Quantitative genetics of cortical bone mass in healthy 10-year-old children from the Fels Longitudinal Study

Bone

Volumn 40, Issue 2, 2007, Pages 464-470

  Duren, Dana L ^a   Sherwood, Richard J ^a   Choh, Audrey C ^a   Czerwinski, Stefan A ^a   Cameron Chumlea, Wm ^a   Lee, Miryoung ^a   Sun, Shumei S ^a   Demerath, Ellen W ^a   Siervogel, Roger M ^a   Towne, Bradford ^a  

^a WRIGHT STATE UNIVERSITY   (United States)

Author keywords

Bone size; Genetics; Maturation; Radiography

Indexed keywords

ARTICLE; BONE AGE; BONE DEVELOPMENT; BONE GROWTH; BONE MASS; BONE MATURATION; BONE RADIOGRAPHY; CORTICAL BONE; FEMALE; GENETIC CORRELATION; GENETIC REGULATION; GENETIC TRAIT; HERITABILITY; HUMAN; HUMAN EXPERIMENT; LIFESPAN; MALE; MAXIMUM LIKELIHOOD METHOD; METACARPAL BONE; NORMAL HUMAN; PEDIGREE; PREPUBERTY; QUANTITATIVE GENETICS; SCHOOL CHILD; THICKNESS; UNITED STATES; VARIANCE;

BONE DENSITY; BONE DEVELOPMENT; CHILD; FAMILY; FEMALE; HUMANS; INHERITANCE PATTERNS; LONGITUDINAL STUDIES; MALE; MULTIVARIATE ANALYSIS; PEDIGREE;

EID: 33846004170     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2006.09.015     Document Type: Article

References (66)

1. Akhter M.P., Iwaniec U.T., Covey M.A., Cullen D.M., Kimmel D.B., and Recker R.R. Genetic variations in bone density, histomorphometry, and strength in mice. Calcif. Tissue Int. 67 (2000) 337-344
2. Almasy L., and Blangero J. Multipoint quantitative-trait linkage analysis in general pedigrees. Am. J. Hum. Genet. 62 (1998) 1198-1211
3. Audi L., Garcia-Ramirez M., and Carrascosa A. Genetic determinants of bone mass. Horm. Res. 51 (1999) 105-123
4. Barnett E., and Nordin B.E.C. The radiological diagnosis of osteoporosis: a new approach. Clin. Radiol. 11 (1960) 166-174
5. Beamer W.G., Donahue L.R., Rosen C.J., and Baylink D.J. Genetic variability in adult bone density among inbred strains of mice. Bone 18 (1996) 397-403
6. Christian J.C., Yu P.L., Slemenda C.W., and Johnston Jr. C.C. Heritability of bone mass: a longitudinal study in aging male twins. Am. J. Hum. Genet. 44 (1989) 429-433
7. Clausson B., Lichtenstein P., and Cnattinigius S. Genetic influence on birthweight and gestational length determined by studies in offspring of twins. Br. J. Genet. 107 (2000) 375-381
8. Cohen Z., Kalichman L., Kobyliansky E., Malkin I., Almog E., and Livshits G. Cortical index and size of hand bones: segregation analysis and linkage with the 11q12-13 segment. Med. Sci. Monit. 9 (2003) MT13-MT20
9. Deng H.W., Livshits G., Yakovenko K., Xu F.H., Conway T., Davies K.M., et al. Evidence for a major gene for bone mineral density/content in human pedigrees identified via probands with extreme bone mineral density. Ann. Hum. Genet. 66 (2002) 61-74
10. Dequeker J. Quantitative radiology: radiogrammetry of cortical bone. Br. J. Radiol. 49 (1976) 912-920
11. Edwards A.W.F. Likelihood, expanded ed (1992), Johns Hopkins Univ. Press, Baltimore
12. Exton-Smith A.N., Millard P.H., Payne P.R., and Wheeler E.F. Method for measuring quantity of bone. Lancet 7631 (1969) 1153-1154
13. Ferrari S., Rizzoli R., Slosman D., and Bonjour J.P. Familial resemblance for bone mineral mass is expressed before puberty. J. Clin. Endocrinol. Metab. 83 (1998) 358-361
14. Fischbein S., and Nordqvist T. Profile comparisons of physical growth for monozygotic and dizygotic twin pairs. Ann. Hum. Biol. 5 (1978) 321-328
15. Garn S.M. The earlier gain and the later loss of cortical bone (1970), Bannerstone House, Springfield, IL
16. Garn S.M., Poznanski A.K., and Nagy J.M. Bone measurement in the differential diagnosis of osteopenia and osteoporosis. Radiology 100 (1971) 509-518
17. Garn S.M., Feutz E., Colbert C., and Wagner B. Comparison of cortical thickness and radiographic microdensitometry in the measurement of bone loss. Progress in development of methods in bone densitometry (1966), NASA, Washington, DC 65-77
18. Gueguen R., Jouanny P., Guillemin F., Kuntz C., Pourel J., and Siest G. Segregation analysis and variance components analysis of bone mineral density in healthy families. J. Bone Miner. Res. 10 (1995) 2017-2022
19. Havill L.M., Mahaney M.C., Cox L.A., Morin P.A., Joslyn G., and Rogers J. A quantitative trait locus for normal variation in forearm bone mineral density in pedigreed baboons maps to the ortholog of human chromosome 11q. J. Clin. Endocrinol. Metab. 90 (2005) 3638-3645
20. Havill L.M., Mahaney M.C., and Rogers J. Genotype-by-sex and environment-by-sex interactions influence variation in serum levels of bone-specific alkaline phosphatase in adult baboons (Papio hamadryas). Bone 35 (2004) 198-203
21. Heaney R.P., Abrams S., Dawson-Hughes B., Looker A., Marcus R., Matkovic V., et al. Peak bone mass. Osteoporos Int. 11 (2000) 985-1009
22. Henry Y.M., Fatayerji D., and Eastell R. Attainment of peak bone mass at the lumbar spine, femoral neck and radius in men and women: relative contributions of bone size and volumetric bone mineral density. Osteoporos Int. 15 (2004) 263-273
23. Hopper J.L., Green R.M., Nowson C.A., Young D., Sherwin A.J., Kaymakci B., et al. Genetic, common environment, and individual specific components of variance for bone mineral density in 10- to 26-year-old females: a twin study. Am. J. Epidemiol. 147 (1998) 17-29
24. Hui S.L., Zhou L., Evans R., Slemenda C.W., Peacock M., Weaver C.M., et al. Rates of growth and loss of bone mineral in the spine and femoral neck in white females. Osteoporos Int. 9 (1999) 200-205
25. Jones G., and Nguyen T.V. Associations between maternal peak bone mass and bone mass in prepubertal male and female children. J. Bone Miner. Res. 15 (2000) 1998-2004
26. Judex S., Garman R., Squire M., Donahue L.R., and Rubin C. Genetically based influences on the site-specific regulation of trabecular and cortical bone morphology. J. Bone Miner. Res. 19 (2004) 600-606
27. Kammerer C.M., Sparks M.L., and Rogers J. Effects of age, sex, and heredity on measures of bone mass in baboons (Papio hamadryas). J. Med. Primatol. 24 (1995) 236-242
28. Karasik D., Cupples L.A., Hannan M.T., and Kiel D.P. Age, gender, and body mass effects on quantitative trait loci for bone mineral density: the framingham study. Bone 33 (2003) 308-316
29. Karasik D., Ginsburg E., Livshits G., Pavlovsky O., and Kobyliansky E. Evidence of major gene control over cortical bone loss in humans. Genet. Epidemiol. 19 (2000) 410-421
30. Karasik D., Otremsky I., Barach I., Yakovenko K., Batsevich V., Pavlovsky O., et al. Comparative analysis of age prediction by markers of bone change in the hand assessed by roentgenography. Am. J. Hum. Biol. 11 (1999) 31-43
31. Klein R.F. Genetic regulation of bone mineral density in mice. J. Musculoskelet. Neuronal. Interact. 2 (2002) 232-236
32. Klein R.F., Shea M., Gunness M.E., Pelz G.B., Belknap J.K., and Orwoll E.S. Phenotypic characterization of mice bred for high and low peak bone mass. J. Bone Miner. Res. 16 (2001) 63-71
33. Koller D.L., White K.E., Liu G., Hui S.L., Conneally P.M., Johnston C.C., et al. Linkage of structure at the proximal femur to chromosomes 3, 7, 8, and 19. J. Bone Miner. Res. 18 (2003) 1057-1065
34. Lange K., and Boehnke M. Extensions to pedigree analysis: VI. Covariance components models for multivariate traits. Am. J. Med. Genet. 14 (1983) 513-524
35. Lee M., Czerwinski S.A., Choh A.C., Demerath E.W., Sun S.S., Chumlea W.C., et al. Unique and common genetic effects between bone mineral density and calcaneal quantitative ultrasound measures: the Fels Longitudinal Study. Osteoporos Int. 17 6 (2006) 865-871
36. Lee M., Czerwinski S.A., Choh A.C., Towne B., Demerath E.W., Chumlea W.C., et al. Heritability of calcaneal quantitative ultrasound measures in healthy adults from the Fels Longitudinal Study. Bone 35 (2004) 1157-1163
37. Lipkin E.W., Aumann C.A., and Newell-Morris L.L. Evidence for common controls over inheritance of bone quantity and body size from segregation analysis in a pedigreed colony of nonhuman primates. Bone 29 (2001) 249-257
38. Livshits G., Deng H.W., Nguyen T.V., Yakovenko K., Recker R.R., and Eisman J.A. Genetics of bone mineral density: evidence for a major pleiotropic effect from an intercontinental study. J. Bone Miner. Res. 19 (2004) 914-923
39. Livshits G., Karasik D., Otremsky I., and Kobyliansky E. Genes play an important role in bone aging. Am. J. Hum. Biol. 10 (1998) 421-438
40. Livshits G., Yakovenko K., and Kobyliansky E. Quantitative genetic study of radiographic hand bone size and geometry. Bone 32 (2003) 191-198
41. Lynch M., and Walsh B. Genetics and analysis of quantitative traits (1998), Sinauer Associates, Sunderland, MA
42. Malina R., Katzmarzyk P.T., and Beunen G.P. Relation between birth weight at term and growth rate, skeletal age, and cortical bone at 6-11 years. Am. J. Hum. Biol. 11 (1999) 505-511
43. Mitchell B.D., Kammerer C.M., Schneider J.L., Perez R., and Bauer R.L. Genetic and environmental determinants of bone mineral density in Mexican Americans: results from the San Antonio Family Osteoporosis Study. Bone 33 (2003) 839-846
44. Nguyen T.V., Maynard L.M., Towne B., Roche A.F., Wisemandle W., Li J., et al. Sex differences in bone mass acquisition during growth: the Fels Longitudinal Study. J. Clin. Densitom. 4 (2001) 147
45. Orwoll E.S., Belknap J.K., and Klein R.F. Gender specificity in the genetic determinants of peak bone mass. J. Bone Miner. Res. 16 (2001) 1962-1971
46. Plato C.C., Fox K.M., and Tobin J.D. Skeletal changes in human aging. In: Crews D.E., and Garruto R.M. (Eds). Biological anthropology and aging: perspectives on human variation over the life span (1994), Oxford Univ. Press, New York
47. Recker R.R., and Deng HW. Role of genetics in osteoporosis. Endocrine 17 (2002) 55-66
48. Report of a WHO study group 1994 Assessment of fracture risk and its application to screening for postmenopausal osteoporosis., 843 ed. World Health Organization, Geneva.
49. Roche A.F. Growth, maturation, and body composition: The Fels Longitudinal Study (1992), Cambridge Univ. Press, Cambridge
50. Roche A.F., Chumlea W.mC., and Thissen D. Assessing the skeletal maturity of the hand-wrist: FELS method (1988), Charles C. Thomas, Springfield
51. Rubin L.A., Patel M.S., and Cole D.E. Genetic determinants of bone mass acquisition and risk for osteoporosis. Drug Dev. Res. 49 (2000) 216-226
52. Shafer JR, Kammerer CM, Bruder J, Bauer RL, Mitchell BD. Five-year change in bone mineral density is heritable in Mexican Americans: The San Antonio Family Ostoporosis Study. ASBMR [serial online].
53. Sheng M.H., Baylink D.J., Beamer W.G., Donahue L.R., Rosen C.J., Lau K.H., et al. Histomorphometric studies show that bone formation and bone mineral apposition rates are greater in C3H/HeJ (high-density) than C57BL/6J (low-density) mice during growth. Bone 25 (1999) 421-429
54. Sherwood R.J., Duren D., Blangero J., and Towne B. Genetic architecture of the human skull during growth. Acta Med. Auxol. (2004) 98-99 [Abstracts]
55. Shimizu M., Higuchi K., Bennett B., Xia C., Tsuboyama T., Kasai S., et al. Identification of peak bone mass QTL in a spontaneously osteoporotic mouse strain. Mamm. Genome 10 (1999) 81-87
56. Slemenda C.W., Christian J.C., Williams C.J., Norton J.A., and Johnston Jr. C.C. Genetic determinants of bone mass in adult women: a reevaluation of the twin model and the potential importance of gene interaction on heritability estimates. J. Bone Miner. Res. 6 (1991) 561-567
57. Smith D.M., Nance W.E., Kang K.W., Christian J.C., and Johnston Jr. C.C. Genetic factors in determining bone mass. J. Clin. Invest. 52 (1973) 2800-2808
58. Smith Jr. R.W. Dietary and hormonal factors in bone loss. Fed. Proc. 26 (1967) 1737-1746
59. Smith Jr. R.W., and Frame B. Concurrent axial and appendicular osteoporosis: its relation to calcium consumption. N. Engl. J. Med. 273 (1965) 73
60. Specker B., Binkley T., and Fahrenwald N. Rural versus nonrural differences in BMC, volumetric BMD, and bone size: a population-based cross-sectional study. Bone 35 (2004) 1389-1398
61. Towne B., Guo S., Roche A., and Siervogel R. Genetic analysis of patterns of growth in infant recumbent length. Hum. Biol. 65 (1993) 977-989
62. Volkman S.K., Galecki A.T., Burke D.T., Paczas M.R., Moalli M.R., Miller R.A., et al. Quantitative trait loci for femoral size and shape in a genetically heterogeneous mouse population. J. Bone Miner. Res. 18 (2003) 1497-1505
63. Wilson R. Concordance in physical growth for monozygotic and dizygotic twins. Ann Hum Biol 3 (1976) 1-10
64. Wynne F., Drummond F.J., Daly M., Brown M., Shanahan F., Molloy M.G., et al. Suggestive linkage of 2p22-25 and 11q12-13 with low bone mineral density at the lumbar spine in the Irish population. Calcif. Tissue Int. 72 (2003) 651-658
65. Zhao G., Monier-Faugere M.C., Langub M.C., Geng Z., Nakayama T., Pike J.W., et al. Targeted overexpression of insulin-like growth factor I to osteoblasts of transgenic mice: increased trabecular bone volume without increased osteoblast proliferation. Endocrinology 141 (2000) 2674-2682
66. Zhao X., Zhang Z., Song Y., Zhang X., Zhang Y., Hu Y., et al. Transgenically ectopic expression of Bmp4 to the Msx1 mutant dental mesenchyme restores downstream gene expression but represses Shh and Bmp2 in the enamel knot of wild type tooth germ. Mech. Dev. 99 (2000) 29-38