Differential regional effects of methadone maintenance compared to heroin dependence on μ-opioid receptor desensitization in rat brain

Synapse

Volumn 61, Issue 3, 2007, Pages 176-184

  Martin, Thomas J ^a   Kahn, William R ^a   Xiao, Royu ^a   Childers, Steven R ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Autoradiography; Dependence; G protein coupling; Reinforcement; Self administration; Tolerance

Indexed keywords

DIAMORPHINE; ENDORPHIN; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; GUANINE NUCLEOTIDE BINDING PROTEIN; METHADONE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; SODIUM CHLORIDE;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; CORPUS STRIATUM; DESENSITIZATION; DRUG EFFICACY; DRUG INFUSION; DRUG SELF ADMINISTRATION; HEROIN DEPENDENCE; MAINTENANCE THERAPY; MALE; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAT; SUBICULAR NUCLEUS; SUBICULUM; THALAMUS;

ANIMALS; BINDING, COMPETITIVE; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; EATING; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HEROIN; HEROIN DEPENDENCE; INJECTIONS, INTRAVENOUS; MALE; METHADONE; NARCOTICS; RADIOLIGAND ASSAY; RATS; RATS, INBRED F344; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, OPIOID, MU; REINFORCEMENT (PSYCHOLOGY); SELF ADMINISTRATION;

EID: 33846226075     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20355     Document Type: Article

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