Effects of estriol on the proliferation and differentiation of human osteoblastic MG-63 cells

Endocrine Research

Volumn 29, Issue 3, 2003, Pages 343-351

  Luo, Xiang Hang ^a   Liao, Er Yuan ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Differentiation; Estriol; Osteoblast; Proliferation

Indexed keywords

ALKALINE PHOSPHATASE; ANTIESTROGEN; ESTRADIOL; ESTRIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FULVESTRANT; OSTEOCALCIN; THYMIDINE; TRITIUM;

ARTICLE; CELL COUNT; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; OSTEOBLAST; PRIORITY JOURNAL; WESTERN BLOTTING;

ALKALINE PHOSPHATASE; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; ESTRIOL; ESTROGEN RECEPTOR MODULATORS; GENE EXPRESSION; HUMANS; OSTEOBLASTS; OSTEOCALCIN; RECEPTORS, ESTROGEN; THYMIDINE;

EID: 0141869975     PISSN: 07435800     EISSN: None     Source Type: Journal    
DOI: 10.1081/ERC-120025041     Document Type: Article

References (19)

1. Rodan GA, Martin TJ. Therapeutic approaches to bone diseases. Science 2000; 289:1508-1514.
2. Reginster JY, Bruyere O, Audran M. Do estrogens effectively prevent osteoporosis-related fractures? Calcif Tissue Int 2000; 67:191-194.
3. Head KA. Estriol: safety and efficacy. Altern Med Rev 1998; 3:101-113.
4. Minaguchi H, Uemura T, Shirasu K, Sato A, Tsukikawa S, Ibuki Y, Mizunuma H, Aso T, Koyama T, Nozawa S, Ohta H, Ikeda T, Kusuhara K, Ochiai K, Kinoshita T. Effect of estriol on bone loss in postmenopausal Japanese women: a multicenter prospective open study. J Obstet Gynaecol Res 1996; 22:259-265.
5. Liao EY, Luo XH, Wang WB, Wu XP, Zhou HD, Dai RC, Liao HJ, Yang C. Effects of different nylestriol/levonorgestrel dosages on bone metabolism in female Sprague-Dawley rats with retinoic acid-induced osteoporosis. Endocrine Research 2003; 29(1):21-40.
6. Liao EY, Luo XH, Deng XG, Wu XP, Liao HJ, Wang PF, Mao JP, Zhu XP, Huang G, Wei QY. The effect of low dose nylestriol-levonorgestrel replacement therapy on bone mineral density in women with postmenopausal osteoporosis. Endocrine Research 2003; 29(2):217-226.
7. Luo XH, Liao EY, Su X. Comparison of the effects of 17beta-E2 and progesterone on the expression of osteoprotegerin in normal human osteoblast-like cells. J Endocrinol Invest 2002; 25:785-790.
8. Liao EY, Luo XH. Effect of Effects of 17β-estradiol on the expression of matrix metalloproteinase-1, -2 and tissue inhibitor of metalloproteinase-1 in human osteoblast-like cells cultures. Endocrine 2001; 15:291-295.
9. Luo XH, Liao EY. Progesterone differentially regulates the membrane-type matrix metalloproteinase-1 (MT1-MMP) compartment of proMMP-2 activation in MG-63 cells. Horm Metab Res 2001; 33:383-388.
10. Nishibe A, Morimoto S, Hirota K, Yasuda O, Ikegami H, Yamamoto T, Fukuo K, Onishi T, Ogihara T. Effect of estriol and bone mineral density of lumbar vertebrae in elderly and postmenopausal women. Nippon Ronen Igakkai Zasshi 1996; 33:353-359.
11. Nozaki M, Hashimoto K, Inoue Y, Sano M, Nakano H. Usefulness of estriol for the treatment of bone loss in postmenopausal women. Nippon Sanka Fujinka Gakkai Zasshi 1996; 48:83-88.
12. Cheng GJ, Liu JL, Zhang Q, Ye HF, Wang ZQ, Pan HP. Prospective double-blind study of CEE3 in peri- and postmenopausal women: effects on bone loss and lipoprotein lipids. Chin Med J 1992; 105:929-933.
13. Liu HW, Yang SZ, Xu KH. Prevention of osteoporosis following ovariectomy in rats with nylestriol. J West China Med Univ 1993; 24:40-44.
14. Zhu M, Liu ZP, Zhang X. Study on the effects of nylestriol on tibia in ovary-removed rats. Chin J Obstet and Gynecol 1999; 34:86-89.
15. Shi WB, Du N, Fu SC. Bone morphometry changes caused by nylestriol in ovary-removed rabbits. Chin J Obstet and Gynecol 1997; 32:544-547.
16. Katzenellenbogen BS. Biology and receptor interactions of estriol and estriol derivatives in vitro and in vivo. J Steroid Biochem 1984; 20:1033-1037.
17. Russo LA, Calabro SP, Filler TA, Carey DJ, Gardner RM. In vivo regulation of syndecan-3 expression in the rat uterus by 17 beta-estradiol. J Biol Chem 2001; 276:686-692.
18. Jones PS, Parrott E, White INH. Activation of transcription by estrogen receptor α and β is cell type- and promoter-dependent. J Biol Chem 1999; 274:32008-32014.
19. Melamed M, Castano E, Notides AC, Sasson S. Molecular and kinetic basis for the mixed agonist/antagonist activity of estriol. Mol Endocrinol 1997; 11:1868-1878.