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Volumn 22, Issue 1, 2007, Pages 55-62

Modulation of gene expression and DNA-adduct formation in precision-cut liver slices exposed to polycyclic aromatic hydrocarbons of different carcinogenic potency

Author keywords

[No Author keywords available]

Indexed keywords

1 METHYLPHENANTHRENE; BENZO[A]PYRENE; BENZO[B]FLUORANTHENE; DIBENZ[A,H]ANTHRACENE; DIBENZO[A,L]PYRENE; FLUORANTHENE; PHOSPHORUS 32; POLYCYCLIC AROMATIC HYDROCARBON; UNCLASSIFIED DRUG;

EID: 33846085244     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/gel058     Document Type: Article
Times cited : (19)

References (41)
  • 1
    • 0346062027 scopus 로고
    • Certain polycyclic aromatic hydrocarbons and heterocyclic compounds
    • IARC
    • IARC (1973) Certain polycyclic aromatic hydrocarbons and heterocyclic compounds. IARC Monogr. Eval. Carcinog. Risk Chem. Hum., 3, 1-271.
    • (1973) IARC Monogr. Eval. Carcinog. Risk Chem. Hum , vol.3 , pp. 1-271
  • 2
    • 0021007163 scopus 로고
    • Polynuclear aromatic compounds, Part 1, Chemical, environmental and experimental data
    • IARC
    • IARC (1983) Polynuclear aromatic compounds, Part 1, Chemical, environmental and experimental data. IARC Monogr. Eval. Carcinog. Risk Chem. Hum., 32, 1-453.
    • (1983) IARC Monogr. Eval. Carcinog. Risk Chem. Hum , vol.32 , pp. 1-453
  • 3
    • 0033955164 scopus 로고    scopus 로고
    • Formation of stable DNA adducts and apurinic sites upon metabolic activation of bay and fjord region polycyclic aromatic hydrocarbons in human cell cultures
    • Melendez-Colon,V.J., Luch,A., Seidel,A. and Baird,W.M. (2000) Formation of stable DNA adducts and apurinic sites upon metabolic activation of bay and fjord region polycyclic aromatic hydrocarbons in human cell cultures. Chem. Res. Toxicol., 13, 10-17.
    • (2000) Chem. Res. Toxicol , vol.13 , pp. 10-17
    • Melendez-Colon, V.J.1    Luch, A.2    Seidel, A.3    Baird, W.M.4
  • 4
    • 20444412643 scopus 로고    scopus 로고
    • Metabolic activation of polycyclic and heterocyclic aromatic hydrocarbons and DNA damage: A review
    • Xue,W. and Warshawsky,D. (2005) Metabolic activation of polycyclic and heterocyclic aromatic hydrocarbons and DNA damage: a review. Toxicol. Appl. Pharmacol., 206, 73-93.
    • (2005) Toxicol. Appl. Pharmacol , vol.206 , pp. 73-93
    • Xue, W.1    Warshawsky, D.2
  • 5
    • 0028967218 scopus 로고
    • Adenomas induced by polycyclic aromatic hydrocarbons in strain A/J mouse lung correlate with time-integrated DNA adduct levels
    • Ross,J.A., Nelson,G.B., Wilson,K.H., Rabinowitz,J.R., Galati,A., Stoner,G.D., Nesnow,S. and Mass,M.J. (1995) Adenomas induced by polycyclic aromatic hydrocarbons in strain A/J mouse lung correlate with time-integrated DNA adduct levels. Cancer Res., 55, 1039-1044.
    • (1995) Cancer Res , vol.55 , pp. 1039-1044
    • Ross, J.A.1    Nelson, G.B.2    Wilson, K.H.3    Rabinowitz, J.R.4    Galati, A.5    Stoner, G.D.6    Nesnow, S.7    Mass, M.J.8
  • 6
    • 0032565541 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbon-DNA adducts in humans: Relevance as biomarkers for exposure and cancer risk
    • Kriek,E., Rojas,M., Alexandrov,K. and Bartsch,H. (1998) Polycyclic aromatic hydrocarbon-DNA adducts in humans: relevance as biomarkers for exposure and cancer risk. Mutat Res., 400, 215-231.
    • (1998) Mutat Res , vol.400 , pp. 215-231
    • Kriek, E.1    Rojas, M.2    Alexandrov, K.3    Bartsch, H.4
  • 8
    • 0033025864 scopus 로고    scopus 로고
    • DNA adduct formation and persistence in rat tissues following exposure to the mammary carcinogen dibenzo[a,l]pyrene
    • Arif,J.M., Smith,W.A. and Gupta,R.C. (1999) DNA adduct formation and persistence in rat tissues following exposure to the mammary carcinogen dibenzo[a,l]pyrene. Carcinogenesis, 20, 1147-1150.
    • (1999) Carcinogenesis , vol.20 , pp. 1147-1150
    • Arif, J.M.1    Smith, W.A.2    Gupta, R.C.3
  • 9
    • 0027138898 scopus 로고
    • Recoveries of DNA adducts of polycyclic aromatic hydrocarbons in the 32P-postlabelling assay
    • Segerback,D. and Vodicka,P. (1993) Recoveries of DNA adducts of polycyclic aromatic hydrocarbons in the 32P-postlabelling assay. Carcinogenesis, 14, 2463-2469.
    • (1993) Carcinogenesis , vol.14 , pp. 2463-2469
    • Segerback, D.1    Vodicka, P.2
  • 10
    • 1142275258 scopus 로고    scopus 로고
    • Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1
    • Shimada,T. and Fujii-Kuriyama,Y. (2004) Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1. Cancer Sci., 95, 1-6.
    • (2004) Cancer Sci , vol.95 , pp. 1-6
    • Shimada, T.1    Fujii-Kuriyama, Y.2
  • 11
    • 0037440941 scopus 로고    scopus 로고
    • Tissue-specific induction of cytochromes P450 1A1 and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in engineered C57BL/6J mice of arylhydrocarbon receptor gene
    • Shimada,T., Sugie,A., Shindo,M., Nakajima,T., Azuma,E., Hashimoto,M. and Inoue,K. (2003) Tissue-specific induction of cytochromes P450 1A1 and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in engineered C57BL/6J mice of arylhydrocarbon receptor gene. Toxicol. Appl. Pharmacol., 187, 1-10.
    • (2003) Toxicol. Appl. Pharmacol , vol.187 , pp. 1-10
    • Shimada, T.1    Sugie, A.2    Shindo, M.3    Nakajima, T.4    Azuma, E.5    Hashimoto, M.6    Inoue, K.7
  • 12
    • 0032832051 scopus 로고    scopus 로고
    • Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites
    • Melendez-Colon,V.J., Luch,A., Seidel,A. and Baird,W.M. (1999) Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites. Carcinogenesis, 20, 1885-1891.
    • (1999) Carcinogenesis , vol.20 , pp. 1885-1891
    • Melendez-Colon, V.J.1    Luch, A.2    Seidel, A.3    Baird, W.M.4
  • 13
    • 0035909494 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro reporter gene assay
    • Machala,M., Vondracek,J., Blaha,L., Ciganek,M. and Neca,J.V. (2001) Aryl hydrocarbon receptor-mediated activity of mutagenic polycyclic aromatic hydrocarbons determined using in vitro reporter gene assay. Mutat Res., 497, 49-62.
    • (2001) Mutat Res , vol.497 , pp. 49-62
    • Machala, M.1    Vondracek, J.2    Blaha, L.3    Ciganek, M.4    Neca, J.V.5
  • 14
    • 2442428432 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbons induce both apoptotic and anti-apoptotic signals in Hepa1c1c7 cells
    • Solhaug,A., Refsnes,M., Lag,M., Schwarze,P.E., Husoy,T. and Holme,J.A. (2004) Polycyclic aromatic hydrocarbons induce both apoptotic and anti-apoptotic signals in Hepa1c1c7 cells. Carcinogenesis, 25, 809-819.
    • (2004) Carcinogenesis , vol.25 , pp. 809-819
    • Solhaug, A.1    Refsnes, M.2    Lag, M.3    Schwarze, P.E.4    Husoy, T.5    Holme, J.A.6
  • 16
    • 0027094098 scopus 로고
    • Toxic equivalency factors (TEFs) for polycyclic aromatic hydrocarbons (PAHs)
    • Nisbet,I.C. and LaGoy,P.K. (1992) Toxic equivalency factors (TEFs) for polycyclic aromatic hydrocarbons (PAHs). Regul. Toxicol. Pharmacol., 16, 290-300.
    • (1992) Regul. Toxicol. Pharmacol , vol.16 , pp. 290-300
    • Nisbet, I.C.1    LaGoy, P.K.2
  • 17
    • 0031784429 scopus 로고    scopus 로고
    • Potency equivalency factors for some polycyclic aromatic hydrocarbons and polycyclic aromatic hydrocarbon derivatives
    • Collins,J.F., Brown,J.P., Alexeeff,G.V. and Salmon,A.G. (1998) Potency equivalency factors for some polycyclic aromatic hydrocarbons and polycyclic aromatic hydrocarbon derivatives. Regul. Toxicol. Pharmacol., 28, 45-54.
    • (1998) Regul. Toxicol. Pharmacol , vol.28 , pp. 45-54
    • Collins, J.F.1    Brown, J.P.2    Alexeeff, G.V.3    Salmon, A.G.4
  • 18
    • 2142825650 scopus 로고    scopus 로고
    • Identification of a gene expression profile that discriminates indirect-acting genotoxins from direct-acting genotoxins
    • Hu,T., Gibson,D.P., Carr,G.J., Torontali,S.M., Tiesman,J.P., Chaney,J.G. and Aardema,M.J. (2004) Identification of a gene expression profile that discriminates indirect-acting genotoxins from direct-acting genotoxins. Mutat. Res., 549, 5-27.
    • (2004) Mutat. Res , vol.549 , pp. 5-27
    • Hu, T.1    Gibson, D.P.2    Carr, G.J.3    Torontali, S.M.4    Tiesman, J.P.5    Chaney, J.G.6    Aardema, M.J.7
  • 20
    • 0032191460 scopus 로고    scopus 로고
    • Benzo(a)pyrene-induced alterations in growth-related gene expression and signaling in precision-cut adult rat liver and kidney slices
    • Parrish,A.R., Fisher,R., Bral,C.M., Burghardt,R.C., Gandolfi,A.J., Brendel,K. and Ramos,K.S. (1998) Benzo(a)pyrene-induced alterations in growth-related gene expression and signaling in precision-cut adult rat liver and kidney slices. Toxicol. Appl. Pharmacol., 152, 302-8.
    • (1998) Toxicol. Appl. Pharmacol , vol.152 , pp. 302-308
    • Parrish, A.R.1    Fisher, R.2    Bral, C.M.3    Burghardt, R.C.4    Gandolfi, A.J.5    Brendel, K.6    Ramos, K.S.7
  • 21
    • 0032973226 scopus 로고    scopus 로고
    • Structural and functional integrity of precision-cut liver slices in xenobiotic metabolism: A comparison of the dynamic organ and multiwell plate culture procedures
    • Hashemi,E., Dobrota,M., Till,C. and Ioannides,C. (1999) Structural and functional integrity of precision-cut liver slices in xenobiotic metabolism: a comparison of the dynamic organ and multiwell plate culture procedures. Xenobiotica, 29, 11-25.
    • (1999) Xenobiotica , vol.29 , pp. 11-25
    • Hashemi, E.1    Dobrota, M.2    Till, C.3    Ioannides, C.4
  • 23
    • 0037076272 scopus 로고    scopus 로고
    • Diagnosis of multiple cancer types by shrunken centroids of gene expression
    • Tibshirani,R., Hastie,T., Narasimhan,B. and Chu,G. (2002) Diagnosis of multiple cancer types by shrunken centroids of gene expression. Proc. Natl Acad. Sci. USA, 99, 6567-6572.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 6567-6572
    • Tibshirani, R.1    Hastie, T.2    Narasimhan, B.3    Chu, G.4
  • 24
    • 0037263812 scopus 로고    scopus 로고
    • MAPPFinder: Using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data
    • Doniger,S.W., Salomonis,N., Dahlquist,K.D., Vranizan,K., Lawlor,S.C. and Conklin,B.R. (2003) MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data. Genome Biol., 4, R7.
    • (2003) Genome Biol , vol.4
    • Doniger, S.W.1    Salomonis, N.2    Dahlquist, K.D.3    Vranizan, K.4    Lawlor, S.C.5    Conklin, B.R.6
  • 25
    • 0036578644 scopus 로고    scopus 로고
    • GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways
    • Dahlquist,K.D., Salomonis,N., Vranizan,K., Lawlor,S.C. and Conklin,B.R. (2002) GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways. Nat. Genet., 31, 19-20.
    • (2002) Nat. Genet , vol.31 , pp. 19-20
    • Dahlquist, K.D.1    Salomonis, N.2    Vranizan, K.3    Lawlor, S.C.4    Conklin, B.R.5
  • 26
    • 0022774562 scopus 로고
    • Nuclease P1-mediated enhancement of sensitivity of 32P-postlabeling test for structurally diverse DNA adducts
    • Reddy,M.V. and Randerath,K. (1986) Nuclease P1-mediated enhancement of sensitivity of 32P-postlabeling test for structurally diverse DNA adducts. Carcinogenesis, 7, 1543-1551.
    • (1986) Carcinogenesis , vol.7 , pp. 1543-1551
    • Reddy, M.V.1    Randerath, K.2
  • 28
    • 0032446353 scopus 로고    scopus 로고
    • Differential regulation of transcription: Repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins
    • Bardwell,L., Cook,J.G., Zhu-Shimoni,J.X., Voora,D. and Thorner,J. (1998) Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins. Proc. Natl Acad. Sci. USA, 95, 15400-15405.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 15400-15405
    • Bardwell, L.1    Cook, J.G.2    Zhu-Shimoni, J.X.3    Voora, D.4    Thorner, J.5
  • 29
    • 0032814943 scopus 로고    scopus 로고
    • cDNA cloning, expression and activity of a second human aflatoxin B1-metabolizing member of the aldo-keto reductase superfamily, AKR7A3
    • Knight,L.P., Primiano,T., Groopman,J.D., Kensler,T.W. and Sutter,T.R. (1999) cDNA cloning, expression and activity of a second human aflatoxin B1-metabolizing member of the aldo-keto reductase superfamily, AKR7A3. Carcinogenesis, 20, 1215-1223.
    • (1999) Carcinogenesis , vol.20 , pp. 1215-1223
    • Knight, L.P.1    Primiano, T.2    Groopman, J.D.3    Kensler, T.W.4    Sutter, T.R.5
  • 30
    • 0347364773 scopus 로고    scopus 로고
    • Phase I and II carcinogen metabolism gene expression in human lung tissue and tumors
    • Spivack,S.D., Hurteau,G.J., Fasco,M.J. and Kaminsky,L.S. (2003) Phase I and II carcinogen metabolism gene expression in human lung tissue and tumors. Clin Cancer Res., 9, 6002-6011.
    • (2003) Clin Cancer Res , vol.9 , pp. 6002-6011
    • Spivack, S.D.1    Hurteau, G.J.2    Fasco, M.J.3    Kaminsky, L.S.4
  • 31
    • 33644855945 scopus 로고    scopus 로고
    • Modulation of gene expression and DNA adduct formation in HepG2 cells by polycyclic aromatic hydrocarbons with different carcinogenic potencies
    • Staal,Y.C., van Herwijnen,M.H., van Schooten,F.J. and van Delft,J.H. (2006) Modulation of gene expression and DNA adduct formation in HepG2 cells by polycyclic aromatic hydrocarbons with different carcinogenic potencies. Carcinogenesis, 27, 646-655.
    • (2006) Carcinogenesis , vol.27 , pp. 646-655
    • Staal, Y.C.1    van Herwijnen, M.H.2    van Schooten, F.J.3    van Delft, J.H.4
  • 32
    • 0032481136 scopus 로고    scopus 로고
    • Critical role of both retinoid nuclear receptors and retinoid-X-receptors in mediating growth inhibition of ovarian cancer cells by all-trans retinoic acid
    • Wu,S., Zhang,D., Zhang,Z.P., Soprano,D.R. and Soprano,K.J. (1998) Critical role of both retinoid nuclear receptors and retinoid-X-receptors in mediating growth inhibition of ovarian cancer cells by all-trans retinoic acid. Oncogene, 17, 2839-2849.
    • (1998) Oncogene , vol.17 , pp. 2839-2849
    • Wu, S.1    Zhang, D.2    Zhang, Z.P.3    Soprano, D.R.4    Soprano, K.J.5
  • 33
    • 22144466232 scopus 로고    scopus 로고
    • Disruption of the TGF-beta pathway and modeling human cancer in mice
    • Letterio,J.J. (2005) Disruption of the TGF-beta pathway and modeling human cancer in mice. Mutat Res., 576, 120-131.
    • (2005) Mutat Res , vol.576 , pp. 120-131
    • Letterio, J.J.1
  • 34
    • 0023035487 scopus 로고
    • Respiratory patterns in human brain tumors
    • Lichtor,T. and Dohrmann,G.J. (1986) Respiratory patterns in human brain tumors. Neurosurgery, 19, 896-899.
    • (1986) Neurosurgery , vol.19 , pp. 896-899
    • Lichtor, T.1    Dohrmann, G.J.2
  • 35
    • 0029077985 scopus 로고
    • The significance of the cholesterol biosynthetic pathway in cell growth and (review)
    • Rao,K.N. (1995) The significance of the cholesterol biosynthetic pathway in cell growth and (review). Anticancer Res., 15, 309-314.
    • (1995) Anticancer Res , vol.15 , pp. 309-314
    • Rao, K.N.1
  • 36
    • 0030691794 scopus 로고    scopus 로고
    • Early bioenergetic changes in hepatocarcinogenesis: Preneoplastic phenotypes mimic responses to insulin and thyroid hormone
    • Bannasch,P., Klimek,F. and Mayer,D. (1997) Early bioenergetic changes in hepatocarcinogenesis: preneoplastic phenotypes mimic responses to insulin and thyroid hormone. J. Bioenerg. Biomembr., 29, 303-313.
    • (1997) J. Bioenerg. Biomembr , vol.29 , pp. 303-313
    • Bannasch, P.1    Klimek, F.2    Mayer, D.3
  • 37
    • 33645105462 scopus 로고    scopus 로고
    • Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of totalbody burden and clearance rate
    • Uno,S., Dalton,T.P., Dragin,N., Curran,C.P., Derkenne,S., Miller,M.L., Shertzer,H.G., Gonzalez,F.J. and Nebert,D.W. (2006) Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of totalbody burden and clearance rate. Mol. Pharmacol., 69, 1103-1114.
    • (2006) Mol. Pharmacol , vol.69 , pp. 1103-1114
    • Uno, S.1    Dalton, T.P.2    Dragin, N.3    Curran, C.P.4    Derkenne, S.5    Miller, M.L.6    Shertzer, H.G.7    Gonzalez, F.J.8    Nebert, D.W.9
  • 38
    • 23044461801 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p- dioxin (TCDD) alters the mRNA expression of critical genes associated with cholesterol metabolism, bile acid biosynthesis, and bile transport in rat liver: A microarray study
    • Fletcher,N., Wahlstrom,D., Lundberg,R., Nilsson,C.B., Nilsson,K.C., Stockling,K., Hellmold,H. and Hakansson,H. (2005) 2,3,7,8-Tetrachlorodibenzo-p- dioxin (TCDD) alters the mRNA expression of critical genes associated with cholesterol metabolism, bile acid biosynthesis, and bile transport in rat liver: a microarray study. Toxicol. Appl. Pharmacol., 207, 1-24.
    • (2005) Toxicol. Appl. Pharmacol , vol.207 , pp. 1-24
    • Fletcher, N.1    Wahlstrom, D.2    Lundberg, R.3    Nilsson, C.B.4    Nilsson, K.C.5    Stockling, K.6    Hellmold, H.7    Hakansson, H.8
  • 39
    • 20344376407 scopus 로고    scopus 로고
    • Moss,S.F. and Blaser,M.J. (2005) Mechanisms of disease: Inflammation and the origins of cancer. Nat. Clin. Pract. Oncol., 2, 90-97; and quiz 1 p. following 113.
    • Moss,S.F. and Blaser,M.J. (2005) Mechanisms of disease: Inflammation and the origins of cancer. Nat. Clin. Pract. Oncol., 2, 90-97; and quiz 1 p. following 113.
  • 40
    • 0036637148 scopus 로고    scopus 로고
    • Expression of inflammation related enzymes during experimental rat lung carcinogenesis
    • Li,H., Chen,F., Yu,L., Liu,M., Chen,H., Zhang,Y. and Liu,X. (2002) Expression of inflammation related enzymes during experimental rat lung carcinogenesis. Zhonghua Zhong Liu Za Zhi, 24, 316-319.
    • (2002) Zhonghua Zhong Liu Za Zhi , vol.24 , pp. 316-319
    • Li, H.1    Chen, F.2    Yu, L.3    Liu, M.4    Chen, H.5    Zhang, Y.6    Liu, X.7
  • 41
    • 0036778027 scopus 로고    scopus 로고
    • Dynamic changes of matrix metalloproteinases in rat liver during the development of diethylnitrosamine-induced hepatocarcinoma
    • Gao,Y., Zhang,Z., Jiang,Z.S., Fang,S.G., Sun,E.W., Wang,Y. and Chen,B.H. (2002) Dynamic changes of matrix metalloproteinases in rat liver during the development of diethylnitrosamine-induced hepatocarcinoma. Di Yi Jun Yi Da Xue Xue Bao, 22, 865-868.
    • (2002) Di Yi Jun Yi Da Xue Xue Bao , vol.22 , pp. 865-868
    • Gao, Y.1    Zhang, Z.2    Jiang, Z.S.3    Fang, S.G.4    Sun, E.W.5    Wang, Y.6    Chen, B.H.7


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