Transgenically ectopic expression of Bmp4 to the Msx1 mutant dental mesenchyme restores downstream gene expression but represses Shh and Bmp2 in the enamel knot of wild type tooth germ

Mechanisms of Development

Volumn 99, Issue 1-2, 2000, Pages 29-38

  Zhao, Xiang ^a   Zhang, Zunyi ^a   Song, Yiqiang ^a   Zhang, Xiaoyun ^a   Zhang, Yanding ^a   Hu, Yuping ^a   Fromm, Sigurd H ^b   Chen, YiPing ^a  

^a Tulane University   (United States)

^b UNIVERSITY OF OSLO   (Norway)

Author keywords

Bmp4; Enamel knot; Msx1; Shh; Tooth; Transgenic mice

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4;

ANIMAL TISSUE; ARTICLE; ENAMEL; GENE EXPRESSION; GENE REPRESSION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TOOTH DEVELOPMENT; TRANSGENIC MOUSE;

ALLELES; ANIMALS; BONE AND BONES; BONE MORPHOGENETIC PROTEINS; BROMODEOXYURIDINE; CELL DIVISION; DENTAL ENAMEL; DOWN-REGULATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOTYPE; HEDGEHOG PROTEINS; HOMEODOMAIN PROTEINS; IN SITU HYBRIDIZATION; IN SITU NICK-END LABELING; MESODERM; MICE; MSX1 TRANSCRIPTION FACTOR; MUTATION; PHENOTYPE; PROMOTER REGIONS (GENETICS); PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS; TOOTH; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFORMING GROWTH FACTOR BETA; TRANSGENES;

EID: 0033745316     PISSN: 09254773     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0925-4773(00)00467-6     Document Type: Article

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