Three complement-like repeats compose the complete α2- macroglobulin binding site in the second ligand binding cluster of the low density lipoprotein receptor-related protein

Journal of Biological Chemistry

Volumn 281, Issue 45, 2006, Pages 34189-34196

  Dolmer, Klavs ^a   Gettins, Peter G W ^a,b  

^a UNIVERSITY OF ILLINOIS   (United States)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELLS; GENETIC ENGINEERING; MOLECULAR BIOLOGY; PHYSIOLOGICAL MODELS;

LIGANDS; LIPOPROTEIN RECEPTOR-RELATED PROTEIN (LRP); RECEPTOR BINDING DOMAIN (RBD);

PROTEINS;

ALPHA 2 MACROGLOBULIN; COMPLEMENT; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN;

ARTICLE; BINDING SITE; ENDOCYTOSIS; LIGAND BINDING; PH; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; THEORETICAL MODEL;

ALPHA-MACROGLOBULINS; BINDING SITES; CALCIUM; HUMANS; INTEGRIN ALPHAXBETA2; LDL-RECEPTOR RELATED PROTEINS; LIGANDS; MACROPHAGE-1 ANTIGEN; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; SPECTROMETRY, FLUORESCENCE;

EID: 33845931332     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M604389200     Document Type: Article

References (45)

1. Herz, J., Clouthier, D. E., and Hammer, R. E. (1992) Cell 71, 411-421
2. Herz, J., and Strickland, D. K. (2001) J. Clin. Investig. 108, 779-784
3. Catterall, C. F., Lyons, A., Sim, R. B., Day, A. J., and Harris, T. J. (1987) Biochem. J. 242, 849-856
4. Herz, J., Hamann, U., Rogne, S., Myklebost, O., Gausepohl, H., and Stanley, K. K. (1988) EMBO J. 7, 4119-4127
5. Kristensen, T., Moestrup, S. K., Gliemann, J., Bendtsen, L., Sand, O., and Sottrup-Jensen, L. (1990) FEBS Lett. 276, 151-155
6. Strickland, D. K., Ashcom, J. D., Williams, S., Burgess, W. H., Migliorini, M., and Argraves, W. S. (1990) J. Biol. Chem. 265, 17401-17404
7. Beglova, N., North, C. L., and Blacklow, S. C. (2001) Biochemistry 40, 2808-2815
8. Simonovic, M., Dolmer, K., Huang, W., Strickland, D. K., Volz, K., and Gettins, P. G. W. (2001) Biochemistry 40, 15127-15134
9. Sottrup-Jensen, L. (1989) J. Biol. Chem. 264, 11539-11542
10. Crookston, K. P., Webb, D. J., LaMarre, J., and Gonias, S. L. (1993) Biochem. J. 293, 443-450
11. Sottrup-Jensen, L., Stepanik, T. M., Kristensen, T., Lqnblad, P. B., Jones, C. M., Wierzbicki, D. M., Magnusson, S., Domdey, P. B., Wetsel, R. A., Lundwall, Å., Tack, B. F., and Fey, G. H. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 9-13
12. Lutz, C., Nimpf, J., Jenny, M., Boecklinger, K., Enzinger, C., Utermann, G., Baier-Bitterlich, G., and Baier, G. (2002) J. Biol. Chem. 277, 43143-43151
13. Huang, W., Dolmer, K., Liao, X., and Gettins, P. G. W. (2000) J. Biol. Chem. 275, 1089-1094
14. Van Leuven, F., Marynen, P., Cassiman, J.-J., and Van den Berghe, H. (1982) Biochem. J. 203, 405-411
15. Sottrup-Jensen, L., Gliemann, J., and Van Leuven, F. (1986) FEBS Lett. 205, 20-24
16. Enghild, J. J., Thøgersen, I., B., Roche, P. A., and Pizzo, S. V. (1989) Biochemistry 28, 1406-1412
17. Neels, J. G., Van den Berg, B. M. M., Lookene, A., Olivecrona, G., Pannekoek, H. P., and van Zonneveld, A.-J. (1999) J. Biol. Chem. 274, 31305-31311
18. Nielsen, K. L., Holtet, T. L., Etzerodt, M., Moestrup, S. K., Gliemann, J., Sottrup-Jensen, L., and Thogersen, H. C. (1996) J. Biol. Chem. 271, 12909-12912
19. Dolmer, K., Huang, W., and Gettins, P. G. W. (2000) J. Biol. Chem. 275, 3264-3271
20. Rudenko, G., Henry, L., Henderson, K., Ichtchenko, K., Brown, M. S., Goldstein, J. L., and Deisenhofer, J. (2002) Science 298, 2353-2358
21. Huang, W., Dolmer, K., Liao, X. B., and Gettins, P. G. W. (1998) Protein Sci. 7, 2602-2612
22. Oganesyan, N., Kim, S.-H., and Kim, R. (2005) J. Struct. Funct. Genomics 6, 177-182
23. Dolmer, K., Huang, W., and Gettins, P. G. W. (1998) Biochemistry 37, 17016-17023
24. Pace, C. N., Vajdos, F., Grimsley, G., and Gray, T. (1995) Protein Sci. 4, 2411-2423
25. Blacklow, S. C., and Kim, P. S. (1996) Nat. Struct. Biol. 3, 758-761
26. Willnow, T. E., Armstrong, S. A., Hammer, R. E., and Herz, J. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 4537-4541
27. Bu, G., and Rennke, S. (1996) J. Biol. Chem. 271, 22218-22224
28. Arandjelovic, S., Hall, B. D., and Gonias, S. L. (2005) Arch. Biochem. Biophys. 438, 29-35
29. Moestrup, S. K., Kaltoft, K., Sottrup-Jensen, L., and Gliemann, J. (1990) J. Biol. Chem. 265, 12623-12628
30. Brown, M. S., Herz, J., and Goldstein, J. L. (1997) Nature 388, 629-630
31. Mikhailenko, I., Battey, F. D., Migliorini, M., Ruiz, J. F., Argraves, K., Moayeri, M., and Strickland, D. K. (2001) J. Biol. Chem. 276, 39484-39491
32. Moestrup, S. K., and Gliemann, J. (1991) J. Biol. Chem. 266, 14011-14017
33. Lewis, S. D., Shields, P. P., and Shafer, J. A. (1985) J. Biol. Chem. 260, 10192-10199
34. Fisher, C., Beglova, N., and Blacklow, S. C. (2006) Mol. Cell 22, 277-283
35. Migliorini, M., Behre, E. H., Brew, S., Ingham, K. C., and Strickland, D. K. (2003) J. Biol. Chem. 278, 17986-17992
36. Rodenburg, K. W., Kjoller, L., Petersen, H. H., and Andreasen, P. A. (1998) Biochem. J. 329, 55-63
37. Stefansson, S., Muhammad, S., Cheng, X. F., Battey, F. D., Strickland, D. K., and Lawrence, D. A. (1998) J. Biol. Chem. 273, 6358-6366
38. Lalazar, A., Weisgraber, K. H., Rall, S. C. J., Giladi, H., Innerarity, T. L., Levanon, A. Z., Boyles, J. K., Amit, B., Gorecki, M., and Mahley, R. W. (1988) J. Biol. Chem. 263, 3542-3545
39. Andersen, O. M., Christensen, P. A., Christensen, L. L., Jacobsen, C., Moestrup, S. K., Etzerodt, M., and Thøgersen, H. C. (2000) Biochemistry 39, 10627-10633
40. Willnow, T. E., Orth, K., and Herz, J. (1994) J. Biol. Chem. 269, 15827-15832
41. Obermoeller-McCormick, L. M., Li, Y., Osaka, H., FitzGerald, D. J., Schwartz, A. L., and Bu, G. (2001) J. Cell Sci. 114, 899-908
42. Verdaguer, N., Fita, I., Reithmayer, M., Moser, R., and Blaas, D. (2004) Nat. Struct. Biol. 11, 429-434
43. Andersen, O. M., Christensen, L. L., Christensen, P. A., Sorensen, E. S., Jacobsen, C., Moestrup, S. K., Etzerodt, M., and Thøgersen, H. C. (2000) J. Biol. Chem. 275, 21017-21024
44. Silverman, J., Liu, Q., Bakker, A., To, W., Duguay, A., Alba, B. M., Smith, R., Rivas, A., Li, P., Whitehorn, E., Moore, K. W., Swimmer, C., Perlroth, V., Vogt, M., Kolkman, J., and Stemmer, W. P. C. (2005) Nat. Biotechnol. 23, 1556-1561
45. Jeong, K. J., Mabry, R., and Georgiu, G. (2005) Nat. Biotechnol. 23, 1493-1494