Destabilization of transthyretin by pathogenic mutations in the DE loop

Proteins: Structure, Function and Genetics

Volumn 66, Issue 3, 2007, Pages 716-725

  Takeuchi, Makoto ^a   Mizuguchi, Mineyuki ^a   Kouno, Takahide ^a   Shinohara, Yoshinori ^a   Aizawa, Tomoyasu ^b   Demura, Makoto ^b   Mori, Yoshihiro ^a   Shinoda, Hiroyuki ^a   Kawano, Keiichi ^a,b  

^a UNIVERSITY OF TOYAMA   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Amyloid; Familial amyloidotic polyneuropathy; Pathogenic mutation; Stability; Transthyretin

Indexed keywords

PREALBUMIN;

AMINO ACID SUBSTITUTION; CONFERENCE PAPER; DEUTERIUM HYDROGEN EXCHANGE; DIMERIZATION; ESCHERICHIA COLI; FAMILIAL AMYLOID POLYNEUROPATHY; GENE MUTATION; HUMAN; MOLECULAR STABILITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN STRUCTURE;

AMYLOID; CALORIMETRY, DIFFERENTIAL SCANNING; CIRCULAR DICHROISM; CLONING, MOLECULAR; DEUTERIUM; DIMERIZATION; DRUG STABILITY; ESCHERICHIA COLI; HUMANS; HYDROGEN; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MUTATION; PREALBUMIN; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; VARIATION (GENETICS);

EID: 33846189402     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.21252     Document Type: Conference Paper

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