Sensitivity improvement of circular dichroism detection in HPLC by using a low-pass electronic noise filter: Application to the enantiomeric determination purity of a basic drug

Chirality

Volumn 19, Issue 2, 2007, Pages 106-113

  Lorin, Marie ^a   Delepee, Raphael ^a   Maurizot, Jean Claude ^b   Ribet, Jean Paul ^c   Morin, Philippe ^a  

^a UNIVERSITÉ D'ORLÉANS   (France)

^b CENTRE DE BIOPHYSIQUE MOLÉCULAIRE   (France)

^c INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

2 adrenoreceptor antagonist; Circular dichroism; Efaroxan; Enantiomeric purity; HPLC; Low pass electronic noise filter; Polysaccharide stationary phase; Quantitation

Indexed keywords

ALCOHOL; AMYLOSE; DIETHYLAMINE; EFAROXAN; HEXANE;

ARTICLE; CHEMICAL COMPOSITION; CIRCULAR DICHROISM; CONCENTRATION (PARAMETERS); DRUG PURITY; DRUG STRUCTURE; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SIGNAL NOISE RATIO; STEREOISOMERISM; ULTRAVIOLET SPECTROSCOPY;

ADRENERGIC ALPHA-ANTAGONISTS; BENZOFURANS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; IMIDAZOLES; SENSITIVITY AND SPECIFICITY; STEREOISOMERISM;

EID: 33846295518     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.20352     Document Type: Article

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