Ornithine transcarbamylase and arginase I deficiency are responsible for diminished urea cycle function in the human hepatoblastoma cell line HepG2

International Journal of Biochemistry and Cell Biology

Volumn 39, Issue 3, 2007, Pages 555-564

  Mavri Damelin, Demetra ^a   Eaton, Simon ^b   Damelin, Leonard H ^a   Rees, Myrddin ^c   Hodgson, Humphrey J F ^a   Selden, Clare ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c NORTH HAMPSHIRE HOSPITAL   (United Kingdom)

Author keywords

Arginase I; Bio artificial liver; Hepatocytes; HepG2; Urea cycle

Indexed keywords

AMMONIA; AMMONIUM CHLORIDE; ARGINASE; ARGINASE I; ARGININOSUCCINATE LYASE; ARGININOSUCCINATE SYNTHASE; CARBAMOYL PHOSPHATE SYNTHASE; CARBON 14; COMPLEMENTARY DNA; NITROGEN 15; ORNITHINE CARBAMOYLTRANSFERASE; UNCLASSIFIED DRUG; UREA;

ARGINOSUCCINATE LYASE GENE; ARGINOSUCCINATE SYNTHETASE GENE; ARTICLE; ARTIFICIAL LIVER; CARBAMOYL PHOSPHATE SYNTHASE I GENE; CELL FUNCTION; CELL STRAIN HEPG2; CHEMICAL ANALYSIS; CONTROLLED STUDY; CULTURE MEDIUM; CYTOMEGALOVIRUS; DETOXIFICATION; ENZYME ASSAY; ENZYME DEFICIENCY; GENE; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; ISOTOPE LABELING; LIVER CELL; MOLECULAR DYNAMICS; NUCLEOTIDE SEQUENCE; ORNITHINE TRANSCARBAMYLASE GENE; PROMOTER REGION; PROTEIN ANALYSIS; UREA CYCLE; WESTERN BLOTTING;

ARGINASE; BASE SEQUENCE; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; DNA PRIMERS; GENE EXPRESSION; HUMANS; LIVER NEOPLASMS; ORNITHINE CARBAMOYLTRANSFERASE; RECOMBINANT PROTEINS; TRANSFECTION; UREA;

EID: 33846200819     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2006.10.007     Document Type: Article

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