New knowledge regarding glucose-6 phosphatase gene and protein and their roles in the regulation of glucose metabolism

European Journal of Endocrinology

Volumn 136, Issue 2, 1997, Pages 137-145

  Mithieux, Gilles ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE 6 PHOSPHATASE;

GLUCOSE METABOLISM; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MOLECULAR BIOLOGY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; REVIEW;

EID: 0031051338     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1360137     Document Type: Review

References (66)

1. Ashmore J & Weber G. The role of hepatic glucose-6 phosphatase in the regulation of carbohydrate metabolism. Vitamins and Hormones 1959 17 91-132.
2. Nordlie RC. Glucose-6 phosphatase phosphotransferase: roles and regulation in relation to gluconeogenesis. In Gluconeogenesis: its Regulation in Mammalian Species, pp 53-152. Eds RW Hanson & MA Mehlman. New York: John Wiley & Sons, 1976.
3. Wirthensohn G & Gruder WG. Renal substrate metabolism. Physiological Reviews 1986 66 469-497.
4. Schulze HU, Nolte B & Kannler R. Evidence for changes in the conformational status of rat liver microsomal glucose-6 phosphate: phosphohydrolase during detergent-dependent membrane modification. Journal of Biological Chemistry 1986 261 16571-16578.
5. Arion WJ, Wallin BK, Lange AJ & Ballas LM. On the involvement of a glucose-6 phosphate transport system in the function of microsomal glucose-6 phosphatase. Molecular and Cellular Biochemistry 1975 6 75-83.
6. Newgard CB, Foster DW & McGarry JD. Evidence for suppression of hepatic glucose-6 phosphatase with carbohydrate feeding. Diabetes 1984 33 192-195.
7. Shelly LL, Lei KJ, Pan CJ, Sakata SF, Ruppert S, Schutz G et al. Isolation of the gene for murine glucose-6 phosphatase, the enzyme deficient in glycogen storage disease type 1a. Journal of Biological Chemistry 1993 268 21482-21485.
8. Glueckson-Waelsch S. Genetic control of morphogenetic and biochemical differentiation: lethal albino deletions in the mouse. Cell 1979 16 225-237.
9. Ruppert S, Boshart M, Bosch FX, Schmid W, Keith Fournier RE & Schütz G. Two genetically defined trans-acting loci coordinately regulate overlapping sets of liver-specific genes. Cell 1990 61 895-904.
10. Countaway JL, Waddell ID, Burchell A & Arion WJ. The phosphohydrolase component of the hepatic microsomal glucose-6 phosphatase system is a 36.5 kilodalton polypeptide. Journal of Biological Chemistry 1986 263 2672-2678.
11. 32P-glucose-6 phosphate. Journal of Biochemistry 1995 117 908-914.
12. Lei KJ, Shelly LL, Pan CJ, Sidbury JB & Chou JY. Mutations in the glucose-6 phosphatase gene that cause glycogen storage disease type 1a. Science 1993 262 580-583.
13. Lange AJ, Argaud D, El-Maghrabi MR, Pan W, Maitra SR & Pilkis SJ. Isolation of a cDNA for the catalytic subunit of rat liver glucose-6 phosphatase: regulation of gene expression in FAO hepatoma cells by insulin, dexamethasone and cAMP. Biochemical and Biophysical Research Communications 1994 201 302-309.
14. Haber BA, Chin S, Chuang E, Buikhuisen W, Naji A & Taub R. High levels of glucose-6 phosphatase gene and protein expression reflect an adaptative response in proliferating liver and diabetes. Journal of Clinical Investigation 1995 95 832-841.
15. Mithieux G, Vidal H, Zitoun C, Bruni N, Daniele N & Minassian C. Glucose-6 phosphatase mRNA and activity are increased to the same extent in kidney and liver of diabetic rats. Diabetes 1996 45 891-896.
16. Singh J, Nordlie RC & forgenson RA. Vanadate: a potent inhibitor of multi-functional glucose-6 phosphatase. Biochimica et Biophysica Acta 1981 678 477-482.
17. Burchell A. Molecular pathology of glucose-6 phosphatase. FASEB Journal 1990 4 2978-2988.
18. Lei KJ, Pan CJ, Shelly LL, Liu JL & Chou JY. Identification of mutations in the gene for glucose-6 phosphatase, the enzyme deficient in glycogen storage disease type 1a. Journal of Clinical Investigation 1994 93 1994-1999.
19. Lei KJ, Shelly LL, Lin B, Sidbury JB, Chen YT, Nordlie RC & Chou JY. Mutations in the glucose-6 phosphatase gene are associated with glycogen storage disease types 1a and 1aSP but not 1b and 1c. Journal of Clinical Investigation 1995 95 234-240.
20. Kajihara S, Matsuhashi S, Yamamoto K, Kido K, Tsuji K, Tanae A, Fujiyama S, Itoh T, Tanigawa K, Uchida M, Setoguchi Y, Motomura M, Mizuta T & Sakai T. Exon redefinition by a point mutation within exon 5 of the glucose-6 phosphatase gene is the major cause of glycogen storage disease type 1a in Japan. American Journal of Human Genetics 1995 57 549-555.
21. Hwu WL, Chuang SC, Tsai LP, Chang MH, Chuang SM & Wang TR. Glucose-6 phosphatase gene G327A mutation is common in Chinese patients with glycogen storage disease type 1a. Human Molecular Genetics 1995 4 1095-1096.
22. Lei KJ, Chen YT, Chen H, Wong LJC, Liu JL, McConkie-Rosell A, Van Hove JLK, Ou HCY, Yeh NJ, Pan LY & Yang Chou J. Genetic basis of glycogen storage disease type 1a: prevalent mutations in the glucose-6 phosphatase locus. American Journal of Human Genetics 1995 57 766-771.
23. Chevalier-Porst F, Bozon D, Bonardot AM, Bruni N, Mithieux G, Mathieu M & Maire I. Mutation analysis in 24 French patients with glycogen storage disease type 1a. Journal of Medical Genetics 1996 33 358-360.
24. Arion WJ, Lange AJ & Ballas AM. Quantitative aspects of relationship between glucose-6 phosphate transport and hydrolysis for microsomal glucose-6 phosphatase transport system. Journal of Biological Chemistry 1976 251 6784-6790.
25. Burchell A, Allan BB & Hume R. Glucose-6 phosphatase proteins of the endoplasmic reticulum. Molecular Membrane Biology 1994 11 221-227.
26. Nordlie RC, Sukalski KA, Munoz JM & Baldwin JJ. Type 1c, a novel glycogenosis. Underlying mechanism. Journal of Biological Chemistry 1983 258 9739-9744.
27. Nordlie RC, Scott HM, Waddell ID, Hume R & Burchell A. Analysis of human hepatic microsomal glucose-6 phosphatase in conditions where the T2 pyrophosphate/phosphate transport protein is absent. Biochemical Journal 1992 281 859-863.
28. Burchell A & Waddell ID. Diagnosis of a novel glycogen storage disease: type 1aSP. Journal of Inherited Metabolic Disease 1990 13 247-249.
29. Pears J, Jung RT, Browning MCK, Taylor R & Burchell A. Reactive hypoglycemia in association with disordered islet function and abnormal hepatic glucose-6 phosphatase activity: response to diazoxide. Diabetic Medicine 1991 8 268-271.
30. Burchell A & Gibb L. Diagnosis of type 1b and 1c glycogen storage disease. Journal of Inherited Metabolic Disease 1991 14 305-307.
31. Mithieux G & Zitoun C. Mechanisms by which fatty acyl-CoA esters inhibit or activate glucose-6 phosphatase in intact and detergent-treated rat liver microsomes. European Journal of Biochemistry 1996 235 799-803.
32. Berteloot A, Vidai H & van de Werve G. Rapid kinetics of liver microsomal glucose-6 phosphatase. Evidence for tight coupling between glucose-6 phosphate transport and phosphohydrolase activity. Journal of Biological Chemistry 1991 266 5497-5507.
33. Ajzannay A & Mithieux G. Glucose-6 phosphate and mannose-6 phosphate are equally and more actively hydrolyzed by glucose-6 phosphatase during hysteretic transition within intact microsomal membrane than after detergent-treatment. Archives of Biochemistry and Biophysics 1996 326 238-242.
34. St-Denis JF, Annabi B, Khoury H & van de Werve G, Histone II-A stimulates glucose-6 phosphatase and reveals mannose-6 phosphatase activities without permeabilization of liver microsomes. Biochemical Journal 1995 310 221-224.
35. Berteloot A, St-Denis JF & van de Werve G. Evidence for a membrane exchangeable glucose pool in the functioning of rat liver glucose-6 phosphatase. Journal of Biological Chemistry 1995 270 21098-21102.
36. Ajzannay A, Minassian C, Riou JP & Mithieux G. Glucose-6 phosphate phosphohydrolase of detergent-treated liver microsomal membranes exhibits a specific kinetic behaviour towards glucose-6 phosphate. European Journal of Biochemistry 1993 212 335-338.
37. Ajzannay A, Minassian C, Riou JP & Mithieux G. Glucose-6 phosphatase specificity after membrane solubilization by detergent-treatment. Journal of Biochemistry 1994 116 1336-1340.
38. Ness GC, Sukalski KA, Sample CE, Pendleton LC, McCreery MJ & Nordlie RC. Radiation inactivation analysis of rat liver microsomal glucose-6 phosphatase. Journal of Biological Chemistry 1989 264 7111-7114.
39. Collipp PJ, Carsten A, Chen SY, Thomas J & Maddaiah VT. Molecular weight of microsomal glucose-6 phosphatase of rat and human liver. Biochemical Medicine 1974 10 312-319.
40. Howell RR. The glycogen storage disease. In The Metabolic Basis of Inherited Disease, pp 149-173. Eds JB Stanbury, JB Wyngaarden & DS Fredrickson. New York: McGraw Hill, 1972.
41. Mithieux G, Bordet JC, Minassian C, Ajzannay A, Mercier I & Riou JP. Characteristics and specificity of the inhibition of liver glucose-6 phosphatase by arachidonic acid. Lesser inhibitability of the enzyme of diabetic rats. European Journal of Biochemistry 1993 213 461-466.
42. Waddell ID & Burchell A. The microsomal glucose-6 phosphatase of pancreatic islets. Biochemical Journal 1988 255 471-476.
43. Matschinsky FM. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm. Diabetes 1996 45 223-241.
44. Minassian C & Mithieux G. Differential time-course of liver and kidney glucose-6 phosphatase activity during fasting in rats. Comparative Biochemistry and Physiology 1994 109B 99-104.
45. Minassian C, Zitoun C & Mithieux G. Differential time course of liver and kidney glucose-6 phosphatase activity during fasting in rats correlates with differential time course of messenger RNA level. Molecular and Cellular Biochemistry 1996 155 37-41.
46. Minassian C, Ajzannay A, Riou JP & Mithieux G. Investigation of the mechanism of glycogen rebound in the liver of 72-h-fasted rats. Journal of Biological Chemistry 1994 265 16585-16588.
47. Owen DE, Felig P, Morgan AP, Wahren J & Cahill GF. Liver and kidney metabolism during prolonged starvation. Journal of Clinical Investigation 1969 48 574-583.
48. Pontremoli S, Melloni E, Salamino F, De Flora A & Horecker BL. Changes in activity and molecular properties of fructose-1,6-bisphosphatase during fasting and refeeding. Proceedings of the National Academy of Sciences of the USA 1974 71 1776-1779.
49. Liu Z, Barrett EJ, Dalkin AC, Zwart AD & Chou JY. Effect of acute diabetes on rat hepatic glucose-6 phosphatase activity and its messenger RNA level. Biochemical and Biophysical Research Communications 1994 205 680-686.
50. Massillon D, Barzilai N, Chen W, Hu M & Rossetti L. Glucose regulates in vivo glucose-6 phosphatase gene expression in the liver of diabetic rats. Journal of Biological Chemistry 1996 271 9871-9874.
51. Lavoie L, Dimitrakoudis D, Maretet A, Annabi B, Klip A, Vranic M & van de Werve G. Opposite effects of hyperglycemia and insulin deficiency on liver glycogen synthase phosphatase activity in the diabetic rat. Diabetes 1993 42 363-366.
52. Alleyne GAO & Scullard GH. Renal metabolic response to acid-base changes. I. Enzymatic control of ammoniagenesis in the rat. Journal of Clinical Investigation 1969 48 364-370.
53. Adrogue HJ, Cornstock JP, Pena J, Hartley C, Entman M & Rashad MN. Large renal production (RGP) in conscious diabetic dogs without acidosis. Diabetes 1990 39 (Suppl 1) 24A.
54. Kida K, Nakajo S, Kamiya F, Toyama Y, Nishio T & Nakagawa H. Renal glucose release in vivo and its contribution to blood glucose in rats. Journal of Clinical Investigation 1978 62 721-726.
55. Maitra SR, Pan W, Lange AJ, El-Maghrabi MR, Abumrad NN & Pilkis SJ. Glucose-6-phosphatase gene expression and activity are modulated in hemorrhagic shock: evidence for a new heat-sensitive activator. Biochemical and Biophysical Research Communications 1994 204 716-724.
56. Christ B, Probst I & Jungermann K. Antagonistic regulation of the glucose/glucose-6 phosphate cycle by insulin and glucagon in cultured hepatocytes. Biochemical Journal 1986 238 185-191.
57. Bode AM, Foster JD & Nordlie RC. Glyconeogenesis from L-proline involves metabolic inhibition of the glucose-6 phosphatase system. Journal of Biological Chemistry 1992 267 2860-2863.
58. Gardner LB, Liu Z & Barrett EJ. The role of glucose-6 phosphatase in the action of insulin on hepatic glucose production in the rat. Diabetes 1993 42 1614-1620.
59. Minassian C, Daniele N, Bordet JC, Zitoun C & Mithieux G. Liver glucose-6 phosphatase activity is inhibited by refeeding in rats. Journal of Nutrition 1995 125 2727-2732.
60. Mithieux G, Vega F & Riou JP. The liver glucose-6 phosphatase of intact microsomes is inhibited and displays sigmoid kinetics in the presence of α-ketoglutarate-magnesium and oxaloacetate-magnesium chelates. Journal of Biological Chemistry 1990 265 20364-20368.
61. ++ on the activity of liver microsomal glucose-6 phosphatase. Journal of Biological Chemistry 1990 265 7257-7259.
62. Mithieux G. Role of glucokinase and glucose-6 phosphatase in the nutritional regulation of endogenous glucose production. Reproduction Nutrition Development 1996 36 357-362.
63. Massillon D, Angelov I, Barzilai N, Chen W, Hu M & Rossetti L. The gluconeogenic amino acid proline (PRO) is a potent inhibitor of hepatic glucose-6 phosphatase (Glc6Pase) flux in vivo. Diabetes 1996 45 (Suppl 2) 35A.
64. Van Schaftingen E. Short-term regulation of glucokinase. Diabetologia 1994 37 (Suppl 2) S43-S47.
65. Robbins BL, Foster JD & Nordlie RC. Metabolic intermediates as potential regulators of glucose-6 phosphatase. Life Sciences 1991 48 1075-1081.
66. Schmoll D, Allan BA & Burchell A. Cloning and sequencing of the 5′ region of the human glucose-6 phosphatase gene: transcriptional regulation by cAMP, insulin and glucocorticoids in H4IIE hepatoma cells. FEBS Letters 1996 383 63-66.