Pharmacokinetics in obese patients

Continuing Education in Anaesthesia, Critical Care and Pain

Volumn 4, Issue 5, 2004, Pages 152-155

  De Baerdemaeker, Luc E C ^a   Mortier, Eric P ^a   Struys, Michel M R F ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33644573439     PISSN: 17431816     EISSN: 17431824     Source Type: Journal    
DOI: 10.1093/bjaceaccp/mkh042     Document Type: Article

References (10)

1. Blouin RA, Kolpek JH, Mann HJ. Influence of obesity on drug disposition. Clin Pharm 1987; 6: 706-14.
2. Bouillon T, Shafer SL. Does size matter?. Anesthesiology 1998; 89: 557-60.
3. Buckley FP. Anaesthesia for the morbidly obese patient. Can J Anaesth 1994; 41: R94-R100.
4. Gepts E, Shafer SL, Camu F, et al. Linearity of pharmacokinetics and model estimation of sufentanil. Anesthesiology 1995; 83: 1194-204.
5. Gepts E. Pharmacokinetic concepts for TCI anaesthesia. Anaesthesia 1998; 53 (Suppl. 1): 4-12
6. Marsh B, White M, Morton N, Kenny GN. Pharmacokinetic model driven infusion of propofol in children. Br J Anaesth 1991; 67: 41-8.
7. Oberg B, Poulsen TD. Obesity: an anaesthetic challenge. Acta Anaesthesiol Scand 1996; 40: 191-200.
8. Schnider TW, Minto CF, Gambus PL, et al. The influence of method of administration and covariates on the pharmacokinetics of propofol in adult volunteers. Anesthesiology 1998; 88: 1170-82.
9. Schuttler J, Ihmsen H. Population pharmacokinetics of propofol: a multicenter study. Anesthesiology 2000; 92: 727-38.
10. Wada DR, Bjorkman S, Ebling WF, Harashima H, Harapat SR, Stanski DR. Computer simulation of the effects of alterations in blood flows and body composition on thiopental pharmacokinetics in humans. Anesthesiology 1997; 87: 884-99.