Synthesis of pyrophosphate-containing compounds that stimulate Vγ2Vδ2 T cells: Application to cancer immunotherapy

Medicinal Chemistry

Volumn 3, Issue 1, 2007, Pages 85-99

  Tanaka, Y ^a,b   Kobayashi, H ^c   Terasaki, T ^a   Toma, H ^c   Aruga, A ^c   Uchiyama, T ^c   Mizutani, K ^a   Mikami, B ^a   Morita, C T ^d   Minato, N ^a  

^a KYOTO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^d UNIVERSITY OF IOWA   (United States)

Author keywords

T cell; Cancer; Cytotoxicity; Immunotherapy; Pyrophosphomonoester; T cell receptor

Indexed keywords

2 METHYL 3 BUTENYL 1 PYROPHOSPHATE; BISPHOSPHONIC ACID DERIVATIVE; HUMAN SERUM ALBUMIN; ISOPRENOID PHOSPHATE; PYROPHOSPHORIC ACID DERIVATIVE; T LYMPHOCYTE RECEPTOR DELTA CHAIN; T LYMPHOCYTE RECEPTOR GAMMA CHAIN; UNCLASSIFIED DRUG;

ANTIGEN RECOGNITION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER IMMUNOTHERAPY; CANCER PATIENT; CONTROLLED STUDY; CYTOTOXICITY; DONOR; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIVER CARCINOMA; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANTIBODY SPECIFICITY; ANTIGENS, NEOPLASM; ANTINEOPLASTIC AGENTS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; CLONE CELLS; DIPHOSPHATES; DIPHOSPHONATES; FLOW CYTOMETRY; HUMANS; IMMUNOTHERAPY; INTERLEUKIN-2; JURKAT CELLS; MODELS, MOLECULAR; MONOCYTES; NEOPLASMS; T-LYMPHOCYTES;

EID: 33846073591     PISSN: 15734064     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340607779317544     Document Type: Article

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