메뉴 건너뛰기




Volumn 8, Issue 6, 2006, Pages 452-457

The interaction of serotonin transporter gene polymorphisms and early adverse life events on vulnerability for major depression

Author keywords

[No Author keywords available]

Indexed keywords

FLUVOXAMINE; MILNACIPRAN; MONOAMINE OXIDASE INHIBITOR; PAROXETINE; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRICYCLIC ANTIDEPRESSANT AGENT;

EID: 33845914341     PISSN: 15233812     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11920-006-0050-y     Document Type: Review
Times cited : (39)

References (43)
  • 2
    • 0032145210 scopus 로고    scopus 로고
    • The spectrums of behaviors influenced by serotonin
    • Lucki I: The spectrums of behaviors influenced by serotonin. Biol Psychiatry 1998, 44:151-162.
    • (1998) Biol Psychiatry , vol.44 , pp. 151-162
    • Lucki, I.1
  • 3
    • 0033765025 scopus 로고    scopus 로고
    • The role of serotonergic and noradrenergic systems in the pathophysiology of depression and anxiety disorders
    • Ressler KJ, Nemeroff CB. The role of serotonergic and noradrenergic systems in the pathophysiology of depression and anxiety disorders. Depress Anxiety 2000, 12:2-19.
    • (2000) Depress Anxiety , vol.12 , pp. 2-19
    • Ressler, K.J.1    Nemeroff, C.B.2
  • 4
    • 0023737084 scopus 로고
    • Marked reduction in the number of platelet-tritiated imipramine binding sites in geriatric depression
    • Nemeroff CB, Knight DL, Krishnan RR, et al.: Marked reduction in the number of platelet-tritiated imipramine binding sites in geriatric depression. Arch Gen Psychiatry 1988, 45:919-923.
    • (1988) Arch Gen Psychiatry , vol.45 , pp. 919-923
    • Nemeroff, C.B.1    Knight, D.L.2    Krishnan, R.R.3
  • 5
    • 30044435499 scopus 로고    scopus 로고
    • Lower serotonin transporter binding potential in the human brain during major depressive episodes
    • Parsey RV, Hastings RS, Oquendo MA, et al.: Lower serotonin transporter binding potential in the human brain during major depressive episodes. Am J Psychiatry 2006, 163:.52-58.
    • (2006) Am J Psychiatry , vol.163 , pp. 52-58
    • Parsey, R.V.1    Hastings, R.S.2    Oquendo, M.A.3
  • 6
    • 33645799676 scopus 로고    scopus 로고
    • Genetics of emotional regulation: The role of the serotonin transporter in neural function
    • Hariri AR, Holmes A: Genetics of emotional regulation: the role of the serotonin transporter in neural function. Trends Cogni Sci 2006, 10:182-191.
    • (2006) Trends Cogni Sci , vol.10 , pp. 182-191
    • Hariri, A.R.1    Holmes, A.2
  • 7
    • 0032401073 scopus 로고    scopus 로고
    • Reduced brain serotonin transporter availability in major depression as measured by [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and single photon emission computed tomography
    • Malison RT, Price LH, Berman R, et al.: Reduced brain serotonin transporter availability in major depression as measured by [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and single photon emission computed tomography. Biol Psychiatry 1998, 44:1090-1098.
    • (1998) Biol Psychiatry , vol.44 , pp. 1090-1098
    • Malison, R.T.1    Price, L.H.2    Berman, R.3
  • 8
    • 0035669353 scopus 로고    scopus 로고
    • Serotonin 1A receptors, serotonin transporter binding and serotonin transporter mRNA expression in the brainstem of depressed suicide victims
    • Arango V, Underwood MD, Boldrini M, et al.: Serotonin 1A receptors, serotonin transporter binding and serotonin transporter mRNA expression in the brainstem of depressed suicide victims. Neuropsychopharmacology 2001, 25:892-903.
    • (2001) Neuropsychopharmacology , vol.25 , pp. 892-903
    • Arango, V.1    Underwood, M.D.2    Boldrini, M.3
  • 9
    • 0030964703 scopus 로고    scopus 로고
    • Alternative splicing of the human serotonin transporter gene
    • Bradley CC. Blakely RD: Alternative splicing of the human serotonin transporter gene. J Neurochem 1997, 69:1356-1367.
    • (1997) J Neurochem , vol.69 , pp. 1356-1367
    • Bradley, C.C.1    Blakely, R.D.2
  • 10
    • 0029895783 scopus 로고    scopus 로고
    • Allelic variation of human serotonin transporter gene expression
    • Heils A, Lesch KP: Allelic variation of human serotonin transporter gene expression. J Neurochem 1996, 66:2621-2624.
    • (1996) J Neurochem , vol.66 , pp. 2621-2624
    • Heils, A.1    Lesch, K.P.2
  • 11
    • 0032191771 scopus 로고    scopus 로고
    • Imaging of the serotonergic system: Interactions of neuroanatomical and functional abnormalities of depression
    • Staley JK, Malison RT, Innis RB: Imaging of the serotonergic system: interactions of neuroanatomical and functional abnormalities of depression. Biol Psychiatry 1998, 44:534-549.
    • (1998) Biol Psychiatry , vol.44 , pp. 534-549
    • Staley, J.K.1    Malison, R.T.2    Innis, R.B.3
  • 12
    • 0034176712 scopus 로고    scopus 로고
    • A relationship between serotonin transporter genotype, an in vivo protein expression and alcohol neurotoxicity
    • Heinz A, Jones DW, Mazzanti C, et al.: A relationship between serotonin transporter genotype, an in vivo protein expression and alcohol neurotoxicity. Biol Psychiatry 2000, 47:643-649.
    • (2000) Biol Psychiatry , vol.47 , pp. 643-649
    • Heinz, A.1    Jones, D.W.2    Mazzanti, C.3
  • 13
    • 33644994740 scopus 로고    scopus 로고
    • The 5HTTLPR polymorphism of the serotonin transporter gene is associated with affective temperaments as measured by TEMPS-A
    • Gonda X, Rihmer Z, Zsombok T, et al.: The 5HTTLPR polymorphism of the serotonin transporter gene is associated with affective temperaments as measured by TEMPS-A. J Affect Disord 2006, 91:125-131.
    • (2006) J Affect Disord , vol.91 , pp. 125-131
    • Gonda, X.1    Rihmer, Z.2    Zsombok, T.3
  • 14
    • 33748559016 scopus 로고    scopus 로고
    • Serotonin transporter polymorphism mediates vulnerability to loss of incentive motivation following acute tryptophan depletion
    • In press
    • Roiser JP, Blackwell AD, Cools R, et al.: Serotonin transporter polymorphism mediates vulnerability to loss of incentive motivation following acute tryptophan depletion. Neuropsychopharmacology 2006, In press.
    • (2006) Neuropsychopharmacology
    • Roiser, J.P.1    Blackwell, A.D.2    Cools, R.3
  • 15
    • 13244259560 scopus 로고    scopus 로고
    • A susceptibility gene for affective disorders and the response of the human amygdala
    • Hariri A, Drabant E, Munoz K, et al.: A susceptibility gene for affective disorders and the response of the human amygdala. Arch Gen Psychiatry 2005, 62:146-152.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 146-152
    • Hariri, A.1    Drabant, E.2    Munoz, K.3
  • 16
    • 33244483082 scopus 로고    scopus 로고
    • Serotonin transporter gene promoter region polymorphism associated with poststroke depression
    • Ramasubbu R, Tobias R, Buchan A, et al.: Serotonin transporter gene promoter region polymorphism associated with poststroke depression. J Neuropsychiatry Clin Neurosci 2006, 18:96-99.
    • (2006) J Neuropsychiatry Clin Neurosci , vol.18 , pp. 96-99
    • Ramasubbu, R.1    Tobias, R.2    Buchan, A.3
  • 17
    • 0242552727 scopus 로고    scopus 로고
    • Is there an association between serotonin transporter gene polymorphism and family history of depression?
    • Joiner T, Johnson F, Soderstrom K, et al.: Is there an association between serotonin transporter gene polymorphism and family history of depression? J Affect Disord 2003, 77:273-275.
    • (2003) J Affect Disord , vol.77 , pp. 273-275
    • Joiner, T.1    Johnson, F.2    Soderstrom, K.3
  • 18
    • 0344896572 scopus 로고    scopus 로고
    • 5-HTTLPR polymorphism of the serotonin transporter gene predicts non-remission in major depression patients treated with citalopram in a 12-week follow up study
    • Arias B, Rosa C, Gasto C, et al.: 5-HTTLPR polymorphism of the serotonin transporter gene predicts non-remission in major depression patients treated with citalopram in a 12-week follow up study. J Clin Psychopharmacol 2003, 23:563-567.
    • (2003) J Clin Psychopharmacol , vol.23 , pp. 563-567
    • Arias, B.1    Rosa, C.2    Gasto, C.3
  • 19
    • 33646931895 scopus 로고    scopus 로고
    • Serotonin transporter polymorphism and clinical response to sertraline across ethnicities
    • Hong NG, Easteal S, Tan S, et al.: Serotonin transporter polymorphism and clinical response to sertraline across ethnicities. Prog Neuropsychopharmacol Biol Psychiatry 2006, 30:953-957.
    • (2006) Prog Neuropsychopharmacol Biol Psychiatry , vol.30 , pp. 953-957
    • Hong, N.G.1    Easteal, S.2    Tan, S.3
  • 20
    • 23144436298 scopus 로고    scopus 로고
    • The influence of serotonin transporter promoter polymorphism (SERTPR) and other polymorphism of the serotonin pathway on the efficacy of antidepressant treatments
    • Serretti A, Benedetti F, Zanardi R, et al.: The influence of serotonin transporter promoter polymorphism (SERTPR) and other polymorphism of the serotonin pathway on the efficacy of antidepressant treatments. Prog Neuropsychopharmacol Biol Psychiatry 2005, 29:1074-1084.
    • (2005) Prog Neuropsychopharmacol Biol Psychiatry , vol.29 , pp. 1074-1084
    • Serretti, A.1    Benedetti, F.2    Zanardi, R.3
  • 21
    • 23144464776 scopus 로고    scopus 로고
    • Initial conditions of psychotropic drug response: Studies of serotonin transporter long promoter region (5-HTTLPR), serotonin transporter efficiency, cytokine and kinase gene expression relevant to depression and antidepressant outcome
    • Rausch J: Initial conditions of psychotropic drug response: studies of serotonin transporter long promoter region (5-HTTLPR), serotonin transporter efficiency, cytokine and kinase gene expression relevant to depression and antidepressant outcome. Prog Neuropsychopharmacol Biol Psychiatry 2005, 29:1046-1061.
    • (2005) Prog Neuropsychopharmacol Biol Psychiatry , vol.29 , pp. 1046-1061
    • Rausch, J.1
  • 22
    • 0034677021 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphism and antidepressant response
    • Kim DK, Lim SW, Lee S, et al.: Serotonin transporter gene polymorphism and antidepressant response. Neuroreport 2000, 11:215-219.
    • (2000) Neuroreport , vol.11 , pp. 215-219
    • Kim, D.K.1    Lim, S.W.2    Lee, S.3
  • 23
    • 0036140426 scopus 로고    scopus 로고
    • Influence of the serotonin transporter gene-linked polymorphic region on the antidepressant response to fluvoxamine in Japanese depressed patients
    • Yoshida K, Ito K, Sato K, et al.: Influence of the serotonin transporter gene-linked polymorphic region on the antidepressant response to fluvoxamine in Japanese depressed patients. Prog Neuropsychopharmacol Biol Psychiatry 2002, 26:383-386.
    • (2002) Prog Neuropsychopharmacol Biol Psychiatry , vol.26 , pp. 383-386
    • Yoshida, K.1    Ito, K.2    Sato, K.3
  • 24
    • 4444308435 scopus 로고    scopus 로고
    • Prediction of antidepressant response to milnacipran by norepinephrine transporter gene polymorphisms
    • Yoshida K, Takahashi H, Higuchi H, et al.: Prediction of antidepressant response to milnacipran by norepinephrine transporter gene polymorphisms. Am J Psychiatry 2004, 161:1575-1580.
    • (2004) Am J Psychiatry , vol.161 , pp. 1575-1580
    • Yoshida, K.1    Takahashi, H.2    Higuchi, H.3
  • 25
    • 13444254085 scopus 로고    scopus 로고
    • Alterations in diurnal cortisol rhythm and acoustic startle response in non-human primates with adverse rearing
    • Sanchez MM, Noble PM, Lyon CK, et al.: Alterations in diurnal cortisol rhythm and acoustic startle response in non-human primates with adverse rearing. Biol Psychiatry 2005, 57:373-381.
    • (2005) Biol Psychiatry , vol.57 , pp. 373-381
    • Sanchez, M.M.1    Noble, P.M.2    Lyon, C.K.3
  • 27
    • 85047699571 scopus 로고    scopus 로고
    • Early experience and serotonin transporter gene variation interact to influence primate CNS function
    • Bennett AJ, Lesch KP, Heils A, et al.: Early experience and serotonin transporter gene variation interact to influence primate CNS function. Mol Psychiatry 2002, 7:118-122.
    • (2002) Mol Psychiatry , vol.7 , pp. 118-122
    • Bennett, A.J.1    Lesch, K.P.2    Heils, A.3
  • 28
    • 0035875146 scopus 로고    scopus 로고
    • The role of childhood trauma in the neurobiology of mood and anxiety disorders: Preclinical and clinical studies
    • Heim C, Nemeroff CB: The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies. Biol Psychiatry 2001, 49:1023-1039.
    • (2001) Biol Psychiatry , vol.49 , pp. 1023-1039
    • Heim, C.1    Nemeroff, C.B.2
  • 29
    • 12144287589 scopus 로고    scopus 로고
    • Rearing conditions and rh5-HTTLPR interact to influence limbic-hypothalamic-pituitary-adrenal axis response to stress in infant macaques
    • Barr CS, Newman T, Shannon C, et al.: Rearing conditions and rh5-HTTLPR interact to influence limbic-hypothalamic-pituitary-adrenal axis response to stress in infant macaques. Biol Psychiatry 2004, 55:733-738.
    • (2004) Biol Psychiatry , vol.55 , pp. 733-738
    • Barr, C.S.1    Newman, T.2    Shannon, C.3
  • 30
    • 1842533140 scopus 로고    scopus 로고
    • The interrelationship of neuroticism, sex and stressful life events in the prediction of episodes of major depression
    • Kendler KS, Kuhn J, Prescott C: The interrelationship of neuroticism, sex and stressful life events in the prediction of episodes of major depression. Am J Psychiatry 2004, 161:631-636.
    • (2004) Am J Psychiatry , vol.161 , pp. 631-636
    • Kendler, K.S.1    Kuhn, J.2    Prescott, C.3
  • 31
    • 0037624040 scopus 로고    scopus 로고
    • Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene
    • Caspi A, Sugden K, Moffit T, et al.: Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003, 301:386-389.
    • (2003) Science , vol.301 , pp. 386-389
    • Caspi, A.1    Sugden, K.2    Moffit, T.3
  • 32
    • 33644753812 scopus 로고    scopus 로고
    • Life events, first depression onset and the serotonin transporter gene
    • Wilhem K, Mitchell P, Niven H, et al.: Life events, first depression onset and the serotonin transporter gene. Br J Psychiatry 2006, 188:210-215.
    • (2006) Br J Psychiatry , vol.188 , pp. 210-215
    • Wilhem, K.1    Mitchell, P.2    Niven, H.3
  • 33
    • 18244389951 scopus 로고    scopus 로고
    • The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression
    • Kendler K, Kuhn J, Vittum J, et al.: The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression. Arch Gen Psychiatry 2005, 62:529-535.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 529-535
    • Kendler, K.1    Kuhn, J.2    Vittum, J.3
  • 34
    • 4143123257 scopus 로고    scopus 로고
    • A case control and family-based association study of the 5-HTTLPR in pediatric-onset depressive disorders
    • Nobile M, Giulia M, Giordia R, et al.: A case control and family-based association study of the 5-HTTLPR in pediatric-onset depressive disorders. Biol Psychiatry 2004, 56:292-295.
    • (2004) Biol Psychiatry , vol.56 , pp. 292-295
    • Nobile, M.1    Giulia, M.2    Giordia, R.3
  • 35
    • 10344238087 scopus 로고    scopus 로고
    • Social supports and serotonin transporter gene moderate depression in maltreated children
    • Kaufman J, Yang BZ, Douglas-Palumberi H, et a1.: Social supports and serotonin transporter gene moderate depression in maltreated children. Proc Natl Acad Sci U S A 2004, 101:17316-17321.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 17316-17321
    • Kaufman, J.1    Yang, B.Z.2    Douglas-Palumberi, H.3
  • 36
    • 33645337891 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children
    • Kaufman J, Yang BZ, Douglas-Palumberi H, et al.: Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children. Biol Psychiatry 2006, 59:673-680.
    • (2006) Biol Psychiatry , vol.59 , pp. 673-680
    • Kaufman, J.1    Yang, B.Z.2    Douglas-Palumberi, H.3
  • 37
    • 0026542671 scopus 로고
    • The role of the amygdala in fear-potentiated startle: Implications for animal models of anxiety
    • Davis M: The role of the amygdala in fear-potentiated startle: implications for animal models of anxiety. Trends Pharmacol Sci 1992, 13:35-41.
    • (1992) Trends Pharmacol Sci , vol.13 , pp. 35-41
    • Davis, M.1
  • 38
    • 22844433107 scopus 로고    scopus 로고
    • 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: A genetic susceptibility mechanism for depression
    • Pezawas L, Meyer-Lindberg A, Drabant E, et al.: 5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression. Nat Neurosci 2005, 8:828-834.
    • (2005) Nat Neurosci , vol.8 , pp. 828-834
    • Pezawas, L.1    Meyer-Lindberg, A.2    Drabant, E.3
  • 39
    • 16644400562 scopus 로고    scopus 로고
    • Amygdala prefrontal coupling depends on a genetic variation of the serotonin transporter
    • Heinz A, Braus D, Smolka M, et al.: Amygdala prefrontal coupling depends on a genetic variation of the serotonin transporter. Nat Neurosci 2005, 8:20-21.
    • (2005) Nat Neurosci , vol.8 , pp. 20-21
    • Heinz, A.1    Braus, D.2    Smolka, M.3
  • 40
    • 0034667296 scopus 로고    scopus 로고
    • Effects of early adverse experiences on brain structure and function: Clinical implications
    • Kaufman J, Plotsky P, Nemeroff CB, et al.: Effects of early adverse experiences on brain structure and function: clinical implications. Biol Psychiatry 2000, 48:778-790.
    • (2000) Biol Psychiatry , vol.48 , pp. 778-790
    • Kaufman, J.1    Plotsky, P.2    Nemeroff, C.B.3
  • 41
    • 0032976603 scopus 로고    scopus 로고
    • Corticosterone regulation of serotonin transporter and 5-HT1A receptor expression in the aging brain
    • Maines LW, Keck J, Smith J, et al.: Corticosterone regulation of serotonin transporter and 5-HT1A receptor expression in the aging brain. Synapse 1999, 32:58-66.
    • (1999) Synapse , vol.32 , pp. 58-66
    • Maines, L.W.1    Keck, J.2    Smith, J.3
  • 42
    • 0028069480 scopus 로고
    • Corticotropin-releasing factor and neuropeptide Y: Role in emotional integration
    • Heilig M, Koob GF, Ekman R, et al.: Corticotropin-releasing factor and neuropeptide Y: role in emotional integration. Trends Neurosci 1994, 17:80-85.
    • (1994) Trends Neurosci , vol.17 , pp. 80-85
    • Heilig, M.1    Koob, G.F.2    Ekman, R.3
  • 43
    • 0034302849 scopus 로고    scopus 로고
    • 5-HT-HPA interactions in two models of transgenic mice relevant to major depression
    • Lanfumey L, Mannoury La Cour C, Froger N, Hamon M: 5-HT-HPA interactions in two models of transgenic mice relevant to major depression. Neurochem Res 2000, 25:1199-1206.
    • (2000) Neurochem Res , vol.25 , pp. 1199-1206
    • Lanfumey, L.1    Mannoury La Cour, C.2    Froger, N.3    Hamon, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.