Force measurements of human embryonic stem cell-derived cardiomyocytes in an in vitro transplantation model

Stem Cells

Volumn 25, Issue 1, 2007, Pages 174-180

  Pillekamp, Frank ^a   Reppel, Michael ^a   Rubenchyk, Olga ^a   Pfannkuche, Kurt ^a   Matzkies, Matthias ^a   Bloch, Wilhelm ^b   Sreeram, Narayanswami ^a   Brockmeier, Konrad ^a   Hescheler, Jürgen ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b GERMAN SPORT UNIVERSITY COLOGNE   (Germany)

Author keywords

Cell transplantation; Myocardial contraction; Myocardial infarction; Pluripotent stem cells; Transplants

Indexed keywords

ANIMAL TISSUE; ARTICLE; BIOMECHANICS; EMBRYO; EMBRYONIC STEM CELL; FREQUENCY MODULATION; HEART BEAT; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART VENTRICLE; HUMAN; HUMAN CELL; IN VITRO STUDY; MEASUREMENT; MOUSE; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; STEM CELL TRANSPLANTATION;

ANIMALS; ANIMALS, NEWBORN; CELL MOVEMENT; EMBRYONIC STEM CELLS; GLUCOSE; HEART; HUMANS; MICE; MODELS, BIOLOGICAL; MYOCARDIUM; MYOCYTES, CARDIAC; OXYGEN CONSUMPTION; STEM CELL TRANSPLANTATION;

MURINAE;

EID: 33845969824     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2006-0094     Document Type: Article

References (36)

1. Nugent HM, Edelman ER. Tissue engineering therapy for cardiovascular disease. Circ Res 2005;92:1068-1078.
2. Davani S, Deschaseaux F, Chalmers D et al. Can stem cells mend a broken heart? Cardiovasc Res 2005;65:305-316.
3. Doss MX, Koehler CI, Gissel C et al. Embryonic stem cells: A promising tool for cell replacement therapy. J Cell Mol Med 2004;8:465-473.
4. Laflamme MA, Murry CE. Regenerating the heart. Nat Biotechnol 2005;23:845-856.
5. Passier R, Mummery C. Cardiomyocyte differentiation from embryonic and adult stem cells. Curr Opin Biotechnol 2005;16:498-502.
6. Nygren JM, Jovinge S, Breitbach M et al. Bone marrow-derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation. Nat Med 2004;10:494-501.
7. Hescheler J, Fleischmann BK, Lentini S et al. Embryonic stem cells: A model to study structural and functional properties in cardiomyogenesis. Cardiovasc Res 1997;36:149-162.
8. Chien KR. Stem cells: Lost in translation. Nature 2004;428:607-608.
9. Pillekamp F, Reppel M, Dinkelacker V et al. Establishment and characterization of a mouse embryonic heart slice preparation. Cell Physiol Biochem 2005;16:127-132.
10. Zhang JG, Ghosh S, Ockleford CD et al. Characterization of an in vitro model for the study of the short and prolonged effects of myocardial ischaemia and reperfusion in man. Clin Sci (Lond) 2000;99:443-453.
11. Metzger JM, Lin WI, Samuelson LC. Transition of cardiac contractile sensitivity to calcium during the in vitro differentiation of mouse embryonic stem cells. J Cell Biol 1994;126:701-711.
12. 2+ handling and the role of sarcoplasmic reticulum in the contraction. STEM CELLS 2005;24:236-245.
13. Sys SU, de Keulenaer GW, Brutsaert DL. Reappraisal of the multicellular preparation for the in vitro physiopharmacological evaluation of myocardial performance. Adv Exp Med Biol 1998;453:441-450.
14. Wollert KC, Meyer GP, Lotz J et al. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: The BOOST randomised controlled clinical trial. Lancet 2004;364:141-148.
15. Roell W, Lu ZJ, Bloch W et al. Cellular cardiomyoplasty improves survival after myocardial injury. Circulation 2002;105:2435-2441.
16. Passier R, Oostwaard DW, Snapper J et al. Increased cardiomyocyte differentiation from human embryonic stem cells in serum-free cultures. STEM CELLS 2005;23:772-780.
17. Davis ME, Hsieh PC, Grodzinsky AJ et al. Custom design of the cardiac microenvironment with biomaterials. Circ Res 2005;97:8-15.
18. Baharvand H, Azarnia M, Parivar K et al. The effect of extracellular matrix on embryonic stem cell-derived cardiomyocytes. J Mol Cell Cardiol 2005;38:495-503.
19. Corda S, Samuel JL, Rappaport L. Extracellular matrix and growth factors during heart growth. Heart Fail Rev 2000;5:119-130.
20. Eisenberg CA, Burch JB, Eisenberg LM. Bone marrow cells transdifferentiate to cardiomyocytes when introduced into the embryonic heart. STEM CELLS 2006;24:1236-1245.
21. Kehat I, Kenyagin-Karsenti D, Snir M et al. Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J Clin Invest 2001;108:407-414.
22. Kostetskii I, Li J, Xiong Y et al. Induced deletion of the N-cadherin gene in the heart leads to dissolution of the intercalated disc structure. Circ Res 2005;96:346-354.
23. Franke WW, Borrmann CM, Grund C et al. The area composita of adhering junctions connecting heart muscle cells of vertebrates. I. Molecular definition in intercalated disks of cardiomyocytes by immunoelectron microscopy of desmosomal proteins. Eur J Cell Biol 2006;85:69-82.
24. Samarel AM. Costameres, focal adhesions, and cardiomyocyte mechanotransduction. Am J Physiol Heart Circ Physiol 2005;289:H2291-H2301.
25. Matsushita T, Oyamada M, Fujimoto K et al. Remodeling of cell-cell and cell-extracellular matrix interactions at the border zone of rat myocardial infarcts. Circ Res 1999;85:1046-1055.
26. He JQ, Ma Y, Lee Y et al. Human embryonic stem cells develop into multiple types of cardiac myocytes. Action potential characterization. Circ Res 2003;93:32-39.
27. Reppel M, Boettinger C, Hescheler J. Beta-adrenergic and muscarinic modulation of human embryonic stem cell-derived cardiomyocytes. Cell Physiol Biochem 2004;14:187-196.
28. Gomes PA, de Galvao KM, Mateus EF. Excitability of isolated hearts from rats during postnatal development. J Cardiovasc Electrophysiol 2002;13:355-360.
29. Laflamme MA, Gold J, Xu C et al. Formation of human myocardium in the rat heart from human embryonic stem cells. Am J Pathol 2005;167:663-671.
30. Manasek FJ. Histogenesis of the embryonic myocardium. Am J Cardiol 1970;25:149-168.
31. Fuchs F, Martyn DA. Length-dependent Ca(2+) activation in cardiac muscle: Some remaining questions. J Muscle Res Cell Motil 2005;26:199-212.
32. Schwinger RH, Brixius K, Bavendiek U et al. Effect of cyclopiazonic acid on the force-frequency relationship in human nonfailing myocardium. J Pharmacol Exp Therap 1997;283:286-292.
33. Maltsev VA, Rohwedel J, Hescheler J et al. Embryonic stem cells differentiate in vitro into cardiomyocytes representing sinusnodal, atrial and ventricular cell types. Mech Dev 1993;44:41-50.
34. Weisser J, Martin J, Bisping E et al. Influence of mild hypothermia on myocardial contractility and circulatory function. Basic Res Cardiol 2001;96:198-205.
35. Shattock MJ, Bers DM. Inotropic response to hypothermia and the temperature-dependence of ryanodine action in isolated and rat ventricular muscle: Implications for excitation-contraction coupling. Circ Res 1987;61:761-771.
36. Janssen PM, Stull LB, Marban E. Myofilament properties comprise the rate-limiting step for cardiac relaxation at body temperature in the rat. Am J Physiol Heart Circ Physiol 2002;282:H499-507.