Low and moderate remifentanil infusion rates do not alter target-controlled infusion propofol concentrations necessary to maintain anesthesia as assessed by bispectral index monitoring

Anesthesia and Analgesia

Volumn 104, Issue 2, 2007, Pages 325-331

  Wang, Lars P ^a   McLoughlin, Peter ^a   Paech, Michael J ^b   Kurowski, Irina ^a   Brandon, Emma L ^a  

^a ROYAL PERTH HOSPITAL   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

PROPOFOL; REMIFENTANIL;

ANESTHESIA; ARTICLE; BISPECTRAL INDEX; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG INFUSION; ENDOTRACHEAL INTUBATION; HUMAN; MAJOR CLINICAL STUDY; PATIENT MONITORING; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADULT; AGED; ANESTHESIA, INTRAVENOUS; ANESTHETICS, COMBINED; BLOOD PRESSURE; DRUG DELIVERY SYSTEMS; ELECTROENCEPHALOGRAPHY; HUMANS; INFUSIONS, INTRAVENOUS; MIDDLE AGED; MONITORING, PHYSIOLOGIC; PIPERIDINES; PROPOFOL;

EID: 33846441644     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/01.ane.0000252966.03103.89     Document Type: Article

References (26)

1. Kreuer S, Bruhn J, Larsen R, et al. Comparison of Alaris AEP and bispectral index during propofol-remifentanil anaesthesia. Br J Anaesth 2003;91:336-40.
2. 50 of propofol for laryngeal mask insertion. Br J Anaesth 2004;92:238-41.
3. Hoymork SC, Raeder J, Grimsmo B, Steen PA. Bispectral index, serum drug concentrations and emergence associated with individually adjusted target controlled infusions of remifentanil and propofol for laparoscopic surgery. Br J Anaesth 2003;91:773-80.
4. Leone M, Rousseau S, Avidan M, et al. Target concentrations of remifentanil with propofol to blunt coughing during intubation, cuff inflation and tracheal suctioning. Br J Anaesth 2004;93:660-3.
5. Drover DR, Litalien C, Wellis V, et al. Determination of the pharmacodynamic interaction of propofol and remifentanil during esophagogastroduodenoscopy in children. Anesthesiology 2004;100:1382-6.
6. Myles PS, Leslie KL, McNeil J, et al. B-aware Trial Group. Bispectral index monitoring to prevent awareness during anaesthesia: the B-aware randomised controlled trial. Lancet 2004;363:1757-63.
7. Wang LP, Hermann C, Westrin P. Thiopentone requirements in adults after varying pre-induction doses of fentanyl. Anaesthesia 1996;51:831-5.
8. Stockham RJ, Stanley TH, Pace NL, et al. Fentanyl pre-treatment modifies anaesthetic induction with etomidate. Anaesth Intensive Care 1988;16:171-5.
9. Kazama T, Ikeda K, Morita K. Reduction by fentanyl of the Cp sub 50 values of propofol and hemodynamic responses to various stimuli. Anesthesiology 1997;87:213-27.
10. Camu F, Royston D. Inpatient experience with remifentanil. Anesth Analg 1999;89:S15-S21.
11. Peacock JE, Philip BK. Ambulatory anesthesia experience with remifentanil. Anesth Analg 1999;89:S22-S27.
12. Koitabashi T, Johansen JW, Sebel PS. Remifentanil dose/ electroencephalogram bispectral response during combined propofol/regional anesthesia. Anesth Analg 2002;94:1530-3.
13. Strachan AN, Edwards ND. Randomized placebo controlled trial to assess the effect of remifentanil and propofol on bispectral index and sedation. Br J Anaesth 2000;84:489-90.
14. Dixon WJ. Quantal-response variable experimentation: the up-and-down method. In: McArthur JW, Colton T, eds. Statistics in endocrinology. Cambridge, MA: MIT Press, 1970;251-67.
15. Dixon WJ. Staircase bioassay: the up-and-down method. Neurosci Biobehav Rev 1991;15:47-50.
16. Forestier F, Hirschi M, Rouget P, et al. Propofol and sufentanil titration with the bispectral index to provide anesthesia for coronary artery surgery. Anesthesiology 2003;99:334-6.
17. Lysakowski C, Dumont L, Pellegrini M, et al. Effects of fentanyl, alfentanil, remifentanil and sufentanil on loss of consciousness and bispectral index during propofol induction of anaesthesia. Br J Anaesth 2001;86:523-7.
18. Bouillon TW, Bruhn J, Radulescu L, et al. Pharmacodynamic interaction between propofol and remifentanil regarding hypnosis, tolerance of laryngoscopy, bispectral index, and electroencephalographic approximate entropy. Anesthesiology 2004;100:1353-72.
19. Struys MMRF, Verecke H, Moerman A, et al. Ability of bispectral index autoregressive modeling with exogenous input-derived auditory evoked potentials, and predicted propofol concentrations to measure patient responsiveness during anesthesia with propofol and remifentanil. Anesthesiology 2003;99:802-12.
20. Kern SE, Guoming X, White JL, Egan TD. Opioid-hypnotic synergy. Anesthesiology 2004;100:1373-81.
21. Glen JB. Development of 'Diprifusior': a TCI system for propofol. Anaesthesia 1998;53:S13-S21.
22. Nunes CS, Ferreira DA, Antunes L, Amorim P. Clinical variables related to propofol effect-site concentrations at recovery of consciousness after neurosurgical procedures. J Neurosurg Anesthesiol 2005;17:110-14.
23. Egan TD, Minto CF, Hermann DJ, et al. Remifentanil versus alfentanil. Comparative pharmacokinetics and pharmacodynamics in healthy adult male volunteers. Anesthesiology 1996;84:821-33.
24. Ludbrook GL, Upton RN. Pharmacokinetic drug interaction between propofol and remifentanil? [letter]. Anesth Analg 2003;97:924-5.
25. Bouillon T, Bruhn J, Radu-Radulesco L, et al. Non-steady state analysis of the pharmacokinetic interaction between propofol and remifentanil. Anesthesiology 2002;97:1350-62.
26. De Baerdemaeker LEC, Mortier EP, Struys MMRF. Pharmacokinetics in obese patients. Contin Edu Anaesth Crit Care Pain 2004;4:152-5.