Phenotypic characterization of mice bred for high and low peak bone mass

Journal of Bone and Mineral Research

Volumn 16, Issue 1, 2001, Pages 63-71

  Klein, Robert F ^a   Shea, Marie ^b,c   Gunness, Michele E ^b,c   Pelz, Geoffrey B ^b   Belknap, John K ^b   Orwoll, Eric S ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c NONE   (United States)

Author keywords

Biomechanics; Bone mineral density; Genetics; Histomorphometry; Mouse; Osteoporosis

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOMECHANICS; BONE DENSITY; BONE MASS; BONE MINERAL; BONE STRENGTH; CHEMICAL ANALYSIS; DUAL ENERGY X RAY ABSORPTIOMETRY; GENETIC ANALYSIS; GENETIC RISK; HEREDITY; MORPHOMETRICS; MOUSE; NONHUMAN; OSSIFICATION; OSTEOPOROSIS; PHENOTYPE; PROGENY;

EID: 0035171446     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.2001.16.1.63     Document Type: Article

References (37)

1. Genetics of osteoporosis
2. On the rat model of human osteopenias and osteoporoses
3. Diagnostic tools and biologic markers: Animal models in the study of osteoporosis and oral bone loss
4. Available animal models of osteopenia-small and large
5. Taking stock of complex trait genetics in mice
6. A miracle enough: The power of mice
7. Age and bone mass as predictors of fracture in a prospective study
8. Appendicular bone density and age predict hip fracture in women
9. Genetic lineage, bone mass, and physical activity
10. Genetic variability in adult bone density among inbred strains of mice
11. Identification of peak bone mass QTL in a spontaneously osteoporotic mouse strain
12. Quantitative trait loci for bone density in C57BL/6J and CAST/EiJ inbred mice
13. Localization of genes contributing to failure load and related phenotypes in HcB/Dem recombinant congenic mice
14. Genetic mapping of loci conferring osteopenia using closely-related mouse strains
15. Quantitative trait loci affecting peak bone mineral density in mice
16. Short-term selective breeding as a tool for QTL mapping: Ethanol preference drinking in mice
17. Bone histomorphometric and biomechanical abnormalities in mice homozygous for deletion of the dopamine transporter gene
18. Bone histomorphometry: Standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee
19. Basic biomechanical measurements of bone: A tutorial
20. Heredity
21. Factors associated with appendicular bone mass in older women: The Study of Osteoporotic Fractures Research Group
22. Axial bone mass in older women
23. Genetic regulation of cortical and trabecular bone strength and microstructure in inbred strains of mice
24. Growing C57B1/6 mice increase whole bone mechanical properties by increasing geometric and material properties
25. Histomorphometric studies show that bone formation and bone mineral apposition rates are greater in C3H/HeJ (high-density) than C57BL/6J (low-density) mice during growth
26. The effects of race and body habitus on bone mineral density of the radius, hip, and spine in premenopausal women
27. Demonstration that bone mineral density of the lumbar spine, trochanter, and femoral neck is higher in black than in white young men
28. Racial differences in bone density between young adult black and white subjects persist after adjustment for anthropometric, lifestyle, and biochemical differences
29. Epidemiology of osteoporosis and osteoporotic fractures
30. Racial differences in hip axis lengths might explain racial differences in rates of hip fracture. Study of Osteoporotic Fractures Research Group
31. Bone mineral content in black and white children 1 to 6 years of age. Early appearance of race and sex differences
32. Demonstration that bone mass is greater in black than in white children
33. Effect of ethnicity and age or menopause on the structure and geometry of iliac bone
34. Effects of ethnicity and age or menopause on the remodeling and turnover of iliac bone: Implications for mechanisms of bone loss
35. The mechanostat: A proposed pathogenic mechanism of osteoporoses and the bone mass effects of mechanical and nonmechanical agents
36. Perspectives: Some roles of mechanical usage, muscle strength, and the mechanostat in skeletal physiology, disease, and research
37. Bone mass, the mechanostat, and ethnic differences