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Volumn 26, Issue 6 B, 2006, Pages 4079-4092

Analysis of a mutant p53 protein arising in a medulloblastoma from a mouse transgenic for the JC virus early region

Author keywords

JC virus; Medulloblastoma; Neurooncogenesis; p53; T antigen

Indexed keywords

MUTANT PROTEIN; PROTEIN P53; VIRUS T ANTIGEN;

EID: 33845923106     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (21)

References (44)
  • 1
    • 33745616856 scopus 로고    scopus 로고
    • The polyomavirus, JCV, and its involvement in human disease
    • Khalili K, Gordon J and White MK: The polyomavirus, JCV, and its involvement in human disease. Adv Exp Med Biol 577: 274-287, 2006.
    • (2006) Adv Exp Med Biol , vol.577 , pp. 274-287
    • Khalili, K.1    Gordon, J.2    White, M.K.3
  • 2
    • 2942536157 scopus 로고    scopus 로고
    • Polyomaviruses and human cancer: Molecular mechanisms underlying patterns of tumorigenesis
    • White MK and Khalili K: Polyomaviruses and human cancer: molecular mechanisms underlying patterns of tumorigenesis. Virology 324: 1-16, 2004.
    • (2004) Virology , vol.324 , pp. 1-16
    • White, M.K.1    Khalili, K.2
  • 4
    • 27544503617 scopus 로고    scopus 로고
    • Expression of JC virus regulatory proteins in human cancer: Potential mechanisms for tumourigenesis
    • White MK and Khalili K: Expression of JC virus regulatory proteins in human cancer: potential mechanisms for tumourigenesis. Eur J Cancer 41: 2537-2548, 2005.
    • (2005) Eur J Cancer , vol.41 , pp. 2537-2548
    • White, M.K.1    Khalili, K.2
  • 5
    • 0036660979 scopus 로고    scopus 로고
    • Medulloblastomas and primitive neuroectodermal tumors rarely contain polyomavirus DNA sequences
    • Kim JY, Koralnik IJ, LeFave M, Segal RA, Pfister LA and Pomeroy SL: Medulloblastomas and primitive neuroectodermal tumors rarely contain polyomavirus DNA sequences. Neurooncol 4: 165-170, 2002.
    • (2002) Neurooncol , vol.4 , pp. 165-170
    • Kim, J.Y.1    Koralnik, I.J.2    LeFave, M.3    Segal, R.A.4    Pfister, L.A.5    Pomeroy, S.L.6
  • 7
    • 27144510386 scopus 로고    scopus 로고
    • Gordon J, Del Valle L, Croul S, Reiss K, White M and Khalili K: Re: Investigation of human brain tumors for the presence of polyomavirus genome sequences by two independent laboratories by Rollison et al. Int J Cancer 117: 693-694, 2005.
    • Gordon J, Del Valle L, Croul S, Reiss K, White M and Khalili K: Re: Investigation of human brain tumors for the presence of polyomavirus genome sequences by two independent laboratories by Rollison et al. Int J Cancer 117: 693-694, 2005.
  • 11
    • 0012084884 scopus 로고
    • Early regions of JC virus and BK virus induce distinct and tissue-specific tumors in transgenic mice
    • Small JA, Khoury G, Jay G, Howley PM and Scangos GA: Early regions of JC virus and BK virus induce distinct and tissue-specific tumors in transgenic mice. Proc Natl Acad Sci USA 83: 8288-8292, 1986.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 8288-8292
    • Small, J.A.1    Khoury, G.2    Jay, G.3    Howley, P.M.4    Scangos, G.A.5
  • 12
    • 0029993162 scopus 로고    scopus 로고
    • Formation of undifferentiated mesenteric tumors in transgenic mice expressing human neurotropic polymavirus early protein
    • Franks RR, Rencic A, Gordon J, Zoltick PW, Curtis M, Knobler RL and Khalili K: Formation of undifferentiated mesenteric tumors in transgenic mice expressing human neurotropic polymavirus early protein. Oncogene 12: 2573-2578, 1996.
    • (1996) Oncogene , vol.12 , pp. 2573-2578
    • Franks, R.R.1    Rencic, A.2    Gordon, J.3    Zoltick, P.W.4    Curtis, M.5    Knobler, R.L.6    Khalili, K.7
  • 13
    • 0034609749 scopus 로고    scopus 로고
    • Pituitary neoplasia induced by expression of human neurotropic polyomavirus, JCV, early genome in transgenic mice
    • Gordon J, Del Valle L, Otte J and Khalili K: Pituitary neoplasia induced by expression of human neurotropic polyomavirus, JCV, early genome in transgenic mice. Oncogene 19: 4840-4846, 2000.
    • (2000) Oncogene , vol.19 , pp. 4840-4846
    • Gordon, J.1    Del Valle, L.2    Otte, J.3    Khalili, K.4
  • 14
    • 3843136342 scopus 로고    scopus 로고
    • JCV T-antigen interacts with the neurofibromatosis type 2 gene product in a transgenic mouse model of malignant peripheral nerve sheath tumors
    • Shollar D, Del Valle L, Khalili K, Otte J and Gordon J: JCV T-antigen interacts with the neurofibromatosis type 2 gene product in a transgenic mouse model of malignant peripheral nerve sheath tumors. Oncogene 23: 5459-5467, 2004.
    • (2004) Oncogene , vol.23 , pp. 5459-5467
    • Shollar, D.1    Del Valle, L.2    Khalili, K.3    Otte, J.4    Gordon, J.5
  • 15
    • 0033531233 scopus 로고    scopus 로고
    • Human ubiquitous JCV(CY) T-antigen gene induces brain tumors in experimental animals
    • Krynska B, Otte J, Franks R, Khalili K and Croul S: Human ubiquitous JCV(CY) T-antigen gene induces brain tumors in experimental animals. Oncogene 18: 39-46, 1999.
    • (1999) Oncogene , vol.18 , pp. 39-46
    • Krynska, B.1    Otte, J.2    Franks, R.3    Khalili, K.4    Croul, S.5
  • 16
    • 0041465953 scopus 로고    scopus 로고
    • Human neurotropic polyomavirus, JCV, and its role in carcinogenesis
    • Khalili K, Del Valle L, Otte J, Weaver M and Gordon J: Human neurotropic polyomavirus, JCV, and its role in carcinogenesis. Oncogene 22: 5181-5191, 2003.
    • (2003) Oncogene , vol.22 , pp. 5181-5191
    • Khalili, K.1    Del Valle, L.2    Otte, J.3    Weaver, M.4    Gordon, J.5
  • 19
    • 0034663401 scopus 로고    scopus 로고
    • Identification of a novel p53 mutation in JCV-induced mouse medulloblastoma
    • Krynska B, Del Valle L, Gordon J, Otte J, Croul S and Khalili K: Identification of a novel p53 mutation in JCV-induced mouse medulloblastoma. Virology 274: 65-74, 2000.
    • (2000) Virology , vol.274 , pp. 65-74
    • Krynska, B.1    Del Valle, L.2    Gordon, J.3    Otte, J.4    Croul, S.5    Khalili, K.6
  • 20
    • 0033613087 scopus 로고    scopus 로고
    • Detection of human neurotropic JC virus DNA sequence and expression of the viral oncogenic protein in pediatric medulloblastomas
    • Krynska B, Del Valle L, Croul S, Gordon J, Katsetos CD, Carbone M, Giordano A and Khalili K: Detection of human neurotropic JC virus DNA sequence and expression of the viral oncogenic protein in pediatric medulloblastomas. Proc Natl Acad Sci USA 96: 11519-11524, 1999.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 11519-11524
    • Krynska, B.1    Del Valle, L.2    Croul, S.3    Gordon, J.4    Katsetos, C.D.5    Carbone, M.6    Giordano, A.7    Khalili, K.8
  • 21
    • 0033518971 scopus 로고    scopus 로고
    • Medulloblastomas and the human neurotropic polyomavirus JC virus
    • Khalili K, Krynska B, Del Valle L, Katsetos CD and Croul S: Medulloblastomas and the human neurotropic polyomavirus JC virus. Lancet 353: 1152-1153, 1999.
    • (1999) Lancet , vol.353 , pp. 1152-1153
    • Khalili, K.1    Krynska, B.2    Del Valle, L.3    Katsetos, C.D.4    Croul, S.5
  • 23
    • 0035152379 scopus 로고    scopus 로고
    • Interaction of JC virus agno protein with T antigen modulates transcription and replication of the viral genome in glial cells
    • Safak M, Barrucco R, Darbinyan A, Okada Y, Nagashima K and Khalili K: Interaction of JC virus agno protein with T antigen modulates transcription and replication of the viral genome in glial cells. J Virol 75: 1476-1486, 2001.
    • (2001) J Virol , vol.75 , pp. 1476-1486
    • Safak, M.1    Barrucco, R.2    Darbinyan, A.3    Okada, Y.4    Nagashima, K.5    Khalili, K.6
  • 26
    • 0032484017 scopus 로고    scopus 로고
    • Interaction of the single-stranded DNA-binding protein Puralpha with the human polyomavirus JC virus early protein T-antigen
    • Gallia GL, Safak M and Khalili K: Interaction of the single-stranded DNA-binding protein Puralpha with the human polyomavirus JC virus early protein T-antigen. J Biol Chem 273: 32662-32669, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 32662-32669
    • Gallia, G.L.1    Safak, M.2    Khalili, K.3
  • 29
    • 0027501841 scopus 로고
    • Wild type p53 can mediate sequence-specific transactivation of an internal promoter within the mdm2 gene
    • Juven T, Barak Y, Zauberman A, George DL and Oren M: Wild type p53 can mediate sequence-specific transactivation of an internal promoter within the mdm2 gene. Oncogene 8: 3411-3416, 1993.
    • (1993) Oncogene , vol.8 , pp. 3411-3416
    • Juven, T.1    Barak, Y.2    Zauberman, A.3    George, D.L.4    Oren, M.5
  • 31
    • 0015232447 scopus 로고
    • Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy
    • Padgett BL, Walker DL, ZuRhein GM, Eckroade RJ and Dessel BH: Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy. Lancet 1: 1257-1260, 1971.
    • (1971) Lancet 1 , vol.1257-1260
    • Padgett, B.L.1    Walker, D.L.2    ZuRhein, G.M.3    Eckroade, R.J.4    Dessel, B.H.5
  • 32
    • 0025047207 scopus 로고
    • Mutagenic activity of BKV and JCV in human and other mammalian cells
    • Theile M and Grabowski G: Mutagenic activity of BKV and JCV in human and other mammalian cells. Arch Virol 113: 221-233, 1990.
    • (1990) Arch Virol , vol.113 , pp. 221-233
    • Theile, M.1    Grabowski, G.2
  • 33
    • 0030568053 scopus 로고    scopus 로고
    • High titers of antibodies to two human polyomaviruses, JCV and BKV, correlate with increased frequency of chromosomal damage in human lymphocytes
    • Lazutka JR, Neel JV, Major EO, Dedonyte V, Mierauskine J, Slapsyte G and Kesminiene A: High titers of antibodies to two human polyomaviruses, JCV and BKV, correlate with increased frequency of chromosomal damage in human lymphocytes. Cancer Lett 109: 177-183, 1996.
    • (1996) Cancer Lett , vol.109 , pp. 177-183
    • Lazutka, J.R.1    Neel, J.V.2    Major, E.O.3    Dedonyte, V.4    Mierauskine, J.5    Slapsyte, G.6    Kesminiene, A.7
  • 34
    • 0029924204 scopus 로고    scopus 로고
    • Hypothesis: "Rogue cell"-type chromosomal damage in lymphocytes is associated with infection with the JC human polyoma virus and has implications for oncopenesis
    • Neel JV, Major EO, Awa AA, Glover T, Burgess A, Traub R, Curfman B and Satoh C: Hypothesis: "Rogue cell"-type chromosomal damage in lymphocytes is associated with infection with the JC human polyoma virus and has implications for oncopenesis. Proc Natl Acad Sci USA 93: 2690-2695, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2690-2695
    • Neel, J.V.1    Major, E.O.2    Awa, A.A.3    Glover, T.4    Burgess, A.5    Traub, R.6    Curfman, B.7    Satoh, C.8
  • 36
    • 0025115324 scopus 로고
    • SV40 T antigen alone drives karyotype instability that precedes neoplastic transformation of human diploid fibroblasts
    • Ray FA, Peabody DS, Cooper JL, Cram LS and Kraemer PM: SV40 T antigen alone drives karyotype instability that precedes neoplastic transformation of human diploid fibroblasts. J Cell Biochem 42: 13-31, 1990.
    • (1990) J Cell Biochem , vol.42 , pp. 13-31
    • Ray, F.A.1    Peabody, D.S.2    Cooper, J.L.3    Cram, L.S.4    Kraemer, P.M.5
  • 37
    • 0026458549 scopus 로고
    • SV40 T antigen induced chromosomal changes reflect a process that is both clastogenic and aneuploidogenic and is ongoing throughout neoplastic progression of human fibroblasts
    • Ray FA, Meyne J and Kraemer PM: SV40 T antigen induced chromosomal changes reflect a process that is both clastogenic and aneuploidogenic and is ongoing throughout neoplastic progression of human fibroblasts. Mutat Res 284: 265-273, 1992.
    • (1992) Mutat Res , vol.284 , pp. 265-273
    • Ray, F.A.1    Meyne, J.2    Kraemer, P.M.3
  • 39
    • 0025731379 scopus 로고
    • Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation
    • Milner J and Medcalf EA: Cotranslation of activated mutant p53 with wild type drives the wild-type p53 protein into the mutant conformation. Cell 65: 765-774, 1991.
    • (1991) Cell , vol.65 , pp. 765-774
    • Milner, J.1    Medcalf, E.A.2
  • 40
    • 0033809941 scopus 로고    scopus 로고
    • p53 from complexity to simplicity: Mutant p53 stabilization, gain-of-function, and dominant-negative effect
    • Blagosklonny MV: p53 from complexity to simplicity: mutant p53 stabilization, gain-of-function, and dominant-negative effect. FASEB J 14: 1901-1907, 2000.
    • (2000) FASEB J , vol.14 , pp. 1901-1907
    • Blagosklonny, M.V.1
  • 41
    • 24644438102 scopus 로고    scopus 로고
    • Apoptosis. p53 and PUMA: A deadly duo
    • Vousden KH: Apoptosis. p53 and PUMA: a deadly duo. Science 309: 1685-1685, 2005.
    • (2005) Science , vol.309 , pp. 1685-1685
    • Vousden, K.H.1
  • 42
    • 24644457314 scopus 로고    scopus 로고
    • Complicating the complexity of p53
    • Yee KS and Vousden KH: Complicating the complexity of p53. Carcinogenesis 26: 1317-1322, 2005.
    • (2005) Carcinogenesis , vol.26 , pp. 1317-1322
    • Yee, K.S.1    Vousden, K.H.2
  • 43
    • 0030931636 scopus 로고    scopus 로고
    • Role of cell cycle regulators in tumor formation in transgenic mice expressing the human neurotropic virus, JCV, early protein
    • Krynska B, Gordon J, Otte J, Franks R, Knobler R, DeLuca A, Giordano A and Khalili K: Role of cell cycle regulators in tumor formation in transgenic mice expressing the human neurotropic virus, JCV, early protein. J Cell Biochem 67: 223-230, 1997.
    • (1997) J Cell Biochem , vol.67 , pp. 223-230
    • Krynska, B.1    Gordon, J.2    Otte, J.3    Franks, R.4    Knobler, R.5    DeLuca, A.6    Giordano, A.7    Khalili, K.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.