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Volumn 106, Issue 2-3, 2007, Pages 145-153

Skatole metabolism in the intact pre-pubescent male pig: The relationship between hepatic enzyme activity and skatole concentrations in plasma and fat

Author keywords

Aldehyde oxidase; Boar taint; CYP2A; CYP2E1; Pig; Prepubescent; Steroid hormone; SULT1A1

Indexed keywords

SUS SCROFA;

EID: 33845958955     PISSN: 18711413     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.livsci.2006.07.009     Document Type: Article
Times cited : (23)

References (47)
  • 1
    • 33845951712 scopus 로고
    • Microbial production of skatole in digestive tract, aborption to portal vein blood and liver turnover in entire male pigs
    • Sørensen M.R. (Ed)
    • Agergaard N., and Jensen B.B. Microbial production of skatole in digestive tract, aborption to portal vein blood and liver turnover in entire male pigs. In: Sørensen M.R. (Ed). Proc. of the 44th Annual Meeting of the European Association for Animal Production vol. 2 (1993) 330-331
    • (1993) Proc. of the 44th Annual Meeting of the European Association for Animal Production , vol.2 , pp. 330-331
    • Agergaard, N.1    Jensen, B.B.2
  • 2
    • 0001239393 scopus 로고
    • Quality of meat from entire male pigs
    • Babol J., and Squires E.J. Quality of meat from entire male pigs. Food Res. Int. 28 (1995) 201-212
    • (1995) Food Res. Int. , vol.28 , pp. 201-212
    • Babol, J.1    Squires, E.J.2
  • 3
    • 0032011701 scopus 로고    scopus 로고
    • Relationship between oxidation and conjugation metabolism of skatole in pig liver and concentrations of skatole in fat
    • Babol J., Squires E.J., and Lundström K. Relationship between oxidation and conjugation metabolism of skatole in pig liver and concentrations of skatole in fat. J. Anim. Sci. 76 (1998) 829-838
    • (1998) J. Anim. Sci. , vol.76 , pp. 829-838
    • Babol, J.1    Squires, E.J.2    Lundström, K.3
  • 4
    • 0346639271 scopus 로고    scopus 로고
    • The effect of age on distribution of skatole and indole levels in entire male pigs in four breeds: Yorkshire, Landrace, Hampshire, and Duroc
    • Babol J., Zamaratskaia G., Juneja R.K., and Lundström K. The effect of age on distribution of skatole and indole levels in entire male pigs in four breeds: Yorkshire, Landrace, Hampshire, and Duroc. Meat Sci. 67 (2004) 351-358
    • (2004) Meat Sci. , vol.67 , pp. 351-358
    • Babol, J.1    Zamaratskaia, G.2    Juneja, R.K.3    Lundström, K.4
  • 5
    • 0012918014 scopus 로고    scopus 로고
    • Identification of selected metabolites of skatole in plasma and urine from pigs
    • Bæk C., Hansen-Møller J., Friis C., Cornett C., and Hansen S.H. Identification of selected metabolites of skatole in plasma and urine from pigs. J. Agric. Food Chem. 45 (1997) 2332-2340
    • (1997) J. Agric. Food Chem. , vol.45 , pp. 2332-2340
    • Bæk, C.1    Hansen-Møller, J.2    Friis, C.3    Cornett, C.4    Hansen, S.H.5
  • 6
    • 0021329179 scopus 로고
    • Bile salt sulfotransferase: alterations during maturation and non-inducibility during substrate ingestion
    • Balistreri W.F., Zimmer L., Suchy F.J., and Bove K.E. Bile salt sulfotransferase: alterations during maturation and non-inducibility during substrate ingestion. J. Lipid Res. 25 (1984) 228-235
    • (1984) J. Lipid Res. , vol.25 , pp. 228-235
    • Balistreri, W.F.1    Zimmer, L.2    Suchy, F.J.3    Bove, K.E.4
  • 9
    • 0028207922 scopus 로고
    • A review of the nutritional influences on reproduction in boars, bulls and rams
    • Brown B.W. A review of the nutritional influences on reproduction in boars, bulls and rams. Reprod. Nutr. Dev. 34 (1994) 89-114
    • (1994) Reprod. Nutr. Dev. , vol.34 , pp. 89-114
    • Brown, B.W.1
  • 10
    • 0023272095 scopus 로고
    • Human liver phenol sulfotransferase: assay conditions, biochemical properties and partial purification of isozymes of the thermostable form
    • Campbell N.R., VanLoon J.A., and Weinshilboum R.M. Human liver phenol sulfotransferase: assay conditions, biochemical properties and partial purification of isozymes of the thermostable form. Biochem. Pharmacol. 36 (1987) 1435-1446
    • (1987) Biochem. Pharmacol. , vol.36 , pp. 1435-1446
    • Campbell, N.R.1    VanLoon, J.A.2    Weinshilboum, R.M.3
  • 11
    • 0020402831 scopus 로고
    • Development and regulation of bile salt sulfotransferase in rat liver
    • Chen L.J., Kane B., Bujanover Y., and Thaler M.M. Development and regulation of bile salt sulfotransferase in rat liver. Biochim. Biophys. Acta 713 (1982) 358-364
    • (1982) Biochim. Biophys. Acta , vol.713 , pp. 358-364
    • Chen, L.J.1    Kane, B.2    Bujanover, Y.3    Thaler, M.M.4
  • 12
    • 0038847351 scopus 로고
    • Parallel measurements of indole and skatole (3-methylindole) in feces and blood plasma of pigs by HPLC
    • Claus R., Dehnhard M., Herzog A., Bernal-Barragan H., and Giménez T. Parallel measurements of indole and skatole (3-methylindole) in feces and blood plasma of pigs by HPLC. Livest. Prod. Sci. 34 (1993) 115-126
    • (1993) Livest. Prod. Sci. , vol.34 , pp. 115-126
    • Claus, R.1    Dehnhard, M.2    Herzog, A.3    Bernal-Barragan, H.4    Giménez, T.5
  • 13
    • 0038147025 scopus 로고    scopus 로고
    • Effects of butyrate on apoptosis in the pig colon and its consequences for skatole formation and tissue accumulation
    • Claus R., Lösel D., Lacorn M., Mentschel J., and Schenkel H. Effects of butyrate on apoptosis in the pig colon and its consequences for skatole formation and tissue accumulation. J. Anim. Sci. 81 (2003) 239-248
    • (2003) J. Anim. Sci. , vol.81 , pp. 239-248
    • Claus, R.1    Lösel, D.2    Lacorn, M.3    Mentschel, J.4    Schenkel, H.5
  • 14
    • 3042831563 scopus 로고    scopus 로고
    • Rearing piglets in a poor environment: developmental aspects of social stress in pigs
    • DeJonge F.H., Bokkers E.A., Shouten W.G., and Helmond F.A. Rearing piglets in a poor environment: developmental aspects of social stress in pigs. Physiol. Behav. 60 (1996) 389-396
    • (1996) Physiol. Behav. , vol.60 , pp. 389-396
    • DeJonge, F.H.1    Bokkers, E.A.2    Shouten, W.G.3    Helmond, F.A.4
  • 15
    • 0027267427 scopus 로고
    • High-performance liquid chromatographic method for the determination of 3-methylindole (skatole) and indole in adipose tissue of pigs
    • Denhard M., Claus R., Hillenbrand M., and Herzog A. High-performance liquid chromatographic method for the determination of 3-methylindole (skatole) and indole in adipose tissue of pigs. J. Chromatogr. 616 (1993) 205-209
    • (1993) J. Chromatogr. , vol.616 , pp. 205-209
    • Denhard, M.1    Claus, R.2    Hillenbrand, M.3    Herzog, A.4
  • 17
    • 0034119438 scopus 로고    scopus 로고
    • Metabolism of 3-methylindole by porcine liver microsomes: responsible cytochrome P450 enzymes
    • Diaz G.J., and Squires E.J. Metabolism of 3-methylindole by porcine liver microsomes: responsible cytochrome P450 enzymes. Toxicol. Sci. 55 (2000) 284-292
    • (2000) Toxicol. Sci. , vol.55 , pp. 284-292
    • Diaz, G.J.1    Squires, E.J.2
  • 18
    • 0034113567 scopus 로고    scopus 로고
    • Role of aldehyde oxidase in the hepatic in vitro metabolism of 3-methylindole in pigs
    • Diaz G.J., and Squires E.J. Role of aldehyde oxidase in the hepatic in vitro metabolism of 3-methylindole in pigs. J. Agric. Food Chem. 48 (2000) 833-837
    • (2000) J. Agric. Food Chem. , vol.48 , pp. 833-837
    • Diaz, G.J.1    Squires, E.J.2
  • 19
    • 0038171278 scopus 로고    scopus 로고
    • Phase II in vitro metabolism of 3-methylindole metabolites in porcine liver
    • Diaz G.J., and Squires E.J. Phase II in vitro metabolism of 3-methylindole metabolites in porcine liver. Xenobiotica 33 (2003) 485-498
    • (2003) Xenobiotica , vol.33 , pp. 485-498
    • Diaz, G.J.1    Squires, E.J.2
  • 20
    • 0021071610 scopus 로고
    • Serum estrogen concentrations during postnatal development in male pigs
    • Ford J.J. Serum estrogen concentrations during postnatal development in male pigs. Proc. Soc. Exp. Biol. Med. 174 (1983) 160-164
    • (1983) Proc. Soc. Exp. Biol. Med. , vol.174 , pp. 160-164
    • Ford, J.J.1
  • 23
    • 84972090835 scopus 로고
    • Influence of stocking rate and faeces deposition in the pen at different temperatures on skatole concentration (boar taint) in subcutaneous fat
    • Hansen L.L., Larsen A.E., Jensen B.B., Hansen-Møller J., and Barton-Gade P. Influence of stocking rate and faeces deposition in the pen at different temperatures on skatole concentration (boar taint) in subcutaneous fat. Anim. Prod. 59 (1994) 99-110
    • (1994) Anim. Prod. , vol.59 , pp. 99-110
    • Hansen, L.L.1    Larsen, A.E.2    Jensen, B.B.3    Hansen-Møller, J.4    Barton-Gade, P.5
  • 24
    • 84971928332 scopus 로고
    • The effects of dietary fiber, lactose and antibiotic on the levels of skatole and indole in faeces and subcutaneous fat in growing pigs
    • Hawe S.M., Walker N., and Moss B.W. The effects of dietary fiber, lactose and antibiotic on the levels of skatole and indole in faeces and subcutaneous fat in growing pigs. Anim. Prod. 54 (1992) 413-419
    • (1992) Anim. Prod. , vol.54 , pp. 413-419
    • Hawe, S.M.1    Walker, N.2    Moss, B.W.3
  • 26
    • 0002233286 scopus 로고    scopus 로고
    • Effect of liquid feed on microbial production of skatole in the hind gut, skatole absorption to portal vein blood and skatole deposition in back fat
    • Jensen W.K. (Ed)
    • Jensen B.B., Agergaard N., Hansen L.L., Mikkelsen L.L., Jensen M.T., and Laue A. Effect of liquid feed on microbial production of skatole in the hind gut, skatole absorption to portal vein blood and skatole deposition in back fat. In: Jensen W.K. (Ed). Skatole and Boar Taint (1998) 165-178
    • (1998) Skatole and Boar Taint , pp. 165-178
    • Jensen, B.B.1    Agergaard, N.2    Hansen, L.L.3    Mikkelsen, L.L.4    Jensen, M.T.5    Laue, A.6
  • 27
    • 17744417087 scopus 로고    scopus 로고
    • The detection of cytochrome P450 2E1 and its catalytic activity in rat testis
    • Jiang Y., Kuo C.L., Pernecky S.J., and Piper W.N. The detection of cytochrome P450 2E1 and its catalytic activity in rat testis. Biochem. Biophys. Res. Commun. 246 (1998) 578-583
    • (1998) Biochem. Biophys. Res. Commun. , vol.246 , pp. 578-583
    • Jiang, Y.1    Kuo, C.L.2    Pernecky, S.J.3    Piper, W.N.4
  • 29
    • 0026567713 scopus 로고
    • Oxidative and reductive metabolism by cytochrome P450 2E1
    • Koop D.R. Oxidative and reductive metabolism by cytochrome P450 2E1. FASEB J. 6 (1992) 724-730
    • (1992) FASEB J. , vol.6 , pp. 724-730
    • Koop, D.R.1
  • 30
    • 33745855132 scopus 로고    scopus 로고
    • Characterizing developmental changes in plasma and tissue skatole concentrations in the pre-pubescent intact male pig
    • Lanthier F., Lou Y., Terner M.A., and Squires E.J. Characterizing developmental changes in plasma and tissue skatole concentrations in the pre-pubescent intact male pig. J. Anim. Sci. 84 (2006) 1699-1708
    • (2006) J. Anim. Sci. , vol.84 , pp. 1699-1708
    • Lanthier, F.1    Lou, Y.2    Terner, M.A.3    Squires, E.J.4
  • 31
    • 1442310959 scopus 로고    scopus 로고
    • Molecular cloning and functional analysis of porcine SULT1A1 gene and its variant: a single mutation SULT1A1 causes a significant decrease in sulfation activity
    • Lin Z., Lou Y., and Squires E.J. Molecular cloning and functional analysis of porcine SULT1A1 gene and its variant: a single mutation SULT1A1 causes a significant decrease in sulfation activity. Mamm. Genome 15 (2004) 218-226
    • (2004) Mamm. Genome , vol.15 , pp. 218-226
    • Lin, Z.1    Lou, Y.2    Squires, E.J.3
  • 32
    • 3843060093 scopus 로고    scopus 로고
    • Molecular cloning, expression and functional characterization of the cytochrome P4502A6 gene in pig liver
    • Lin Z., Lou Y., and Squires E.J. Molecular cloning, expression and functional characterization of the cytochrome P4502A6 gene in pig liver. Anim. Genet. 35 (2004) 314-316
    • (2004) Anim. Genet. , vol.35 , pp. 314-316
    • Lin, Z.1    Lou, Y.2    Squires, E.J.3
  • 33
    • 0029828445 scopus 로고    scopus 로고
    • Ontogeny and hormonal basis of male-dominant rat hepatic sulfotransferase
    • Liu L., and Klassen C.D. Ontogeny and hormonal basis of male-dominant rat hepatic sulfotransferase. Mol. Pharmacol. 50 (1996) 565-572
    • (1996) Mol. Pharmacol. , vol.50 , pp. 565-572
    • Liu, L.1    Klassen, C.D.2
  • 34
    • 0009880436 scopus 로고    scopus 로고
    • Off-flavour in meat with particular emphasis on boar taint
    • Taylor S., Raimundo A., Severini M., and Smulders F.J.M. (Eds)
    • Lundström K., and Bonneau M. Off-flavour in meat with particular emphasis on boar taint. In: Taylor S., Raimundo A., Severini M., and Smulders F.J.M. (Eds). Meat Quality and Meat Packaging (1996) 137
    • (1996) Meat Quality and Meat Packaging , pp. 137
    • Lundström, K.1    Bonneau, M.2
  • 35
    • 0016980287 scopus 로고
    • Oxidative and conjugative metabolism of p-nitroanisole and p-nitrophenol in isolated rat liver cells
    • Moldeus P., Vadr H., and Berggren M. Oxidative and conjugative metabolism of p-nitroanisole and p-nitrophenol in isolated rat liver cells. Acta Pharmacol. Toxicol. Copenh. 39 (1976) 17-32
    • (1976) Acta Pharmacol. Toxicol. Copenh. , vol.39 , pp. 17-32
    • Moldeus, P.1    Vadr, H.2    Berggren, M.3
  • 36
    • 0024349184 scopus 로고    scopus 로고
    • Negishi, M., Lindberg, R., Burkhart, B., Ichikawa, T., Honkoski, P., Lang, M., 1989. Mouse steroid 15 alpha-hydroxylase gene family: identification of type II P-450(15)alpha as coumarin 7-hydroxylase. 28, 4169-4172.
  • 38
    • 0018672767 scopus 로고
    • Development of testosterone secretion in the fetal pig testis
    • Raeside J.I., and Middleton A.T. Development of testosterone secretion in the fetal pig testis. Biol. Reprod. 21 (1979) 985-989
    • (1979) Biol. Reprod. , vol.21 , pp. 985-989
    • Raeside, J.I.1    Middleton, A.T.2
  • 40
    • 0027546823 scopus 로고
    • Plasma levels of several androgens and estrogens form birth to puberty in male domestic pig
    • Schwarzenberger F., Toole G.S., Christie H.L., and Raeside J.I. Plasma levels of several androgens and estrogens form birth to puberty in male domestic pig. Acta Endocrinol. 128 (1993) 173-177
    • (1993) Acta Endocrinol. , vol.128 , pp. 173-177
    • Schwarzenberger, F.1    Toole, G.S.2    Christie, H.L.3    Raeside, J.I.4
  • 41
    • 0017388593 scopus 로고
    • Simple phenols and indols in anaerobically stored piggery wastes
    • Spoelstra S.F. Simple phenols and indols in anaerobically stored piggery wastes. J. Sci. Food Agric. 28 (1977) 415-423
    • (1977) J. Sci. Food Agric. , vol.28 , pp. 415-423
    • Spoelstra, S.F.1
  • 42
    • 0031230797 scopus 로고    scopus 로고
    • Relationship between cytochrome P450IIE1 in liver and levels of skatole and its metabolites in intact male pigs
    • Squires E.J., and Lundström K. Relationship between cytochrome P450IIE1 in liver and levels of skatole and its metabolites in intact male pigs. J. Anim. Sci. 75 (1997) 2506-2511
    • (1997) J. Anim. Sci. , vol.75 , pp. 2506-2511
    • Squires, E.J.1    Lundström, K.2
  • 43
    • 0002239575 scopus 로고
    • Developmental patterns of plasma dehydro-epiandrosterone sulfate and testosterone in male pigs
    • Tan H.S., and Raeside J.I. Developmental patterns of plasma dehydro-epiandrosterone sulfate and testosterone in male pigs. Anim. Reprod. Sci. 3 (1980) 73-81
    • (1980) Anim. Reprod. Sci. , vol.3 , pp. 73-81
    • Tan, H.S.1    Raeside, J.I.2
  • 44
    • 0031783832 scopus 로고    scopus 로고
    • In vivo age-related changes in hepatic drug-oxidizing capacity in humans
    • Tanaka E. In vivo age-related changes in hepatic drug-oxidizing capacity in humans. J. Clin. Pharm. Ther. 23 (1998) 247-255
    • (1998) J. Clin. Pharm. Ther. , vol.23 , pp. 247-255
    • Tanaka, E.1
  • 46
    • 33645810602 scopus 로고    scopus 로고
    • The role of CYP2A and CYP2E1 in the metabolism of 3-methylindole in primary cultured porcine hepatocytes
    • Terner M.A., Gilmore W.J., Lou Y., and Squires E.J. The role of CYP2A and CYP2E1 in the metabolism of 3-methylindole in primary cultured porcine hepatocytes. Drug Metab. Dispos. 34 (2006) 848-854
    • (2006) Drug Metab. Dispos. , vol.34 , pp. 848-854
    • Terner, M.A.1    Gilmore, W.J.2    Lou, Y.3    Squires, E.J.4
  • 47
    • 0018297290 scopus 로고
    • Microbial metabolites of tryptophan in the intestinal tract with special reference to skatole
    • Yokoyama M.T., and Carlson J.R. Microbial metabolites of tryptophan in the intestinal tract with special reference to skatole. Am. J. Clin. Nutr. 32 (1979) 173-178
    • (1979) Am. J. Clin. Nutr. , vol.32 , pp. 173-178
    • Yokoyama, M.T.1    Carlson, J.R.2


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