Pinusolide and 15-methoxypinusolidic acid attenuate the neurotoxic effect of staurosporine in primary cultures of rat cortical cells

British Journal of Pharmacology

Volumn 150, Issue 1, 2007, Pages 65-71

  Koo, K A ^a   Lee, M K ^a   Kim, S H ^a   Jeong, E J ^a   Kim, S Y ^b   Oh, T H ^b   Kim, Y C ^a  

^a Seoul National University   (South Korea)

^b Kyung Hee University   (South Korea)

Author keywords

15 methoxypinusolidic acid; Apoptosis; Biota orientalis; Neuroprotective activity; Pinusolide; Staurosporine

Indexed keywords

15 METHOXYPINUSOLIDIC ACID; ANTIOXIDANT; CALCIUM ION; CASPASE 3; CASPASE 7; LIPID; MALONALDEHYDE; PEROXIDE; PINUSOLIDE; REACTIVE OXYGEN METABOLITE; STAUROSPORINE; SUPEROXIDE DISMUTASE; TERPENOID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTICLE; BIOTA ORIENTALIS; BRAIN CELL; CALCIUM CELL LEVEL; CELL ACTIVITY; CELL LEVEL; CELL NUCLEUS MEMBRANE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOPLASM; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG ISOLATION; ENZYME ACTIVITY; ENZYME INHIBITION; FETUS; IN VITRO STUDY; LIPID PEROXIDATION; MEDICINAL PLANT; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT;

ANIMALS; CALCIUM; CASPASES; CELLS, CULTURED; CEREBRAL CORTEX; DITERPENES; ENZYME ACTIVATION; MALONDIALDEHYDE; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; STAUROSPORINE; SUPEROXIDE DISMUTASE;

EID: 33846219146     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706944     Document Type: Article

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