gene expression by tumor-associated p53 mutants. Oncogene 22: 5667-5676, 2003.
    • Zalcenstein A., Stambolsky P., Weisz L., Muller M., Wallach D., Goncharov T.M., Krammer P.H., Rotter V., Oren M.: Mutant p53 gain of function: repression of CD95 (Fas/APO-1) gene expression by tumor-associated p53 mutants. Oncogene 22: 5667-5676, 2003.
  • 18
    • 0035179779 scopus 로고    scopus 로고
    • Tumor suppressor genes: At the crossroads of molecular carcinogenesis, molecular epidemiology and human risk assessment
    • Hussain S.P., Hofseth L.J., Harris C.C.: Tumor suppressor genes: at the crossroads of molecular carcinogenesis, molecular epidemiology and human risk assessment. Lung Cancer 34 Suppl 2: 87-15, 2001.
    • (2001) Lung Cancer , vol.34 , Issue.SUPPL. 2 , pp. 87-15
    • Hussain, S.P.1    Hofseth, L.J.2    Harris, C.C.3
  • 20
    • 0033601370 scopus 로고    scopus 로고
    • Pharmacological rescue of mutant p53 conformation and function
    • Foster B.A., Coffey H.A., Morin M.J., Rastinejad F.: Pharmacological rescue of mutant p53 conformation and function. Science 286: 2507-2510, 1999.
    • (1999) Science , vol.286 , pp. 2507-2510
    • Foster, B.A.1    Coffey, H.A.2    Morin, M.J.3    Rastinejad, F.4
  • 21
    • 0036175271 scopus 로고    scopus 로고
    • Prognostic role of p27(Kip1) expression in oral squamous cell carcinoma in Taiwan
    • Kuo M.Y., Hsu H.Y., Kok S.H., Kuo R.C., Yang H., Hahn L.J., Chiang C.P.: Prognostic role of p27(Kip1) expression in oral squamous cell carcinoma in Taiwan. Oral. Oncol. 38: 172-178, 2002.
    • (2002) Oral. Oncol , vol.38 , pp. 172-178
    • Kuo, M.Y.1    Hsu, H.Y.2    Kok, S.H.3    Kuo, R.C.4    Yang, H.5    Hahn, L.J.6    Chiang, C.P.7
  • 23
    • 0038274163 scopus 로고    scopus 로고
    • Links between tumor suppressors: P53 is required for TGF-beta gene responses by cooperating with Smads
    • Cordenonsi M., Dupont S., Maretto S., Insinga A., Imbriano C., Piccolo S.: Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads. Cell 113: 301-314, 2003.
    • (2003) Cell , vol.113 , pp. 301-314
    • Cordenonsi, M.1    Dupont, S.2    Maretto, S.3    Insinga, A.4    Imbriano, C.5    Piccolo, S.6
  • 24
    • 0036467496 scopus 로고    scopus 로고
    • TGF-beta signaling: Positive and negative effects on tumorigenesis
    • Wakefield L.M., Roberts A.B.: TGF-beta signaling: positive and negative effects on tumorigenesis. Curr. Opin. Genet. Dev. 12: 22-29, 2002.
    • (2002) Curr. Opin. Genet. Dev , vol.12 , pp. 22-29
    • Wakefield, L.M.1    Roberts, A.B.2
  • 26
    • 0031018483 scopus 로고    scopus 로고
    • Activin and inhibin have antagonistic effects on ligand-dependent heteromerization of the type I and type II activin receptors and human erythroid differentiation
    • Lebrun J.J., Vale W.W.: Activin and inhibin have antagonistic effects on ligand-dependent heteromerization of the type I and type II activin receptors and human erythroid differentiation. Mol. Cell. Biol. 17: 1682-1691, 1997.
    • (1997) Mol. Cell. Biol , vol.17 , pp. 1682-1691
    • Lebrun, J.J.1    Vale, W.W.2
  • 28
    • 2542471338 scopus 로고    scopus 로고
    • Interrelationship of growth differentiation factor 9 and inhibin in early folliculogenesis and ovarian tumorigenesis in mice
    • Wu X., Chen L., Brown C.A., Yan C., Matzuk M.M.: Interrelationship of growth differentiation factor 9 and inhibin in early folliculogenesis and ovarian tumorigenesis in mice. Mol. Endocrinol. 18: 1509-1519, 2004.
    • (2004) Mol. Endocrinol , vol.18 , pp. 1509-1519
    • Wu, X.1    Chen, L.2    Brown, C.A.3    Yan, C.4    Matzuk, M.M.5
  • 30
    • 0029757120 scopus 로고    scopus 로고
    • Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor 1 receptor gene
    • Werner H., Karnieli E., Rauscher F.J., LeRoith D.: Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor 1 receptor gene. Proc. Natl. Acad. Sci. USA 93: 8318-8323, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 8318-8323
    • Werner, H.1    Karnieli, E.2    Rauscher, F.J.3    LeRoith, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.