메뉴 건너뛰기




Volumn 37, Issue 2, 2007, Pages 251-260

Hypoallergenic mutants of Ole e 1, the major olive pollen allergen, as candidates for allergy vaccines

Author keywords

Allergy; Hypoallergen; Mouse model; Ole e 1; Olive pollen allergen

Indexed keywords

BETA N ACETYLHEXOSAMINIDASE; COMPLEMENTARY DNA; CYTOKINE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1 ANTIBODY; OLE E 1 ANTIGEN; POLLEN ANTIGEN; UNCLASSIFIED DRUG; VACCINE;

EID: 33846439330     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2006.02632.x     Document Type: Article
Times cited : (26)

References (50)
  • 1
    • 0035495857 scopus 로고    scopus 로고
    • The germless theory of allergic disease: Revisiting the hygiene hypothesis
    • Wills-Karp M, Santeliz J, Karp CL. The germless theory of allergic disease: revisiting the hygiene hypothesis. Nat Rev Immunol 2001; 1:69-75.
    • (2001) Nat Rev Immunol , vol.1 , pp. 69-75
    • Wills-Karp, M.1    Santeliz, J.2    Karp, C.L.3
  • 3
    • 1042298988 scopus 로고    scopus 로고
    • Strategies for converting allergens into hypoallergenic vaccine candidates
    • Vrtala S, Focke-Tejkl M, Swoboda I, Kraft D, Valenta R. Strategies for converting allergens into hypoallergenic vaccine candidates. Methods 2004; 32:313-20.
    • (2004) Methods , vol.32 , pp. 313-320
    • Vrtala, S.1    Focke-Tejkl, M.2    Swoboda, I.3    Kraft, D.4    Valenta, R.5
  • 6
    • 0035958872 scopus 로고    scopus 로고
    • Ole e 9, a major olive pollen allergen is a 1,3-beta-glucanase. Isolation, characterization, amino acid sequence, and tissue specificity
    • Huecas S, Villalba M, Rodríguez R. Ole e 9, a major olive pollen allergen is a 1,3-beta-glucanase. Isolation, characterization, amino acid sequence, and tissue specificity. J Biol Chem 2001; 276:27959-66.
    • (2001) J Biol Chem , vol.276 , pp. 27959-27966
    • Huecas, S.1    Villalba, M.2    Rodríguez, R.3
  • 7
    • 1542724437 scopus 로고    scopus 로고
    • A major allergen from pollen defines a novel family of plant proteins and shows intra- and interspecies cross-reactivity
    • Barral P, Batanero E, Palomares O, Quiralte J, Villalba M, Rodríguez R. A major allergen from pollen defines a novel family of plant proteins and shows intra- and interspecies cross-reactivity. J Immunol 2004; 172:3644-51.
    • (2004) J Immunol , vol.172 , pp. 3644-3651
    • Barral, P.1    Batanero, E.2    Palomares, O.3    Quiralte, J.4    Villalba, M.5    Rodríguez, R.6
  • 8
    • 0023942452 scopus 로고
    • Olive (Olea europaea). I. Immunochemical characterization by immunoblotting, CRIE and immunodetection by a monoclonal antibody
    • Lauzurica P, Gurbindo C, Maruri N et al. Olive (Olea europaea). I. Immunochemical characterization by immunoblotting, CRIE and immunodetection by a monoclonal antibody. Mol Immunol 1988; 25:329-35.
    • (1988) Mol Immunol , vol.25 , pp. 329-335
    • Lauzurica, P.1    Gurbindo, C.2    Maruri, N.3
  • 9
    • 0025179664 scopus 로고
    • Heterogeneity of a major allergen from olive (Olea europea) pollen
    • Wheeler AW, Hickman BE, Fox B. Heterogeneity of a major allergen from olive (Olea europea) pollen. Mol Immunol 1990; 27:631-6.
    • (1990) Mol Immunol , vol.27 , pp. 631-636
    • Wheeler, A.W.1    Hickman, B.E.2    Fox, B.3
  • 10
    • 0029047612 scopus 로고
    • Lol p XI, a new major grass pollen allergen, is a member of family of soybean trypsin inhibitor-related proteins
    • Van Ree R, Hoffman DR, van Dijk W et al. Lol p XI, a new major grass pollen allergen, is a member of family of soybean trypsin inhibitor-related proteins. J Allergy Clin Immunol 1995; 95:970-8.
    • (1995) J Allergy Clin Immunol , vol.95 , pp. 970-978
    • Van Ree, R.1    Hoffman, D.R.2    van Dijk, W.3
  • 11
    • 0035083451 scopus 로고    scopus 로고
    • Purification and characterization of the main allergen of Plantago lanceolata pollen, Pla l 1
    • Calabozo B, Barber D, Polo F. Purification and characterization of the main allergen of Plantago lanceolata pollen, Pla l 1. Clin Exp Allergy 2001; 31:322-30.
    • (2001) Clin Exp Allergy , vol.31 , pp. 322-330
    • Calabozo, B.1    Barber, D.2    Polo, F.3
  • 12
    • 0036119951 scopus 로고    scopus 로고
    • Identification and characterization of Che a 1 allergen from Chenopodium album pollen
    • Barderas R, Villalba M, Lombardero M, Rodríguez R. Identification and characterization of Che a 1 allergen from Chenopodium album pollen. Int Arch Allergy Immunol 2002; 127:47-54.
    • (2002) Int Arch Allergy Immunol , vol.127 , pp. 47-54
    • Barderas, R.1    Villalba, M.2    Lombardero, M.3    Rodríguez, R.4
  • 14
    • 0030468007 scopus 로고    scopus 로고
    • Batanero E, González de la Peña MA, Villalba M, Monsalve RI, Martín-Estaban M, Rodríguez R. Isolation, cDNA cloning and expression of Lig v 1, the major allergen from privet pollen. Clin Exp Allergy 1996; 26:1401-10.
    • Batanero E, González de la Peña MA, Villalba M, Monsalve RI, Martín-Estaban M, Rodríguez R. Isolation, cDNA cloning and expression of Lig v 1, the major allergen from privet pollen. Clin Exp Allergy 1996; 26:1401-10.
  • 15
    • 0028201767 scopus 로고
    • Isolation and characterization of an olive allergen-like protein from lilac pollen. Sequence analysis of three cDNA encoding protein isoforms
    • Batanero E, Villalba M, López-Otín C, Rodríguez R. Isolation and characterization of an olive allergen-like protein from lilac pollen. Sequence analysis of three cDNA encoding protein isoforms. Eur J Biochem 1994; 221:187-93.
    • (1994) Eur J Biochem , vol.221 , pp. 187-193
    • Batanero, E.1    Villalba, M.2    López-Otín, C.3    Rodríguez, R.4
  • 16
    • 0027435006 scopus 로고
    • The amino acid sequence of Ole e I, the major allergen from olive tree (Olea europaea) pollen
    • Villalba M, Batanero E, López-Otín C et al. The amino acid sequence of Ole e I, the major allergen from olive tree (Olea europaea) pollen. Eur J Biochem 1993; 216:863-9.
    • (1993) Eur J Biochem , vol.216 , pp. 863-869
    • Villalba, M.1    Batanero, E.2    López-Otín, C.3
  • 17
    • 0028175841 scopus 로고
    • Cloning and expression of Ole e I, the major allergen from olive tree pollen: Polymorphism analysis and tissue specificity
    • Villalba M, Batanero E, Monsalve RI, González de la Peña MA, Lahoz C, Rodríguez R. Cloning and expression of Ole e I, the major allergen from olive tree pollen: polymorphism analysis and tissue specificity. J Biol Chem 1994; 269:15217-22.
    • (1994) J Biol Chem , vol.269 , pp. 15217-15222
    • Villalba, M.1    Batanero, E.2    Monsalve, R.I.3    González de la Peña, M.A.4    Lahoz, C.5    Rodríguez, R.6
  • 18
    • 0033561258 scopus 로고    scopus 로고
    • Production and detailed characterization of biologically active olive pollen allergen Ole e 1 secreted by the yeast Pichia pastoris
    • Huecas S, Villalba M, Gónzalez E, Martínez-Ruiz A, Rodríguez R. Production and detailed characterization of biologically active olive pollen allergen Ole e 1 secreted by the yeast Pichia pastoris. Eur J Biochem 1999; 261:539-45.
    • (1999) Eur J Biochem , vol.261 , pp. 539-545
    • Huecas, S.1    Villalba, M.2    Gónzalez, E.3    Martínez-Ruiz, A.4    Rodríguez, R.5
  • 19
    • 0343628924 scopus 로고    scopus 로고
    • Immunological activity of recombinant Ole e 1 in patients with Olea europaea pollinosis
    • Quiralte J, González E, Arias de Saavedra JM et al. Immunological activity of recombinant Ole e 1 in patients with Olea europaea pollinosis. Int Arch Allergy Immunol 2000; 122:101-7.
    • (2000) Int Arch Allergy Immunol , vol.122 , pp. 101-107
    • Quiralte, J.1    González, E.2    Arias de Saavedra, J.M.3
  • 20
    • 14444272055 scopus 로고    scopus 로고
    • Olive pollen allergy: Searching for immunodominant T-cell epitopes on the Ole e 1 molecule
    • Cárdaba B, Del Pozo V, Jurado A et al. Olive pollen allergy: searching for immunodominant T-cell epitopes on the Ole e 1 molecule. Clin Exp Allergy 1998; 28:413-22.
    • (1998) Clin Exp Allergy , vol.28 , pp. 413-422
    • Cárdaba, B.1    Del Pozo, V.2    Jurado, A.3
  • 21
    • 0037105251 scopus 로고    scopus 로고
    • Influence of the 3D-conformation, glycan component and microheterogeneity on the epitope structure of Ole e 1, the major olive allergen. Use of recombinant isoforms and specific monoclonal antibodies as immunological tools
    • González E, Villalba M, Lombardero M, Aalbers M, van Ree R, Rodríguez R. Influence of the 3D-conformation, glycan component and microheterogeneity on the epitope structure of Ole e 1, the major olive allergen. Use of recombinant isoforms and specific monoclonal antibodies as immunological tools. Mol Immunol 2002; 39:93-101.
    • (2002) Mol Immunol , vol.39 , pp. 93-101
    • González, E.1    Villalba, M.2    Lombardero, M.3    Aalbers, M.4    van Ree, R.5    Rodríguez, R.6
  • 22
    • 28944431810 scopus 로고    scopus 로고
    • Analysis of IgE and IgG B-cell immunodominant regions of Ole e 1, the main allergen from olive pollen
    • González E, Villalba M, Quiralte J et al. Analysis of IgE and IgG B-cell immunodominant regions of Ole e 1, the main allergen from olive pollen. Mol Immunol 2006; 43:570-8.
    • (2006) Mol Immunol , vol.43 , pp. 570-578
    • González, E.1    Villalba, M.2    Quiralte, J.3
  • 23
    • 0030937231 scopus 로고    scopus 로고
    • Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T-cell epitope-containing fragments
    • Vrtala S, Hirtenleher K, Vangelista L et al. Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T-cell epitope-containing fragments. J Clin Invest 1997; 99:1673-81.
    • (1997) J Clin Invest , vol.99 , pp. 1673-1681
    • Vrtala, S.1    Hirtenleher, K.2    Vangelista, L.3
  • 24
    • 0031952580 scopus 로고    scopus 로고
    • Modulation of IgE reactivity of allergens by site-directed mutagenesis: Potential use of hypoallergenic variants for immunotherapy
    • Ferreira F, Ebner C, Kramer B et al. Modulation of IgE reactivity of allergens by site-directed mutagenesis: potential use of hypoallergenic variants for immunotherapy. FASEB J 1998; 12:231-42.
    • (1998) FASEB J , vol.12 , pp. 231-242
    • Ferreira, F.1    Ebner, C.2    Kramer, B.3
  • 25
    • 6344222889 scopus 로고    scopus 로고
    • Allergy vaccine engineering: Epitope modulation of recombinant Bet v 1 reduces IgE-binding but retains protein folding pattern for induction of protective blocking-antibody responses
    • Holm J, Gajhede M, Ferreras M et al. Allergy vaccine engineering: epitope modulation of recombinant Bet v 1 reduces IgE-binding but retains protein folding pattern for induction of protective blocking-antibody responses. J Immunol 2004; 173:5258-67.
    • (2004) J Immunol , vol.173 , pp. 5258-5267
    • Holm, J.1    Gajhede, M.2    Ferreras, M.3
  • 26
    • 0030854098 scopus 로고    scopus 로고
    • Engineering of the major house dust mite allergen Der f 2 for allergen-specific immunotherapy
    • Takai T, Yokota T, Yasue N et al. Engineering of the major house dust mite allergen Der f 2 for allergen-specific immunotherapy. Nature Biotechnology 1997; 15:754-8.
    • (1997) Nature Biotechnology , vol.15 , pp. 754-758
    • Takai, T.1    Yokota, T.2    Yasue, N.3
  • 27
    • 6344225313 scopus 로고    scopus 로고
    • Hypoallergenic variants of the major latex allergen Hev b 6.01 retaining human T lymphocyte reactivity
    • Drew AC, Eusebius NP, Kenins L et al. Hypoallergenic variants of the major latex allergen Hev b 6.01 retaining human T lymphocyte reactivity. J Immunol 2004; 173:5872-89.
    • (2004) J Immunol , vol.173 , pp. 5872-5889
    • Drew, A.C.1    Eusebius, N.P.2    Kenins, L.3
  • 28
    • 0036149973 scopus 로고    scopus 로고
    • Mutants of the major ryegrass pollen allergen, Lol p 5, with reduced IgE-binding capacity: Candidates for grass pollen-specific immunotherapy
    • Swoboda I, de Weerd N, Bhalla PL et al. Mutants of the major ryegrass pollen allergen, Lol p 5, with reduced IgE-binding capacity: candidates for grass pollen-specific immunotherapy. Eur J Biochem 2002; 32:295-302.
    • (2002) Eur J Biochem , vol.32 , pp. 295-302
    • Swoboda, I.1    de Weerd, N.2    Bhalla, P.L.3
  • 29
    • 1642344674 scopus 로고    scopus 로고
    • The recombinant major allergen of Parietaria judaica and its hypoallergenic variant: In vivo evaluation in a murine model of allergic sensitization
    • Orlandi A, Grasso F, Corinti S et al. The recombinant major allergen of Parietaria judaica and its hypoallergenic variant: in vivo evaluation in a murine model of allergic sensitization. Clin Exp Allergy 2004; 34:470-7.
    • (2004) Clin Exp Allergy , vol.34 , pp. 470-477
    • Orlandi, A.1    Grasso, F.2    Corinti, S.3
  • 30
    • 0033558133 scopus 로고    scopus 로고
    • Allergen engineering: Variants of the timothy grass pollen allergen Phl p 5b with reduced IgE-binding capacity but conserved T-cell reactivity
    • Schramm G, Kahlert H, Suck R et al. Allergen engineering: variants of the timothy grass pollen allergen Phl p 5b with reduced IgE-binding capacity but conserved T-cell reactivity. J Immunol 1999; 162:2406-14.
    • (1999) J Immunol , vol.162 , pp. 2406-2414
    • Schramm, G.1    Kahlert, H.2    Suck, R.3
  • 31
    • 11144358070 scopus 로고    scopus 로고
    • Generation of an allergy vaccine by disruption of the three-dimensional structure of the cross-reactive calcium-binding allergen, Phl p7
    • Westritschnig K, Focke M, Verdino P et al. Generation of an allergy vaccine by disruption of the three-dimensional structure of the cross-reactive calcium-binding allergen, Phl p7. J Immunol 2004; 172:5684-92.
    • (2004) J Immunol , vol.172 , pp. 5684-5692
    • Westritschnig, K.1    Focke, M.2    Verdino, P.3
  • 32
    • 0026563677 scopus 로고
    • Monoclonal antibodies against Olea europaea major allergen: Allergenic activity of affinity-purified allergen and depleted extract and development of a radioimmunoassay for the quantification of the allergen
    • Lombardero M, Quirce S, Duffort O et al. Monoclonal antibodies against Olea europaea major allergen: allergenic activity of affinity-purified allergen and depleted extract and development of a radioimmunoassay for the quantification of the allergen. J Allergy Clin Immunol 1992; 89:884-94.
    • (1992) J Allergy Clin Immunol , vol.89 , pp. 884-894
    • Lombardero, M.1    Quirce, S.2    Duffort, O.3
  • 33
    • 0033910097 scopus 로고    scopus 로고
    • A sensitive monoclonal antibody sandwich ELISA for the measurement of the major olive pollen allergen Ole e 1
    • Van Ree R, Aalbers M, Kea O et al. A sensitive monoclonal antibody sandwich ELISA for the measurement of the major olive pollen allergen Ole e 1. Int Arch Allergy Immunol 2000; 122:224-8.
    • (2000) Int Arch Allergy Immunol , vol.122 , pp. 224-228
    • Van Ree, R.1    Aalbers, M.2    Kea, O.3
  • 34
    • 0029862427 scopus 로고    scopus 로고
    • Ole e 3, an olive-tree allergen, belongs to a widespread family of pollen proteins
    • Batanero E, Villalba M, Ledesma A, Puente XS, Rodríguez R. Ole e 3, an olive-tree allergen, belongs to a widespread family of pollen proteins. Eur J Biochem 1996; 241:772-8.
    • (1996) Eur J Biochem , vol.241 , pp. 772-778
    • Batanero, E.1    Villalba, M.2    Ledesma, A.3    Puente, X.S.4    Rodríguez, R.5
  • 35
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmeli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227:680-5.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmeli, U.K.1
  • 37
    • 11444264766 scopus 로고    scopus 로고
    • Che a 1: Recombinant expression, purification and equivalence with the natural form
    • Barderas R, Villalba M, Rodríguez R. Che a 1: recombinant expression, purification and equivalence with the natural form. Int Arch Allergy Immunol 2004; 135:284-92.
    • (2004) Int Arch Allergy Immunol , vol.135 , pp. 284-292
    • Barderas, R.1    Villalba, M.2    Rodríguez, R.3
  • 38
    • 0036094231 scopus 로고    scopus 로고
    • Sensitization of mice with olive pollen allergen Ole e 1 induces a Th2 response
    • Batanero E, Barral P, Villalba M, Rodríguez R. Sensitization of mice with olive pollen allergen Ole e 1 induces a Th2 response. Int Arch Allergy Immunol 2002; 127:269-75.
    • (2002) Int Arch Allergy Immunol , vol.127 , pp. 269-275
    • Batanero, E.1    Barral, P.2    Villalba, M.3    Rodríguez, R.4
  • 39
    • 0009482260 scopus 로고
    • Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Procedure and some applications
    • Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Procedure and some applications. Proc Natl Acad Sci USA 1979; 76:4350-4.
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 4350-4354
    • Towbin, H.1    Staehelin, T.2    Gordon, J.3
  • 40
    • 0031048020 scopus 로고    scopus 로고
    • Biological allergen assay for in vivo test allergens with an in vitro model of the murine type I reactions
    • Hoffmann A, Vieths S, Haustin D. Biological allergen assay for in vivo test allergens with an in vitro model of the murine type I reactions. J Allergy Clin Immunol 1997; 99:227-32.
    • (1997) J Allergy Clin Immunol , vol.99 , pp. 227-232
    • Hoffmann, A.1    Vieths, S.2    Haustin, D.3
  • 41
    • 4544343180 scopus 로고    scopus 로고
    • Transition from botanical to a molecular classification in tree pollen allergy: Implications for diagnosis and therapy
    • Mothes N, Horak F, Valenta R. Transition from botanical to a molecular classification in tree pollen allergy: implications for diagnosis and therapy. Int Arch Allergy Immunol 2004; 135:357-73.
    • (2004) Int Arch Allergy Immunol , vol.135 , pp. 357-373
    • Mothes, N.1    Horak, F.2    Valenta, R.3
  • 42
    • 0002597936 scopus 로고
    • Which structural features determine protein antigenicity?
    • Van Regenmortel MHV. Which structural features determine protein antigenicity? Trends Biol Sci 1986; 11:36-9.
    • (1986) Trends Biol Sci , vol.11 , pp. 36-39
    • Van Regenmortel, M.H.V.1
  • 43
    • 0036284952 scopus 로고    scopus 로고
    • Modification of peanut allergen Ara h 3: Effects on IgE-binding and T-cell stimulation
    • Rabjohn P, West CM, Connaughton C et al. Modification of peanut allergen Ara h 3: effects on IgE-binding and T-cell stimulation. Int Arch Allergy Immunol 2002; 128:15-23.
    • (2002) Int Arch Allergy Immunol , vol.128 , pp. 15-23
    • Rabjohn, P.1    West, C.M.2    Connaughton, C.3
  • 44
    • 10744220314 scopus 로고    scopus 로고
    • Construction of hevein (Hev b 6.02) with reduced allergenicity for immunotherapy of latex by commutation of six acid residues on the conformational IgE epitopes
    • Karisola P, Mikkola J, Kalkkinen N et al. Construction of hevein (Hev b 6.02) with reduced allergenicity for immunotherapy of latex by commutation of six acid residues on the conformational IgE epitopes. J Immunol 2004; 172:2621-8.
    • (2004) J Immunol , vol.172 , pp. 2621-2628
    • Karisola, P.1    Mikkola, J.2    Kalkkinen, N.3
  • 45
    • 0034544450 scopus 로고    scopus 로고
    • T-cell epitope-containing hypoallergenic recombinant fragments of the major birch pollen allergen, Bet v 1, induce blocking antibodies
    • Vrtala S, Akdis CA, Budak F et al. T-cell epitope-containing hypoallergenic recombinant fragments of the major birch pollen allergen, Bet v 1, induce blocking antibodies. J Immunol 2000; 165:6653-9.
    • (2000) J Immunol , vol.165 , pp. 6653-6659
    • Vrtala, S.1    Akdis, C.A.2    Budak, F.3
  • 47
    • 0033197966 scopus 로고    scopus 로고
    • +T cells by inhibiting serum-IgE-facilitated allergen presentation
    • +T cells by inhibiting serum-IgE-facilitated allergen presentation. J Immunol 1999; 163:2944-52.
    • (1999) J Immunol , vol.163 , pp. 2944-2952
    • Van Neerven, R.J.1    Wikborh, T.2    Lund, G.3
  • 48
    • 0043258973 scopus 로고    scopus 로고
    • Inhibition of allergen-IgE-binding to B cells by IgG antibodies after grass pollen immunotherapy
    • Wachholz PA, Soni NK, Till SJ, Durham SR. Inhibition of allergen-IgE-binding to B cells by IgG antibodies after grass pollen immunotherapy. J Allergy Clin Immunol 2003; 112:915-22.
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 915-922
    • Wachholz, P.A.1    Soni, N.K.2    Till, S.J.3    Durham, S.R.4
  • 49
    • 0032783475 scopus 로고    scopus 로고
    • B cell epitopes of themajor timothy grass pollen allergen, Phl p 1, revealed by gene fragmentation as candidate for immunotherapy
    • Ball T, Fuchs T, Sperr WR et al. B cell epitopes of themajor timothy grass pollen allergen, Phl p 1, revealed by gene fragmentation as candidate for immunotherapy. FASEB J 1999; 13:1277-90.
    • (1999) FASEB J , vol.13 , pp. 1277-1290
    • Ball, T.1    Fuchs, T.2    Sperr, W.R.3
  • 50
    • 1042274839 scopus 로고    scopus 로고
    • Animal models of type I allergy using recombinant allergens
    • Herz U, Renz H, Wiedermann U. Animal models of type I allergy using recombinant allergens. Methods 2004; 32:271-80.
    • (2004) Methods , vol.32 , pp. 271-280
    • Herz, U.1    Renz, H.2    Wiedermann, U.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.