Isomerization of 4-amino-6,7-diphenylbicyclo[2.2.2]octan-2-ones

Canadian Journal of Chemistry

Volumn 84, Issue 8, 2006, Pages 1074-1078

  Seebacher, Werner ^a   Saf, Robert ^a   Brun, Reto ^a   Kaiser, Marcel ^a   Weis, Robert ^a  

^a UNIVERSITY OF GRAZ   (Austria)

Author keywords

Aminobicyclo 2.2.2 octanones; Isomerization; Structure elucidation

Indexed keywords

BASIC CONDITIONS; REGIOSELECTIVELY;

ALKALINITY; ISOMERIZATION; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STEREOCHEMISTRY;

KETONES;

4 AMINO 6,7 DIPHENYLBICYCLO[2.2.2]OCTAN 2 ONE DERIVATIVE; CYCLOOCTANE DERIVATIVE; KETONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIPROTOZOAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; ISOMERIZATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE;

EID: 33846413033     PISSN: 00084042     EISSN: None     Source Type: Journal    
DOI: 10.1139/V06-135     Document Type: Article

References (11)

1. R. Weis, K. Schweiger, W. Seebacher, and F. Belaj. Tetrahedron, 54, 14015 (1998).
2. R. Weis, R. Brun, R. Saf, and W. Seebacher. Monatsh. Chem. 134, 1019 (2003).
3. W. Seebacher, R. Brun, and R. Weis. Eur. J. Pharm. Sci. 21, 225 (2004).
4. W. Seebacher, C. Schlapper, R. Brun, M. Kaiser, R. Saf, and R. Weis. Eur. J. Pharm. Sci. 24, 281 (2005).
5. W. Seebacher, R. Brun, M. Kaiser, R. Saf, and R. Weis. Eur. J. Med. Chem. 40, 888 (2005).
6. D.J. Muir and J.B. Stothers. Can. J. Chem. 71, 1099 (1993).
7. A. Nickon, J.L. Lambert, J.E. Oliver, D.F. Covey, and J. Morgan. J. Am. Chem. Soc. 98, 2593 (1976).
8. W. Seebacher, R. Brun, R. Saf, and R. Weis. Monatsh. Chem. 134, 1411 (2003).
9. H. Matile and J.R.L. Pink. In Immunological methods. Edited by I. Lefkovits and B. Pernis. Academic Press, San Diego. 1990. pp. 221-234.
10. T. Baltz, D. Baltz, C. Giroud, and J. Crockett. EMBO J. 4, 1273 (1985).
11. B. Räz, M. Iten, Y. Grether-Bühler, R. Kaminsky, and R. Brun. Acta Trop. 68, 139 (1997).