Effect of p53 haploinsufficiency on melphalan-induced genotoxic effects in mouse bone marrow and peripheral blood

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 615, Issue 1-2, 2007, Pages 57-65

  Ranaldi, R ^a,c   Palma, S ^b   Tanzarella, C ^b   Lascialfari, A ^c   Cinelli, S ^c   Pacchierotti, F ^a  

^a ENEA   (Italy)

^b ROMA TRE UNIVERSITY   (Italy)

^c Research Toxicology Centre   (Italy)

Author keywords

Melphalan; Micronuclei; Mouse bone marrow; p53

Indexed keywords

CARCINOGEN; CROSS LINKING REAGENT; MELPHALAN; PROTEIN P53;

ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLOOD; BONE MARROW; CANCER SUSCEPTIBILITY; CELL CYCLE; CELL DIVISION; CENTROMERE; CHROMOSOME ANALYSIS; CHROMOSOME BREAKAGE; CHROMOSOME DAMAGE; CHROMOSOME LOSS; CONTROLLED STUDY; CYTOTOXICITY; ERYTHROCYTE; GENE MUTATION; GENETIC SUSCEPTIBILITY; GENOTOXICITY; HAPLOTYPE; HETEROZYGOSITY; LONG TERM EXPOSURE; MALE; MICRONUCLEUS; MOUSE; NONHUMAN; NULL ALLELE; PHENOTYPE; PRIORITY JOURNAL; RETICULOCYTE; STATISTICAL SIGNIFICANCE; WILD TYPE;

ANIMALS; BLOOD CELLS; BONE MARROW CELLS; ERYTHROCYTES; GENE DELETION; GENES, P53; HETEROZYGOTE; MALE; MELPHALAN; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICRONUCLEUS TESTS; MUTAGENS; RETICULOCYTES;

ANIMALIA; MUS;

EID: 33846161601     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2006.10.001     Document Type: Article

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