-
1
-
-
0029011218
-
The MAPK signaling cascade
-
Seger R., and Krebs E.G. The MAPK signaling cascade. FASEB J. 9 (1995) 726-735
-
(1995)
FASEB J.
, vol.9
, pp. 726-735
-
-
Seger, R.1
Krebs, E.G.2
-
2
-
-
0034997845
-
Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions
-
Pearson G., Robinson F., Gibson T.B., Xu B.E., Karandikar M., Berman K., et al. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr. Rev. 22 (2001) 153-183
-
(2001)
Endocr. Rev.
, vol.22
, pp. 153-183
-
-
Pearson, G.1
Robinson, F.2
Gibson, T.B.3
Xu, B.E.4
Karandikar, M.5
Berman, K.6
-
3
-
-
0035282334
-
Mammalian MAP kinase signaling cascades
-
Chang L., and Karin M. Mammalian MAP kinase signaling cascades. Nature 410 (2001) 37-40
-
(2001)
Nature
, vol.410
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
4
-
-
0030935258
-
Nuclear translocation of mitogen-activated protein kinase kinase (MEK1) in response to mitogenic stimulation
-
Jaaro H., Rubinfeld H., Hanoch T., and Seger R. Nuclear translocation of mitogen-activated protein kinase kinase (MEK1) in response to mitogenic stimulation. Proc. Natl. Acad. Sci. U. S. A. 94 (1997) 3742-3747
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 3742-3747
-
-
Jaaro, H.1
Rubinfeld, H.2
Hanoch, T.3
Seger, R.4
-
6
-
-
0033215340
-
Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimmer
-
Adachi M., Fukuda M., and Nishida E. Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimmer. EMBO J. 18 (1999) 5347-5358
-
(1999)
EMBO J.
, vol.18
, pp. 5347-5358
-
-
Adachi, M.1
Fukuda, M.2
Nishida, E.3
-
7
-
-
0032558692
-
Constitutive active ERK2 MAP kinase is sufficient for neurite outgrowth and cell transformation when targeted to the nucleus
-
Robinson M.J., Goldsmith E., White M.A., and Cobb M.H. Constitutive active ERK2 MAP kinase is sufficient for neurite outgrowth and cell transformation when targeted to the nucleus. Curr. Biol. 8 (1998) 1141-1150
-
(1998)
Curr. Biol.
, vol.8
, pp. 1141-1150
-
-
Robinson, M.J.1
Goldsmith, E.2
White, M.A.3
Cobb, M.H.4
-
8
-
-
1942521000
-
ERK1/2 is activated in non-small-cell lung cancer and associated with advanced tumours
-
Vicent S., Lopez-Picazo J.M., Toledo G., Lozano M.D., Torre W., Garcia-Corchon C., et al. ERK1/2 is activated in non-small-cell lung cancer and associated with advanced tumours. Br. J. Cancer 90 (2004) 1047-1052
-
(2004)
Br. J. Cancer
, vol.90
, pp. 1047-1052
-
-
Vicent, S.1
Lopez-Picazo, J.M.2
Toledo, G.3
Lozano, M.D.4
Torre, W.5
Garcia-Corchon, C.6
-
9
-
-
0032949934
-
Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin
-
Persons D.L., Yazlovitskaya E.M., Cui W., and Pelling J.C. Cisplatin-induced activation of mitogen-activated protein kinases in ovarian carcinoma cells: inhibition of extracellular signal-regulated kinase activity increases sensitivity to cisplatin. Clin. Cancer Res. 5 (1999) 1007-1014
-
(1999)
Clin. Cancer Res.
, vol.5
, pp. 1007-1014
-
-
Persons, D.L.1
Yazlovitskaya, E.M.2
Cui, W.3
Pelling, J.C.4
-
10
-
-
0033615657
-
Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplatin, sensitized human ovarian cancer cell line
-
Hayakawa J., Ohmichi M., Kurachi H., Ikegami H., Kimura A., Matsuoka T., et al. Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplatin, sensitized human ovarian cancer cell line. J. Biol. Chem. 274 (1999) 31648-31654
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 31648-31654
-
-
Hayakawa, J.1
Ohmichi, M.2
Kurachi, H.3
Ikegami, H.4
Kimura, A.5
Matsuoka, T.6
-
11
-
-
0034526814
-
Cisplatin-induced response of c-jun N-terminal kinase 1 and extracellular signal-regulated protein kinase 1 and 2 in a series of cisplatin-resistant ovarian carcinoma cell lines
-
Cui W., Yazlovitskaya E.M., Mayo M.S., Pelling J.C., and Persons D.L. Cisplatin-induced response of c-jun N-terminal kinase 1 and extracellular signal-regulated protein kinase 1 and 2 in a series of cisplatin-resistant ovarian carcinoma cell lines. Mol. Carcinog. 29 (2000) 219-228
-
(2000)
Mol. Carcinog.
, vol.29
, pp. 219-228
-
-
Cui, W.1
Yazlovitskaya, E.M.2
Mayo, M.S.3
Pelling, J.C.4
Persons, D.L.5
-
12
-
-
0035135510
-
The MEK1 inhibitor PD98059 sensitizes C8161 melanoma cells to cisplatin-induced apoptosis
-
Mandic A., Viktorsson K., Heiden T., Hansson J., and Shoshan M.C. The MEK1 inhibitor PD98059 sensitizes C8161 melanoma cells to cisplatin-induced apoptosis. Melanoma Res. 11 (2001) 11-19
-
(2001)
Melanoma Res.
, vol.11
, pp. 11-19
-
-
Mandic, A.1
Viktorsson, K.2
Heiden, T.3
Hansson, J.4
Shoshan, M.C.5
-
13
-
-
0034671751
-
Requirement for ERK activation in cisplatin-induced apoptosis
-
Wang X., Martindale X., and Holbrook J.L. Requirement for ERK activation in cisplatin-induced apoptosis. J. Biol. Chem. 275 (2000) 39435-39443
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 39435-39443
-
-
Wang, X.1
Martindale, X.2
Holbrook, J.L.3
-
14
-
-
0037091048
-
Increase of the resistance of human cervical carcinoma cells to cisplatin by inhibition of the MEK to ERK signaling pathway partly via enhancement of anticancer drug-induced NFκB activation
-
Yeh P.Y., Chuang S.E., Yeh K.H., Song Y.C., Ea C.K., and Cheng A.L. Increase of the resistance of human cervical carcinoma cells to cisplatin by inhibition of the MEK to ERK signaling pathway partly via enhancement of anticancer drug-induced NFκB activation. Biochem. Pharmacol. 63 (2002) 1423-1430
-
(2002)
Biochem. Pharmacol.
, vol.63
, pp. 1423-1430
-
-
Yeh, P.Y.1
Chuang, S.E.2
Yeh, K.H.3
Song, Y.C.4
Ea, C.K.5
Cheng, A.L.6
-
15
-
-
0036746965
-
Inhibition of aldose reductase enhances HeLa cell sensitivity to chemotherapeutic drugs and involves activation of extracellular signal-regulated kinases
-
Lee E.K., Regenold W.T., and Shapiro R. Inhibition of aldose reductase enhances HeLa cell sensitivity to chemotherapeutic drugs and involves activation of extracellular signal-regulated kinases. Anti-Cancer Drugs 13 (2002) 859-868
-
(2002)
Anti-Cancer Drugs
, vol.13
, pp. 859-868
-
-
Lee, E.K.1
Regenold, W.T.2
Shapiro, R.3
-
16
-
-
0036452342
-
Ras-mediated activation of ERK by cisplatin induces cell death independently of p53 in osteosarcoma and neuroblastoma cell lines
-
Woessmann W., Chen X., and Borkhardt A. Ras-mediated activation of ERK by cisplatin induces cell death independently of p53 in osteosarcoma and neuroblastoma cell lines. Cancer Chemother. Pharmacol. 50 (2002) 397-404
-
(2002)
Cancer Chemother. Pharmacol.
, vol.50
, pp. 397-404
-
-
Woessmann, W.1
Chen, X.2
Borkhardt, A.3
-
17
-
-
8544221913
-
Inhibition of extracellular-signal regulated kinases 1/2 is required for apoptosis of human colon cancer cells in vitro by sulindac metabolites
-
Rice P.L., Beard K.S., Driggers L.J., and Ahnen D.J. Inhibition of extracellular-signal regulated kinases 1/2 is required for apoptosis of human colon cancer cells in vitro by sulindac metabolites. Cancer Res. 64 (2004) 8148-8151
-
(2004)
Cancer Res.
, vol.64
, pp. 8148-8151
-
-
Rice, P.L.1
Beard, K.S.2
Driggers, L.J.3
Ahnen, D.J.4
-
18
-
-
4644261860
-
Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastin-induced apoptosis
-
Wu J., Wong W.W., Khosravi F., Minden M.D., and Penn L.Z. Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastin-induced apoptosis. Cancer Res. 64 (2004) 6461-6468
-
(2004)
Cancer Res.
, vol.64
, pp. 6461-6468
-
-
Wu, J.1
Wong, W.W.2
Khosravi, F.3
Minden, M.D.4
Penn, L.Z.5
-
19
-
-
3543020265
-
Subcellular localization determines the protective effects of activated ERK2 against distinct apoptogenic stimuli in myeloid leukemia cells
-
Ajenjo N., Canon E., Sanchez-Perez I., Matallanas D., Leon J., Perona R., and Crespo P. Subcellular localization determines the protective effects of activated ERK2 against distinct apoptogenic stimuli in myeloid leukemia cells. J. Biol. Chem. 279 (2004) 32813-32823
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 32813-32823
-
-
Ajenjo, N.1
Canon, E.2
Sanchez-Perez, I.3
Matallanas, D.4
Leon, J.5
Perona, R.6
Crespo, P.7
-
20
-
-
15544369937
-
Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line
-
Lee S., Choi E.J., Jin C., and Kim D.H. Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplification contributes to cisplatin resistance in an ovarian cancer cell line. Gynecol. Oncol. 97 (2005) 26-34
-
(2005)
Gynecol. Oncol.
, vol.97
, pp. 26-34
-
-
Lee, S.1
Choi, E.J.2
Jin, C.3
Kim, D.H.4
-
21
-
-
0035816678
-
Involvement of the activation loop of ERK in the detachment from cytosolic anchoring
-
Wolf I., Rubinfeld H., Yoon S., Marmor G., Hanoch T., and Seger R. Involvement of the activation loop of ERK in the detachment from cytosolic anchoring. J. Biol. Chem. 276 (2001) 24490-24497
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24490-24497
-
-
Wolf, I.1
Rubinfeld, H.2
Yoon, S.3
Marmor, G.4
Hanoch, T.5
Seger, R.6
-
22
-
-
4143052284
-
Cisplatin-induced cell death is EGFR/src/ERK signaling dependent in mouse proximal tubule cells
-
Arany I., Megyesi J.K., Kaneto H., Price P.M., and Safirstein R.L. Cisplatin-induced cell death is EGFR/src/ERK signaling dependent in mouse proximal tubule cells. Am. J. Physiol., Renal Fluid Electrolyte Physiol. 287 (2004) F543-F549
-
(2004)
Am. J. Physiol., Renal Fluid Electrolyte Physiol.
, vol.287
-
-
Arany, I.1
Megyesi, J.K.2
Kaneto, H.3
Price, P.M.4
Safirstein, R.L.5
-
23
-
-
0034680896
-
Effect of extracellular signal regulated kinase on p53 accumulation in response to cisplatin
-
Persons D.L., Yazlovitskaya E.M., and Pelling J.C. Effect of extracellular signal regulated kinase on p53 accumulation in response to cisplatin. J. Biol. Chem. 275 (2000) 35778-35785
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 35778-35785
-
-
Persons, D.L.1
Yazlovitskaya, E.M.2
Pelling, J.C.3
-
25
-
-
0036479137
-
Phorbol 12-myristate 13-acetate inhibits death receptor-mediated apoptosis in Jurkat cells by disrupting recruitment of Fas-associated polypeptide with death domain
-
Meng X.W., Heldebrant M.P., and Kaufmann S.H. Phorbol 12-myristate 13-acetate inhibits death receptor-mediated apoptosis in Jurkat cells by disrupting recruitment of Fas-associated polypeptide with death domain. J. Biol. Chem. 277 (2002) 3776-3783
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3776-3783
-
-
Meng, X.W.1
Heldebrant, M.P.2
Kaufmann, S.H.3
-
26
-
-
0036837872
-
Cytosolic retention of phosphorylated extracellular signal-regulated kinase and a Rho-associated kinase-mediated signal impair expression of p21Cip1/Waf1 in phorbol 12-myristate13-acetate-induced apoptotic cells
-
Lai J.M., Wu S., Huang D.Y., and Chang Z.F. Cytosolic retention of phosphorylated extracellular signal-regulated kinase and a Rho-associated kinase-mediated signal impair expression of p21Cip1/Waf1 in phorbol 12-myristate13-acetate-induced apoptotic cells. Mol. Cell. Biol. 22 (2002) 7581-7592
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7581-7592
-
-
Lai, J.M.1
Wu, S.2
Huang, D.Y.3
Chang, Z.F.4
-
27
-
-
1342308286
-
Phorbol 12-myristate 13-acetate protects Jurkat cells from Methylglyoxal-induced apoptosis by preventing c-Jun N-terminal kinase-mediated leakage of cytochrome c in an extracellular signal-regulated kinase-dependent manner
-
Takagi Y., Du J., Ma X.Y., Nakamura I., and Nagase F. Phorbol 12-myristate 13-acetate protects Jurkat cells from Methylglyoxal-induced apoptosis by preventing c-Jun N-terminal kinase-mediated leakage of cytochrome c in an extracellular signal-regulated kinase-dependent manner. Mol. Pharmacol. 65 (2004) 778-787
-
(2004)
Mol. Pharmacol.
, vol.65
, pp. 778-787
-
-
Takagi, Y.1
Du, J.2
Ma, X.Y.3
Nakamura, I.4
Nagase, F.5
-
28
-
-
0035504758
-
Differential activation of ERKs to focal adhesions by PKC epsilon is required for PMA-induced adhesion and migration of human glioma cells
-
Besson A., Davy A., Robbins S.M., and Yong V.W. Differential activation of ERKs to focal adhesions by PKC epsilon is required for PMA-induced adhesion and migration of human glioma cells. Oncogene 20 (2001) 7398-7407
-
(2001)
Oncogene
, vol.20
, pp. 7398-7407
-
-
Besson, A.1
Davy, A.2
Robbins, S.M.3
Yong, V.W.4
-
29
-
-
1542275216
-
Involvement of the ERK signaling cascade in protein kinase c-mediated cell cycle arrest in intestinal epithelial cells
-
Clark J.A., Black A.R., Leontieva O.V., Frey M.R., Pysz M.A., Kunneva L., et al. Involvement of the ERK signaling cascade in protein kinase c-mediated cell cycle arrest in intestinal epithelial cells. J. Biol. Chem. 279 (2004) 9233-9247
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 9233-9247
-
-
Clark, J.A.1
Black, A.R.2
Leontieva, O.V.3
Frey, M.R.4
Pysz, M.A.5
Kunneva, L.6
-
30
-
-
0031005028
-
Evidence for MEK-independent pathways regulating the prolonged activation of the ERK-MAP kinases
-
Grammer T.C., and Blenis J. Evidence for MEK-independent pathways regulating the prolonged activation of the ERK-MAP kinases. Oncogene 14 (1997) 1635-1642
-
(1997)
Oncogene
, vol.14
, pp. 1635-1642
-
-
Grammer, T.C.1
Blenis, J.2
-
31
-
-
0033590636
-
Constitutive activation of the 41/43 kDa mitogen-activated protein kinase signaling pathway in human tumors
-
Hoshino R., Chatani Y., Yamori T., Tsuruo T., Oka H., Yoshida O., et al. Constitutive activation of the 41/43 kDa mitogen-activated protein kinase signaling pathway in human tumors. Oncogene 18 (1999) 813-822
-
(1999)
Oncogene
, vol.18
, pp. 813-822
-
-
Hoshino, R.1
Chatani, Y.2
Yamori, T.3
Tsuruo, T.4
Oka, H.5
Yoshida, O.6
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