Loss of introns along the evolutionary diversification pathway of snake venom disintegrins evidenced by sequence analysis of genomic DNA from Macrovipera lebetina transmediterranea and Echis ocellatus

Journal of Molecular Evolution

Volumn 64, Issue 2, 2007, Pages 261-271

  Bazaa, Amine ^a   Juárez, Paula ^b   Marrakchi, Néziha ^a   Lasfer, Zakaria Bel ^a   Ayeb, Mohamed El ^a   Harrison, Robert A ^c   Calvete, Juan J ^b   Sanz, Libia ^b  

^a PASTEUR INSTITUTE OF TUNIS   (Tunisia)

^b INSTITUTO DE BIOMEDICINA DE VALENCIA   (Spain)

^c LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

Author keywords

Disintegrin evolution; Echis ocellatus; Genomic DNA; Intron sequence; Intronless gene; Macrovipera lebetina transmediterranea

Indexed keywords

COMPLEMENTARY DNA; DISINTEGRIN; GENOMIC DNA; HALYSTATIN 2; HALYSTATIN 3; PROTEIN DERIVATIVE; PROTEIN SUBUNIT; SNAKE VENOM; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; CONSENSUS; DNA DETERMINATION; DNA SEQUENCE; ECHIS OCELLATUS; EVOLUTION; GENETIC ANALYSIS; GENETIC ORGANIZATION; GENETIC TRANSCRIPTION; INTRON; MACROVIPERA LEBETINA TRANSMEDITERRANEA; MOLECULAR EVOLUTION; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN FAMILY; PROTEIN STRUCTURE; RNA SPLICING; SEQUENCE ANALYSIS; SNAKE; UNINDEXED SEQUENCE;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DISINTEGRINS; DNA; DNA PRIMERS; DNA, COMPLEMENTARY; INTRONS; MOLECULAR SEQUENCE DATA; PHYLOGENY; SEQUENCE ALIGNMENT; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID; VARIATION (GENETICS); VIPER VENOMS; VIPERIDAE;

ECHIS OCELLATUS; MACROVIPERA LEBETINA; VERTEBRATA; VIPERINAE;

EID: 33846434837     PISSN: 00222844     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00239-006-0161-4     Document Type: Article

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