In vitro evaluation of the direct effect of estradiol on human osteoblasts (HOB) and human mesenchymal stem cells (h-MSCs)

Injury

Volumn 37, Issue 3 SUPPL., 2006, Pages

  DiSilvio, Lucy ^a   Jameson, Jacqueline ^a   Gamie, Zakareya ^b   Giannoudis, Peter V ^b   Tsiridis, Eleftherios ^a,b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

Bone; Estrogen; Formation; Osteoblasts; Proliferation; Receptor

Indexed keywords

ESTRADIOL; ESTROGEN; NITROBLUE TETRAZOLIUM; PROTEIN; TRYPAN BLUE;

ADULT; ARTICLE; CELL COUNT; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; CULTURE MEDIUM; HORMONE ACTION; HUMAN; HUMAN CELL; IMAGE ANALYSIS; MALE; MESENCHYMAL STEM CELL; NITROBLUE TETRAZOLIUM TEST; OSTEOBLAST; OSTEOPOROSIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; SCANNING ELECTRON MICROSCOPY;

ADULT; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; HUMANS; MALE; MESENCHYMAL STEM CELLS; OSTEOBLASTS; OSTEOPOROSIS;

EID: 33846392691     PISSN: 00201383     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.injury.2006.08.022     Document Type: Article

References (45)

1. Balasch J. Sex steroids and bone: current perspectives. Hum Reprod Update 9 3 (2003) 207-222
2. Bord S., Ireland D.C., Beaven S.R., et al. The effects of estrogen on osteoprotegerin, RANKL and estrogen receptor expression in human osteoblasts. Bone 32 2 (2003) 136-141
3. Bovenkerk S., Lanciloti N., and Chandar N. Induction of p53 expression and function by estrogen in osteoblasts. Calcif Tissue Int 73 3 (2003) 274-280
4. Cao L., Bu R., Oakley J.I., et al. Estrogen receptor-beta modulates synthesis of bone matrix proteins in human osteoblast-like MG63 cells. J Cell Biochem 89 1 (2003) 152-164
5. Chavassieux P., Serre C.M., Vergnaud P., et al. In vitro evaluation of dose-effects of ethanol on human osteoblastic cells. Bone Miner 22 2 (1993) 95-103
6. Chen F.P., Lee N., Wang K.C., et al. Effect of estrogen and 1alpha,25(OH)2-vitamin D3 on the activity and growth of human primary osteoblast-like cells in vitro. Fertil Steril 77 5 (2002) 1038-1043
7. Cheng M.Z., Rawlinson S.C., Pitsillides A.A., et al. Human osteoblasts' proliferative responses to strain and 17beta-estradiol are mediated by the estrogen receptor and the receptor for insulin-like growth factor I. J Bone Miner Res 17 4 (2002) 593-602
8. Cheung J., Mak Y.T., Papaioannou S., et al. Interleukin-6 (IL-6), IL-1, receptor activator of nuclear factor kappaB ligand (RANKL) and osteoprotegerin production by human osteoblastic cells: comparison of the effects of 17-beta oestradiol and raloxifene. J Endocrinol 177 3 (2003) 423-433
9. Christodoulou C., and Cooper C. What is osteoporosis?. Postgrad Med J 79 929 (2003) 133-138
10. Di Silvio L., and Gurav N. Osteoblasts. In: Koller M.R., Palsson B.O., and Masters J.R.W. (Eds). Human Cell Culture vol. 5 (2001), Kluwer Academic Publishers 221-241
11. Eghbali-Fatourechi G., Khosla S., Sanyal A., et al. Role of RANK ligand in mediating increased bone resorption in early postmenopausal women. J Clin Invest 111 8 (2003) 1221-1230
12. Eriksen E.F., Colvard D.S., Berg N.J., et al. Evidence of oestrogen receptors in normal human osteoblast-like cells. Science 241 4861 (1988) 82-86
13. Ernst M., Heath J.K., and Rodan G.A. Estradiol effects on proliferation, messenger ribonucleic acid for collagen and insulin-like growth factor-1, and parathyroid hormone-stimulated adenylate cyclase activity in osteoblastic cells from calvariae and long bones. Endocrinology 125 2 (1989) 825-833
14. Hofbauer L.C., Khosla S., Dunstan C.R., et al. Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells. Endocrinology 140 9 (1999) 4367-4370
15. Johnell O., and Kanis J. Epidemiology of osteoporotic fractures. Osteoporos Int 16 Suppl. 2 (2005) S3-S7
16. Kalu D.N., Liu C.C., Salerno E., et al. Skeletal response of ovariectomized rats to low and high doses of 17β-estradiol. Bone Miner 14 3 (1991) 175-187
17. Keeting P.E., Scott R.E., Colvard D.S., et al. Lack of a direct effect of estrogen on proliferation and differentiation of normal human osteoblast-like cells. J Bone Miner Res 6 3 (1991) 297-304
18. Komm B.S., Terpening C.M., Benz D.J., et al. Estrogen binding, receptor mRNA and biologic response in osteoblast-like osteosarcoma cells. Science 241 4861 (1988) 81-84
19. Kousteni S., Han L., Chen J., et al. Kinase-mediated regulation of common transcription factors accounts for the bone-protective effects of sex steroids. J Clin Invest 111 11 (2003) 1651-1664
20. Lee K., Jessop H., Suswillo R., et al. Endocrinology: bone adaptation requires oestrogen receptor-alpha. Nature 424 6947 (2003) 389
21. Luo X.H., and Liao E.Y. Effects of estriol on the proliferation and differentiation of human osteoblastic MG-63 cells. Endocr Res 29 3 (2003) 343-351
22. McCarthy T.L., Chang W.Z., Liu Y., et al. Runx2 integrates estrogen activity in osteoblasts. J Biol Chem 278 44 (2003) 43121-43129
23. Mochizuki S., Yoshida S., Yamanaka Y., et al. Effects of estriol on proliferative activity and expression of insulin-like growth factor-I (IGF-I) and IGF-I receptor mRNA in cultured human osteoblast-like osteosarcoma cells. Gynecol Endocrinol 20 1 (2005) 6-12
24. Monroe D.G., Getz B.J., Johnsen S.A., et al. Estrogen receptor isoform-specific regulation of endogenous gene expression in human osteoblastic cell lines expressing either ERalpha or ERbeta. J Cell Biochem 90 2 (2003) 315-326
25. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 65 1-2 (1983) 55-63
26. Nakayama G.R., Caton M.C., Nova M.P., et al. Assessment of the Alamar Blue assay for cellular growth and viability in vitro. J Immunol Methods 204 2 (1997) 205-208
27. Nguyen T.V., Centre J.R., and Eisman J.A. Osteoporosis: underrated, underdiagnosed and undertreated. Med J Aust 180 5 Suppl. (2004) S18-S22
28. Qu Q., Perala-Heape M., Kapanen A., et al. Estrogen enhances differentiation of osteoblasts in mouse bone marrow culture. Bone 22 3 (1998) 201-209
29. Okazaki R., Inoue D., Shibata M., et al. Estrogen promotes early osteoblast differentiation and inhibits adipocyte differentiation in mouse bone marrow stromal cell lines that express estrogen receptor (ER) alpha or beta. Endocrinology 143 6 (2002) 2349-2356
30. Raisz L.G. Pathogenesis of osteoporosis: concepts, conflicts, and prospects. J Clin Invest 115 12 (2005) 3318-3325
31. Reginster J.Y., and Burlet N. Osteoporosis: a still increasing prevalence. Bone 38 2 Suppl. 1 (2006) 4-9
32. Robinson J.A., Harris S.A., Riggs B.L., et al. Estrogen regulation of human osteoblastic cell proliferation and differentiation. Endocrinology 138 7 (1997) 2919-2927
33. Saika M., Inoue D., Kido S., et al. l7beta-estradiol stimulates expression of osteoprotegerin by a mouse stromal cell line, ST-2, via estrogen receptor-alpha. Endocrinology 142 6 (2001) 2205-2212
34. Sato K., Nohtomi K., Shizume K., et al. 17 Beta-estradiol increases calcium content in fetal mouse parietal bones cultured in serum-free medium only at physiological concentrations. Bone 19 3 (1996) 213-221
35. Scheven B.A., Damen C.A., Hamilton N.J., et al. Stimulatory effects of estrogen and progesterone on proliferation and differentiation of normal human osteoblast-like cells in vitro. Biochem Biophys Res Commun 186 1 (1992) 54-60
36. Seeman E., and Eisman J.A. Treatment of osteoporosis: why, whom, when and how to treat. The single most important consideration is the individual's absolute risk of fracture. Med J Aust 180 6 (2004) 298-303
37. Shamay A., Knopov V., and Benayahu D. The expression of estrogen receptor and estrogen effect in MBA-15 marrow stromal osteoblasts. Cell Biol Int 20 6 (1996) 401-405
38. Sims N.A., Morris H.A., Moore K.J., et al. Estradiol treatment transiently increases trabecular bone volume in ovariectomized rats. Bone 19 5 (1996) 455-461
39. Syed F., and Khosla S. Mechanisms of sex steroid effects on bone. Biochem Biophys Res Commun 328 3 (2005) 688-696
40. Turner R.T., Backup P., Sherman P.J., et al. Mechanism of action of estrogen on intramembranous bone formation: regulation of osteoblast differentiation and activity. Endocrinology 131 2 (1992) 883-889
41. Verhaar H.J.J., Damen C.A., Duursma S.A., et al. A comparison of the action of progestins and estrogen on the growth and differentiation of normal adult human osteoblast-like cells in vitro. Bone 15 3 (1994) 307-311
42. Waters K.M., Rickard D.J., Riggs B.L., et al. Estrogen regulation of human osteoblast function is determined by the stage of differentiation and the estrogen receptor isoform. J Cell Biochem 83 3 (2001) 448-462
43. Wiren K.M., Chapman Evans A., and Zhang X.W. Osteoblast differentiation influences androgen and estrogen receptor-alpha and -beta expression. J Endocrinol 175 3 (2002) 683-694
44. Zhou S., Zilberman Y., Wassermann K., et al. Estrogen modulates estrogen receptor alpha and beta expression, osteogenic activity, and apoptosis in mesenchymal stem cells (MSCs) of osteoporotic mice. J Cell Biochem 81 Suppl 36 (2001) 144-155
45. Zhou S., Turgeman G., Harris S.E., et al. Estrogens activate bone morphogenetic protein-2 gene transcription in mouse mesenchymal stem cells. Mol Endocrinol 17 1 (2003) 56-66