Prevention of plasticity of endocannabinoid signaling inhibits persistent limbic hyperexcitability caused by developmental seizures

Journal of Neuroscience

Volumn 27, Issue 1, 2007, Pages 46-58

  Chen, Kang ^a   Neu, Axel ^a   Howard, Allyson L ^a   Földy, Csaba ^a   Echegoyen, Julio ^a   Hilgenberg, Lutz ^a   Smith, Martin ^a   Mackie, Ken ^b   Soltesz, Ivan ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cannabinoid; Development; Hippocampus; Inhibition; Plasticity; Seizure

Indexed keywords

AMPA RECEPTOR; CALCIUM; CANNABINOID 1 RECEPTOR; ENDOCANNABINOID; KAINIC ACID RECEPTOR; METABOTROPIC RECEPTOR;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CONTROLLED STUDY; DEPOLARIZATION; FEBRILE CONVULSION; GABAERGIC TRANSMISSION; HIPPOCAMPUS; IN VITRO STUDY; INHIBITORY POSTSYNAPTIC POTENTIAL; INTERNEURON; LIMBIC SYSTEM; NERVE CELL PLASTICITY; NONHUMAN; POST TETANIC POTENTIATION; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION; TETANUS; UPREGULATION;

ANIMALS; CELLS, CULTURED; LIMBIC SYSTEM; LONG-TERM POTENTIATION; NEURAL INHIBITION; NEURONAL PLASTICITY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, CANNABINOID, CB1; SEIZURES, FEBRILE; SIGNAL TRANSDUCTION;

EID: 33846152922     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3966-06.2007     Document Type: Article

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