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Volumn 143, Issue 2, 1997, Pages 315-323

Role of CYP3A in ethanol-mediated increases in acetaminophen hepatotoxicity

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CYTOCHROME P450 ISOENZYME; PARACETAMOL; TROLEANDOMYCIN;

EID: 0030896138     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1996.8081     Document Type: Article
Times cited : (56)

References (48)
  • 1
    • 0021280337 scopus 로고
    • Interaction of acute ethanol administration with APAP metabolism and toxicity in rats fed alcohol chronically
    • Altomare E., Leo M. A., Sato C., Lieber C. S., Larrey D. Interaction of acute ethanol administration with APAP metabolism and toxicity in rats fed alcohol chronically. Alcoholism. 8:1984;405-408.
    • (1984) Alcoholism , vol.8 , pp. 405-408
    • Altomare, E.1    Leo, M.A.2    Sato, C.3    Lieber, C.S.4    Larrey, D.5
  • 2
    • 0021356015 scopus 로고
    • The effect of alcohol on the toxicity of acetaminophen in mice
    • Banda P. W., Quart B. D. The effect of alcohol on the toxicity of acetaminophen in mice. Res. Commun. Chem. Pathol. Pharmacol. 43:1984;127-138.
    • (1984) Res. Commun. Chem. Pathol. Pharmacol. , vol.43 , pp. 127-138
    • Banda, P.W.1    Quart, B.D.2
  • 4
    • 0029590145 scopus 로고
    • Fasting for less than 24 h induces cytochrome P450 2E1 and 2B1/2 activities in rats
    • Brown B., Allis J., Simmons J., House D. Fasting for less than 24 h induces cytochrome P450 2E1 and 2B1/2 activities in rats. Toxicol. Lett. 81:1995;39-44.
    • (1995) Toxicol. Lett. , vol.81 , pp. 39-44
    • Brown, B.1    Allis, J.2    Simmons, J.3    House, D.4
  • 5
    • 0025300029 scopus 로고
    • Isoniazid potentiation of acetaminophen hepatotoxicity in the rat and 4-methylpyrazole inhibition of it
    • Burk R. F., Hill K. E., Hunt R. W., Martin A. E. Isoniazid potentiation of acetaminophen hepatotoxicity in the rat and 4-methylpyrazole inhibition of it. Res. Commun. Chem. Pathol. Pharm. 69:1990;115-118.
    • (1990) Res. Commun. Chem. Pathol. Pharm. , vol.69 , pp. 115-118
    • Burk, R.F.1    Hill, K.E.2    Hunt, R.W.3    Martin, A.E.4
  • 6
    • 0027930952 scopus 로고
    • Ethanol increases the content and activity of human cytochrome P4502E1 in a transduced HepG2 cell line
    • Carroccio A., Wu D., Cederbaum A. Ethanol increases the content and activity of human cytochrome P4502E1 in a transduced HepG2 cell line. Biochem. Biophys. Res. Commun. 203:1994;727-733.
    • (1994) Biochem. Biophys. Res. Commun. , vol.203 , pp. 727-733
    • Carroccio, A.1    Wu, D.2    Cederbaum, A.3
  • 7
    • 0028174881 scopus 로고
    • Evaluation of triacetyloleandomycin, α-naphthoflavone and diethyldithiocarbamate as selective chemical probes for inhibition of human cytochromes P450
    • Chang T. K., Gonzalez F. J., Waxman D. J. Evaluation of triacetyloleandomycin, α-naphthoflavone and diethyldithiocarbamate as selective chemical probes for inhibition of human cytochromes P450. Arch. Biochem. Biophys. 311:1994;437-442.
    • (1994) Arch. Biochem. Biophys. , vol.311 , pp. 437-442
    • Chang, T.K.1    Gonzalez, F.J.2    Waxman, D.J.3
  • 8
    • 0026817134 scopus 로고
    • Effects of ethanol, dexamethasone and RU 486 on expression of cytochromes P450 2B, 2E, 3A and glutathione transferase pi in a rat hepatoma cell line (Fao)
    • de Waziers I., Bouguet J., Beaune P. H., Gonzalez F. J., Ketterer B., Barouki R. Effects of ethanol, dexamethasone and RU 486 on expression of cytochromes P450 2B, 2E, 3A and glutathione transferase pi in a rat hepatoma cell line (Fao). Pharmacogenetics. 2:1992;12-18.
    • (1992) Pharmacogenetics , vol.2 , pp. 12-18
    • De Waziers, I.1    Bouguet, J.2    Beaune, P.H.3    Gonzalez, F.J.4    Ketterer, B.5    Barouki, R.6
  • 9
    • 0023947818 scopus 로고
    • Cytochrome P-450 isozyme selectivity in the oxidation of acetaminophen
    • Harvison P., Guengerich F., Rashed M., Nelson S. Cytochrome P-450 isozyme selectivity in the oxidation of acetaminophen. Chem. Res. Toxicol. 1:1988;47-52.
    • (1988) Chem. Res. Toxicol. , vol.1 , pp. 47-52
    • Harvison, P.1    Guengerich, F.2    Rashed, M.3    Nelson, S.4
  • 10
    • 0029417160 scopus 로고
    • Urinary 6β-hydroxycortisol excretion in patients with alcoholic liver disease
    • Hoshino U., Kawasaki H. Urinary 6β-hydroxycortisol excretion in patients with alcoholic liver disease. Res. Commun. Alcohol. Sub. Abuse. 16:1995;116-124.
    • (1995) Res. Commun. Alcohol. Sub. Abuse , vol.16 , pp. 116-124
    • Hoshino, U.1    Kawasaki, H.2
  • 11
    • 0027182788 scopus 로고
    • Interaction of caffeine with acetaminophen
    • Jaw S., Jeffery E. Interaction of caffeine with acetaminophen. Biochem. Pharmacol. 46:1993;493-501.
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 493-501
    • Jaw, S.1    Jeffery, E.2
  • 13
    • 0020458459 scopus 로고
    • Purification and characterization of a unique isozyme of cytochrome P450 from liver microsomes of ethanol-treated rabbits
    • Koop D., Morgan E., Tarr G., Coon M. Purification and characterization of a unique isozyme of cytochrome P450 from liver microsomes of ethanol-treated rabbits. J. Biol. Chem. 257:1982;8472-8480.
    • (1982) J. Biol. Chem. , vol.257 , pp. 8472-8480
    • Koop, D.1    Morgan, E.2    Tarr, G.3    Coon, M.4
  • 16
    • 0031014979 scopus 로고    scopus 로고
    • Protection of ethanol-mediated increases in acetaminophen hepatotoxicity by triacetyloleandomycin, a specific inhibitor of CYP3A
    • Kostrubsky V., Szakacs J., Jeffery E., Wood S., Bement W., Wrighton S., Sinclair P., Sinclair J. Protection of ethanol-mediated increases in acetaminophen hepatotoxicity by triacetyloleandomycin, a specific inhibitor of CYP3A. Ann. Clin. Lab. Sci. 27:1997;57-62.
    • (1997) Ann. Clin. Lab. Sci. , vol.27 , pp. 57-62
    • Kostrubsky, V.1    Szakacs, J.2    Jeffery, E.3    Wood, S.4    Bement, W.5    Wrighton, S.6    Sinclair, P.7    Sinclair, J.8
  • 17
    • 0022001457 scopus 로고
    • Effect of ethanol on drug and metabolite pharmacokinetics
    • Lane E., Guthrie S., Linnoila M. Effect of ethanol on drug and metabolite pharmacokinetics. Clin. Pharmacokinet. 10:1985;228-247.
    • (1985) Clin. Pharmacokinet. , vol.10 , pp. 228-247
    • Lane, E.1    Guthrie, S.2    Linnoila, M.3
  • 19
    • 0027265259 scopus 로고
    • Biochemical factors in alcoholic liver disease
    • Lieber C. S. Biochemical factors in alcoholic liver disease. Semin. Liver. Dis. 13:1993;136-153.
    • (1993) Semin. Liver. Dis. , vol.13 , pp. 136-153
    • Lieber, C.S.1
  • 20
    • 0027447395 scopus 로고
    • Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers
    • Lindstrom T. D., Hanssen B. R., Wrighton S. A. Cytochrome P-450 complex formation by dirithromycin and other macrolides in rat and human livers. Antimicrob. Agents Chemother. 37:1993;265-269.
    • (1993) Antimicrob. Agents Chemother. , vol.37 , pp. 265-269
    • Lindstrom, T.D.1    Hanssen, B.R.2    Wrighton, S.A.3
  • 21
    • 84978596368 scopus 로고
    • The identification of distilled alcoholic beverages
    • Lisle D., Richards C., Wardleworth D. The identification of distilled alcoholic beverages. J. Inst. Brew. 84:1978;93-96.
    • (1978) J. Inst. Brew. , vol.84 , pp. 93-96
    • Lisle, D.1    Richards, C.2    Wardleworth, D.3
  • 23
    • 0026636286 scopus 로고
    • Effect of pregnenolone-16 α-carbonitrile and dexamethasone on acetaminophen-induced hepatotoxicity in mice
    • Madhu C., Maziasz T., Klaassen C. Effect of pregnenolone-16 α-carbonitrile and dexamethasone on acetaminophen-induced hepatotoxicity in mice. Toxicol. Appl. Pharmacol. 115:1993;191-198.
    • (1993) Toxicol. Appl. Pharmacol. , vol.115 , pp. 191-198
    • Madhu, C.1    Maziasz, T.2    Klaassen, C.3
  • 24
    • 0020633304 scopus 로고
    • Comparison of six rabbit liver cytochrome P-450 isozymes in formation of a reactive metabolite of acetaminophen
    • Morgan E., Koop D., Coon M. Comparison of six rabbit liver cytochrome P-450 isozymes in formation of a reactive metabolite of acetaminophen. Biochem. Biophys. Res. Commun. 12:1983;8-13.
    • (1983) Biochem. Biophys. Res. Commun. , vol.12 , pp. 8-13
    • Morgan, E.1    Koop, D.2    Coon, M.3
  • 25
    • 0025694879 scopus 로고
    • Molecular mechanisms of the hepatotoxicity caused by acetaminophen
    • Nelson S. D. Molecular mechanisms of the hepatotoxicity caused by acetaminophen. Semin. Liver Dis. 10:1990;267-278.
    • (1990) Semin. Liver Dis. , vol.10 , pp. 267-278
    • Nelson, S.D.1
  • 26
    • 0028858960 scopus 로고
    • Cytochrome P450 inhibitors: Evaluation of specificities in thein vitro
    • Newton D. J., Wang R. W., Lu A. Y. H. Cytochrome P450 inhibitors: Evaluation of specificities in thein vitro. Drug. Metab. Dispos. 23:1995;154-158.
    • (1995) Drug. Metab. Dispos. , vol.23 , pp. 154-158
    • Newton, D.J.1    Wang, R.W.2    Lu, A.Y.H.3
  • 27
    • 0027304762 scopus 로고
    • Cytochrome P450 enzymes involved in acetaminophen activation by rat and liver human microsomes and their kinetics
    • Patten C. J., Thomas P. E., Guy R. L., Lee M., Gonzalez F. J., Guengerich P. F., Yang C. S. Cytochrome P450 enzymes involved in acetaminophen activation by rat and liver human microsomes and their kinetics. Chem. Res. Toxicol. 6:1993;511-518.
    • (1993) Chem. Res. Toxicol. , vol.6 , pp. 511-518
    • Patten, C.J.1    Thomas, P.E.2    Guy, R.L.3    Lee, M.4    Gonzalez, F.J.5    Guengerich, P.F.6    Yang, C.S.7
  • 29
    • 0024401849 scopus 로고
    • Acetaminophen activation by human liver cytochromes P450IIE and P450IA2
    • Raucy J., Lasker J., Lieber C., Black M. Acetaminophen activation by human liver cytochromes P450IIE and P450IA2. Arch. Biochem. Biophys. 271:1981;270-283.
    • (1981) Arch. Biochem. Biophys. , vol.271 , pp. 270-283
    • Raucy, J.1    Lasker, J.2    Lieber, C.3    Black, M.4
  • 30
    • 0023252379 scopus 로고
    • Identification of a human liver cytochrome P-450 exhibiting catalytic and immunochemical similarities to cytochrome P-450 3a of rabbit liver
    • Raucy J., Fernandes P., Black M., Yang S., Koop D. Identification of a human liver cytochrome P-450 exhibiting catalytic and immunochemical similarities to cytochrome P-450 3a of rabbit liver. Biochem. Pharmacol. 36:1987;2921-2926.
    • (1987) Biochem. Pharmacol. , vol.36 , pp. 2921-2926
    • Raucy, J.1    Fernandes, P.2    Black, M.3    Yang, S.4    Koop, D.5
  • 32
    • 0027257201 scopus 로고
    • Female rats release more corticosterone than males in response to alcohol: Influence of circulating sex steroids and possible consequences for blood alcohol levels. (1993)
    • Rivier C. Female rats release more corticosterone than males in response to alcohol: Influence of circulating sex steroids and possible consequences for blood alcohol levels. (1993). Alcohol Clin. Exp. Res. 17:1993;854-859.
    • (1993) Alcohol Clin. Exp. Res. , vol.17 , pp. 854-859
    • Rivier, C.1
  • 33
    • 0028641564 scopus 로고
    • Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: Evidence that CYP2E1 possesses a rapid phase half-life of 6 hours or less
    • Roberts B. J., Shoaf S. E., Kyu-Shik J., Song B. J. Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: Evidence that CYP2E1 possesses a rapid phase half-life of 6 hours or less. Biochem. Biophys. Res. Commun. 205:1994;1064-1071.
    • (1994) Biochem. Biophys. Res. Commun. , vol.205 , pp. 1064-1071
    • Roberts, B.J.1    Shoaf, S.E.2    Kyu-Shik, J.3    Song, B.J.4
  • 34
    • 0029055831 scopus 로고
    • Rapid changes in cytochrome P4502E1 (CYP2E1) activity and other P450 isozymes following ethanol withdrawal in rats
    • Roberts B. J., Shoaf S. E., Song B. J. Rapid changes in cytochrome P4502E1 (CYP2E1) activity and other P450 isozymes following ethanol withdrawal in rats. Biochem. Pharmacol. 49:1995;1665-1673.
    • (1995) Biochem. Pharmacol. , vol.49 , pp. 1665-1673
    • Roberts, B.J.1    Shoaf, S.E.2    Song, B.J.3
  • 35
    • 0022499774 scopus 로고
    • Evidence that isoniazid and ethanol induce the same microsomal cytochrome P450 in rat liver, an isozyme homologous to rabbit liver cytochrome P450 isozyme 3a
    • Ryan D., Koop D., Thomas P., Coon M., Levin W. Evidence that isoniazid and ethanol induce the same microsomal cytochrome P450 in rat liver, an isozyme homologous to rabbit liver cytochrome P450 isozyme 3a. Arch. Biochem. Biophys. 246:1986;633-644.
    • (1986) Arch. Biochem. Biophys. , vol.246 , pp. 633-644
    • Ryan, D.1    Koop, D.2    Thomas, P.3    Coon, M.4    Levin, W.5
  • 36
    • 0019389575 scopus 로고
    • Prevention of acetaminophen-induced hepatoxicity by acute ethanol administration in the rat
    • Sato C., Nako M., Lieber C. S. Prevention of acetaminophen-induced hepatoxicity by acute ethanol administration in the rat. J. Pharmacol. Exp. Ther. 218:1981;811-815.
    • (1981) J. Pharmacol. Exp. Ther. , vol.218 , pp. 811-815
    • Sato, C.1    Nako, M.2    Lieber, C.S.3
  • 38
    • 0028015606 scopus 로고
    • Loss of CYP2E1 and CYP1A2 activity as a function of acetaminophen dose: Relation to toxicity
    • Snawder J. E., Roe A. L., Benson R. W., Roberts D. W. Loss of CYP2E1 and CYP1A2 activity as a function of acetaminophen dose: Relation to toxicity. Biochem. Biophys. Res. Commun. 203:1994;532-539.
    • (1994) Biochem. Biophys. Res. Commun. , vol.203 , pp. 532-539
    • Snawder, J.E.1    Roe, A.L.2    Benson, R.W.3    Roberts, D.W.4
  • 39
    • 0029058914 scopus 로고
    • Cytochrome P4502E1 inhibition by propylene glycol prevents acetaminophen (Paracetamol) hepatotoxicity in mice without cytochrome P4501A2 inhibition
    • Thomsen M., Loft S., Roberts D., Poulsen H. Cytochrome P4502E1 inhibition by propylene glycol prevents acetaminophen (Paracetamol) hepatotoxicity in mice without cytochrome P4501A2 inhibition. Pharmacol. Toxicol. 76:1995;395-399.
    • (1995) Pharmacol. Toxicol. , vol.76 , pp. 395-399
    • Thomsen, M.1    Loft, S.2    Roberts, D.3    Poulsen, H.4
  • 40
    • 0023888524 scopus 로고
    • Mechanism by which ethanol diminishes the hepatotoxicity of acetaminophen
    • Thummel K. E., Slattery J. T., Nelson S. D. Mechanism by which ethanol diminishes the hepatotoxicity of acetaminophen. J. Pharmacol. Exp. Ther. 245:1988;129-136.
    • (1988) J. Pharmacol. Exp. Ther. , vol.245 , pp. 129-136
    • Thummel, K.E.1    Slattery, J.T.2    Nelson, S.D.3
  • 41
    • 0024446203 scopus 로고
    • Effect of ethanol on hepatotoxicity of acetaminophen in mice and on reactive metabolite formation by mouse and human liver microsomes
    • Thummel K. E., Slattery J. T., Nelson S. D., Lee C. A., Pearson P. G. Effect of ethanol on hepatotoxicity of acetaminophen in mice and on reactive metabolite formation by mouse and human liver microsomes. Toxicol. Appl. Pharmacol. 100:1989;391-397.
    • (1989) Toxicol. Appl. Pharmacol. , vol.100 , pp. 391-397
    • Thummel, K.E.1    Slattery, J.T.2    Nelson, S.D.3    Lee, C.A.4    Pearson, P.G.5
  • 42
    • 0027253615 scopus 로고
    • Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human CYP3A4
    • Thummel K. E., Lee C. A., Kunze K. L., Nelson S. D., Slattery J. T. Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human CYP3A4. Biochem. Pharmacol. 5:1993;1563-1569.
    • (1993) Biochem. Pharmacol. , vol.5 , pp. 1563-1569
    • Thummel, K.E.1    Lee, C.A.2    Kunze, K.L.3    Nelson, S.D.4    Slattery, J.T.5
  • 45
    • 0023200612 scopus 로고
    • Purification and characterization of ethanol-inducible human hepatic cytochrome P450HLj
    • Wrighton S., Thomas P., Ryan D., Levin W. Purification and characterization of ethanol-inducible human hepatic cytochrome P450HLj. Arch. Biochem. Biophys. 258:1987;292-297.
    • (1987) Arch. Biochem. Biophys. , vol.258 , pp. 292-297
    • Wrighton, S.1    Thomas, P.2    Ryan, D.3    Levin, W.4
  • 46
    • 0025688972 scopus 로고
    • Role of cytochrome P450 in drug metabolism and hepatotoxicity
    • Watkins P. B. Role of cytochrome P450 in drug metabolism and hepatotoxicity. Semin. Liver. Dis. 10:1990;267-278.
    • (1990) Semin. Liver. Dis. , vol.10 , pp. 267-278
    • Watkins, P.B.1
  • 47
    • 0012317199 scopus 로고
    • Rate of increase in plasma levels of cytoplasmic and mitochondrial enzymes in experimental carbon tetrachloride hepatotoxicity
    • Zimmerman H. H., Kodera Y., West M. Rate of increase in plasma levels of cytoplasmic and mitochondrial enzymes in experimental carbon tetrachloride hepatotoxicity. J. Lab. Clin. Med. 66:1965;315-323.
    • (1965) J. Lab. Clin. Med. , vol.66 , pp. 315-323
    • Zimmerman, H.H.1    Kodera, Y.2    West, M.3
  • 48
    • 0029083319 scopus 로고
    • Acetaminophen (Paracetamol) hepatotoxicity with regular intake of alcohol: Analysis of instances of therapeutic misadventure
    • Zimmerman H. J., Maddrey W. C. Acetaminophen (Paracetamol) hepatotoxicity with regular intake of alcohol: Analysis of instances of therapeutic misadventure. Hepatology. 22:1995;767-773.
    • (1995) Hepatology , vol.22 , pp. 767-773
    • Zimmerman, H.J.1    Maddrey, W.C.2


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