-
1
-
-
0018170362
-
A simple and sensitive assay of 7-ethoxycoumarin deethylation
-
Aitio, A. (1978). A simple and sensitive assay of 7-ethoxycoumarin deethylation. Anal. Biochem. 85, 488-491.
-
(1978)
Anal. Biochem.
, vol.85
, pp. 488-491
-
-
Aitio, A.1
-
2
-
-
0032013471
-
Hepatic metabolism of skatole in pigs by cytochrome P4502E1
-
Babol, J., Squires, E. J., and Lundström, K. (1998). Hepatic metabolism of skatole in pigs by cytochrome P4502E1. J. Anim. Sci. 76, 822-828.
-
(1998)
J. Anim. Sci.
, vol.76
, pp. 822-828
-
-
Babol, J.1
Squires, E.J.2
Lundström, K.3
-
3
-
-
4244197273
-
Identification and quantification of selected metabolites of skatole: Possibilities for metabolic profiling of pigs
-
September 1995; Milton Keynes, UK. Milton Keynes: INRA and MLC (184 p.)
-
Bæk, C. E., Hansen-Møller, J., Friis, C., and Hansen. (1995). Identification and quantification of selected metabolites of skatole: Possibilities for metabolic profiling of pigs. Proceedings of a Meeting of the E.A.A.P. Working Group: Production and Utilization of Meat from Entire Male Pigs, pp. 27-29. September 1995; Milton Keynes, UK. Milton Keynes: INRA and MLC (184 p.).
-
(1995)
Proceedings of a Meeting of the E.A.A.P. Working Group: Production and Utilization of Meat from Entire Male Pigs
, pp. 27-29
-
-
Bæk, C.E.1
Hansen-Møller, J.2
Friis, C.3
Hansen4
-
4
-
-
0028970047
-
Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9
-
Baldwin, S. J., Bloomer, J. C., Smith, G. J., Ayrton, A. D., Clarke, S. E., and Chenery, R. J. (1995). Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9. Xenobiotica 25, 261-170.
-
(1995)
Xenobiotica
, vol.25
, pp. 261-1170
-
-
Baldwin, S.J.1
Bloomer, J.C.2
Smith, G.J.3
Ayrton, A.D.4
Clarke, S.E.5
Chenery, R.J.6
-
5
-
-
0028174881
-
Evaluation of triacetyloleandomycin, alpha-naphthoflavone and diethyldithiocarbamate as selective chemical probes for inhibition of human cytochromes P450
-
Chang, T. K., Gonzalez, F. J., and Waxman, D. J. (1994). Evaluation of triacetyloleandomycin, alpha-naphthoflavone and diethyldithiocarbamate as selective chemical probes for inhibition of human cytochromes P450. Arch. Biochem. Biophys. 311, 437-442.
-
(1994)
Arch. Biochem. Biophys.
, vol.311
, pp. 437-442
-
-
Chang, T.K.1
Gonzalez, F.J.2
Waxman, D.J.3
-
6
-
-
0025239050
-
Oxidation of pyrazole by reconstituted systems containing cytochrome P-450 IIE1
-
Clejan, L. A. and Cederbaum, A. I. (1990). Oxidation of pyrazole by reconstituted systems containing cytochrome P-450 IIE1 Biochim. Biophys. Acta 1034, 233-237.
-
(1990)
Biochim. Biophys. Acta
, vol.1034
, pp. 233-237
-
-
Clejan, L.A.1
Cederbaum, A.I.2
-
7
-
-
0032853327
-
Identification of Phase I metabolites of 3-methylindole produced by pig liver microsomes
-
Diaz, G. J., Skordos, K.W. Yost, G. S., and Squires, E. J. (1999). Identification of Phase I metabolites of 3-methylindole produced by pig liver microsomes. Drug Metab. Dispos. 27, 1150-1156.
-
(1999)
Drug Metab. Dispos.
, vol.27
, pp. 1150-1156
-
-
Diaz, G.J.1
Skordos, K.W.2
Yost, G.S.3
Squires, E.J.4
-
8
-
-
0034113567
-
Role of aldehyde oxidase in the hepatic in vitro metabolism of 3-methylindole in pigs
-
in press
-
Diaz, G. J., and Squires, E. J. (2000). Role of aldehyde oxidase in the hepatic in vitro metabolism of 3-methylindole in pigs. J. Agric. Food Chem. (in press).
-
(2000)
J. Agric. Food Chem.
-
-
Diaz, G.J.1
Squires, E.J.2
-
9
-
-
0031149716
-
Inhibition of coumarin 7-hydroxylase activity in human liver microsomes
-
Draper, A. J., Madan, A., and Parkinson, A. (1997). Inhibition of coumarin 7-hydroxylase activity in human liver microsomes. Arch. Biochem. Biophys. 341, 47-61.
-
(1997)
Arch. Biochem. Biophys.
, vol.341
, pp. 47-61
-
-
Draper, A.J.1
Madan, A.2
Parkinson, A.3
-
10
-
-
0031962621
-
Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes
-
Eagling, V. A., Tjia, J. F., and Back, D. J. (1998). Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes. Br. J. Clin. Pharmacol. 45, 107-114.
-
(1998)
Br. J. Clin. Pharmacol.
, vol.45
, pp. 107-114
-
-
Eagling, V.A.1
Tjia, J.F.2
Back, D.J.3
-
11
-
-
0022852729
-
Inhibition of microsomal oxidation of ethanol by pyrazole and 4-methylpyrazole in vitro
-
Feierman, D. E., and Cederbaum, A. I. (1986). Inhibition of microsomal oxidation of ethanol by pyrazole and 4-methylpyrazole in vitro. Biochem J. 239, 671-677.
-
(1986)
Biochem J.
, vol.239
, pp. 671-677
-
-
Feierman, D.E.1
Cederbaum, A.I.2
-
12
-
-
0000382840
-
Colonic absorption of tryptophan metabolites in man
-
Fordtran, J. S., Scroggie, W. B., and Polter, D. E. (1964). Colonic absorption of tryptophan metabolites in man. J. Lab. Clin. Med. 64, 125-132.
-
(1964)
J. Lab. Clin. Med.
, vol.64
, pp. 125-132
-
-
Fordtran, J.S.1
Scroggie, W.B.2
Polter, D.E.3
-
13
-
-
0002213121
-
Organelles as tools in toxicology
-
A.W. Hayed, Ed., Raven Press, New York
-
Fowler, B. A., Kleinow, K. M., Squibb, K. S., Lucier, G. W., and Hayes, A. W. (1994). Organelles as tools in toxicology. In Principles and Methods of Toxicology, 3rd ed. (A.W. Hayed, Ed.), pp. 1201-1230. Raven Press, New York.
-
(1994)
Principles and Methods of Toxicology, 3rd Ed.
, pp. 1201-1230
-
-
Fowler, B.A.1
Kleinow, K.M.2
Squibb, K.S.3
Lucier, G.W.4
Hayes, A.W.5
-
15
-
-
0026035519
-
Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects
-
Guenguerich, F. P., Kim, D. H., and Iwasaki, M. (1991). Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects. Chem. Res. Toxicol. 4, 168-179.
-
(1991)
Chem. Res. Toxicol.
, vol.4
, pp. 168-179
-
-
Guenguerich, F.P.1
Kim, D.H.2
Iwasaki, M.3
-
16
-
-
8544278026
-
CYP2A6 gene polymorphism and risk of liver cancer and cirrhosis
-
Gullstén, H., Agúndez, J. A. G., Bénitez, J., Läärä, E., Ladero, J. M., Díaz-, Rubio, M., Fernandez-Salguero, P., Gonzalez, F., Rautio, A., Pelkonen, O., and Raunio, H. (1997). CYP2A6 gene polymorphism and risk of liver cancer and cirrhosis. Pharmacogenetics 7, 247-250.
-
(1997)
Pharmacogenetics
, vol.7
, pp. 247-250
-
-
Gullstén, H.1
Agúndez, J.A.G.2
Bénitez, J.3
Läärä, E.4
Ladero, J.M.5
Díaz-Rubio, M.6
Fernandez-Salguero, P.7
Gonzalez, F.8
Rautio, A.9
Pelkonen, O.10
Raunio, H.11
-
17
-
-
0028349086
-
Selective inhibitors of cytochromes P450
-
Halpert, J. R., Guenguerich, F. P., Bend, J. R., and Correia, M. A. (1994). Selective inhibitors of cytochromes P450. Toxicol. Appl. Pharmacol. 125, 163-175.
-
(1994)
Toxicol. Appl. Pharmacol.
, vol.125
, pp. 163-175
-
-
Halpert, J.R.1
Guenguerich, F.P.2
Bend, J.R.3
Correia, M.A.4
-
18
-
-
0024538329
-
Inhibition of 3-methylindole bioactivation by the cytochrome P-450 suicide substrates 1-aminobenzotriazole and α-methylbenzylaminobenzotriazole
-
Huijzer, J. C., Adams, J. D., Jr., Jaw, J., and Yost, G. S. (1989). Inhibition of 3-methylindole bioactivation by the cytochrome P-450 suicide substrates 1-aminobenzotriazole and α-methylbenzylaminobenzotriazole. Drug Metab. Dispos. 17, 37-42.
-
(1989)
Drug Metab. Dispos.
, vol.17
, pp. 37-42
-
-
Huijzer, J.C.1
Adams Jr., J.D.2
Jaw, J.3
Yost, G.S.4
-
19
-
-
84974251137
-
Microbial production of skatole in the hind gut of pigs given different diets and its relation to skatole deposition in backfat
-
Jensen, M. T., Cox, R. P., and Jensen, B. B. (1995). Microbial production of skatole in the hind gut of pigs given different diets and its relation to skatole deposition in backfat. Anim. Sci. 61, 293-304.
-
(1995)
Anim. Sci.
, vol.61
, pp. 293-304
-
-
Jensen, M.T.1
Cox, R.P.2
Jensen, B.B.3
-
20
-
-
0031848620
-
(R)-(+)-Menthofuran is a potent, mechanism-based inactivator of human liver cytochrome P450 2A6
-
Khojasteh-Bakht, S. C., Koenigs, L. L., Peter, R. M., Trager, W. F., and Nelson, S. D. (1998). (R)-(+)-Menthofuran is a potent, mechanism-based inactivator of human liver cytochrome P450 2A6. Drug Metab. Dispos. 26, 701-704.
-
(1998)
Drug Metab. Dispos.
, vol.26
, pp. 701-704
-
-
Khojasteh-Bakht, S.C.1
Koenigs, L.L.2
Peter, R.M.3
Trager, W.F.4
Nelson, S.D.5
-
21
-
-
0031451433
-
Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen
-
Koenigs, L. L., Peter, R. M., Thompson, S. J., Rettie, A. E., and Trager, W. F. (1997). Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen. Drug Metab. Dispos. 25, 1407-1415.
-
(1997)
Drug Metab. Dispos.
, vol.25
, pp. 1407-1415
-
-
Koenigs, L.L.1
Peter, R.M.2
Thompson, S.J.3
Rettie, A.E.4
Trager, W.F.5
-
22
-
-
0024976419
-
coli substrate specificity by mutation of a single amino-acid residue
-
coli substrate specificity by mutation of a single amino-acid residue. Nature 339, 632-634.
-
(1989)
Nature
, vol.339
, pp. 632-634
-
-
Lindberg, R.L.1
Negishi, M.2
-
23
-
-
0009880436
-
Off-flavour of meat with particular emphasis on boar taint
-
Taylor, S., Raimundo A., Severini, M., and Smulders, F. J. M., Eds., ECCEAMST, Utrecht, The Netherlands
-
Lundström, K., and Bonneau, M. (1996). Off-flavour of meat with particular emphasis on boar taint. In Meat Quality and Meat Packaging (Taylor, S., Raimundo A., Severini, M., and Smulders, F. J. M., Eds.), pp. 137-154. ECCEAMST, Utrecht, The Netherlands.
-
(1996)
Meat Quality and Meat Packaging
, pp. 137-154
-
-
Lundström, K.1
Bonneau, M.2
-
24
-
-
0000332017
-
Skatole levels in pigs selected for high lean-tissue growth rate on different dietary protein levels
-
Lundström, K., Malmfors, B., Stern, S., Rydhmer, L., Eliasson-Selling, L., Mortensen, A. B., and Mortensen, H. P. (1994). Skatole levels in pigs selected for high lean-tissue growth rate on different dietary protein levels. Livestock Prod. Sci. 38, 125-132.
-
(1994)
Livestock Prod. Sci.
, vol.38
, pp. 125-132
-
-
Lundström, K.1
Malmfors, B.2
Stern, S.3
Rydhmer, L.4
Eliasson-Selling, L.5
Mortensen, A.B.6
Mortensen, H.P.7
-
25
-
-
0001647474
-
Relationship between boar taint and skatole determination with a new analysis method
-
papers 8-11. Bristol. UK
-
Mortensen, A. B., and Sørensen, S. E. (1984). Relationship between boar taint and skatole determination with a new analysis method. Proceedings of the 30th Eur. Mtg. Meat Res. Workers, papers 8-11. P. 394. Bristol. UK.
-
(1984)
Proceedings of the 30th Eur. Mtg. Meat Res. Workers
, pp. 394
-
-
Mortensen, A.B.1
Sørensen, S.E.2
-
26
-
-
7144257874
-
A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502)
-
Nunoya, K., Yokoi, T., Kimura, K., Inoue, K., Kodama, T., Funayama, M., Nagashima, K., Funae, Y., Green, C., Kinoshita, M., and Kamataki, T. (1998). A new deleted allele in the human cytochrome P450 2A6 (CYP2A6) gene found in individuals showing poor metabolic capacity to coumarin and (+)-cis-3,5-dimethyl-2-(3-pyridyl)thiazolidin-4-one hydrochloride (SM-12502). Pharmacogenetics 8, 239-249.
-
(1998)
Pharmacogenetics
, vol.8
, pp. 239-249
-
-
Nunoya, K.1
Yokoi, T.2
Kimura, K.3
Inoue, K.4
Kodama, T.5
Funayama, M.6
Nagashima, K.7
Funae, Y.8
Green, C.9
Kinoshita, M.10
Kamataki, T.11
-
27
-
-
0023788246
-
Use of quinidine inhibition to define the role of the sparteine/debrisoquine cytochrome P450 in metoprolol oxidation by human liver microsomes
-
Otton, S. V., Crewe, H. K., Lennard, M. S., Tucker, G. T., and Woods, H. F. (1988). Use of quinidine inhibition to define the role of the sparteine/debrisoquine cytochrome P450 in metoprolol oxidation by human liver microsomes. J. Pharmacol. Exp. Ther. 247, 242-247.
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.247
, pp. 242-247
-
-
Otton, S.V.1
Crewe, H.K.2
Lennard, M.S.3
Tucker, G.T.4
Woods, H.F.5
-
29
-
-
0028237729
-
Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
-
Shimada, T., Yamazaki, H., Mimura, M., Inui, Y., and Guengerich, F. P. (1994). Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians. J. Pharmacol. Exp. Ther. 270, 414-423.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.270
, pp. 414-423
-
-
Shimada, T.1
Yamazaki, H.2
Mimura, M.3
Inui, Y.4
Guengerich, F.P.5
-
30
-
-
0022186670
-
Measurement of protein using bicinchoninic acid
-
Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K., Gartner, F. H., Provenzano, M. D., Fujimoto, E. K., Goeke, N. M., Olson, B. J., and Klenk, D. C. (1985). Measurement of protein using bicinchoninic acid. Anal. Biochem. 150, 76-85.
-
(1985)
Anal. Biochem.
, vol.150
, pp. 76-85
-
-
Smith, P.K.1
Krohn, R.I.2
Hermanson, G.T.3
Mallia, A.K.4
Gartner, F.H.5
Provenzano, M.D.6
Fujimoto, E.K.7
Goeke, N.M.8
Olson, B.J.9
Klenk, D.C.10
-
31
-
-
0031230797
-
Relationship between cytochrome P450IIE1 in liver and levels of skatole and its metabolites in intact male pigs
-
Squires, E. J., and Lundström, K. (1997). Relationship between cytochrome P450IIE1 in liver and levels of skatole and its metabolites in intact male pigs. J. Anim. Sci. 75, 2506-2511.
-
(1997)
J. Anim. Sci.
, vol.75
, pp. 2506-2511
-
-
Squires, E.J.1
Lundström, K.2
-
32
-
-
0029875880
-
Metabolism of 3-methylindole by vaccinia-expressed P450 enzymes: Correlation of 3-methyleneindolenine formation and protein-binding
-
Thornton-Manning, J., Appleton, M. L., Gonzalez, F. J., and Yost, G. S. (1996). Metabolism of 3-methylindole by vaccinia-expressed P450 enzymes: Correlation of 3-methyleneindolenine formation and protein-binding. J. Pharmacol. Exp. Ther. 276, 21-29.
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.276
, pp. 21-29
-
-
Thornton-Manning, J.1
Appleton, M.L.2
Gonzalez, F.J.3
Yost, G.S.4
-
33
-
-
0026329745
-
Metabolic activation of the pneumotoxin, 3-methylindole, by vaccinia-expressed cytochrome P450s
-
Thornton-Manning, J. R., Ruangyuttikarn, W., Gonzalez, F. J., and Yost, G. S. (1991). Metabolic activation of the pneumotoxin, 3-methylindole, by vaccinia-expressed cytochrome P450s. Biochem. Biophys. Res. Commun. 181, 100-107.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.181
, pp. 100-107
-
-
Thornton-Manning, J.R.1
Ruangyuttikarn, W.2
Gonzalez, F.J.3
Yost, G.S.4
-
34
-
-
0025022689
-
The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
-
Yamano, S., Tatsuno, J., and Gonzalez, F. J. (1990). The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes. Biochemistry 29, 1322-1329.
-
(1990)
Biochemistry
, vol.29
, pp. 1322-1329
-
-
Yamano, S.1
Tatsuno, J.2
Gonzalez, F.J.3
-
35
-
-
0026744568
-
Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes
-
Yamazaki, H., Inui, Y., Yun, C. H., Guengerich, F. P., and Shimada, T. (1992). Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes. Carcinogenesis 13, 1789-1794.
-
(1992)
Carcinogenesis
, vol.13
, pp. 1789-1794
-
-
Yamazaki, H.1
Inui, Y.2
Yun, C.H.3
Guengerich, F.P.4
Shimada, T.5
-
36
-
-
0031769798
-
Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6β-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin
-
Yamazaki, H., and Shimada, T. (1998). Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6β-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin. Drug Metab. Dispos. 26, 1053-1057.
-
(1998)
Drug Metab. Dispos.
, vol.26
, pp. 1053-1057
-
-
Yamazaki, H.1
Shimada, T.2
-
37
-
-
0018297290
-
Microbial metabolites of tryptophan in the intestinal tract with special reference to skatole
-
Yokoyama, M. T., and Carlson, J. R. (1979). Microbial metabolites of tryptophan in the intestinal tract with special reference to skatole. Am. J. Clin. Nutr. 32, 173-178.
-
(1979)
Am. J. Clin. Nutr.
, vol.32
, pp. 173-178
-
-
Yokoyama, M.T.1
Carlson, J.R.2
|