CLOCK gene T3111C polymorphism is associated with Japanese schizophrenics: A preliminary study

European Neuropsychopharmacology

Volumn 17, Issue 4, 2007, Pages 273-276

  Takao, T ^a   Tachikawa, H ^b   Kawanishi, Y ^a   Mizukami, K ^a   Asada, T ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b Ibaraki Prefectural Mental Health and Welfare Centre   (Japan)

Author keywords

Circadian rhythm; ; CLOCK gene; ; Dopamine; ; Negative symptom; Schizophrenia; ; T3111C polymorphism;

Indexed keywords

DOPAMINE;

ADULT; ALLELE; ARTICLE; CIRCADIAN RHYTHM; CLINICAL FEATURE; CLOCK GENE; CONTROLLED STUDY; DISEASE ASSOCIATION; DOPAMINERGIC SYSTEM; FEMALE; GENE; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; JAPAN; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; DNA MUTATIONAL ANALYSIS; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; JAPAN; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; SCHIZOPHRENIA; STATISTICS, NONPARAMETRIC; TRANS-ACTIVATORS;

EID: 33846349201     PISSN: 0924977X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2006.09.002     Document Type: Article

References (25)

1. American Psychiatric Association. Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) (1997), American Psychiatric Association, Washington, DC
2. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) (2000), American Psychiatric Association, Washington, DC
3. Bailer U., Wiesegger G., Leisch F., Fuchs K., Leitner I., Letmaier M., Konstantinidis A., Stastny J., Sieghart W., Hornik K., Mitterauer B., Kasper S., and Aschauer H.N. No association of clock gene T3111C polymorphism and affective disorders. Eur. Neuropsychopharmacol. 15 1 (2005) 51-55
4. Benedetti F., Serretti A., Colombo C., Barbini B., Lorenzi C., Campori E., and Smeraldi E. Influence of CLOCK gene polymorphism on circadian mood fluctuation and illness recurrence in bipolar depression. Am. J. Med. Genet., B Neuropsychiatr. Genet. 123 1 (2003) 23-26
5. Desan P.H., Oren D.A., Malison R., Price L.H., Rosenbaum J., Smollar J., Charney D.S., and Gelernter J. Genetic polymorphism at the CLOCK gene locus and major depression. Am. J. Med. Genet. 96 3 (2000) 418-421 (Jun 12)
6. Iwase T., Kajimura N., Uchiyama M., Ebisawa T., Yoshimura K., Kamei Y., Shibui K., Kim K., Kudo Y., Katoh M., Watanabe T., Nakajima T., Ozeki Y., Sugishita M., Hori T., Ikeda M., Toyoshima R., Inoue Y., Yamada N., Mishima K., Nomura M., Ozaki N., Okawa M., Takahashi K., and Yamauchi T. Mutation screening of the human Clock gene in circadian rhythm sleep disorders. Psychiatry Res. 109 2 (2002) 121-128 (Mar 15)
7. Katzenberg D., Young T., Finn L., Lin L., King D.P., Takahashi J.S., and Mignot E. A CLOCK polymorphism associated with human diurnal preference. Sleep 21 6 (1998) 569-576 (Sep 15)
8. Lattuada E., Cavallaro R., Benedetti F., Cocchi F., Lorenzi C., and Smeraldi E. Genetic dissection of drug effects in clinical practice: CLOCK gene and clozapine-induced diurnal sleepiness. Neurosci. Lett. 367 2 (2004) 152-155
9. Lauer C.J., Schreiber W., Pollmacher T., Holsboer F., and Krieg J.C. Sleep in schizophrenia: a polysomnographic study on drug-naive patients. Neuropsychopharmacology 16 1 (1997) 51-60
10. Mansour H.A., Wood J., Logue T., Chowdari K.V., Dayal M., Kupfer D.J., Monk T.H., Devlin B., and Nimgaonkar V.L. Association study of eight circadian genes with bipolar I disorder, schizoaffective disorder and schizophrenia. Genes. Brain Behav. 5 2 (2006) 150-157
11. Martin J.L., Jeste D.V., and Ancoli-Israel S. Older schizophrenia patients have more disrupted sleep and circadian rhythms than age-matched comparison subjects. J. Psychiatr. Res. 39 3 (2005) 251-259
12. McClung C.A., Sidiropoulou K., Vitaterna M., Takahashi J.S., White F.J., Cooper D.C., and Nestler E.J. Regulation of dopaminergic transmission and cocaine reward by the Clock gene. Proc. Natl. Acad. Sci. U. S. A. 102 26 (2005) 9377-9381
13. Mignone F., Gissi C., Liuni S., and Pesole G. Untranslated regions of mRNAs. Genome Biol. 3 3 (2002) (REVIEWS0004)
14. Online sources: http://www.ncbi.nlm.nih.gov/SNP (May 2006).
15. Rao M.L., Gross G., Strebel B., Halaris A., Huber G., Braunig P., and Marler M. Circadian rhythm of tryptophan, serotonin, melatonin, and pituitary hormones in schizophrenia. Biol. Psychiatry 35 3 (1994) 151-163 (Feb 1)
16. Reppert S.M., and Weaver D.R. Coordination of circadian timing in mammals. Nature 418 6901 (2002) 935-941
17. Rotenberg V.S., Indurski P., Kimhi R., Hadjez J., Gutman Y., Shamir E., Barak Y., and Elizur A. The relationship between objective sleep variables and subjective sleep estimation in schizophrenia. Int. J. Psychiatry Clin. Pract. 4 (2000) 63-67
18. Serretti A., Benedetti F., Mandelli L., Lorenzi C., Pirovano A., Colombo C., and Smeraldi E. Genetic dissection of psychopathological symptoms: insomnia in mood disorders and CLOCK gene polymorphism. Am. J. Med. Genet., B Neuropsychiatr. Genet. 121 1 (2003) 35-38 (Aug 15)
19. Serretti A., Cusin C., Benedetti F., Mandelli L., Pirovano A., Zanardi R., Colombo C., and Smeraldi E. Insomnia improvement during antidepressant treatment and CLOCK gene polymorphism. Am. J. Med. Genet., B Neuropsychiatr. Genet. 137 1 (2005) 36-39
20. Steeves T.D., King D.P., Zhao Y., Sangoram A.M., Du F., Bowcock A.M., Moore R.Y., and Takahashi J.S. Molecular cloning and characterization of the human CLOCK gene: expression in the suprachiasmatic nuclei. Genomics 57 2 (1999) 189-200 (Apr 15)
21. Tandon R., Shipley J.E., Taylor S., Greden J.F., Eiser A., DeQuardo J., and Goodson J. Electroencephalographic sleep abnormalities in schizophrenia: relationship to positive/negative symptoms and prior neuroleptic treatment. Arch. Gen. Psychiatry 49 3 (1992) 185-194
22. Turek F.W., and Kolker D.E. The discovery of circadian clock genes and the use of similar strategies to discover unknown genes underlying complex behaviors and brain disorders (Review). Eur. Neuropsychopharmacol. 11 6 (2001) 475-482
23. Uz T., Ahmed R., Akhisaroglu M., Kurtuncu M., Imbesi M., Dirim Arslan A., and Manev H. Effect of fluoxetine and cocaine on the expression of clock genes in the mouse hippocampus and striatum. Neuroscience 134 4 (2005) 1309-1316
24. Wirz-Justice A., Haug H.J., and Cajochen C. Disturbed circadian rest-activity cycles in schizophrenia patients: an effect of drugs?. Schizophr. Bull. 27 3 (2001) 497-502
25. Yujnovsky I., Hirayama J., Doi M., Borrelli E., and Sassone-Corsi P. Signaling mediated by the dopamine D2 receptor potentiates circadian regulation by CLOCK:BMAL1. Proc. Natl. Acad. Sci. U. S. A. 103 16 (2006) 6386-6391 (Apr 18)