메뉴 건너뛰기




Volumn 401, Issue 1, 2007, Pages 309-316

Pharmacological profiling of the Dictyostelium adenylate cyclases ACA, ACB and ACG

Author keywords

Adenylate cyclase; Caffeine; cAMP; Dictyostelium discoideum; Enzyme specific inhibitor; P site inhibition

Indexed keywords

ADENYLATE CYCLASE; CAFFEINE; CAMP; DICTYOSTELIUM DISCOIDEUM; ENZYME-SPECIFIC INHIBITOR; P-SITE INHIBITION;

EID: 33846308904     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20060880     Document Type: Article
Times cited : (26)

References (44)
  • 2
    • 0033279835 scopus 로고    scopus 로고
    • Integration of signaling networks that regulate Dictyostelium differentiation
    • Aubry, L. and Firtel, R. (1999) Integration of signaling networks that regulate Dictyostelium differentiation. Annu. Rev. Cell Dev. Biol. 15, 469-517
    • (1999) Annu. Rev. Cell Dev. Biol , vol.15 , pp. 469-517
    • Aubry, L.1    Firtel, R.2
  • 4
    • 0026504354 scopus 로고    scopus 로고
    • Pitt, G. S., Milona, N., Borleis, J., Lin, K. C., Reed, R. R. and Devreotes, P. N. (1992) Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium development. Cell 69, 305-315
    • Pitt, G. S., Milona, N., Borleis, J., Lin, K. C., Reed, R. R. and Devreotes, P. N. (1992) Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium development. Cell 69, 305-315
  • 5
    • 2642689663 scopus 로고    scopus 로고
    • Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS
    • Tesmer, J. J., Sunahara, R. K., Gilman, A. G. and Sprang, S. R. (1997) Crystal structure of the catalytic domains of adenylyl cyclase in a complex with Gsalpha.GTPgammaS. Science 278, 1907-1916
    • (1997) Science , vol.278 , pp. 1907-1916
    • Tesmer, J.J.1    Sunahara, R.K.2    Gilman, A.G.3    Sprang, S.R.4
  • 6
    • 12544249887 scopus 로고    scopus 로고
    • The PI3K-mediated activation of CRAC independently regulates adenylyl cyclase activation and chemotaxis
    • Comer, F. I., Lippincott, C. K., Masbad, J. J. and Parent, C. A. (2005) The PI3K-mediated activation of CRAC independently regulates adenylyl cyclase activation and chemotaxis. Curr. Biol. 15, 134-139
    • (2005) Curr. Biol , vol.15 , pp. 134-139
    • Comer, F.I.1    Lippincott, C.K.2    Masbad, J.J.3    Parent, C.A.4
  • 8
    • 1542313957 scopus 로고    scopus 로고
    • Adenylyl cyclase 6 is activated by an intramolecular osmosensor
    • Saran, S. and Schaap, P. (2004) Adenylyl cyclase 6 is activated by an intramolecular osmosensor. Mol. Biol. Cell 15, 1479-1486
    • (2004) Mol. Biol. Cell , vol.15 , pp. 1479-1486
    • Saran, S.1    Schaap, P.2
  • 9
    • 0032553329 scopus 로고    scopus 로고
    • A novel adenylyl cyclase detected in rapidly developing mutants of Dictyostelium
    • Kim, H. J., Chang, W. T., Meima, M., Gross, J. D. and Schaap, P. (1998) A novel adenylyl cyclase detected in rapidly developing mutants of Dictyostelium. J. Biol. Chem. 273, 30859-30862
    • (1998) J. Biol. Chem , vol.273 , pp. 30859-30862
    • Kim, H.J.1    Chang, W.T.2    Meima, M.3    Gross, J.D.4    Schaap, P.5
  • 10
    • 0343384175 scopus 로고    scopus 로고
    • An adenylyl cyclase that functions during late development of Dictyostelium
    • Soderbom, F., Anjard, C., Iranfar, N., Fuller, D. and Loomis, W. F. (1999) An adenylyl cyclase that functions during late development of Dictyostelium. Development 126, 5463-5471
    • (1999) Development , vol.126 , pp. 5463-5471
    • Soderbom, F.1    Anjard, C.2    Iranfar, N.3    Fuller, D.4    Loomis, W.F.5
  • 11
    • 0041315748 scopus 로고    scopus 로고
    • A defined subset of adenylyl cyclases is regulated by bicarbonate ion
    • Cann, M. J., Hammer, A., Zhou, J. and Kanacher, T. (2003) A defined subset of adenylyl cyclases is regulated by bicarbonate ion. J. Biol. Chem. 278, 35033-35038
    • (2003) J. Biol. Chem , vol.278 , pp. 35033-35038
    • Cann, M.J.1    Hammer, A.2    Zhou, J.3    Kanacher, T.4
  • 12
    • 0029088825 scopus 로고
    • Isolation of inactive and G protein-resistant adenylyl cyclase mutants using random mutagenesis
    • Parent, C. A. and Devreotes, P. N. (1995) Isolation of inactive and G protein-resistant adenylyl cyclase mutants using random mutagenesis. J. Biol. Chem. 270, 22693-22696
    • (1995) J. Biol. Chem , vol.270 , pp. 22693-22696
    • Parent, C.A.1    Devreotes, P.N.2
  • 13
    • 0029770441 scopus 로고    scopus 로고
    • Constitutitively active adenylyl cyclase mutant requires neither G proteins nor cytosolic regulators
    • Parent, C. A. and Devreotes, P. N. (1996) Constitutitively active adenylyl cyclase mutant requires neither G proteins nor cytosolic regulators. J. Biol. Chem. 271, 18333-18336
    • (1996) J. Biol. Chem , vol.271 , pp. 18333-18336
    • Parent, C.A.1    Devreotes, P.N.2
  • 14
    • 0030901637 scopus 로고    scopus 로고
    • Structure of the adenylyl cyclase catalytic core
    • Zhang, G., Liu, Y., Ruoho, A. E. and Hurley, J. H. (1997) Structure of the adenylyl cyclase catalytic core. Nature 386, 247-253
    • (1997) Nature , vol.386 , pp. 247-253
    • Zhang, G.1    Liu, Y.2    Ruoho, A.E.3    Hurley, J.H.4
  • 16
    • 0020948592 scopus 로고
    • Forskolin does not activate cyclic AMP synthesis in Dictyostelium discoideum in vivo or in vitro
    • Brenner, M. and Padh, H. (1983) Forskolin does not activate cyclic AMP synthesis in Dictyostelium discoideum in vivo or in vitro. J. Cycl. Nucl. Protein Phosphor. Res. 9, 297-303
    • (1983) J. Cycl. Nucl. Protein Phosphor. Res , vol.9 , pp. 297-303
    • Brenner, M.1    Padh, H.2
  • 17
    • 0021326961 scopus 로고
    • Caffeine blocks activation of cyclic AMP synthesis in Dictyostelium discoideum
    • Brenner, M. and Thoms, S. D. (1984) Caffeine blocks activation of cyclic AMP synthesis in Dictyostelium discoideum. Dev. Biol. 101, 136-146
    • (1984) Dev. Biol , vol.101 , pp. 136-146
    • Brenner, M.1    Thoms, S.D.2
  • 18
    • 0021715183 scopus 로고
    • Adenosine and its derivatives inhibit the cAMP signaling response in Dictyostelium discoideum
    • Theibert, A. and Devreotes, P. (1984) Adenosine and its derivatives inhibit the cAMP signaling response in Dictyostelium discoideum. Dev. Biol. 106, 166-173
    • (1984) Dev. Biol , vol.106 , pp. 166-173
    • Theibert, A.1    Devreotes, P.2
  • 19
    • 0023099106 scopus 로고
    • Regulation of Dictyostelium discoideum adenylate cyclase by manganese and adenosine analogs
    • Khachatrian, L., Klein, C. and Hewlett, A. (1987) Regulation of Dictyostelium discoideum adenylate cyclase by manganese and adenosine analogs. Biochim. Biophys. Acta 927, 235-246
    • (1987) Biochim. Biophys. Acta , vol.927 , pp. 235-246
    • Khachatrian, L.1    Klein, C.2    Hewlett, A.3
  • 20
    • 0038052595 scopus 로고
    • Specificity of adenosine inhibition of cAMP-induced responses in Dictyostelium resembles that of the P-site of higher organisms
    • Van Lockeren Campagne, M. M., Schaap, P. and Van Haastert, P. J. M. (1986) Specificity of adenosine inhibition of cAMP-induced responses in Dictyostelium resembles that of the P-site of higher organisms. Dev. Biol. 117, 245-251
    • (1986) Dev. Biol , vol.117 , pp. 245-251
    • Van Lockeren Campagne, M.M.1    Schaap, P.2    Van Haastert, P.J.M.3
  • 21
    • 0014200325 scopus 로고    scopus 로고
    • 20a Sussman, R. and Sussman, M. (1967) Cultivation of Dictyostelium discoideum in axenic medium. Biochem. Biophys. Res. Commun. 29, 53-55
    • 20a Sussman, R. and Sussman, M. (1967) Cultivation of Dictyostelium discoideum in axenic medium. Biochem. Biophys. Res. Commun. 29, 53-55
  • 22
    • 0037853211 scopus 로고    scopus 로고
    • Characterization of a cAMP-stimulated cAMP phosphodiesterase in Dictyostelium discoideum
    • Meima, M. E., Weening, K. E. and Schaap, P. (2003) Characterization of a cAMP-stimulated cAMP phosphodiesterase in Dictyostelium discoideum. J. Biol. Chem. 278, 14355-14362
    • (2003) J. Biol. Chem , vol.278 , pp. 14355-14362
    • Meima, M.E.1    Weening, K.E.2    Schaap, P.3
  • 23
    • 0032525229 scopus 로고    scopus 로고
    • An intersection of the cAMP/PKA and two-component signal transduction systems in Dictyostelium
    • Thomason, P. A., Traynor, D., Cavet, G., Chang, W.-T., Harwood, A. J. and Kay, R. R. (1998) An intersection of the cAMP/PKA and two-component signal transduction systems in Dictyostelium. EMBO J. 17, 2838-2845
    • (1998) EMBO J , vol.17 , pp. 2838-2845
    • Thomason, P.A.1    Traynor, D.2    Cavet, G.3    Chang, W.-T.4    Harwood, A.J.5    Kay, R.R.6
  • 24
    • 0033179521 scopus 로고    scopus 로고
    • Fingerprinting of adenylyl cyclase activities during Dictyostelium development indicates a dominant role for adenylyl cyclase B in terminal differentiation
    • Meima, M. E. and Schaap, P. (1999) Fingerprinting of adenylyl cyclase activities during Dictyostelium development indicates a dominant role for adenylyl cyclase B in terminal differentiation. Dev. Biol. 212, 182-190
    • (1999) Dev. Biol , vol.212 , pp. 182-190
    • Meima, M.E.1    Schaap, P.2
  • 25
    • 16444381703 scopus 로고    scopus 로고
    • Caffeine and the dopaminergic system
    • Cauli, O. and Morelli, M. (2005) Caffeine and the dopaminergic system. Behav. Pharmacol. 16, 63-77
    • (2005) Behav. Pharmacol , vol.16 , pp. 63-77
    • Cauli, O.1    Morelli, M.2
  • 26
    • 0017274843 scopus 로고
    • Inhibitors and activators of cyclic nucleotide phosphodiesterase
    • Chasin, M. and Harris, D. N. (1976) Inhibitors and activators of cyclic nucleotide phosphodiesterase. Adv. Cycl. Nucl. Res. 7, 225-264
    • (1976) Adv. Cycl. Nucl. Res , vol.7 , pp. 225-264
    • Chasin, M.1    Harris, D.N.2
  • 27
    • 0028912336 scopus 로고    scopus 로고
    • 2+ levels. Dev. Biol. 168, 179-188
    • 2+ levels. Dev. Biol. 168, 179-188
  • 28
    • 0015492635 scopus 로고
    • Phosphodiesterase in Dictyostelium discoideum and the chemotactic response to cyclic adenosine monophosphate
    • Pannbacker, R. G. and Bravard, L. J. (1972) Phosphodiesterase in Dictyostelium discoideum and the chemotactic response to cyclic adenosine monophosphate. Science 175, 1014-1015
    • (1972) Science , vol.175 , pp. 1014-1015
    • Pannbacker, R.G.1    Bravard, L.J.2
  • 29
    • 33746002298 scopus 로고    scopus 로고
    • DdPDE4, a novel cAMP-specific phosphodiesterase at the surface of Dictyostelium cells
    • Bader, S., Kortholt, A., Snippe, H. and Van Haastert, P. J. (2006) DdPDE4, a novel cAMP-specific phosphodiesterase at the surface of Dictyostelium cells. J. Biol. Chem. 281, 20018-20026
    • (2006) J. Biol. Chem , vol.281 , pp. 20018-20026
    • Bader, S.1    Kortholt, A.2    Snippe, H.3    Van Haastert, P.J.4
  • 30
    • 0020360523 scopus 로고
    • Inhibition by adenosine of aggregation centre initiation and cyclic AMP binding in Dictyostelium
    • Newell, P. C. and Ross, F. M. (1982) Inhibition by adenosine of aggregation centre initiation and cyclic AMP binding in Dictyostelium. J. Gen. Microbiol. 128, 2715-2724
    • (1982) J. Gen. Microbiol , vol.128 , pp. 2715-2724
    • Newell, P.C.1    Ross, F.M.2
  • 31
    • 0030578401 scopus 로고    scopus 로고
    • Extracellular cAMP depletion triggers stalk gene expression in Dictyostelium: Disparities in developmental timing and dose dependency indicate that prespore induction and stalk repression by cAMP are mediated by separate signaling pathways
    • Soede, R. D. M., Hopper, N. A., Williams, J. G. and Schaap, P. (1996) Extracellular cAMP depletion triggers stalk gene expression in Dictyostelium: disparities in developmental timing and dose dependency indicate that prespore induction and stalk repression by cAMP are mediated by separate signaling pathways. Dev. Biol. 177, 152-159
    • (1996) Dev. Biol , vol.177 , pp. 152-159
    • Soede, R.D.M.1    Hopper, N.A.2    Williams, J.G.3    Schaap, P.4
  • 32
    • 3543127047 scopus 로고    scopus 로고
    • Functional promiscuity of gene regulation by serpentine receptors in Dictyostelium discoideum
    • Verkerke-VanWijk, I., Kim, J. Y., Brandt, R., Devreotes, P. N. and Schaap, P. (1998) Functional promiscuity of gene regulation by serpentine receptors in Dictyostelium discoideum. Mol. Cell. Biol. 18, 5744-5749
    • (1998) Mol. Cell. Biol , vol.18 , pp. 5744-5749
    • Verkerke-VanWijk, I.1    Kim, J.Y.2    Brandt, R.3    Devreotes, P.N.4    Schaap, P.5
  • 33
    • 0035034495 scopus 로고    scopus 로고
    • Inducible nuclear translocation of a STAT protein in Dictyostelium prespore cells; implications for morphogenesis and cell-type regulation
    • Dormann, D., Abe, T., Weijer, C. J. and Williams, J. (2001) Inducible nuclear translocation of a STAT protein in Dictyostelium prespore cells; implications for morphogenesis and cell-type regulation. Development 128, 1081-1088
    • (2001) Development , vol.128 , pp. 1081-1088
    • Dormann, D.1    Abe, T.2    Weijer, C.J.3    Williams, J.4
  • 34
    • 0024370049 scopus 로고
    • Cation and structural requirements for P site-mediated inhibition of adenylate cyclase
    • Johnson, R. A., Yeung, S. M., Stubner, D., Bushfield, M. and Shoshani, I. (1989) Cation and structural requirements for P site-mediated inhibition of adenylate cyclase. Mol. Pharmacol. 35, 681-688
    • (1989) Mol. Pharmacol , vol.35 , pp. 681-688
    • Johnson, R.A.1    Yeung, S.M.2    Stubner, D.3    Bushfield, M.4    Shoshani, I.5
  • 35
    • 0017636509 scopus 로고
    • Two distinct adenosine-sensitive sites on adenylate cyclase
    • Londos, C. and Wolff, J. (1977) Two distinct adenosine-sensitive sites on adenylate cyclase. Proc. Natl. Acad. Sci. U.S.A. 74, 5482-5486
    • (1977) Proc. Natl. Acad. Sci. U.S.A , vol.74 , pp. 5482-5486
    • Londos, C.1    Wolff, J.2
  • 36
    • 0035209620 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
    • Fredholm, B. B., IJzerman, A. P., Jacobson, K. A., Klotz, K.-N. and Linden, J. (2001) International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol. Rev. 53, 527-552
    • (2001) Pharmacol. Rev , vol.53 , pp. 527-552
    • Fredholm, B.B.1    IJzerman, A.P.2    Jacobson, K.A.3    Klotz, K.-N.4    Linden, J.5
  • 39
    • 0018770337 scopus 로고
    • Inhibition of adenylate cyclase in human blood platelets by 9-substituted adenine derivatives
    • Harris, D. N., Asaad, M. M., Phillips, M. B., Goldenberg, H. J. and Antonaccio, M. J. (1979) Inhibition of adenylate cyclase in human blood platelets by 9-substituted adenine derivatives. J. Cycl. Nucl. Res. 5, 125-134
    • (1979) J. Cycl. Nucl. Res , vol.5 , pp. 125-134
    • Harris, D.N.1    Asaad, M.M.2    Phillips, M.B.3    Goldenberg, H.J.4    Antonaccio, M.J.5
  • 40
    • 3042604812 scopus 로고    scopus 로고
    • Tyrphostins are inhibitors of guanylyl and adenylyl cyclases
    • Jaleel, M., Shenoy, A. R. and Visweswariah, S. S. (2004) Tyrphostins are inhibitors of guanylyl and adenylyl cyclases. Biochemistry 43, 8247-8255
    • (2004) Biochemistry , vol.43 , pp. 8247-8255
    • Jaleel, M.1    Shenoy, A.R.2    Visweswariah, S.S.3
  • 41
    • 0024366979 scopus 로고
    • Digital image processing of optical density wave propagation in Dictyostelium discoideum and analysis of the effects of caffeine and ammonia
    • Siegert, F. and Weijer, C. (1989) Digital image processing of optical density wave propagation in Dictyostelium discoideum and analysis of the effects of caffeine and ammonia. J. Cell Sci. 93, 325-335
    • (1989) J. Cell Sci , vol.93 , pp. 325-335
    • Siegert, F.1    Weijer, C.2
  • 42
    • 0025763969 scopus 로고
    • DC6, a novel type of Dictyostelium discoideum gene regulated by secreted factors but not by cAMP
    • Yoshida, H., Yamada, Y. and Okamoto, K. (1991) DC6, a novel type of Dictyostelium discoideum gene regulated by secreted factors but not by cAMP. Differentiation 46, 161-166
    • (1991) Differentiation , vol.46 , pp. 161-166
    • Yoshida, H.1    Yamada, Y.2    Okamoto, K.3
  • 43
    • 0028226670 scopus 로고
    • The effect of extracellular cyclic AMP on differentiation inducing factor (DIF)-dependent prestalk cell gene expression in monolayers of Dictyostelium is complex
    • So, J. S. and Weeks, G. (1994) The effect of extracellular cyclic AMP on differentiation inducing factor (DIF)-dependent prestalk cell gene expression in monolayers of Dictyostelium is complex. Differentiation 56, 131-135
    • (1994) Differentiation , vol.56 , pp. 131-135
    • So, J.S.1    Weeks, G.2
  • 44
    • 0023000293 scopus 로고
    • Surface receptor-mediated activation of adenylate cyclase in Dictyostelium
    • Theibert, A. and Devreotes, P. (1986) Surface receptor-mediated activation of adenylate cyclase in Dictyostelium. J. Biol. Chem. 261, 15121-15125
    • (1986) J. Biol. Chem , vol.261 , pp. 15121-15125
    • Theibert, A.1    Devreotes, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.